甘南琴个人简历：

甘南琴，女，博士生导师，研究员。主要从事蓝藻生物毒素学研究。2002年获武汉大学理学博士学位。2002年到中国科学院水生生物研究所工作。2003年受聘为副研究员。2007-2009在美国乔治城大学（Georgetown University) 医学院作访问学者。2011年获王宽诚优秀女科学家奖励，在加州河滨分校（University of California at Riverside）作访问研究, 同年受聘为中科院水生所研究员。目前在J Biol. Chem., Environ. Microbiol., Water Research, Carcinogenesis, Chem. Res. Toxicol., Toxicol. And Appl. Pharmacol.等国内外期刊发表研究论文40余篇。获得国家授权专利4项。执笔起草国家标准1项（水中微囊藻毒素的测定，GB/T 20466-2006）。



研究领域：1）蓝藻毒素分子毒理学

2）蓝藻毒素生物功能学

3）蓝藻信号传导途径研究
项目资助：

1）微囊藻毒素介导的群体微囊藻细胞间信号传导机制研究（**），国家自然科学基金面上项目

2）微囊藻毒素在微囊藻群体形成中的作用及机制研究（**），国家自然科学基金面上项目

3）生物标记物评价微囊藻毒素新方法研究（**），国家自然科学基金青年基金

4）长江江湖复合生态系统中的主要生物学问题研究，国家自然科学基金优秀重点实验室基金

5）藻毒素快速生物检测技术（2009ZX07527-005），水专项

6）微囊藻胶被形成及群体竞争优势的生理学基础（2008CB418001）， 973
电话：**
电子邮件：gannq@ihb.ac.cn
近年代表文章：

1． Nanqin Gan, Yan Xiao, Lin Zhu, Zhongxing Wu, Jing Liu, Lirong Song, The role of microcystins in maintaining colonies of bloom-forming Microcystis spp.eEnvironmental Microbiology, 14(3): 730-742, 2012.

2． Guofei Dai, Changyun Quan, Xianzheng Zhang, Lirong Song, Nanqin Gan*, Fast removal of cyanobacterial toxin MC-LR by low-cytotoxic microgel-Fe3+ complex，Water Research, 46(5):1482-1489, 2012.

3． Yan Xiao, Nanqin Gan, Jin Liu, Lirong Song, Heterogeneity of buoyancy in response to light between two buoyant types of cyanobacterium Microcystis, Hydrobiol, 679, 297-311, 2012.

4． Yi Ding, Nanqin Gan, Jie Li, Bojan Sedmak, Lirong Song, Hydrogen peroxide induces apoptotic-like cell death in Microcystis aeruginosa (Chroococcales, Cyanobacteria) in a dose-dependent manner, Phycologia, 51 (5), 567–575, 2012.

5． Xiaoyun Sun, Lixin Mi, Lirong Song, Nanqin Gan*, Protection against Microcystin-LR-Induced hepatotoxicity by Sulforaphane in BALB/c mice, Toxicology and applied Pharmacology, 255, 9-17, 2011.

6． Jie Li, Danyun Ou, Lingling Zheng, Nanqin Gan and Lirong Song. Applicability of the fluorescein diacetate assay for metabolic activity measurement of Microcystis aeruginosa (Chroococcales, Cyanobacteria)pPhycological Research, 59: 200–207, 2011.

7． Lixin Mi, Nanqin Gan, Fung-Lung Chung, Isothiocyanates Inhibit Proteasome Activity and Proliferation of Multiple Myeloma Cells. Carcinogenesis, 32 (2):216-23, 2011.

8． Nanqin Gan, Lixin Mi, Xiaoyun Sun, Guofei Dai, Fung-Lung Chung, Lirong Song. Sulforaphane Protects Microcystin-LR-Induced toxicity through Activation of the Nrf2-Mediated Defensive Response. Toxicology and Applied Pharmacology, 247: 129-137, 2010.

9． Nanqin Gan, Mathilde Brunet, Carmen Garrido, Fung-Lung Chung, Lixin Mi，Sulforaphane Activates Heat Shock Response and Enhances Proteasome Activity through Upregulation of Hsp27，J Biol. Chem., 285: 35528-35536, 2010.

10． Nanqin Gan, Sun Xiaoyun, Lirong Song. Activation of Nrf2 by Microcystin-LR and provides advantages for liver cancer cell growth. Chem. Res. Toxicol., 23 (9), 1477–1484, 2010.

11． Nanqin Gan, Qun Huang, Lingling Zheng, Lirong Song, Quantitative assessment of toxic and nontoxic Microcystis colonies in natural environments using fluorescence in situ hybridization and flow cytometry. Science in China (Series C: Life Sciences), 53（8）：973-980, 2010.

12． Lixin Mi, Paul Sirajuddin, Nanqin Gan, Xiantao Wang, A cautionary note on using N-acetylcysteine as an antagonist to assess isothiocyanate-induced reactive oxygen species-mediated apoptosis. Anal. Biochem. 405 (2):269-71, 2010.

13． Lixin Mi, Nanqin Gan, Fung-Lung Chung. Aggresome-like structure induced by isothiocyanates is novel proteasome-dependent degradation machinery. Biochemical and Biophysical Research Communications, 388: 456-462，2009.

14． Lixin Mi, Nanqin Gan, Amrita Cheema, Sivanesan Dakshanamurthy, Xiantao Wang, David C. H. Yang, Fung-Lung Chung. Cancer Preventive Isothiocyanates Induce Selective Degradation of Cellular α- and β-Tubulins by Proteasomes J. Biol. Chem. 284: 17039-17051，2009.

15． Chenlin Hu, Nanqin Gan, Yuanyuan Chen, Lijun Bi, Xianen Zhang, Lirong Song, Detection of microcystins in environmental samples using surface plasmon resonance biosensor. Talanta. 80:407–410，2009.