姓 名：
陈桂林 性 别：
男
职 务：
无 职 称：
副研究员
学 位：
博士 通讯地址：
武汉市东湖新技术开发区九峰一路201号
电 话：
邮政编码：
430074
传 真：
电子邮件：
glchen@wbgcas.cn


导师简介：



简要履历：
2019.09 -至今 中国科学院武汉植物园，副研究员
2017.07-2019.08 中国科学院武汉植物园，助理研究员
2014.09-2017.06中国科学院大学（中国科学院武汉植物园），植物学专业，理学博士
2006.09-2013.06 湖北中医药大学，制药工程专业学士/药物化学专业硕士


研究领域：
天然药物化学、分析化学



社会任职：



获奖及荣誉：
2018年，中国科学院武汉植物园“明星员工”荣誉
2018年，中国科学院武汉植物园优秀兼职安全员称号
2017年，中国科学院大学“三好学生”荣誉



代表论著：
1. Chen GL, Xu YB, Wu JL, Li N, Guo MQ. Hypoglycemic and hypolipidemic effects of Moringa oleifera leaves and their functional chemical constituents. Food Chemistry, 2020, 333, 127478.
2. Chen GL, Mutie FM, Xu YB, Saleri FD, Hu GW, Guo MQ. Antioxidant, anti-inflammatory activities and polyphenol profile of Rhamnus prinoides. Pharmaceuticals, 2020, 13, 55.
3. Chen GL, Seukep AJ, Guo MQ. Recent advances in molecular docking for the research and discovery of potential marine drugs. Marine Drugs, 2020, 18, 545.
4. Chen GL, Fan MX, Wu JL, Li N, Guo MQ. Antioxidant and anti-inflammatory properties of flavonoids from lotus plumule. Food Chmistry, 2019, 277, 706-712.
5. Chen GL, Zhu MZ, Guo MQ. Research advances in traditional and modern use of Nelumbo nucifera: Phytochemicals, health promoting activities and beyond. Critical Reviews in Food Science and Nutrition, 2019, 59, 189.
6. Chen GL, Fan MX, Liu Y, Sun BQ, Liu MX, Wu JL, Li N, Guo MQ. Advances in MS based strategies for probing ligand-target interactions: Focus on soft ionization mass spectrometric techniques. Frontiers in Chemistry, 2019, 7, 703.
7. Chen GL, Wu JL, Li N, Guo MQ. Screening for anti-proliferative and anti-inflammatory components from Rhamnus davurica Pall. using bio-affinity ultrafiltration with multiple drug targets. Analytical and Bioanalytical Chemistry, 2018, 410, 3587-3595.
8. Chen GL, Huang BX, Guo MQ. Current advances in screening for bioactive components from medicinal plants by affinity ultrafiltration mass spectrometry. Phytochemical Analysis, 2018, 29, 375-386.
9. Chen GL, Guo MQ. Screening for topoisomerases I inhibitors from herbal medicines combining bioaffinity ultrafiltration and LC-MS. Chinese Medicine, 2018, 13, 19-20.
10. Chen GL, Guo MQ. Rapid re-evaluation of bioactive saponins from Paris polyphylla using affinity ultrafiltration-LC/MS with multiple drug targets. International Journal of Mass Spectrometry 2018, 434, 87-92.
11. Chen GL, Guo MQ. Screening for natural inhibitors of topoisomerases I from Rhamnus davurica by affinity ultrafiltration and high-performance liquid chromatography-mass spectrometry. Frontiers in Plant Science, 2017, 8, 1521.
12. Chen GL, Guo MQ. Rapid screening for α-glucosidase inhibitors from Gymnema sylvestre by affinity ultrafiltration-HPLC-MS. Frontiers in Pharmacology, 2017, 8, 228.
13. Chen GL, Li X, Saleri F, Guo MQ. Analysis of flavonoids in Rhamnus davurica and its antiproliferative activities. Molecules, 2016,21,1536.
14. Chen GL, Tian YQ, Guo MQ. Screening for inhibitors of topoisomerase I from Lycoris radiata by combining ultrafiltration with liquid chromatography/mass spectrometry. Rapid Communications in Mass Spectrometry 2016, 30, 95-99.
15. Xu YB, Chen GL, Guo MQ. Correlations between phytochemical fingerprints of Moringa oleifera leaf extracts and their antioxidant activities revealed by chemometrics analysis. Phytochemical Analysis, 2020.
16. Fan MX, Chen GL, Zhang YL, Nahar F, Sarker SD, Hu GW, Guo MQ. Antioxidant and anti-proliferative properties of Hagenia abyssinica roots and their potentially active components. Antioxidants, 2020, 9, 143.
17. Fan MX, Chen GL, Sun BQ, Wu JL, Li N, Sarker SD, Nahar L, Guo MQ. Screening for natural inhibitors of human topoisomerases from medicinal plants with bio-affinity ultrafiltration and LC–MS. Phytochemistry Reviews, 2020,19,1231-1261.
18. Ding J, Chen GL, Chen GF, Guo MQ. One-pot synthesis of epirubicin-capped silver nanoparticles and their anticancer activity against Hep G2 cells. Pharmaceutics, 2019,11,123.
19. Xu YB, Chen GL, Guo MQ. Antioxidant and anti-inflammatory activities of the crude extracts of Moringa oleifera from kenya and their correlations with flavonoids. Antioxidants, 2019, 8, 296.
20. Zhu MZ, Chen GL, Wu JL, Li N, Liu ZH, Guo MQ. Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants. Phytochemical Analysis, 2018, 29, 365-374.
21. 罗舒予, 陈桂林, 张永丽, 郭明全. 卡塔夫提取物抗菌活性部位筛选及其主要活性成分. 天然产物研究与开发, 2020, 32.



承担科研项目情况：
1.主持国家自然科学基金青年基金项目：基于药物蛋白质组学与多靶点超滤筛选研究匙羹藤干预餐后高血糖的作用机制与活性物质基础，**，20万元，2020.01-2022.12
2.主持湖北省自然科学基金青年基金项目：基于多靶点超滤质谱研究中药匙羹藤降糖的活性物质基础与作用机制，2019CFB254，5万，2019.09-2021.09
3.主持中国科学院青年创新促进会项目：飞龙掌血抗肿瘤活性成分的多靶点筛选与作用机制研究，**，80万元，2020.01-2023.12