职称教授
学位博士
邮箱gaojian@mail.hzau.edu.cn
研究方向水产动物营养与生理学-鱼类高度不饱和脂肪酸
合成代谢的调控研究

教育经历
2009/04-2012/01，日本国立鹿儿岛大学，水产学院，博士
2007/04-2009/03，日本国立鹿儿岛大学，水产学院，硕士
2003/04-2007/03，日本国立鹿儿岛大学，水产学院，学士
主要职历
2018/01-至今，华中农业大学，水产学院，教授
2012/11-2017/12，华中农业大学，水产学院，副教授
2012/02-2012/11，日本国立鹿儿岛大学，水产学院，博士后
科研成果
一、承担课题
以项目负责人主持课题（按时间顺序排列）
1.大北农青年****提升专项-饲料亚麻芥油的添加对提高淡水鱼高度不饱和脂肪酸含量的研究，2017.1-2019.12。
2.农业部财政项目-基于精子冻存技术提高圆口铜鱼及长鳍吻跆孵化率及其在增殖放流中的应用研究，2017.1-2017.12。
3.国家自然科学基金面上项目（**）－泥鳅去饱和酶基因（fads）在高度不饱和脂肪酸合成中的作用机制，2017.01-2020.12。
4.农业部财政项目-长鳍吻跆苗种的营养强化研究，2016.01-2016.12。
5.武汉市“黄鹤英才计划”，2016-2018。
6.国家国际科技合作计划-中克（克罗地亚）政府间科技合作项目，（项目编号：7-7），2016-2017。
7.农业部财政项目-圆口铜鱼幼鱼的营养强化及其在人工放流中的应用，2015.01-2015.12。
8.国家自然科学基金青年科学基金项目（**）－不同剂量维生素C对泥鳅肝脏氧化损伤影响的分子机制，2014.01-2016.12。
9.华中农业大学自主科技创新基金（2013PY074）－团头鲂脂类需求及其健康养殖应用研究，2013.01-2015.12。
二、发表论文
第一作者或通讯作者论文（按时间顺序排列）：
*为通讯作者
2018
1.Yun Cui, Xiao Liang, Xiaojuan Cao, Jian Gao*. 2018. Molecular characterization of peroxisome proliferator activated receptor gamma (PPARγ) in loach Misgurnus anguillicaudatus and its potential roles in fatty acid metabolism in vitro. Process Biochemistry. 66. 205-211.
2.Jie Yan, Xiao Liang, Yun Cui, Xiaojuan Cao, Jian Gao*. 2018. Elovl4 can effectively elongate C18 polyunsaturated fatty acids in loach Misgurnus anguillicaudantus. Biochemical and Biophysical Research Communications. 495. 2637-2642.
3.Yang Li, Xiao Liang, Daniel Matulic, M. Hussein, Jian Gao*. 2018. Growth perforamnce, fatty acid composition, lipid deposition and hepatic-lipid metabolism-related gene expression in juvenile pond loach fed diets with different dietary soybean oil levels. Journal of fish biology. 92.1. 17-33.
2017
1.Jie Yan, Xiao Liang, Yin Zhang, Yang Li, Xiaojuan Cao, Jian Gao*. 2017. Cloning of three heat shock protein genes (HSP70, HSP90a and HSP90b) and their expressions in response to thermal stress in loach fed with different levels of vitamin C. Fish and shellfish immunology. 66. 103-111.
2.Jie Yan, Yang Li, Xiao Liang, Yin Zhang, Mahmoud A.O. Dawood, DanileMatuli’c, Jian Gao*. 2017. Effects of dietary protein and lipid levels on growth performance, fatty acid composition and antioxidant related gene expressions in juvenile loach Misgurnus anguillicaudatus. Aquaculture Research. 48.10. 5385-5393.
3.Yin Zhang, Yang Li, Xiao Liang, Xiaojuan Cao, Longfei Huang, Jie Yan, Yanxing Wei, Jian Gao*, 2017. Hepatic transcriptome analysis and identification of differentially expressed genes response to dietary oxidized fish oil in Loach Misgurnus anguillicaudatus, Plos One DOI:10.1371/journal.pone.**.
4.Jie Yan, Chenhui Guo, Mahmoud A.O. Dawood, Jian Gao*. 2017. Effects of dietary chitosan supplementation on the growth, lipid metabolism, immune response and antioxidant-related gene expression in juvenile loach (Misgurnus anguillicaudatus).Beneficial Microbes. 8.3. 439-449.
5.Yan Zhao, Jiaxing Zhao, Yin Zhang, Jian Gao*, 2017. Effects of different dietary vitamin C supplementations on growh performance, mucus immune responses and antioxidant status of loach (Misgurnus anguillicaudatus Cantor) juveniles, Aquaclture Research, 48.8. 4113-4123.
6.Yin Zhang, Yang Li, Xiao Liang, Jian Gao*. 2017. Effects of dietary vitamin E supplementation on growth performance, fatty acid composition, lipid peroxidation and PPAR expressions in juvenile blunt snout bream. Fish Physiology and Biochemistry. 43.4. 913-922.
2016
1.Xiao Liang, Jian Gao*, Dapeng Li, Xiaojuan Cao. 2016. Cloning and expressions of peroxisome proliferator activa te d receptor alpha1 and alpha2 (PPARa1 and PPARa2) in loach (Misgurnusanguillicaudatus) and in response to different dietary fatty acids. Biochemical and Biophysical Research Communications. 481, 38-45.
2.Yongkang Zhang, Tingting He, Yonghui Wen, Lei Pan, Xiaojuan Cao, Weimin Wang, Jian Gao*. 2016. Effects of vitamin E supplementation on growth, lipid peroxidation and fatty acid composition of Dojo loach (Misgurnus anguillicaudatusCantor) fingerlings.Aquaculture Research.47, 1519-1529.
3.高坚,李洋,叶伟钊,王卫民,曹小娟*. 不同脂肪源对泥鳅稚鱼生长性能及脂肪酸组成的影响[J]. 水生生物学报,2016,01:1-9.
4.燕杰,文永辉,王卫民,曹小娟,高坚*.饲料不同蛋白源对泥鳅稚鱼生长性能、体氨基酸组成和抗氧化性能的影响[J]. 华中农业大学学报,2016,03:101-107.
5.Xiao Liang, Yuntong Zhao, Yang Li, Jian Gao*. 2016. Identification and structural characterization of two peroxisome proliferator activated receptors and their transcriptional changes at different developmental stages and after feeding with different fatty acids.Comparative Biochemistry and Physiology, Part B. 9-16.
6.Yang Li, Xiao Liang, Yin Zhang, Jian Gao*.2016.Effects of different dietary soybean oil levels on growth, lipid deposition, tissues fatty acid composition and hepatic lipid metabolism related gene expressions in blunt snout bream (Megalobramaamblycephala) juvenile. Aquaculture, 451, 16-23.
2015
1.Yang Li, Yuntong Zhao, Yongkang Zhang, Xiao Liang, Yin Zhang, Jian Gao*. 2015. Growth performance, fatty acid composition, peroxisome proliferator-activated receptors gene expressions, and antioxidant abilities of blunt snout bream, Megalobrama amblycephala, fingerlings fed different dietary oil sources.Journal of the World Aquaculture Society.46, 395-408.
2.Yang Li, Jian Gao*, Songqian Huang.2015. Effects of different dietary phospholipid levels on growth performance, fatty acid composition, PPAR gene expressions and antioxidant responses of blunt snout breamMegalobrama amblycephalafingerlings. Fish Physiology and Biochemistry. 41:423-436.
3.JianGao*, Shunsuke Koshio. 2015. Effect of dietary lipid oxidation with vitamin C and E supplementation on fillet quality of red sea bream, Pagrus major(Temminck & Schlegel)during storage. Aquaculture research.46(10): 2382-2391.
2014
1.Jian Gao, Shunsuke Koshio, Weimin Wang, Yang Li, Xiongqian Huang, Xiaojuan Cao*.2014. Effects of dietary phospholipids levels on growth performance, fatty acid composition and antioxidant responses of Dojo loachMisgurnus anguillicaudatuslarvae. Aquaculture. 426-427, 304-309
2.Jian Gao*,Shunsuke Koshio, Manabu Ishikawa, Saichiro Yokoyama, Roger Edward P. Mamauag.2014. Interactive effects of vitamin C and E supplementation on growth performance, fatty acid composition and reduction of oxidative stress in juvenile Japanese flounderParalichthys olivaceusfed dietary oxidized fish oil. Aquaculture. 422-423, 84-90.
2013
1.Jian Gao,Shunsuke Koshio*, Manabu Ishikawa, Saichiro Yokoyama, B.T. Nguyen. Roger Edward P. Mamauag. 2013. Effect of dietary oxidized fish oil and vitamin C supplementation on growth performance and reduction of oxidative stress in Red Sea BreamPagrus major. Aquaculture nutrition. 19, 35-44.
2.Jian Gao*, Shunsuke Koshio, Manabu Ishikawa, Saichiro Yokoyama, Daisuke Nose, Tongjun Ren. 2013.Interactive effects of vitamin C and E supplementation on growth, fatty acid composition and lipid peroxidation of sea cucumberApostichopus japonicusfed with dietary oxidized fish oil. Journal of the World Aquaculture Society.44, 536-546.
2012
1.Jian Gao, Shunsuke Koshio, Binh Thanh Nguyen, Weimin Wang, Xiaojuan Cao*.2012. Comparative studies on lipid profiles and amino acid composition of wild and cultured dojo loachMisgurnus anguillicaudatusobtained from Southern Japan. Fisheries Science.78, 1331-1336.
2.Jian Gao, Shunsuke Koshio*, Manabu Ishikawa, Saichiro Yokoyama, Tongjun Ren, Connie Fay Komilus, Yuzhe Han.2012. Effects of dietary palm oil supplements with oxidized and non-oxidized fish oil on growth performances and fatty acid compositions of juvenile Japanese sea bass,Laterolabrax japonicas. Aquaculture. 324-325: 97-103.
3.Jian Gao, Shunsuke Koshio, Manabu Ishikawa*,Saichiro Yokoyama, Md. Abdul Kader and Asda Laining.2012.Interaction between vitamin C and E on oxidative stress in tissues and blood of Red Sea Bream (Pagrus major). Aquaculture Science. 60, 119-126.
4.Jian Gao*. Shunsuke Koshio, Manabu Ishikawa, Saichiro Yokoyama, Roger Edward P. Mamauag, Yuzhe Han. 2012. Effects of dietary oxidized fish oil with vitamin E supplementation on growth performance and reduction of lipid peroxidation in tissues and blood of red sea breamPagrus major. Aquaculture. 356-357. 73-79.
三、发明专利
1.高坚，曹小娟，王卫民，陈钢铭，彭鑫. 一种泥鳅大规格苗种培育池和培育方法. 专利号：8.6
2.高坚，曹小娟. 一种泥鳅仔稚鱼饲料及制备方法. 专利号：4.8
3.高坚，赵运通，梁骁，曹小娟. 一种提高团头鲂肌肉高度不饱和脂肪酸的饲料及制备方法和应用. 专利号：8.1
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