严琼姣，博士，副研究员
地址：湖北省武汉市东湖新技术开发区光谷一路206号，武汉工程大学化工与制药学院大化工楼1717室院
邮编：430205
Email：yanqiongjiao2@126.com
电话：**

教育背景 2005 - 2008， 武汉理工大学生物材料学， 博士
1996 - 1999， 武汉化工学院化学工艺专业， 硕士
1992 - 1996， 武汉化工学院化学制药专业， 学士
工作履历 2020 - 现在， 武汉工程大学化工与制药学院， 副研究员
2016 - 2019， 武汉理工大学化生学院制药工程系， 副研究员
2016 - 2017， 美国得州大学圣安东尼奥健康科学中心， 访问****
2009 - 2016， 武汉理工大学生物材料与工程研究中心， 副研究员
1999 - 2005， 武汉工程大学化工与制药学院， 工程师
研究领域 （1）药物新剂型与新技术
（2）药物合成与工艺研究
（3）生物医用高分子材料
学术成果 代表性论文：
[1]Jiling Yi, Nan Jiang, Binbin Li, Qiongjiao Yan, Tong Qiu, K. Swaminathan Iyer, Yixia Yin, Honglian Dai, Ali K. Yetisen, Shipu Li. Painful Terminal Neuroma Prevention by Capping PRGD/PDLLA Conduit in Rat Sciatic Nerves. Advanced Science, 2018, 5, **.
[2]Wei Xu, Chao Xu, Qiongjiao Yan, Honglian Dai. The effect of different hydroxyapatite microparticles on osteogenic differentiation of MC3T3-E1 preosteoblasts, Journal of Materials Chemistry B, 2018,6:5234-5242.
[3]Nan Jiang, Yong Wang, YiXia Yin, Ruipeng Wei, Guoliang Ying, Binbin Li, Tong Qiu, Patrick Rijn, Ge Tian, Qiongjiao Yan, Honglian Dai, Henk J Busscher, Shipu Li, Ali K Yetisen, XiaoYu Yang. bFGF and Poly-RGD Cooperatively Establish Biointerface for Stem Cell Adhesion, Proliferation and Differentiation. Advanced Materials Interfaces, 2018, **.
[4]Li BinBin, Qiu Tong, Lyer K.S., Yan QiongJiao, Yin YiXia, Xie LiJuan, Wang XinYu, Li ShiPu. PRGD/PDLLA conduit potentiates rat sciatic nerve regeneration and the underlying molecular mechanism. Biomaterials, 2015,55:44-53.
[5]Yin Yixia, Li Binbin, Yan Qiongjiao, Dai Honglian, Wang Xinyu, Huang Jifeng, Li Shipu. Promotion of peripheral nerve regeneration and prevention of neuroma formation by PRGD/PDLLA/β-TCP conduit: report of two cases. Regenerative Biomaterials, 2015, 2(2): 119-124.
[6]Yixia Yin, Jiling Yi, Lijuan Xie, Qiongjiao Yan, Honglian Dai, Shipu Li*. Synthesis, characterization and biological evaluation of poly [LA-co-(Glc-alt-Lys)] for nerve regeneration scaffold. Front. Mater. Sci., 2014, 8(1): 95-101.
[7]Qiu Tong, Yin YiXia, Li BinBin, Xie LiJuan, Yan QiongJiao, Dai HongLian, Wang XinYu, Li ShiPu. PDLLA/PRGD/β-TCP conduits build the neurotrophin-rich microenvironment suppressing the oxidative stress and promoting the sciatic nerve regeneration. Journal of Biomedical Materials Research Part A, 2014,102:3734-3743.
[8]Jifeng Huang, Jie Xiang, Qiongjiao Yan*, Shipu Li, Lantang Song, Xianhua Cai. Dog tibial nerve regeneration across a 30-mm defect bridged by a PRGD/PDLLA/β-TCP/NGF sustained-release conduit. Journal of Reconstructive Microsurgery, 2013, 29(02):77-88.
[9]Qiu Tong, Yu Chang, Yan QiongJiao, Li ShiPu. Degradable PRGD/PDLLA/β-TCP/NGF composites promote differentiation and regulate gene expression in rat pheochromocytoma cells. Chinese Science Bulletin, 2013,58: 2979-2983.
[10]Yan Qiongjiao, Yin Yixia, Li Binbin. Use new PLGL-RGD-NGF nerve conduits for promoting peripheral nerve regeneration. Biomedical Engineering Online, 2012, doi:10.1186/1475-925X-11-36.
[11]Yin Yixia, Yan Qiongjiao, Yan Yuhua, Chen Xiaoming, Li Shipu*, In vitro biocompatibility assessment of a novel PRGD/PDLLA/NGF composite material. Journal of Wuhan University of Technology-Materials Science Edition, 2011，26(6):1059-1063.
[12]Huang Jifeng, Li Dezhong, Yan Qiongjiao*, Zheng Huayong, Li Shipu. Evaluation of PRGD/FK506/NGF conduits for peripheral nerve regeneration in rats. Neurology India, 2010, 58 (3):384-391.
[13]Qiongjiao Yan, Juan Li, Shipu Li, Yixia Yin，Ping Zhang. Synthesis and RGD peptide modification of poly{(lactic acid)-co-[(glycolic acid)-alt-(L-lysine)]}. E-Polymers, 2008, no. 028:1～12.
[14]陈芬儿，严琼姣, 刘明星,　邵兰英,　户业丽，洛索洛芬钠合成工艺研究Ⅱ.高区域选择性烷基化合成法，中国医药工业杂志，2000, 31(1): 1-2.
[15]陈芬儿，严琼姣，彭作中，张道明，傅晗，刘继东，四正丁基过硫酸铵氧化裂解2,4 —二硝基苯腙衍生物的反应研究，有机化学，2000, 20(1): 116-121.
[16]陈芬儿，严琼姣，邵兰英，刘明星，D296树脂分散钯催化氢转移反应的研究Ⅰ.取代芳香硝基化合物的还原，离子交换与吸附,1999, 15(6): 572-576.
[17]陈芬儿，李麟，冯秀梅，户业丽，张洪元，严琼姣，dl-萘普生重排合成的工艺研究Ⅵ，中国医药工业杂志，1997, 28(11): 483-486.
授权专利：
[1]李世普, 韩颖超, 闫玉华, 万涛, 王欣宇, 袁琳, 戴红莲, 严琼姣，RGD多肽接枝聚(羟基乙酸-L-赖氨酸-L-乳酸)/ β-磷酸三钙复合材料及其制备方法，中国发明专利，授权专利号：ZL 3.9.
[2]Li Shipu, Han Yingchao, Yan YuHua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao, RGD peptide grafted poly(glycolic acid-L-lysine-L-lactic acid)/β-tricalcium phosphate composite material and preparation method thereof, 美国发明专利，授权专利号： US 7,989,532 B2.
[3]Li Shipu, Han Yingchao, Yan YuHua, Wan Tao, Wang Xinyu, Yuan Lin, Dai Honglian, Yan Qiongjiao, RGD peptide grafted poly(glycolic acid-L-lysine-L-lactic acid)/tricalcium phosphate composite material and preparation method thereof, 欧洲发明专利，授权专利号：EP 2039 377B1.
获奖情况 [1]建筑材料科学技术奖（技术发明类），一等奖，第四完成人，2014年
[2]军队科学技术进步二等奖，第五完成人，2017年