李冠楠，1985年生，副教授，遗传学专业。主要从事微生物-昆虫宿主互作和遗传毒理学等方面研究。以家蚕为模式生物探究兼性次级共生体对宿主生长发育和营养代谢的作用机理；此外，同时研究有毒物质对家蚕肠内稳态、免疫扰动和血液循环代谢物的损害机制。目前主持和参与的国家级和省部级项目9项。
教育背景及研究经历
2019.05-2020.06，新加坡国立大学，食品科学与技术学院，访问****
2017.05-2020.09，西南大学，畜牧学博士后流动站，特种动物经济饲养方向
2010.09-2015.12，西南大学，生物技术学院，遗传学专业，理学博士（硕博连读）
2005.09-2009.06，西南大学，生命科学学院，生物工程专业，工学学士
代表性研究成果
SCI期刊：
1.Li G.N., Shi M., Zhao S., et al. Toxicity response of silkworm intestine to Bacillus cereus SW7-1 pathogen. Science of the Total Environment. 2019, 692: 1282-1290. (IF2019=6.551；中科院大类二区)
2.Li G.N., Xia X.J., Zhao S., et al. The physiological and toxicological effects of antibiotics on an interspecies insect model. Chemosphere. 2020, 248: 126019. (IF2019=5.778；中科院大类二区)
3.Li G.N., Shi M., Zhao S., et al. RNA-Seq comparative analysis reveals the response mechanism of Enterococcus faecalis TV4 under fluoride exposure. GENE. 2019, 726: 144197. (IF2019=2.984；中科院大类三区)
4.Li G.N., Xia X.J., Zhao H.H., et al. Intestinal microecology associated with fluoride resistance capability of the silkworm (Bombyx mori L.). Applied Microbiology and Biotechnology. 2016, 100(15): 6715-6724. (IF2016=3.420；中科院大类二区)
5.Li G.N., Xia X.J., Zhao H.H., et al. Identification and characterization of Bacillus cereus SW7-1 in Bombyx mori (Lepidoptera: Bombycidae). Journal of Insect Science. 2015, 15(1): 136-140. (IF2015=0.650；中科院大类四区)
6.Xia XJ, Li G.N., Xing Y.X., et al. Antioxidant activity of whole grain highland hull-less barley and its effect on liver protein expression profiles in rats fed with high-fat diets. European Journal of Nutrition, 2017, 57: 2201-2208. (共同一作；IF2017=4.423；中科院大类二区)
7.SENDEGYA P., Li G.N., Zhao H.H., et al. Effect of fluoride on the midgut proteins of T6 and 734 strains of the silkworm (Bombyx mori). Fluoride. 49(2):102-111. (共同一作；IF2015=0.797；中科院大类四区)
8.Xia X.J., Li G.N., Ding Y.B., Ren T.Y., Zheng J., Kan J.Q.* Effect of whole grain Qingke (Tibetan Hordeum vulgare L. Zangqing 320) on serum lipid levels and intestinal microbiota of rats under high-fat diet. Journal of Agricultural and Food Chemistry. 2017, 65(13): 2686–2693. (IF2015= 2.857; 中科院大类一区)
9.Xia XJ, Li G.N., Song JX, et al. Hypocholesterolaemic effect of whole-grain highland hull-less barley in rats fed a high-fat diet. British of Journal Nutrition, 2018, 119: 1102-1110. (IF2017=3.706；中科院大类二区)
10.Xia X.J., Xing Y.X., Li G.N., et al. Antioxidant activity of whole grain Qingke (Tibetan Hordeum vulgare L.) toward oxidative stress in D-galactose induced mouse model. Journal of Functional Foods, 2018, 45: 355-362. (IF=3.47；中科院大类二区)
11.Xia X.J., Li G.N., Zheng J., Ran C.X., Kan J.Q. Biochemical, textural and microstructural changes in whole-soya bean cotyledon sufu during fermentation. International Journal of Food Science and Technology. 2014, 49(8): 1834-1841. (IF2014=1.504；中科院大类二区)
12.Xia X.J., Li G.N., Liao F.R., et al. Granular structure and physicochemical properties of starches from amaranth grain. International Journal of Food Properties. 2015, 18(5): 1029-1037. (IF2015=1.586；中科院大类四区)
13.Xia X.J., Li G.N., Zheng J., et al. Immune activity of sweet potato (Ipomoea batatas L.) glycoprotein after enzymatic and chemical modifications. Food & Function. 2015, 6(6): 2026-202. (IF=2.686；中科院大类一区)
14.Tang W.C., Xiao Y.Y., Li G.N., et al. Analysis of digital gene expression profiling in the gonad of male silkworms (Bombyx mori) under fluoride stress. Ecotoxicology and Environmental Safety, 2018, 153: 127-134. (IF2018=4.527；中科院大类二区)
15.Long Y.H., Li J.R., Zhao T.F., Li G.N., Zhu Y. A new arylalkylamine N-acetyltransferase in silkworm (Bombyx mori) affects integument pigmentation. Applied Biochemistry and Biotechnology. 2015, 175(7): 3447-3457. (IF2015=1.606；中科院大类四区)



2021-01-28 12:18:41