陈浩发布时间：2015年1月11日
受教育经历
1996.9-2000.7?????????????? 北京大学化学与分子工程学院，物理化学专业，获理学学士学位?
2000.9-2006.7.1???????? 北京大学化学与分子工程学院，物理化学专业，获理学博士学位?
博士论文题目：蛋白质结构模拟，导师为来鲁华教授
研究工作经历：?
2006.9-2013.8????????????? 美国乔治华盛顿大学物理系，从事生物物理方向的博士后研究工作，导师为曾辰教授?
2013.11-至今????????????????? 武汉轻工大学教师?
研究方向及主要论文?
一、蛋白质结构模拟及设计?
Hao Chen*, Ping Wei*, Changkang Huang, Lei Tan, Ying Liu, Luhua Lai. Only one protomer is active in the dimer of SARS 3C-like proteinase. Journal of Biology Chemistry 2006; 281:13894-13898Zuqing Zhang, Hao Chen, Luhua Lai. Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential. Bioinformatics 2007; 23: 2218-2225Huanhuan Liang, Hao Chen, Keqiang Fan, Ping Wei, Xianrong Guo, Changwen Jin, Chen Zeng, Chao Tang, Luhua Lai. De Novo Design of βαβ Motif. Angewandte Chemie International Edition 2009; 48: 3301-3303
(*: Both authors contributed equally to this work)?二、计算机虚拟药物设计?
Hao Chen, Rachel Van Duyne, Naigong Zhang, Fatah Kashanchi, Chen Zeng. A novel binding pocket of cyclin-dependent kinase 2. PROTEINS: Structure, Function , and Binformatics 2009; 74: 122-132Hao Chen*, Yunjie Zhao*, Haotiao Li*, Dongyan Zhang, Yanzhao Huang, Qi Shen, Rachel Van Duyne, Fatah Kashanchi, Chen Zeng, Shiyong Liu. Break CDK2/Cyclin E1 interface allosterically with small peptides. PLoS One 2014; 9: e109154.?
(*: Both authors contributed equally to this work)?三、生物布尔网络?
Guanyu Wang, Chenghang Du, Hao Chen, Rahul Simha, Yongwu Rong, Yi Xiao, Chen Zeng. Process-based network decomposition reveals backbone motif structure. Proceedings of the National Academy of Sciences of the United States of America 2010; 107: 10478-10483Chenghang Du*, Hao Chen*, Yunjie Zhao, Chen Zeng. How far and how fast can one move on neutral network? J Theor Comput Chem 2013; 12: **
(*: Both authors contributed equally to this work)?联系方式?
Tel：??????????????????? **?
E-mail：?????????????? surmg@sina.com
受教育经历
1996.9-2000.7?????????????? 北京大学化学与分子工程学院，物理化学专业，获理学学士学位?
2000.9-2006.7.1???????? 北京大学化学与分子工程学院，物理化学专业，获理学博士学位?
博士论文题目：蛋白质结构模拟，导师为来鲁华教授
研究工作经历：?
2006.9-2013.8????????????? 美国乔治华盛顿大学物理系，从事生物物理方向的博士后研究工作，导师为曾辰教授?
2013.11-至今????????????????? 武汉轻工大学教师?
研究方向及主要论文?
一、蛋白质结构模拟及设计?
Hao Chen*, Ping Wei*, Changkang Huang, Lei Tan, Ying Liu, Luhua Lai. Only one protomer is active in the dimer of SARS 3C-like proteinase. Journal of Biology Chemistry 2006; 281:13894-13898Zuqing Zhang, Hao Chen, Luhua Lai. Identification of amyloid fibril-forming segments based on structure and residue-based statistical potential. Bioinformatics 2007; 23: 2218-2225Huanhuan Liang, Hao Chen, Keqiang Fan, Ping Wei, Xianrong Guo, Changwen Jin, Chen Zeng, Chao Tang, Luhua Lai. De Novo Design of βαβ Motif. Angewandte Chemie International Edition 2009; 48: 3301-3303
(*: Both authors contributed equally to this work)?二、计算机虚拟药物设计?
Hao Chen, Rachel Van Duyne, Naigong Zhang, Fatah Kashanchi, Chen Zeng. A novel binding pocket of cyclin-dependent kinase 2. PROTEINS: Structure, Function , and Binformatics 2009; 74: 122-132Hao Chen*, Yunjie Zhao*, Haotiao Li*, Dongyan Zhang, Yanzhao Huang, Qi Shen, Rachel Van Duyne, Fatah Kashanchi, Chen Zeng, Shiyong Liu. Break CDK2/Cyclin E1 interface allosterically with small peptides. PLoS One 2014; 9: e109154.?
(*: Both authors contributed equally to this work)?三、生物布尔网络?
Guanyu Wang, Chenghang Du, Hao Chen, Rahul Simha, Yongwu Rong, Yi Xiao, Chen Zeng. Process-based network decomposition reveals backbone motif structure. Proceedings of the National Academy of Sciences of the United States of America 2010; 107: 10478-10483Chenghang Du*, Hao Chen*, Yunjie Zhao, Chen Zeng. How far and how fast can one move on neutral network? J Theor Comput Chem 2013; 12: **
(*: Both authors contributed equally to this work)?联系方式?
Tel：??????????????????? **?
E-mail：?????????????? surmg@sina.com
