姓　　名:孙丽娟
办公电话: **
电子邮件:lijuansun1212@163.com
通讯地址:湖北省武汉市武昌区友谊大道368号湖北大学生命科学学院
基本情况简介：博士，现任湖北大学讲师、硕士研究生导师
主要社会兼职：无
主要研究领域：细胞药理学、分子药理学


学习和工作简历：
?1999年9月-2003年7月，湖北中医药大学药学系，获理学学士学位
?2003年9月-2006年7月，湖北中医药大学药学系，获理学硕士学位
?2006年9月-2010年3月，华东理工大学药学院，获理学博士学位
?2010年4月-至 今，湖北大学生命科学学院，讲师


承担科研项目情况：
1、武汉市科技局青年晨光计划 (**5): 黄芪抗骨质疏松物质基础及其作用机理的研究, 2011,1-2013,12，主持人.
2、湖北省教育厅优秀中青年人才项目(Q**): 黄芪抗骨质疏松物质基础及其作用机理研究, 2011,1-2013,12，主持人.
3、湖北省自然科学基金(2012FFB00303): Withangulatin A 调节骨代谢作用机理的研究, 2013,1-2015,12，主持人.


代表性论文：
1. Lijuan Sun, Jianwen Liu, Daling Cui, Jiyu Li, Youjun Yu, Lei Ma, Lihong Hu. Anti-inflammatoty of Withagulatin A via COX-2 through MAPK and NF-κB pathways. Journal of cellular biochemistry. 2009, 109(3): 523-541.
2. Lijuan Sun, Jianwen Liu, Lei Ma, Jiyu Li, Youjun Yu, Lihong Hu. Evaluation of immunosuppressive activity of Withangulatin A via ERK/MAPK pathway. Process Biochemistry. 2011, 46: 482-488.
3. Lijuan Sun, Lin Zhou, Jianwen Liu, Mingcang Chen. Amelioration of systemic lupus erythematosus by Withangulatin A in MRL/lpr Mice. Journal of cellular biochemistry. 2011, 112(9): 2376-2382.
4. Lijuan Sun, Youjun Yu, Lihong Hu, Jianwen Liu. Cell-immunosuppressive mechanism of X5 from Withania coagulans. 12th Asia Pacific Confederation of Chemical Engineering Congress, 2008. 08, I-P-026: 0388.
5. Lin Zhou, Lijuan Sun, Hongkun Wua, Lingzhen Zhang, Mingcang Chen, Jianwen Liu, Renqian Zhong. Oridonin ameliorates lupus-like symptoms of MRLlpr/lpr mice by inhibition of B-cell activating factor (BAFF). European Journal of Pharmacology, 2013, In Press.
6. Youjun Yu, Lijuan Sun, Lei Ma, Lihong Hu, Jianwen Liu. Investigation of the immunosuppressive activity of Physalin H on T lymphocytes. International Immunopharmacology. 2010, 10(3), 290-297.
7. Chao-Feng Huang, Lei Ma, Li-Juan Sun, Mumtaz Ali. Immunosuppressive Withanolides from Withania coagulans. Chemistry & Biodiversity. 2009, 6(9): 1415 -1426.
8. Jiyu Li, JunMing Du, Lijuan Sun, Jianwen Liu, Zhiwei Quan. The immuno-suppressive effect of Nordosin via inhibition of IL-2. The American Journal of Chinese Medicine. 2010, 38(1):127-142.
9. Yiyi Ye, Jianwen Liu, Jianhe Xu, Lijuan Sun, Mingcang Chen, Minbo Lan. Nano-SiO2 induces apoptosis via activation of p53 and Bax mediated by oxidative stress in human hepatic cells. Toxicology in Vitro. 2010, 24:751-758.
10. Yiyi Ye, Jianwen Liu, Mingcang Chen, Lijuan Sun, Minbo Lan. In vitro toxicity of silica nanoparticles in myocardial cells. Environmental Toxicology and Pharmacology. 2010.29(2): 131-137.
11. Mingcang Chen, Honggang Gu, Yiyi Ye, Bing Lin, Lijuan Sun, Weiping Deng, Jingzhe Zhang, Jianwen Liu. Protective effects of hesperidin against oxidative stress of tert-butyl hydroperoxide in human hepatocytes. Food and Chemical Toxicology. 2010, 48(10): 2980-2987.


专利：
马磊，刘建文，胡立宏，孙丽娟，于有军, 等. 含Withanolide型化合物的免疫抑制剂ZL**3.0。


获奖：
1、2010年3月 荣获华东理工大学 蒋华良论文一等奖
2、2008年10月 荣获华东理工大学 科研实践综合奖