删除或更新信息,请邮件至freekaoyan#163.com(#换成@)

海南医学院导师教师师资介绍简介-杨 溪

/2021-11-24

1.导师的个人情况概括
杨溪,上海交通大学医学院附属第九人民医院口腔颌面-头颈肿瘤科副主任医师、硕导、口腔颌面外科学系秘书。现作为中组部博士团成员,挂职海南西部中心医院副院长。兼任中华口腔医学会口腔颌面-头颈肿瘤专委会工作秘书,曾获得上海市青年拔尖人才、上海市 “医苑新星”等人才计划。主要专业方向为口腔癌的外科治疗及发病机制研究,承担国家自然基金面上项目及青年项目、上海科委自然基金等课题8项,第一及通讯作者发表论文26篇,其中SCI收录24篇。
2.研究方向
口腔癌的临床与基础研究
3.发表的学术论文和专著(第1作者或通讯)
1)Yang X#, Tian X#, Wu K#, Liu W, Li S*, Zhang Z*, Zhang C*. Prognostic impact of perineural invasion in early stage oral tongue squamous cell carcinoma: Results from a prospective randomized trial. Surgical Oncology. 2018; 27:123-128(IF=3.000)
2)S Jin#, X Yang#, Jiayi Li, Wenyi Yang, Hailong Ma*, Zhiyuan Zhang*. p53-targeted lincRNA-p21 acts as a tumor suppressor by inhibiting JAK2/STAT3 signaling pathways in head and neck squamous cell carcinoma[J]. Molecular Cancer, 2019, 18(1):38-56(IF=10.679)
3)Yang X#, Xiao X#, Wu W, Shen X, Zhou Z, Liu W, Shi L*. Cytological study of DNA content and nuclear morphometric analysis for aid in the diagnosis of high-grade dysplasia within oral leukoplakia. Oral Surg Oral Med Oral Pathol Oral Radiol, 2017, 124(3):280-285(IF=1.718)
4)Yang X, Li S, Wu K, Hu L, Liu W, Ji T, Hu Y, Xu L, Sun J, Zhang Z, Zhang C*. Surgical exploration of 71 free flaps in crisis following head and neck reconstruction. Int J Oral Maxillofac Surg. 2016 ;45(2):153-7(IF=1.918)
5)Zhang X, Tian X, Hu Y, Zhang C, Wei C, Yang X*. Oral Peripheral ameloblastoma: A retrospective series study of 25 cases. Med Oral Patol Oral Cir Bucal.2018; 23(3): e277-e281(IF=1.284)
6)Chen F#, Qi S#, Zhang X, Wu J, Yang X*, Wang R*. lncRNA PLAC2 activated by H3K27 acetylation promotes cell proliferation and invasion via the activation of Wnt/β catenin pathway in oral squamous cell carcinoma. International Journal of Oncology. 2019;54:1183-1194(IF=3.571)
7)Chen, F#, Qi, S#, Zhang, X, Wu, J, Yang, X*, Wang, R*.miR-23a-3p suppresses cell proliferation in oral squamous cell carcinomas by targeting FGF2 and correlates with a better prognosis miR-23a-3p inhibits OSCC growth by targeting FGF2.Pathology Research and Practice 2019;215:660-667(IF=1.794)
8)Xiao M#, Liu L#, Zhang S, Yang X*, Wang Y*. Cancer stem cell biomarkers for head and neck squamous cell carcinoma: A bioinformatic analysis. Oncology Reports. 2018; 40: 3843-3851(IF=3.041)
9)Wu K#, Yang X#, Li L, Ruan M, Liu W, Lu W, Zhang C*, Li S*. Neurovascular Invasion and Histological Grade Serve as the Risk Factors of Cervical Lymph Node Metastases in Early Tongue Squamous Cell Carcinoma. Mol Neurobiol.2016;53(5):2920-2926(IF=6.190)
10)C Lou#, X Yang#, L. Hu, Y. Hu, J. S.P. Loh, T Ji, C. Zhang.Oromandibular reconstruction using microvascularized bone flap: report of 1038 cases from a single institution. International Journal of Oral and Maxillofacacial Surgery.2019; 48: 1001–8(IF=1.961)
11)S Liu#, L Shi#, X Yang#, D Ye, T Wang, C Dong, W Guo, Y Liao, H Song, D Xu, J Hu, Z Zhang, J Deng. Nuclear survivin promoted by acetylation is associated with the aggressive phenotype of oral squamous cell carcinoma, Cell Cycle, 2017;16:9, 894-902(IF=3.341)
12)Weiwei Wang, Zhixiao Fang, Xingming Zhang, Haiyan Cai, Yucheng Zhao, Wenli Gu, Xi Yang*, Yingli Wu*. A Self-Assembled Albumin–Conjugate" Nanoprobe for Near Infrared Optical Imaging of Subcutaneous and Metastatic Tumors[J]. ACS Applied Bio Materials, 2020, 3(1):327-334.
13)Xu Q#, Chang H#, Tian X, Lou C, Ma H*, Yang X*. Hypoxia-induced MFAP5 Promotes Tumor Migration and Invasion via AKT Pathway in Head and Neck Squamous Cell Carcinoma. J Cancer. 2020 Jan 14;11(6):1596-1605 (IF=3.182)
14)Liu W, Wang Y, Du G, Zhou Z, Yang X*, Shi L*. Potential association between oral mucosal nevus and melanoma: a preliminary clinicopathologic study. Oral Dis. 2020;26(6):1240-1245 (IF=2.625)
15)Liu W, Zhang Y, Wu L, Yang X*, Shi L*. Characteristics and trends of oral leukoplakia research: A bibliometric study of the 100 most cited articles. Medicine (Baltimore). 2019;98: e16293. (IF=1.87)
16)Liu W, Wu L, Zhang Y, Shi L*, Yang X*. Bibliometric analysis of research trends and characteristics of oral potentially malignant disorders. Clin Oral Investig. 2020;24(1):447–54. (IF=2.453)
17)Feng J, Zhou Z, Shi L, Yang X*, Liu W*. Cancer stem cell markers ALDH1 and Bmi1 expression in oral erythroplakia revisited: implication for driving the process of field cancerization. J Oral Pathol Med. 2020;49(1):96–99. (IF=2.03)
18)Yang X, Shi L, Zhou Z, Liu W*. Podoplanin and ABCG2 expression in oral erythroplakia revisited: Potential evidence for cancer stem cells driving the process of field cancerization. Oral Oncol. 2020; 101:104368. (IF=3.73)
19)Yang X, Liu W*. Bibliometric analysis of the top-cited articles on oral erythroplakia and leukoplakia. J Oral Pathol Med. 2019; 48(6):505-6. (IF=2.03)
20)Xi Yang, Kailiu Wu1, Siyi Li, Longwei Hu, Jing Han, Dongwang Zhu, Xuerui Tian, Wei Liu, Zhen Tian, Laiping Zhong, Ming Yan, Chenping Zhang*, Zhiyuan Zhang*. MFAP5 and TNNC1: Potential markers for predicting occult cervical lymphatic metastasis and prognosis in early stage tongue cancer. Oncotarget.2017;8(2): 2525-2535(IF=5.168)
21)Qiaoshi Xu, Hailong Ma, Hanyue Chang, Zhien Feng, Chenping Zhang*, Xi Yang*. The interaction of interleukin-8 and PTEN inactivation promotes the malignant progression of head and neck squamous cell carcinoma via the STAT3 pathway.Cell Death and Disease. 2020; 11:405(IF=6.130)
22)Tian G, Fu Y, Zhang D, Li J, Zhang Z, Yang X. Identification of four key prognostic genes and three potential drugs in human papillomavirus negative head and neck squamous cell carcinoma.?Cancer Cell Int. 2021;21(1):167
23)Chen FB, Wu P, Zhou R, Yang QX, Zhang X, Wang RR, Qi SC, Yang X. LINC01315 Impairs microRNA-211-Dependent DLG3 Downregulation to Inhibit the Development of Oral Squamous Cell Carcinoma. Front Oncol. 2020;28;10:556084.
24)王健,何优雅,陈一铭,杨溪*,季彤*.172例下颌骨缺损腓骨肌皮瓣修复远期效果评价.中国口腔颌面外科杂志.2019;17(4):337-341
25)高小兰,施琳俊,杨溪.基于《国际口腔科学杂志(英文版)》的口腔医学研究热点分析[J].中国中医药图书情报杂志,2021,45(02):19-23.
26)常涵月,马海龙,杨溪,张志愿.丙酮酸激酶M2与CD276在头颈鳞癌中的表达及临床意义[J].中国口腔颌面外科杂志,2020,18(04):297-301.
27)常涵月,马海龙,杨溪,张志愿.有氧糖酵解在头颈鳞癌中的研究进展[J].临床口腔医学杂志,2020,36(09):569-571.
28)中华口腔医学会口腔颌面修复专业委员会.下颌骨缺损修复重建治疗的专家共识.中华口腔医学杂志.2019:54(7):433-439(执笔人)
4.获得的学术成果奖励(标注名次)
2019年 颌骨缺损功能重建的技术创新与推广应用 国家科技进步二等奖(第十完成人)(2019-J-253-2-01-R10)
2018年 腓骨移植下颌骨缺损修复结合牙种植牵引(DID)技术的临床应用研究 中华口腔医学科技二等奖(第九完成人)(CSA2018020309)

5.获得的发明专利(标注名次)
王伟为 杨溪 吴英理.双靶向化合物、其制备方法及应用.发明专利.2019年5月17日201910411681.3
6.主持过的科研项目(项目名称;项目编号;级别;经费;起止日期)
1)国家自然基金面上项目,82072980,乳酸/lincRNA-p21/PKM2正反馈环路促进TP53突变型口腔鳞癌恶性进展的机制研究,2021/1-2024/12,55万元
2)国家自然科学基金青年项目,81602367,MFAP5通过缺氧微环境诱导的HIF-1ɑ/Notch通路促进口腔鳞癌转移的机制研究,2017/1-2019/12, 17万元
3)上海市科委国内合作项目,21015800800,口腔颌面外科精准医疗与数字医学的示范推广,2021/6-2023/5,40万元
4)上海市自然基金面上项目,20ZR1447300,乳酸通过lincRNA-p21促进TP53突变型口腔鳞癌免疫抑制的机制研究,2020/07-2023/06,20万元
5)上海市自然科学基金青年项目,13ZR1457100,膜联蛋白A1在口腔鳞癌颈部转移淋巴结中的表达及与诱导化疗的关系,2013/10-2016/9,10万元
6)上海市卫健委 202040327基于吲哚氰绿荧光技术提高口腔鳞癌淋巴结隐匿性转移检出率的研究,2021/01-2023/12,10万元
7.获得的学术荣誉
上海市青年拔尖人才
上海交通大学医学院附属第九人民医院 优青培训班
上海市卫生健康委员会医苑新星计划
上海交通大学医学院附属第九人民医院第七届院优秀青年骨干
上海市教委优青青年教师
8.学术兼职
2019/05-至今 中华口腔医学会口腔颌面-头颈肿瘤专委会 青年委员兼工作秘书
2014/07-至今 中华口腔医学会口腔颌面修复专委会 青年委员(第一、二届)
2015/01-至今 上海市口腔医学会口腔颌面-头颈肿瘤专委会 委员兼学术秘书
2020/12-至今 上海市抗癌协会 头颈肿瘤专委会 委员兼秘书
2020/11-至今 中国医促会颅底肿瘤专委会 委员
相关话题/

  • 领限时大额优惠券,享本站正版考研考试资料!
    大额优惠券
    优惠券领取后72小时内有效,10万种最新考研考试考证类电子打印资料任你选。涵盖全国500余所院校考研专业课、200多种职业资格考试、1100多种经典教材,产品类型包含电子书、题库、全套资料以及视频,无论您是考研复习、考证刷题,还是考前冲刺等,不同类型的产品可满足您学习上的不同需求。 ...
    本站小编 Free壹佰分学习网 2022-09-19