姓 名：
张春云 性 别：
男
职 务：
无 职 称：
副研究员
学 位：
博士 通讯地址：
武汉植物园
电 话：
邮政编码：
430074
传 真：
电子邮件：
cyzhang@wbgcas.cn


导师简介：



简要履历：
张春云，88年生，博士，副研究员。2015年6月于华南理工大学硕博连读获工学博士学位。于2015年7月入职中国科学院武汉植物园，先后任职助理研究员、副研究员。2018年4月至2021年4月在美国爱荷华大学公共卫生学院从事博士后研究。近年来主要从事新型有机污染物在生物体内的代谢转化，以及环境污染物暴露相关联的健康效应研究。相关成果在国内外期刊发表论文40余篇。其中以第一/通讯作者在Environmental Science & Technology, Analytical Chemistry, Food Chemistry, Journal of Chromatography A等SCI期刊发表论文20余篇。

2015年7月-至今 中国科学院武汉植物园 助理研究员/副研究员2018年4月-2021年4月 美国爱荷华大学 公共卫生学院 博士后
2010年9月-2015年6月 华南理工大学 轻工与食品学院 博士（硕博连读）
2007年9月-2010年6月 齐鲁工业大学 轻化与环境工程学院 学士


研究领域：
环境分析化学与毒理学、基于质谱技术的非靶标分析及代谢组学分析



社会任职：
长期担任Environmental Science & Technology, Journal of Hazardous Materials, Analytical Chemistry, Journal of Chromatography A, Journal of Cleaner Production等20余种期刊的审稿人。


获奖及荣誉：
2014年，获得华南理工大学优秀博士论文创新基金二等资助
2008年，获得国家励志奖学金



代表论著：
5篇代表性论文：
1.Chun-Yun Zhang, Susanne Flor, Patricia Ruiz, Gabriele Ludewig, Hans-Joachim Lehmler. Characterization of the Metabolic Pathways of 4-Chlorobiphenyl (PCB3) in HepG2 Cells Using the Metabolite Profiles of Its Hydroxylated Metabolites. Environmental Science & Technology 2021, 55, 9052-9062.
2.Chun-Yun Zhang, Susanne Flor, Gabriele Ludewig, Hans-Joachim Lehmler. Atropselective partitioning of polychlorinated biphenyls in a HepG2 cell culture system: experimental and modeling results. Environmental Science & Technology 2020, 54, 13817-13827.
3.Chun-Yun Zhang, Susanne Flor, Patricia Ruiz, Ram Dhakal, Xin Hu, Lynn M. Teesch, Gabriele Ludewig, Hans-Joachim Lehmler. 3,3’-Dichlorobiphenyl is metabolized to a complex mixture of oxidative metabolites, including novel methoxylated metabolites, by HepG2 cells. Environmental Science & Technology, 2020, 54, 12345-12357.
4.Chun-Yun Zhang, Teng-Fei Li, Xin-Sheng Chai, Xian-Ming Xiao. Determination of porosity in shale by double headspace extraction GC analysis. Analytical Chemistry 2015, 87, 11072-111077.
5.Chun-Yun Zhang, Qiong Zhang, Cai-Hong Zhong, Ming-Quan Guo. Volatile fingerprints and biomarkers of three representative kiwifruit cultivars obtained by headspace solid-phase microextraction gas chromatography mass spectrometry and chemometrics. Food Chemistry 2019, 271, 211-215.
其它论文：
6.Chun-Yun Zhang, Neng-Biao Lin, Xin-Sheng Chai, Zhong Li. A rapid method for simultaneously determining ethanol and methanol content in wines by full evaporation headspace gas chromatography. Food Chemistry 2015, 183, 169-172.
7.Chun-Yun Zhang, Xin-Sheng Chai, Xian-Ming Xiao. A simple method for correcting for the presence of minor gases when determining the adsorbed methane content in shale. Fuel 2015, 150:334-338.
8.Chun-Yun Zhang#, Meng-Hui Li#, Ming-Quan Guo. A phase conversion headspace technique for the determination of anti-anaerobic activity of drug candidate based on the metabolic acidity change in culture medium. Journal of Chromatography A 2020, 1621, 461024. (#Co-first author)
9.Chun-Yun Zhang#, Meng-Hui Li#, Gui-Lin Chen, Ming-Quan Guo. In-situ headspace analysis of metabolic carbon dioxide of aerobic bacteria for assessing antimicrobial activity of natural products. Journal of Chromatography A 2019, 1600, 41-45. ((#Co-first author)
10.Chun-Yun Zhang, Ming-Quan Guo. Solvent-saturated solid matrix technique for increasing the efficiency of headspace extraction of volatiles. Journal of Chromatography A 2017, 1511, 9-14.
11.Chun-Yun Zhang, Qiong Zhang, Cai-Hong Zhong, Ming-Quan Guo. Analysis of volatile compounds responsible for kiwifruit aroma by desiccated headspace gas chromatography-mass spectrometry. Journal of Chromatography A 2016, 1440:255-259.
12.Chun-Yun Zhang, Xin-Sheng Chai. A novel multiple headspace extraction gas chromatography method for measuring the diffusion coefficient of methanol in water and olive oil. Journal of Chromatography A 2015, 1385:124-128.
13.Chun-Yun Zhang, Hui-Chao Hu, Xin-Sheng Chai, Pan Lei, Xian-Ming Xiao. Determination of maximal amount of minor gases adsorbed in a shale sample by headspace gas chromatography. Journal of Chromatography A 2014, 1328:80-84.
14.Chun-Yun Zhang, Ling-Ling Li, Xin-Sheng Chai, Donald G. Barnes. Rapid determination of methanol content in paper materials by alkaline extraction coupled with headspace analysis. Journal of Chromatography A 2014, 1350:10-14.
15.Chun-Yun Zhang, Hui-Chao Hu, Xin-Sheng Chai, Pan Lei, Xian-Ming Xiao. A novel method for the determination of adsorption partition coefficient of minor gases in a shale sample by headspace gas chromatography. Journal of Chromatography A 2013, 1310:121-125.
16.Chun-Yun Zhang, Neng-Biao Lin, Xin-Sheng Chai, Zhong Li. Rapid determination of titratable acidity in wines by headspace analysis. Food Analytical Methods 2015, 8(4):893-897.
17.Chun-Yun Zhang, Ming-Quan Guo. Analysis and differentiation of the volatile compounds in red and white wines using desiccated headspace gas chromatography-mass spectrometry coupled with chemometrics. Food Analytical Methods 2017, 10, 3531-3537.
18.Chun-Yun Zhang, Xin-Sheng Chai, Donald G. Barnes. A novel solvent-assisted vapor absorption based headspace analysis technique for the determination of diffusion and solid-air partition coefficients of methanol in paper food packaging materials. Fluid Phase Equilibria 2015, 150:334-338.
19.Chun-Yun Zhang, Carolyn R. Klocke, Pamela J. Lein, Hans-Joachim Lehmler. Disposition of PCB 11 in Mice Following Acute Oral Exposure. Chemical Research in Toxicology 2021, 34, 988-991.
20.Chun-Yun Zhang, Dan Fu, Gui-Lin Chen, Ming-Quan Guo. Comparative and chemometric analysis of correlations between the chemical fingerprints and anti-proliferative activities of ganoderic acids from three Ganoderma species. Phytochemical Analysis 2019, 30, 474-480.
21.Yong-Qiang Tian#, Chun-Yun Zhang#, Ming-Quan Guo. Comparative study on alkaloids and their anti-proliferative activities from three Zanthoxylum species. BMC Complementary and Alternative Medicine 2017, 17, 460. (#Co-First Author)
22.Menghui Li#, Chunyun Zhang#, Guilin Chen, Lutfun Nahar, Satyajit D. Sarker Mingquan Guo. Headspace gas chromatographic method for antimicrobial screening: Minimum inhibitory concentration determination. Journal of Pharmaceutical and Biomedical Analysis, 2020, 181, 113122. (#Co-First Author)
23.Xueshu Li, Chunyun Zhang, Kai Wang, Hans-Joachim Lehmler. Fatty liver and impaired hepatic metabolism alter the congener-specific distribution of polychlorinated biphenyls (PCBs) in mice with a liver-specific deletion of cytochrome P450 reductase. Environmental Pollution, 2020, 266, 115233.
24.Riann Jenay Egusquiza, Maria Elena Ambrosio, Shuyi Gin Wang, Kaelen Marie Kay, Chunyun Zhang, Hans-Joachim Lehmler, Bruce Blumberg. Evaluating the Role of the Steroid and Xenobiotic Receptor (SXR/PXR) in PCB-153 Metabolism and Protection against Associated Adverse Effects during Perinatal and Chronic Exposure in Mice. Environmental Health Perspectives, 2020, 128, 047011.
25.Jing Li, Chun-Yun Zhang, Hui-Chao Hu, Xin-Sheng Chai. Effect of shortening kraft pulping integrated with extended oxygen delignification on bio-refinery process performance of eucalyptus. Bioresource Technology, 2016, 202, 11-124.
26.Yong-Qiang Tian, Chun-Yun Zhang, Ming-Qiang Guo. Comparative analysis of Amaryllidaceae alkaloids from three Lycoris species. Molecules, 2015, 20, 21854-21869.
27.Mingzhi Zhu, Ting Liu, Chunyun Zhang, Ming-Quan Guo. Flavonoids of Lotus (Nelumbo nucifera) seed embryos and their antioxidant potential. Journal of Food Science, 2017, 82, 1834-1841.
28.Hui-Chao Hu, Xin-Sheng Chai, Chun-Yun Zhang, Li-Min Fu, Donald Barnes, Liulian Huang, Lihui Chen. Experimental and kinetic model of methanol formation during oxygen delignification processes of alkaline pulps for air emission control. Holzforchung, 2015, 69, 933-942.
29.Qingqing Guan, Minli Wang, Hua Shang, Chunyun Zhang, Chaohai Wei, Ping Ning, Junjie Gu, Xin-Sheng Chai, X.S. Rapid determination of ethyl laurate from supercritical ethanol-carbon dioxide transesterification by full evaporation headspace gas chromatography. Energy & Fuels, 2014, 28, 6995-6998.
30.Ting Liu, Mingzhi Zhu, Chunyun Zhang, Mingquan Guo. Quantitative analysis and comparison of flavonoids in lotus plumules of four representative lotus cultivars. Journal of Spectroscopy, 2017, DOI: 10.1155/2017/**.



承担科研项目情况：
1.美国爱荷华大学环境与健康科学研究中心（EHSRC）项目，Effect of chronic exposure to real world air pollution on serum markers of inflammation resolution in a preclinical model of Alzheimer’s disease. 2020/04-2021/04，4万美元，已结题，主持
2.国家自然科学基金青年基金，猕猴桃中糖苷键合态C6醇/醛类香气物质的气调游离化机制研究，**，2017/01-2019/12，21万，已结题，主持
3.湖北省自然科学基金，猕猴桃香气物质原位全组分检测机理研究，2016CFB285, 2016/01-2017/12，3万，已结题，主持
4.国家自然科学基金面上项目，基于功能蛋白质组学和超滤质谱技术研究石蒜抗肝癌的作用机制与化学物质基础，**， 2017/01-2020/12，57万，已结题，参加