职称职务：教授、博士生导师、副院长
学　　历：理学博士
专　　业：病毒学、免疫学
实验室位置：生科院大楼5012
联系电话：**(办公室)；**(实验室)
Email：zspan@whu.edu.cn

教育经历
1988－1991卫生部兰州生物制品研究所医学硕士
1997－2001武汉大学理学博士
2003－2005美国加州大学(UCI)博士后

研究领域
抗病毒免疫和病毒基因工程疫苗；病毒基因组复制及其调控

获资助项目
国家973、国家863计划、国家自然科学基金、回国留学人员基金、湖北省和武汉市科技攻关等。

近期代表性论文
1.MengchengLuo,XiaoQu,RuangangPan,DandanZhu,YuanZhang,JianguoWu,ZishuPan*.(2011).Thevirus-inducedsignalingadaptormoleculeenhancesDNA-raisedimmuneprotectionagainstH5N1influenzavirusinfectioninmice.Vaccine29,2561-2567.

2.ChaoWan,LiYi,ZhenhuaYang,JunYang,HuabinShao,ChuyuZhang,ZishuPan*.(2010).TheToll-likereceptoradaptormoleculeTRIFenhancesDNAvaccinationagainstclassicalswinefever.VeterinaryImmunologyandImmunopathology137,47–53.3.XiufenZou,XueshuangXiang,YanChen,TaoPeng,XuelianLuo,ZishuPan*.(2010).UnderstandinginhibitionofviralproteinsontypeIIFNsignalingpathwayswithmodelingandoptimization.JournalofTheoreticalBiology265,691–703.

4.PanTao,MengchengLuo,RuangangPan,DaweiLing,SiyuZhou,PoTien,ZishuPan*.(2009).EnhancedprotectiveimmunityagainstH5N1influenzaviruschallengebyvaccinationwithDNAexpressingachimerichemagglutininincombinationwithanMHCclassI-restrictedepitopeofnucleoproteininmice.AntiviralResearch81,253-260.

5.XuelianLuo,RuangangPan,ChaoWan,XinfengLiu,JianguoWu,ZishuPan*.(2009).GlycosylationofclassicalswinefevervirusE(rns)isessentialforbindingdouble-strandedRNAandpreventinginterferon-betainduction.VirusResearch146,135-139.

6.GuoyuanWen,JinnuoXue,YanpingShen,ChuyuZhang,ZishuPan*.(2009).Characterizationofclassicalswinefevervirus(CSFV)nonstructuralprotein3(NS3)helicaseactivityanditsmodulationbyCSFVRNA-dependentRNApolymerase.VirusResearch141,63-70.

7.PanTao,MengchengLuo,DandanZhu,SanfuQu,ZhenhuaYang,MengGao,DeyinGuo,ZishuPan*.(2009).Virus-likeparticlevaccinecomprisedoftheHA,NA,andM1proteinsofanavianisolatedH5N1influenzavirusinducesprotectiveimmunityagainsthomologousandheterologousstrainsinmice.ViralImmunology22,273-281.

8.PanTao,LiDai,MengchengLuo,FangqiangTang,PoTien,ZishuPan*.(2009).Analysisofsynonymouscodonusageinclassicalswinefevervirus.VirusGenes38,104-12.

9.MengchengLuo,PanTao,JunweiLi,SiyuZhou,DeyinGuo,ZishuPan*.(2008).ImmunizationwithplasmidDNAencodinginfluenzaAvirusnucleoproteinfusedtoatissueplasminogenactivatorsignalsequenceelicitsstrongimmuneresponsesandprotectionagainstH5N1challengeinmice.JournalofVirologicalMethods154,121–127.

10.ZouX,PengT,PanZ*.(2008).ModelingspecificityintheyeastMAPKsignalingnetworks.JournalofTheoreticalBiology250,139-155.

11.YiWang,QinWang,XiaoluLu,ChuyuZhang,XuezhengFan,ZishuPan,etal.,(2008).12-ntinsertionin3’untranslatedregionleadstoattenuationofclassicswinefevervirusandprotectshostagainstlethalchallenge.Virology374,390-398.

12.PanZ,SikandarS,WitherspoonM,DizonD,LipkinSMetal.,(2008).ImpairedplacentaltrophoblastlineagedifferentiationinAlkbh1(-/-)Mice.DevelopmentalDynamics237,316-327.