研究方向：高分子化学与物理、生物医用高分子、高分子分离与表征
联系电话：**,**
Email:xljiang@whu.edu.cn，xljiang118@hotmail.com
教育与研究经历
1985,9-1989,7成都科技大学优秀生试点班,高分子材料系,学士
1989,9-1992,6成都科技大学高分子材料工程国家重点实验室，硕士(导师：徐僖院士，郑邦乾教授)
1992,7-2000,9上海交通大学化学化工学院高分子材料系助教，讲师，副教授
2000,9-2004,5荷兰阿姆斯特丹大学高分子分析组,博士(导师:Prof.Dr.P.J.Schoenmakers)
2004,6-2006,10荷兰乌特勒支大学药学院药剂系博士后(导师:Prof.Dr.W.E.Hennink)
2006,11-至今：武汉大学化学学院生物医用高分子材料教育部重点实验室（教授，博导）
研究领域与兴趣
1.可控高分子的合成、改性及共轭技术的研究2.基因药物用新型可降解高分子载体的研究3.热敏性可降解高分子药物靶向载体的研究（抗肿瘤药物、多肽蛋白质药物）4.HPLC分离与表征功能高分子学术兼职
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研究方向：高分子化学与物理、生物医用高分子、高分子分离与表征
联系电话：**,**
Email:xljiang@whu.edu.cn，xljiang118@hotmail.com
教育与研究经历
1985,9-1989,7成都科技大学优秀生试点班,高分子材料系,学士
1989,9-1992,6成都科技大学高分子材料工程国家重点实验室，硕士(导师：徐僖院士，郑邦乾教授)
1992,7-2000,9上海交通大学化学化工学院高分子材料系助教，讲师，副教授
2000,9-2004,5荷兰阿姆斯特丹大学高分子分析组,博士(导师:Prof.Dr.P.J.Schoenmakers)
2004,6-2006,10荷兰乌特勒支大学药学院药剂系博士后(导师:Prof.Dr.W.E.Hennink)
2006,11-至今：武汉大学化学学院生物医用高分子材料教育部重点实验室（教授，博导）
研究领域与兴趣
1.可控高分子的合成、改性及共轭技术的研究2.基因药物用新型可降解高分子载体的研究3.热敏性可降解高分子药物靶向载体的研究（抗肿瘤药物、多肽蛋白质药物）4.HPLC分离与表征功能高分子学术兼职
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1.国家自然科学基金资助项目（主任基金，**）：HPLC用于新型生物医用高分子的分离与表征
2.国家自然科学基金资助项目（**）：点击化学合成可降解梳形聚合物及其用于基因载体的研究
3.国家科学基金项目：稳定化热敏性肿瘤靶向高分子纳米胶束载药体系的研究(**)
4.国家科学基金项目：长循环-靶向-逃逸-示踪-多功能高分子胶束药物载体及其与细胞相互作用的研究(**)(2012-2015)
5.国家科学基金项目：多功能化聚合物超分子自组装基因载体系统的研究(**)(2014-2017)
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有机结构分析、功能高分子
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1.J.Liu,Y.-L.Xu,Q.-Z.Yang,C.Li,W.E.Hennink,R.-X.Zhuo,X.-L.Jiang*,ReductionBiodegradableBrushedPDMAEMADerivativesSynthesizedbyATRPandClickChemistryforGeneDelivery,ActaBiomater,2013,9,7758-7766.2.Y.-Y.Ma,X.-L.Jiang*,R.-X.Zhuo,BiodegradableandThermosensitiveMicellesofAmphiphilicPolyaspartamideDerivativesContainingAromaticGroupsforDrugDelivery,J.Polym.Sci.,PartA:Polym.Chem.2013,51,3917-3924.3.X.-G.Huang,X.-L.Jiang*,Q.-Z.Yang,Y.-F.Chu,G.-Y.Zhang,B.Yang,R.-X.Zhuo,Triple-Stimuli(pH/Thermo/Reduction)SensitiveCopolymersforIntracellularDrugDelivery,J.Mater.Chem.B,2013,1,1860-1868.4.G.-Y.Zhang,J.Liu,Q.-Z.Yang,R.-X.Zhuo,X.-L.Jiang*,Disulfide-ContainingBrushedPolyethylenimineDerivativeSynthesizedbyClickChemistryforNonviralGeneDelivery,BioconjugateChem.2012,23,1290-1299.5.X.-L.Jiang*,L.-H.Li,J.Liu,W.E.Hennink,R.-X.Zhuo，FacileFabricationofThermo-ResponsiveandReduction-SensitivePolymericMicellesforAnticancerDrugDelivery,Macromol.Biosci.2012,12,703-711.6.X.-G.Huang,X.-L.Jiang*,R.-X.Zhuo,Microwave-assistedsolid-phasesynthesisofpH-responsivepolyaspartamidederivatives,CarbohydratePolymers,2012,89,788-7947.X.-L.Jiang*,J.Liu,L.Xu,R.-X.Zhuo，Disulfide-ContainingHyperbranchedPolyethylenimineDerivativeviaClickChemistryforNonviralGeneDelivery，Macromol.Chem.Phys.,2011,212,64-71.8.X.-L.Jiang*,Y.-F.Chu,J.Liu,G.-Y.ZhangandR.-X.Zhuo，AqueousSECAnalysisofCationicPolymersassGeneCarriers，ChineseJournalofPolymerScience2011,29(4),421-4269.蒋序林,刘佳,张光彦,杨奇志,卓仁禧,可还原降解的梳型高分子基因载体及其制备方法,中国发明专利,ZL**4.810.X.-L.Jiang*,L.-H.Li,J.Liu,R.-X.Zhuo,Reduction-responsivepolymericmicellesforanticancerdrugdelivery,J.Control.Release,2011,152S1,e36-e37.11.J.Liu,L.Xu,X.-L.Jiang*,W.E.Hennink,X.-M.Wang,R.-X.Zhuo,Disulfide-containingcross-linkedPEIderivativesynthesizedbyclickchemistryfornon-viralgenedelivery,J.Control.Release,2011,152,S1,e157-e15912.Y.Chen,L.-Z.Zhou,Y.Pang,W.Huang,F.Qiu,X.-L.Jiang,X.-Y.Zhu,D.-Y.Yan,andQ.Chen,PhotoluminescentHyperbranchedPoly(amidoamine)Containingβ-CyclodextrinasaNonviralGeneDelivery,BioconjugateChem.2011,22,1162-1170.13.J.Liu,X.-L.Jiang*,L.Xu,X.-M.Wang,W.E.Hennink,R.-X.Zhuo，NovelReductiveCrosslinkedPolyethylenimineDerivativebyClickChemistryforNonviralGeneDelivery,BioconjugateChem.2010,21(10),1827-1835.14.蒋序林,刘佳,徐丽,卓仁禧,还原敏感性聚乙烯亚胺衍生物及其制备方法和应用，中国发明专利，ZL**8.915.L.-H.Li,X.-L.Jiang*,R.-X.Zhuo,SynthesisandCharacterizationofThermoresponsivePolymersContainingReduction-SensitiveDisulfideLinkage,JPolymSciPartA:PolymChem2009,47:5989-5997.蒋序林,李丽花,卓仁禧,还原敏感性的两亲性嵌段共聚物及其胶束,中国发明专利,ZL**7.016.X.-L.Jiang,M.C.Lok,C.F.vanNostrum,W.E.Hennink,Degradable-BrushedpHEMA-pDMAEMASynthesizedviaATRPandClickChemistryforGeneDelivery,BioconjugateChem.,2007,18(6),2077-2084.17.D.F.Vlugt-Wensink,X.-L.Jiang,G.Schotman,G.Kruijtzer,A.Vredenberg,J.T.Chung,Z.Zhang,C.Versluis,D.Ramos,R.Verrijk,W.Jiskoot,D.J.A.Crommelin,W.E.Hennink,“InVitroDegradationBehaviorofMicrospheresBasedonCross-LinkedDextran”,Biomacromolecules,2006,7(11),2983-2990.18.X.-L.Jiang,A.vanderHorst,M.J.vanSteenbergen,N.Akeroyd,C.F.vanNostrum,P.J.SchoenmakersandW.E.Hennink,“Aqueoussize-exclusionchromatographyofcationicpolymersforgenedelivery”,J.ControlledRelease,2006,116(2),e69-e71.19.C.Hiemstra,Z.Y.Zhong,X.-L.Jiang,W.E.Hennink,P.J.DijkstraandJ.Feijen,“PEG–PLLAandPEG–PDLAmultiblockcopolymers:Synthesisandinsituhydrogelformationbystereocomplexation”,J.ControlledRelease,2006,116(2),e17-e19.20.C.Lin,Z.-Y.Zhong,M.C.Lok,X.-L.Jiang,W.E.Hennink,J.F.andJohanF.J.Engbersen，“Linearpoly(amidoamine)swithsecondaryandtertiaryaminogroupsandvariableamountsofdisulfidelinkages:Synthesisandinvitrogenetransferproperties”,J.ControlledRelease,2006,116(2),130-137.21.X.-L.Jiang,A.vanderHorst,M.J.vanSteenbergen,C.F.vanNostrum,P.J.Schoenmakers,W.E.Hennink,“Molar-MassCharacterizationofCationicPolymersforGeneDeliverybyAqueousSECwithOnlineMulti-AngleLightScatteringDetection”,Pharmaceut.Res.,2006，23(3),595-603.22.X.-L.Jiang,A.vanderHorst,V.Lima,P.J.Schoenmakers,“ComprehesiveTwo-DimentionalLiquidChromatographyfortheCharacterizationofFunctionalAcrylatePolymers”,J.Chromatogr.A,2005,1076(1-2),51-61.23.V.LimaV,X.-L.Jiang,J.Brokken-Zijp,P.J.Schoenmakers,B.Klumperman,R.VanDerLinde,“SynthesisandcharacterizationoftelechelicpolymethacrylatesviaRAFTpolymerization”m,J.Polym.Sci.:Polym.Chem.,2005,43(5),959-973.24.X.-L.Jiang,P.J.Schoenmakers,X.-W.Lou,V.Lima,J.L.J.vanDongen,andJ.Brokken-Zijp,“SeparationandCharacterizationofFunctionalPoly(n-ButylAcrylate)byCriticalLiquidChromatography”,J.Chromatogr.A,2004,1055(1-2),123-133.25.H.-Q.Zhang,X.-L.Jiang,R.vanderLinde,“SynthesisofHydroxylEnd-CappedTelechelicPolymerswithPoly(MethylMethacrylate)-block-Poly(n-ButylAcrylate)BackbonesviaAtom-TransferRadicalPolymerisation”,Polymer,2004,45(5),1445-1466.26.X.-L.Jiang,P.J.Schoenmakers,J.L.MvanDongen,X.W.Lou,V.Lima,J.Brokken-Zijp,“Mass-SpectrometricCharacterizationofFunctionalPoly(MethylMethacrylate)inCombinationwithCriticalLiquidChromatography”,Anal.Chem.,2003,75(20),5517-5524.
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