职称职务：教授、生态学系主任
Appointment: Professor and Chair of Department of Ecology
学科专业：生态学、动物学、进化生物学
Research Fields: Ecology, Zoology, Evolutionary Biology研究方向：动物多样性及其分子进化机制
Research Interests: Animal Diversity and Molecular Evolution
实验室位置：生命科学院大楼5119室
Location: College of Life Sciences, Room 5119
联系方式：(Office)； (Lab)
Email: huabinzhao@@whu.edu.cn (发邮件时请删除一个@）
Lab Website: http://animal-evolution.whu.edu.cn/





Huabin Zhao, Ph.D, Professor and Chair of Department of Ecology
Department of Ecology,
College of Life Sciences, Wuhan University299 Bayi Road, Wuhan, Hubei 430072, China
Tel: (86) 27 6875 3526; Fax: (86) 27 6875 2397
Email: huabinzhao (at) whu.edu.cn

个人简介：
安徽肥西人；2009年毕业于中国科学院动物研究所，生态学专业，获理学博士学位；2009-2012年在美国密歇根大学生态与进化生物学系做博士后研究；2012年2月至今为武汉大学生命科学学院教授。
Background：
In 2009, I received my PhD in ecology at the Institute of Zoology, Chinese Academy of Sciences. From Sept. 2009 to Jan. 2012, I worked as a postdoctoral fellow in the department of Ecology and Evolutionary Biology at University of Michigan, USA. In Feb. 2012, I joined College of Life Sciences, Wuhan University and started my lab as a Principal Investigator (professor of zoology and ecology).

荣誉及获奖：
国家****青年拔尖人才计划（2016）
国家优秀青年科学基金（2017）

教学情况：
《进化生物学》48学时，本科生；
《动物生物学》54学时，本科生；
《分子生态学》36学时，研究生
Courses:
EVOLUTIONARY BIOLOGY for undergraduate students;
ANIMAL BIOLOGY for undergraduate students;
MOLECULAR ECOLOGY for graduate students.

研究概述：
自然选择是现代生物学的核心理论，也是生物演化的关键驱动力。我们的主要研究领域是，用自然选择理论解析动物物种多样性的分子遗传学基础。具体研究方向包括：(1）解析动物行为、生理、形态多样性的进化历史；主要以蝙蝠为研究系统；（2）动物食性多样性的分子进化与适应；此研究方向不局限于某个动物类群，但我们比较熟悉鸟类和哺乳动物。
Research Overview:
The theory of natural selection is the centerpiece of biology and also the key driving force of biological evolution. Our major research interests are to explore the molecular genetic mechanisms underlying the enormous diversity of animal behaviours and physiological functions, using the theory of natural selection as an explanatory framework.
(1) We decipher the evolutionary processes that have generated enormous diversity of form and behaviour well-known in nature, using bats as a model study group. Bats are mammals but possess many unique features distinctive from other mammals, such as powered flight, laryngeal echolocation, and strong immunity conferring greater capacity to co-exist with many deadly viruses. Meanwhile, bats exhibit enormous diversity in diet, behaviour, and morphological and physiological traits. We attempt to uncover molecular evolutionary history of all these traits by comparing bats with other mammals. In this line of research, we try to focus on bats, but we are open to study birds, reptiles, and other mammals in rare cases.
(2) We develop or test evolutionary hypotheses on the evolution of sensory systems across vertebrates within a phylogenetic framework. Humans and other mammals use the five traditional senses of taste, sight, smell, sound, and touch to perceive the world around us. Much of our current work is to discover molecular basis of functional evolution of sensory genes, using vertebrate taste receptor genes as a model study system. We use an interdisciplinary approach that includes molecular evolution, comparative genomics, population genetics, protein engineering, cell culture, and calcium mobilization assay. In this line of research, we are not limited to a particular group of animals, but we are most familiar with birds and mammals in general, and bats in particular.

主持课题项目：
1. 国家自然科学基金优秀青年科学基金（**), 2018-2020；
2. 国家****青年拔尖人才项目 (), 2018-2020；
3. 国家自然科学基金面上项目（**), 2017-2020；
4. 国家自然科学基金青年项目（**), 2014-2016；
5. 国家自然科学基金重大研究计划培育项目（**), 2014-2016.
6. 湖北省****基金（2019CFA075），2019-2021.

代表性论文（Selected Publications) (此处不再更新，最新论文及其PDF全文下载链接 http://animal-evolution.whu.edu.cn/publications.htm)

1)Yan H^#, Jiao H^#, Liu Q, Zhang Z, Xiong Q, Wang BJ, Wang X, Guo M, Wang LF, Lan K*, Chen Y*, and Zhao H* (2021). ACE2 receptor usage reveals variation in susceptibility to SARS-CoV and SARS-CoV-2 infection among bat species. Nature Ecology & Evolution. 5(5):600-608.
2) Jiao H^#, Xie HW^#, Zhang L^#, Zhuoma N, Jiang P, and Zhao H* (2021). Loss of sweet taste despite the conservation of sweet receptor genes in insectivorous bats. Proceedings of the National Academy of Sciences of the United States of America. 118(4):e.
3)Zou D, Tian S, Zhang T, Zhuoma N, Wu G, Wang M, Dong L, Rossiter SJ, and Zhao H* (2021). Vulture genomes reveal molecular adaptations underlying obligate scavenging and low levels of genetic diversity. Molecular Biology and Evolution. In press.
4) Zhao H* (2020). COVID-19 drives new threat to bats in China. Science. 367(6485):1436. DOI: 10.1126/science.abb3088 (Letter)
5) Wang K, Tian S, Galindo-González J, Dávalos LM, Zhang Y, and Zhao H* (2020). Molecular adaptation and convergent evolution of frugivory in Old World and neotropical fruit bats. Molecular Ecology. 29(22):4366-4381.

6)Wang BJ, Xia JM, Wang Q, Yu JL, Song Z, and Zhao H* (2020). Diet and adaptive evolution of alanine-glyoxylate aminotransferase mitochondrial targeting in birds. Molecular Biology and Evolution.37(3):786-798.
7) Jiao H^#, Zhang L^#, Xie HW, Simmons NB, Liu H, and Zhao H*(2019). Trehalase gene as a molecular signature of dietary diversification in mammals. Molecular Biology and Evolution.36:2171-2183.
8) Jiao H, Wang Y, Zhang L, Jiang P*, and Zhao H* (2018). Lineage-specific duplication and adaptive evolution of bitter taste receptor genes in bats. Molecular Ecology. 27:4475–4488.
9) Wu J^#, Jiao H^#, Simmons NB, Lu Q*, and Zhao H* (2018). Testing the sensory tradeoff hypothesis in New World bats. Proceedings of the Royal Society B: Biological Sciences. 285:**. (Cover Story)
10) Zhang Y, Jiao Y, Jiao H, Zhao H*, and Zhu YX* (2017). Two-step functional innovation of the stem-cell factors WUS/WOX5 during plant evolution. Molecular Biology and Evolution. 3:640-653.
11) Li K^#, Hong W^#, Jiao H, Wang GD, Rodriguez KA, Buffenstein R, Zhao Y, Nevo E*, and Zhao H* (2015). Sympatric speciation revealed by genome-wide divergence in the blind mole rat Spalax. Proceedings of the National Academy of Sciences of the United States of America. 112:11905-11910.
12)Zhao H, Li J, and Zhang J* (2015). Molecular evidence for the loss of three basic tastes in penguins. Current Biology. 25:R141-R142.
13) Hong W, and Zhao H* (2014). Vampire bats exhibit evolutionary reduction of bitter taste receptor genes common to other bats. Proceedings of the Royal Society B: Biological Sciences. 281: **.
14) Zhao H*, and Zhang J* (2012). Mismatches between feeding ecology and taste receptor evolution: An inconvenient truth. Proceedings of the National Academy of Sciences of the United States of America. 109:E1464. (Letter to Editor)
15) Zhao H, Xu D, Zhang S*, and Zhang J* (2011). Widespread losses of vomeronasal signal transduction in bats. Molecular Biology and Evolution. 28:7-12.
16) Zhao H, Zhou Y, Pinto CM, Charles-Dominique P, Galindo-Gonzalez J, Zhang S*, and Zhang J* (2010). Evolution of the sweet taste receptor gene Tas1r2 in bats. Molecular Biology and Evolution. 27:2642-2650.
17) Zhao H, Yang JR, Xu H, and Zhang J* (2010). Pseudogenization of the umami taste receptor gene Tas1r1 in the giant panda coincided with its dietary switch to bamboo. Molecular Biology and Evolution. 27:2669-2673.
18) Zhao H, Rossiter SJ*, Teeling EC*, Li C, Cotton JA, and Zhang S* (2009). The evolution of color vision in nocturnal mammals. Proceedings of the National Academy of Sciences of the United States of America. 106:8980-8985.

实验室成员：
见网页：http://animal-evolution.whu.edu.cn/tdcy/xycy.htm

招生招聘：
本实验室主要用分子遗传学、比较基因组学、细胞生物学、生物信息学等技术手段，检测或提出与动物行为与生理功能多样性相关的进化假说。热忱欢迎对动物学、分子进化、分子生态学、比较基因组学等研究方向感兴趣的有志青年加入。
1）每年拟接收0-2名本科生：将攻读动物学、生态学或进化生物学领域的博士学位；有保研意向的大二及大三学生。
2）每年拟招收2-3名硕士生：仅招收硕博连读生；报考选择：动物学、分子遗传学方向；生态学、动物生态学方向。
3）每年拟招收1-2名博士生：学习年限为4-6年；报考选择：动物学、比较基因组学方向；生态学、生态基因组学方向。



武汉大学赵华斌教授常年招聘博士后和研究助理（2019年6月12日）