基本信息

姓名:
李国田
出生年月:




性别:
男
硕/博导：
博导


民族:
汉
开设课程：
分子生物学


职称:
教授
研究方向：
水稻-稻瘟菌互作；生物信息学


学位:
博士

联系方式

办公电话：
电子邮件：li4@mail.hzau.edu.cn;leeguotian@163.com

个人简介

李国田，男，华中农业大学教授、博士生导师。长期从事水稻-稻瘟菌互作研究，建立了全基因组测序的水稻快中子突变体库并综合多种生物信息学手段对其中突变进行深度分析；并证明利用此突变体库能够快速克隆水稻抗病相关基因；阐明了稻瘟菌Mst50蛋白在多个MAPK信号通路中的作用。在Plant Cell、Molecular Plant、Environmental Microbiology、Current Opinion in Microbiology和Rice等学术期刊发表研究论文10余篇，
本课题组以水稻和稻瘟菌为研究对象，已从水稻突变体库中筛选出多个抗病突变体，表型突出，正综合利用生物信息学、遗传学、基因组学、CRISPR/Cas9等基因编辑以及生化和分子生物学等技术手段深入研究已鉴定的抗病突变体；在稻瘟菌方面，主要从水稻抗病的角度研究此病原真菌的致病性。本研究室从寄主和病原菌两方面解析水稻与稻瘟菌互作的分子机制，为稻瘟病的防治提供种质资源和理论基础


欢迎热爱生物信息学，水稻以及微生物研究的优秀学生报考本题组研究生！
本课题组计划招博士后2-3名，请将个人材料发至：li4@mail.hzau.edu.cn ！

教育背景
2002.08-2006.07 西北农林科技大学，生物技术， 学士
2006.08-2008.07 西北农林科技大学，植物病理学， 硕士
2008.09-2013.05 普渡大学（美国），植物病理学， 博士


工作经历
2013.07-2018.09 劳伦斯伯克利国家实验室/加州大学戴维斯分校，博士后、助理项目科学家、项目科学家及研究室副主任等职。
2018.09- 至今 华中农业大学植物科学技术学院，教授

科研项目

（1）华中农业大学新进高层次人才科研启动项目，主持
（2）国家自然科学基金：水稻类病斑突变体增强抗病的机理分析， 主持

发明专利及获奖情况

发表的论文及著作

(20). Jiang L^#, Li G^#, Chern M, Jain R, Pham NT, Martin JA, Schackwitz WS, Zhao J, Ruan D, Huang R, Zheng J, Ronald PC (2019). Whole-genome sequencing identifies a rice grain shape mutant, gs9-1. Rice (N Y). 18;12(1):52
(19). Li G, Jones KC, Eudes A, Pidatala VR, Sun J, Xu F, Zhang C, Wei T, Jain R, Birdseye D, Canlas PE, Baidoo EK, Duong PQ, Sharma MK, Singh S, Ruan D, Keasling JD, Mortimer JC, Loqué D, Bartley LE, Scheller HV, Ronald PC (2018) Overexpression of a rice BAHD acyltransferase gene in switchgrass (Panicum virgatum L.) enhances saccharification. BMC Biotechnol 18:54
(18). Zhang X, Liu W, Li Y, Li G and Xu JR (2017) Expression of HopAI interferes with MAP kinase signaling in Magnaporthe oryzae. Environ Microbiol. 19(10):4190-4204
(17). Li G^#, Jain R^#, Chern M^#, Pham NT, Martin JA, Wei T, Schackwitz WS, Lipzen AM, Duong PQ, Jones KC, Ruan D, Barry KW, Schmutz J, Ronald PC (2017) The sequences of 1504 rice mutants facilitate rapid functional genomic studies. Plant Cell 29: 1218-1231 (Plant Cell亮点推荐; F1000Prime推荐文章)
(16). Li G^#, Zhang X^#, Choi YE, Tao AW, Xu JR (2017) MST50 is involved in multiple MAP kinase signaling pathways in Magnaporthe oryzae. Environ Microbiol. 19(5):1959-1974
(15). Yang J, Hsiang T, Bhadauria V, Chen XL, Li G (2017) Plant fungal pathogenesis. BioMed Res Int. 2017: Article ID **
(14). Zhang X, Jain R, Li G* (2016) Roles of Rack1 proteins in fungal pathogenesis. BioMed Res Int. 2016: Article ID **
(13). Li G^#, Chern M^#, Jain R^#, Martin JA, Schackwitz WS, Jiang L, Vega-Sánchez ME, Lipzen AM, Barry KW, Schmutz J, Ronald PC (2016) Genome-wide sequencing of 41 rice (Oryza sativa L.) mutated lines reveals diverse mutations induced by fast-neutron irradiation. Mol Plant. 9: 1078-1081
(12). Wang G, Li G, Zhang S, Jiang C, Qin J, Xu JR (2015) Activation and functional relationship of MoMsb2 with Cbp1 in Magnaporthe oryzae. Environ Microbiol. 17: 2969-81
(11). Yang C, Liu H, Li G, Liu M, Xu JR (2015) The MADS-box transcription FgMcm1 regulates cell identity and fungal development in Fusarium graminearum. Environ Microbiol. 17: 2762-76
(10). Kong LA, Li GT, Liu Y, Liu MG, Zhang SJ, Yang J, Zhou XY, Peng YL, Xu JR (2013) Differences between appressoria formed by germ tubes and appressorium-like structures developed by hyphal tips in Magnaporthe oryzae. Fungal Genet Biol.56:33-41
(9). Li G, Zhou X, Xu JR (2012) Genetic control of infection-related development in Magnaporthe oryzae. Curr Opin Microbiol 15: 678-684
(8). Zhou X, Zhang H, Li G, Shaw B, Xu JR (2012) The Cyclase-associated protein Cap1 is important for proper regulation of infection-related morphogenesis in Magnaporthe oryzae. PLoS Pathog 8: e**
(7). Kong LA, Yang J, Li GT, Qi LL, Zhang YJ, Wang CF, Zhao WS, Xu JR, Peng YL (2012) Different chitin synthase genes are required for various developmental and plant infection processes in the rice blast fungus Magnaporthe oryzae. PLoS Pathog 8: e**
(6). Wang G, Wang C, Hou R, Zhou X, Li G, Zhang S, Xu JR (2012) The AMT1 arginine methyltransferase gene is important for plant infection and normal hyphal growth in Fusarium graminearum. PLoS One 7: e38324
(5). Li G, Zhou X, Kong L, Wang Y, Zhang H, Zhu H, Mitchell TK, Dean RA, Xu JR (2011) MoSfl1 is important for virulence and heat tolerance in Magnaporthe oryzae. PLoS One 6: e19951
(4). Zhang H, Xue C, Kong L, Li G, Xu JR (2011) A Pmk1-interacting gene is involved in appressorium differentiation and plant infection in Magnaporthe oryzae. Eukaryot Cell 10: 1062-1070
(3). Liu W, Zhou X, Li G, Li L, Kong L, Wang C, Zhang H, Xu JR (2011) Multiple plant surface signals are sensed by different mechanisms in the rice blast fungus for appressorium formation. PLoS Pathog 7: e**
(2). Xue XD, Qu ZP, Wang XJ, Zhang YH, Li GT, Huang LL, Kang ZS. Prediction secreted proteins from cDNA library of Puccinia striiformis f. sp. tritici. J. Northwest A&F Univ. (Nat. Sci. Ed.) 37(2):105-111 (in Chinese)
(1). Zhang HY, Li GT, Wang XJ, Duan YH, Xu LS, Guo J, Ma JB, Huang LL, Kang ZS (2009) Cloning and primary characteration analysis of peroxiredoxin gene (TaPrx) from wheat. Sci Agric Sinica 42:1222-1229 (in Chinese)

BOOK CHAPTERS
Zhou X, Li G, Xu JR (2011) Efficient approaches for generating GFP fusion and epitope-tagging constructs in filamentous fungi. Fungal Genomics Methods Mol Biol 722: 199-212