林显光
2015-03-25


姓 名林显光
出生年月日1980.02.27
民 族汉族
职 称副教授
学科专业生物医学工程
研究方向神经生物学
电 话**
电子邮箱**@qq.com
简历（限600字以内。含毕业学校、学历学位、国外经历、社会学术团体兼职、荣誉称号、担任各类专家或学科组成员、研究领域介绍，承担项目、发表论文、专著、获奖、专利情况等）
毕业于华中科技大学生命科院，获生物物理专业博士学位，后在加拿大多伦多大学生理系进行博士后研究。主要领域为细胞分泌，蛋白质相互作用以及离子通道功能与疾病关联方面的研究。 近年来发表多篇高质量论文，阐述了心脏病、糖尿病等相关的一些发病机理和分子机制，为将来彻底攻克这些疾病提供生物学基础。
近年代表性研究成果（限10项以内，含论文、专著、获奖、专利等）
Chao C, Liang T, Kang Y, Lin X, Xie H, Feng ZP, Gaisano HY. Syntaxin-1A inhibits K(ATP) channels by interacting with specific conserved motifs within sulfonylurea receptor 2A. J Mol Cell Cardiol. 2011 Nov;51(5):790-802.(IF5.8)Chang N, Liang T, Lin X, Kang Y, Xie H, Feng ZP, Gaisano HY. Syntaxin-1A interacts with distinct domains within nucleotide-Binding folds of sulfonylurea receptor 1 to inhibit beta-cell KATP channels. J Biol Chem. 2011; May 3; 286(26):23308-18.Xian-Guang LIN, Min ming, Yang Xiao, Yaming Jiu, Maorong Chen, Zheng-Xing Wu and Tao Xu. UNC-31/CAPS docks and primes dense core vesicles in C. elegans neurons. Biochem Biophys Res Commun. 2010; Jul 2;397(3):526-31.Xian-Guang LIN, Recent Advance on Function of CAPS in Vesicular Exocytosis. Progress in Modern Biomedicine, 2010; Vol. 16.Dong Yong-Ming, ZHANG Ming, LIN Xian-Guang, ZHOU Wei, XIE Li, The Mechanism of Calcium Signaling Regulating Insulin Secretion. Progress in Modern Biomedicine, 2008; Vol. 8, No. 5, 937-939.ZHANG Ming, LIN Xian-Guang, JIU Yaming. The Mechanism of Extracellular SST Regulating Secretion of Insulin. JOURNAL OF HUAZHONG NORMAL UNIVERSITY ( Nat. Sci. ), 2008; June, Vol. 42, No.2, 256-261.Hao Zhang, Jie Luo, Jun Xiong, Xian-Guang Lin, Zheng-Xing Wu, Anlian Qu. Zf -and-Hsys-based Cm measurement under the whole-cell patch-clamp recording. Eur J Physiol 2009; 457:1423–1434.Ke-Ming Zhou, Yong-Ming Dong, Qian Ge, Dan Zhu, Wei Zhou, Xian-Guang Lin, Tao Liang, Zheng-Xing Wu, and Tao Xu. PKA Activation Bypasses the Requirement for UNC-31 in the Docking of Dense Core Vesicles from C. elegans Neurons. Neuron. 2007; November 21, 56, 657–669.Jie Liu, Qunfang Wan, Xian-Guang Lin, Hongliang Zhu, Kirill Volynski, Yuri Ushkaryov and Tao Xu. α-Latrotoxin Modulates the Secretory Machinery via Receptor-Mediated Activation of Protein Kinase C. Traffic 2005; 6: 756–765.