姓名
闵加威（Jia-Wei Min）

民族
汉

职称
副教授

学科专业
生物医学工程

研究方向
神经生物学

电子邮箱
jiawei-min@hotmail.com

简历

博士，副教授，硕士生导师。2016年6月博士毕业于武汉大学，期间从事新生儿的缺血缺氧性脑病及其药物干预研究，发现牡荆素对新生鼠缺氧缺血性脑损伤的神经保护作用。
毕业后前往美国South Dakota University任博士后研究员，从事泛素化蛋白在成年人缺血性脑卒中的功能研究，发现多个靶向ubiquilin-1的药物对成年小鼠缺血性脑损伤的神经保护作用。
2018年5月加盟位于美国University of Texas Health Science Center at Houston，由美国著名脑卒中专家Louise.D. Mccullough 所领导的团队担任高级博士后研究员，从事神经元的再生对成年人缺血性脑卒中保护作用的研究。
近五年发表SCI论文17篇，其中第一作者（含共同第一作者）9篇。现为美国心脏协会(AHA)会员，并多次担任国际著名SCI杂志Stroke; Brain Research Bulletin; Clinical Epidemiology; Neuroreport ; Journal of Molecular Neuroscience 等审稿人。

近年代表性研究成果（限10项以内，含论文、专著、获奖、专利等）

1.Min JW, Bu F, Qi L, Munshi Y, Kim GS, Marrelli SP, McCullough LD, Li J. Inhibition of calcium/calmodulin-dependent protein kinase kinase beta is detrimental in hypoxia(-)ischemia neonatal brain injury. International journal of molecular sciences. 2019;20International journal of Molecular Sciences
2. Yanying Liu*, Min, J.W*, Shelley Feng, Kalpana Subedi and Hongmin Wang (2019)Therapeutic role of a cysteine precursor, OTC, in ischemic stroke is mediated by improved proteostasis in mice.Translational Stroke Research（*co-first author）
3. Min, J.W.,Liu, Y., Wang, D., Qiao, F. & Wang, H. (2018) The non-peptidic delta-opioid receptor agonist Tan-67 mediates neuroprotection post-ischemically and is associated with altered amyloid precursor protein expression, maturation and processing in mice. Journal of neurochemistry, 144, 336-347.
4.Min, J.W., Kong, W.L., Han, S., Bsoul, N., Liu, W.H., He, X.H., Sanchez, R.M. & Peng, B.W. (2017) Vitexin protects against hypoxic-ischemic injury via inhibiting Ca2+/Calmodulin-dependent protein kinase II and apoptosis signaling in the neonatal mouse brain. Oncotarget, 8, 25513-25524.
5.Min, J.W, Lü L, Freeling JL, Martin DS, Wang H. (2017)USP14 inhibitor attenuates cerebral ischemia/reperfusion-induced neuronal injury in mice. Journal of neurochemistry,140, 826-833.
6.Min, J.W., Hu, J.J., He, M., Sanchez, R.M., Huang, W.X., Liu, Y.Q., Bsoul, N.B., Han, S., Yin, J., Liu, W.H., He, X.H. & Peng, B.W. (2015) Vitexin reduces hypoxia-ischemia neonatal brain injury by the inhibition of HIF-1alpha in a rat pup model. Neuropharmacology, 99, 38-50.
7.Min, J.W., Liu, W.H., He, X.H. & Peng, B.W. (2013) Different types of toxins targeting TRPV1 in pain. Toxicon : official journal of the International Society on Toxinology, 71, 66-75.
8.Min, J.W., Peng, B.W., He, X., Zhang, Y. & Li, J.X. (2013) Gender difference in epileptogenic effects of 2-BFI and BU224 in mice. European journal of pharmacology, 718, 81-86.
9. He, M*.,Min, J.W*, Kong, W.L., He, X.H., Li, J.X. & Peng, B.W. (2016) A review on the pharmacological effects of vitexin and isovitexin. Fitoterapia.（*co-first author）