匡汉晖 教授，博士生导师
华中农业大学园艺林学学院蔬菜系，湖北，武汉，430070
联系电话：， Email:kuangfile@mail.hzau.edu.cn


学习经历:
University of Georgia, 佐治亚大学, 1998, 博士
北京林业大学, 1991, 硕士
江西农业大学, 1988, 学士


工作经历:
2008-至今, 博士生导师，华中农业大学
2003-2007,Assistant/Associate Specialist, 加州大学,Berkeley伯克莱分校
1999 – 2003, 博士后，加州大学, Davis戴维斯分校
1998 – 1999, 博士后,University of Haifa,以色列海法大学
1996 – 1997, 访问学生, 新西兰林业研究所
1991 – 1994, 助研, 中国林业科学研究院


研究兴趣：
课题组以莴苣为主要研究对象，同时研究具有与莴苣类似特异器官的甘蓝类和芥菜类蔬菜。主要研究方向蔬菜特异形状的遗传和分子机理。课题包括生菜、芥菜和甘蓝结球性状形成的遗传和分子机理，生菜叶缺刻、大小、叶缘卷曲等叶型形成的遗传和分子机理，茎用蔬菜（莴笋、榨菜、苤蓝）茎大小控制基因的克隆。同时，我们还对莴苣中的花期控制机制、驯化等重要性状感兴趣。我们还与其他课题组合作研究莴苣的代谢基因组学。


学术论文：
1. Chen S., Ren, F., Zhang, L., LiY., Zhang L., Zhu, B., Zeng P., Li Z.,Kuang H. (2018) Unstable allotetraploid tobacco genome due to frequent homeologous recombination, segmental deletion and chromosome loss. Mol Plant 11:914-927.
2. Zhang L., Su W., Tao R., Zhang W., Chen J., Wu P., Jia Y., Larkin R.M., Lavelle D., Truco M.J., Wo S.R.C., Michelmore R.W.,Kuang H.(2017) RNA sequencing provides insights into the evolution of lettuce and the regulation of flavonoid biosynthesis.Nat Commun8(1):2264.
3. Zhou Y, Ma Y, Zeng J, Duan L, Xue X, Wang H, Lin T, Liu Z, Zeng K, Zhong Y, Zhang S, Hu Q, Liu M, Zhang H, Reed J, Moses T, Liu X, Huang P, Qing Z, Liu X, Tu P,Kuang H, Zhang Z, Osbourn A, Ro DK, Shang Y, Huang S. (2016) Convergence and divergence of bitterness biosynthesis and regulation in Cucurbitaceae. Nat Plants. 28;2:16183.
4. Zhang Y, Xia R,Kuang H, Meyers BC. (2016) The diversification of plant NBS-LRR defense genes directs the evolution of microRNAs that target them. Mol Biol Evol. 33(10):2692-705.
5. Yuan, X., Yan, C., Wu, Z., Ren, F., Zhang, H., Baker, B., Chen, J.,Kuang, H. (2015) Frequent gain and loss of resistance against tobacco mosaic virus in Nicotiana species. Mol Plant 8:1813-15.
6. Wei, C.,Kuang, H., Li, F., Chen, J. (2014) The I2 resistance gene homologues in Solanum have complex evolutionary patterns and are targeted by miRNAs. BMC Genomics, 15(1):743.
7. Zhang, Y., Yan, C.,Kuang, H*. (2014) GC-content fluctuation around small RNA-generating sites.FEBS Letters588:764-769.
8. Chen, J., Hu, Q., Zhang, Y., Lu, C.,Kuang, H. (2014) P-MITE: a database for plant miniature inverted-repeat transposable elements.Nucleic Acids Res42(1):D1176-81.
9. Lin, X., Zhang, Y.,Kuang, H.,Chen, J. (2013) Frequent loss of lineages and deficient duplications accounted for low copy number of disease resistance genes in Cucurbitaceae. BMC Genomics 14:335.
10. Jia, J.,…Kuang H(27^thauthor).,…Wang, J., (2013)Aegilops tauschiidraft genome sequence reveals a gene repertoire for wheat adaptation.Nature, 496:91-5.
11. Guo, S.…Kuang, H(31^stauthor),…Xu, Y. et al., (2012) The draft genome of watermelon (Citrullus lanatus) and resequencing of 20 diverse accessions.Nat Genet. 45(1):51-8.
12. Xu, Q.,…Kuang, H.(34^thauthor),…Ruan, Y. (2012) The draft genome of sweet orange (Citrus sinensis).Nat Genet. 16;45(1):59-66.
13. Yin, L.F., Hu, M.J,, Wang, F.,Kuang, H., Zhang, Y., Schnabel, G., Li, G.Q., Luo, C.X. (2012) Frequent gain and loss of introns in fungal cytochrome B genes.PLoS One. 7 (11).
14. Chen, J., Lu, C., Zhang, Y.,Kuang H.(2012) Miniature inverted-repeat transposable elements (MITEs) in rice were originated and amplified predominantly after the divergence of Oryza and Brachypodium and contributed considerable diversity to the species.Mob Genet Elements. 2(3):127-132.
15. Luo, S., Zhang, Y., Hu, Q., Chen, J., Li, Q., Lu, C., Liu, H., Wang, W.,Kuang, H.(2012) Dynamic nucleotide-binding-site and leucine-rich-repeat-encoding genes in the grass family.Plant Physiol, 159:197-210.
16. Lu, C., Chen, J., Zhang, Y., Hu, Q., Su, W.,Kuang，H.(2012) Miniature inverted-repeat transposable elements (MITEs) have been accumulated through amplification bursts and play important roles in gene expression and species diversity inOryza sativa.Mol Bio Evol,29:1005-1017
17.Li G.,Huang S.,Guo X.,Li Y.,Yang Y.,Guo Z.,Kuang H.,Rietman H.,Bergervoet M.,Vleeshouwers V.,van der Vossen EA.,Qu D.,Visser R.,Jacobsen E.,Vossen J. (2011) Cloning and characterization ofR3b; Members of theR3superfamily of late blight resistance genes show sequence and functional divergence.Mol Plant Microbe Interact,24:1132-1142.
18. Xu, X.,…Kuang, H. (31^stauthor),…Visser, RG.（2011）Genome sequence and analysis of the tuber crop potato.Nature475:189–195
19. Luo, S., Peng, J., Li, K., Wang, M.,Kuang, H.（2011）Contrasting evolutionary patterns of theRp1resistance gene family in different species of Poaceae.Mol Bio Evol, 28: 313-325.
20. Kuang, H., Padmanabhan, C., Li, F., Kamei,A., Bhaskar, P. B., Ouyang, S., Jiang, J., Buell, C. R., C. R., and BakerB.(2009) Identification of miniature inverted-repeattransposable elements (MITEs) and biogenesisof their siRNAs in the Solanaceae: New functionalimplications forMITEs.Genome Res,19: 42-56.
21. Kuang, H.,J. van Eck，H., Sicard，D., Michelmore, R. and Nevo, E. (2008) Evolution and genetic population structure of prickly lettuce (Lactuca serriola) and itsRGC2resistance gene cluster.Genetics, 178: 1547-1558.
22. Kuang, H., Caldwell, K., Meyers, B. and Michelmore, R. (2008) Frequent sequence exchanges between Homologs ofRPP8inArabidopsisare not necessarily associated with genomic proximity.Plant J,54: 69-80.
23. Zhang, L., Mojtahedi, H.,Kuang, H.,Baker, B. and Brown, C.R. (2007) The use of STS markers in the marker-assisted selection of Columbia root-knot nematode resistance introgressed fromSolanum bulbocastanum.Crop Sci, 47: 2021-2026.
24. Kuang, H., Ochoa, O., Nevo E., and Michelmore R. (2006) The disease resistance geneDm3is infrequent in natural populations ofLactuca serrioladue to deletions and frequent gene conversions at the RGC2 locus.Plant J, 47: 38-48.
25. Kuang, H.,F. Wei, M. Marano, U. Wirtz, X. Wang, J. Liu, W. Shum,J. Zaborsky, L. J. Tallon, W. Rensink, S. Lobst, P. Zhang, C. Tornqvist, A. Tek, J. Bamberg, J. Helgeson, W. Fry, F. You, M. Luo, J. Jiang, R. C. Buell and B. Baker. (2005) TheR1resistance cluster contains three groups of independently evolving, Type IR1homologues and shows substantial structural variation among haplotypes ofSolanum demissum.Plant J,44: 37-51.
26. Huang, S., van der Vossen, E.A.G,Kuang, H.,Vleeshouwers, V.G.A.A., Zhang, N., Borm, T.J.A., van Eck, H.J., Baker,B., Jacobsen, E. and Visser,R.G.F. (2005)Comparative genomics enabled the isolation of theR3alate blight resistance gene in potato.Plant J, 42: 251-261.
27. Kuang, H.,Woo, S., Meyers, B., Nevo, E., Michelmore, R. (2004) Multiple genetic processes result in heterogeneous rates of evolution within the major cluster disease resistance genes in lettuce.Plant Cell, 16: 2870-2894.
28. Meyers, B., Kozik, A., Griego, A.,Kuang, H.,R.W. Michelmore (2003). Genome-wide analysis of NBS-LRR-encoding genes in Arabidopsis.Plant Cell15: 809-834.
29. Song, J., Bradeen, J.M., Naess, S.K., Raasch, J.A.,Haberlach, G.T., Wielgus S.M.,Liu, J.,Kuang, H., Austin-Phillips, S., Buell, C.B., Helgeson, J.P., and Jiang, J. (2003) Gene RB from Solanum bulbocastanum confers broad spectrum resistance against potato late blight pathogen Phytophthora infestans. Proc Natl Acad Sci USA 100: 9128-9133.
30. Kuang, H., Richardson, T., Carson, P. and Bongarten, B. (1999) Genetic analysis of inbreeding depression inPinus radiataD. Don. II. Genetics of viability genes.Theor Appl Genet99: 140-146.
31. Kuang, H.,Richardson, T., Carson, S., Wilcox, P. and Bongarten, B. (1999) Genetic analysis of inbreeding depression inPinus radiataD. Don. I. Genetic map with distorted markers.Theor Appl Genet98: 697-703.
32. Kuang, H.,Rrchardson, T., Carson, S., and Bongarten, B. (1998) An allele responsible for seeding death inPinus radiataD. Don. Theor Appl Genet96: 640-644.
信息于2018年9月更新