廖尚高教授，博士，博士研究生导师，中组部第八批“西部之光”访问****，美国加州大学戴维斯分校访问****，贵州省第十批优秀青年科技人才培养对象，国家药品食品管理局化妆品评审专家，科学出版社十三五规划教材《天然药物化学》副主编；现任贵州医科大学药学院副院长。Analytica Chimica Acta （IF：5.123）、European Journal of Medicinal Chemistry（IF：4.816）等20余个国际SCI杂志审稿专家。
主要研究方向：
中药、民族药的药效物质及其开发应用研究、中药及其他健康产品开发、药物代谢与代谢组学等。
个人简介：
北京师范大学化学系学士（1995）、中国科学院上海药物研究所药物化学博士（2007）。曾师从中科院院士岳建民教授、中国工程院院士张伯礼教授以及代谢组学领域国际知名专家Oliver Fiehn 教授。主持国家自然科学基金3项，以及贵州省优秀青年科技人才专项资金、贵州省人民政府省长基金等10多个项目的研究；参与了民族药与中药开发应用教育部工程研究中心等多个教学科研平台的建设。主讲有《高等天然药物化学》等研究生课程。指导的学生发表SCI论文10余篇，获贵州省优秀硕士论文等奖项。目前已发表论文100余篇（论文被引用1100余次），其中SCI期刊论文50余篇，总影响因子超过150；申请专利26项，已获得专利7项。在化学类顶级期刊Chemical Reviews（最新影响因子52.613），Springer国际出版机构以第一作者身份撰写权威评论各一篇。
主要科研项目：
1. 国家自然科学基金：基于体内直接作用物质的头花蓼治疗泌尿系统感染的物质基础研究（**）（2012-2015），50.00万元。
2. 国家自然科学基金：蓑衣莲酮的保肝作用及其作用机制研究（**）（2013-2016），48万元。
3. 国家自然科学基金：基于黄嘌呤氧化酶抑制作用的金雀花根抗痛风物质基础及其构效关系研究（**）（2019-2022），34万元。
4. 贵州省优秀科技教育人才省长资金：开展苗药头花蓼的抗菌物质基础及作用机理研究，探索构建高效率的药学人才培养模式((黔省专合字(2010)43号) （2010-2012），7万元。
5. 贵州省科技厅社会发展攻关：基于代谢组学技术的膀胱癌多生物标志物的发现及其应用（黔科合SY字[2012]3095号）（2012-2015），12万元。
6. 贵州省优秀青年科技人才培养计划：黔产中药民族药生物活性物质的发现与结构修饰研究（黔科合人字（2015）32号）（2015-2018），18万元。

主要科研教学奖励：
曾获上海市浦东新区第五届优秀科技论文一等奖（2009）、贵州省优秀教师（2014）、贵州省科技成果转化一等奖（2015）、贵州省研究生教学成果奖二等奖等（2017）。

发表的代表性论文和论著（仅列SCI论文和英文论著）：

[1] Meng Zhou, Rui Li, Xiang-Ming Liao, Zheng Wang, Guo-Bo Xu, Zi-Peng Gong, Yuan Lu, Xun He, Yong-Jun Li, Yong-Lin Wang, Lin Zheng, Shang-Gao Liao*. Screening and analysis of potential active components in Shengxiong glucose injection using UHPLC coupled with photodiode array detection and MS/MS. Journal of Separation Science 2018, 41(10): 2130-2138.
[2] Guo-Bo Xu, Yao-Hua Xiao, Qing-Yan Zhang, Meng Zhou, Shang-Gao Liao*. Hepatoprotective natural triterpenoids. European Journal of Medicinal Chemistry 2018, 145: 691-716.
[3] Xiang-Ming Liao, Xun He, Guo-Bo Xu, Zhen Wang, Jing Li, Huan-Yu Guan, Meng Zhou, Yong-Jun Li, Yong-Lin Wang, Li-She Gan, Shang-Gao Liao*. Two Nitrogen-containing Compounds from Pseudostellaria heterophylla. Natural Product Communications 2018, 13(3): 343-346.
[4] Xu Sun, Chengfen Yao, Dandan Xiong, Bao Zhang, Jia Sun, Shanggao Liao, Aimin Wang, Yanyu Lan, Yongjun Li. Simultaneous Quantification of Seven Caffeoylquinic Acids in Ecotypes of Blumea balsamifera at Various Life Stages by High-Performance Liquid Chromatography. Analytical Letters 2018, 51(11): 1642-1653.
[5] Peng Liao, Shi-Qin Hu, Hong Zhang, Liang-Bi Xu, Jing-Zi Liu, Bin He, Shang-Gao Liao, Yong-Jun Li. Study on Anti-Proliferative Activity in Cancer Cells and Preliminary Structure–Activity Relationship of Pseudo-Peptide Chiral Thioureas. Bulletin of the Korean Chemical Society 2018, 39(3): 300-304.
[6] Meng Zhou, Rong-Hong Zhang, Min Wang, Guo-Bo Xu, Shang-Gao Liao*. Prodrugs of triterpenoids and their derivatives. European Journal of Medicinal Chemistry 2017, 131: 222-236.
[7] Meng Zhou, Min Wang, Rui-Feng Zhong, Xiang-Ming Liao, Lian-Li Deng, Guo-Bo Xu, Xun He, Jing Li, Yong-Jun Li, Ting Liu, Yong-Lin Wang, Shang-Gao Liao*. Discovery and structure-activity relationship of auriculatone: A potent hepatoprotective agent against acetaminophen-induced liver injury. Bioorganic & Medicinal Chemistry Letters 2017, 27(16): 3636-3642.
[8] Guo-Bo Xu Min Wang, Jun Liu, Yue-Hao Zhang, Jun-Hong Liu, Jing Li, Meng Zhou, Yao-Hua Xiao, Xun He, Shang-Gao Liao. Buxusoside, a Flavonoid Disaccharide from Buxus sinica. Natural Product Communications 2017, 12(4): 525-526.
[9] Yong Huang, Hui-Yuan Sun, Xiao-Li Qin, Yong-Jun Li, Shang-Gao Liao, Zi-Peng Gong, Yuan Lu, Yong-Lin Wang, Ai-Min Wang, Yan-Yu Lan, Lin Zheng. A UPLC-MS/MS Method for Simultaneous Determination of Free and Total Forms of a Phenolic Acid and Two Flavonoids in Rat Plasma and Its Application to Comparative Pharmacokinetic Studies of Polygonum capitatum Extract in Rats. Molecules 2017, 22(3): 353.
[10] Huan-yu Guan, Peng-fei Li, Xiao-ming Wang, Jia-jing Yue, Yang He, Xiao-mei Luo, Mei-feng Su, Shang-gao Liao, Yue Shi. Shengjiang Xiexin Decoction Alters Pharmacokinetics of Irinotecan by Regulating Metabolic Enzymes and Transporters: A Multi-Target Therapy for Alleviating the Gastrointestinal Toxicity. Frontiers in Pharmacology 2017, 8(769).
[11] Huanyu Guan, Xiaoming Wang, Shiping Wang, Yang He, Jiajing Yue, Shanggao Liao, Yuanda Huang, Yue Shi. Comparative intestinal bacteria-associated pharmacokinetics of 16 components of Shengjiang Xiexin decoction between normal rats and rats with irinotecan hydrochloride (CPT-11)-induced gastrointestinal toxicity in vitro using salting-out sample preparation and LC-MS/MS. RSC Advances 2017, 7(69): 43621-43635.
[12] Dong-Hua Cao, Shang-Gao Liao, Lin Yang, Xiao-Nian Li, Bin Wu, Ping Zhang, Juan Guo, Chun-Fen Xiao, Hua-Bin Hu, You-Kai Xu. Trichiliasinenoids A–C, three 6,7-secomexicanolide limonoids with a 7,29-linkage from Trichilia sinensis. Tetrahedron Letters 2017, 58(33): 3283-3286.
[13] Shang-Gao Liao, Jian-Min Yue, Dimeric Sesquiterpenoids. In Progress in the Chemistry of Organic Natural Products 101, A. D. Kinghorn,H. Falk,S. Gibbons,J. i. Kobayashi, Eds. Springer International Publishing: Cham, 2016; pp 1-112.
[14] Kai-Long Ji, Xiao-Nian Li, Shang-Gao Liao, Hua-Bin Hu, Ren Li, You-Kai Xu. Cytotoxic limonoids from the leaves of Walsura robusta. Phytochemistry Letters 2016, 15: 53-56.
[15] Huan-Yu Guan, Yan Yan, Yong-Lin Wang, Ai-Min Wang, Jun-Hong Liu, Xun He, Yong-Jun Li, Yong Huang, Shang-Gao Liao*. Isolation and characterization of two new 2-isobutylmalates from Bletilla striata. Chinese Journal of Natural Medicines 2016, 14(11): 871-875.
[16] Li Cheng, Kai-long Ji, Shang-gao Liao, Li-she Gan, Lin Yang, Dong-hua Cao, Ying-qian Liu, Juan Guo, Ping Zhang, Chuan-li Lu. Diterpenoids and phenanthrenones from the leaves and stems of Strophioblachia fimbricalyx. Tetrahedron Letters 2016, 57(21): 2262-2265.
[17] Rui-Feng Zhong, Guo-Bo Xu, Zheng Wang, Ai-Min Wang, Huan-Yu Guan, Jing Li, Xun He, Jun-Hong Liu, Meng Zhou, Yong-Jun Li, Yong-Lin Wang, Shang-Gao Liao*. Identification of anti-inflammatory constituents from Kalimeris indica with UHPLC-ESI-Q-TOF-MS/MS and GC-MS. Journal of Ethnopharmacology 2015, 165: 39-45.
[18] Ya-Xin Yang, Ai-Min Wang, Zheng Wang, Yong-Lin Wang, Jin Zhang, Jun-Hong Liu, Xun He, Yong-Jun Li, Xiao-Yan Hao, Shang-Gao Liao*. Chemical Fingerprinting and Multi-marker Determination of the Roots of Indigofera stachyoides by UHPLC-Q-TOF/MS. Current Pharmaceutical Analysis 2015, 11(4): 260-268.
[19] You-Kai Xu, Lin Yang, Shang-Gao Liao, Pei Cao, Bin Wu, Hua-Bin Hu, Juan Guo, Ping Zhang. Koumine, humantenine, and yohimbane alkaloids from Gelsemium elegans. Journal of Natural Products 2015, 78(7): 1511-1517.
[20] Lin Zheng, Yuan Lu, Xu Cao, Yong Huang, Yue Liu, Li Tang, Shang-Gao Liao, Ai-Min Wang, Yong-Jun Li, Yan-Yu Lan, Yong-Lin Wang. Evaluation of the impact of Polygonum capitatum, a traditional Chinese herbal medicine, on rat hepatic cytochrome P450 enzymes by using a cocktail of probe drugs. Journal of Ethnopharmacology 2014, 158 Pt A: 276-82.
[21] Shang-Gao Liao, Zhen Wang, Ya-Yun Wu, Li-Juan Zhang, Jing Li, Ai-Min Wang, Yong-Jun Li, Yan-Yu Lan, Yong-Lin Wang. Structures and hepatocytotoxicity of co-occurring substances in oleanolic acid tablets. Pakistan Journal of Pharmaceutical Sciences 2014, 27(3): 601-605.
[22] Shang-Gao Liao, Zhen Wang, Fa Sun, Li-Juan Zhang, Xun He, Lin Zheng, Ai-Min Wang, Yong-Jun Li, Yong Huang, Yan-Yu Lan, Yong-Lin Wang. Differentiation of Isomeric Polyphenolic Glycosides That Possess Regioisomeric Acylated Monosaccharide Residues by Electrospray Ionization-Tandem Mass Spectrometry. Spectroscopy Letters 2014, 47(1): 19-23.
[23] Kai-Long Ji, Ping Zhang, Hua-Bin Hu, Shuai Hua, Shang-Gao Liao*, You-Kai Xu*. Limonoids from the leaves and twigs of Walsura yunnanensis. Journal of Natural Products 2014, 77(8): 1764-1769.
[24] Kai-Long Ji, Shang-Gao Liao, Xiao-Ling Zheng, Zhi Na, Hua-Bin Hu, Ping Zhang, You-Kai Xu. Limonoids from the fruits of Khaya ivorensis. Molecules 2014, 19(3): 3004-3011, 8 pp.
[25] Mao-Juan Zhang, Bing Liu, Shang-Gao Liao, You-Kai Xu, De-Qiang Feng, Kai-Long Ji, Yan Li. Uncarilic acid and secouncarilic acid, two new triterpenoids from Uncaria sessilifructus. Molecules 2013, 18: 9727-9734.
[26] Zhen Wang, Shang-Gao Liao*, Yan He, Jing Li, Rui-Feng Zhong, Xun He, Ying Liu, Ting-Ting Xiao, Yan-Yu Lan, Qing-De Long, Yong-Lin Wang*. Protective effects of fractions from Pseudostellaria heterophylla against cobalt chloride-induced hypoxic injury in H9c2 cell. Journal of Ethnopharmacology 2013, 147(2): 540-545.
[27] Bing Liu, Lin Yang, You-Kai Xu*, Shang-Gao Liao*, Huai-Rong Luo, Zhi Na. Two new triterpenoids from Gelsemium elegans and Aglaia odorata. Natural Product Communications 2013, 8(10): 1373-1376.
[28] Shang-Gao Liao, Li-Juan Zhang, Fa Sun, Zhen Wang, Xun He, Ai-Min Wang, Yong-Jun Li, Yong Huang, Yan-Yu Lan, Bo-Li Zhang, Yong-Lin Wang. Identification and characterisation of phenolics in Polygonum capitatum by ultrahigh-performance liquid chromatography with photodiode array detection and tandem mass spectrometry. Phytochemical Analysis 2013, 24(6): 556-568.
[29] Shang-Gao Liao, Yue-Ting Li, Li-Juan Zhang, Zhen Wang, Teng-Xiang Chen, Yong Huang, Jing Li, Ai-Min Wang, Yong-Jun Li, Yan-Yu Lan, Yong-Lin Wang. UPLC-PDA-ESI-MS/MS Analysis of Compounds Extracted by Cardiac h9c2 Cell from Polygonum orientale. Phytochemical Analysis 2013, 24(1): 25-35.
[30] You-Kai Xu*, Shang-Gao Liao*, Zhi Na, Hua-Bin Hu, Yan Li, Huai-Rong Luo. Gelsemium alkaloids, immunosuppressive agents from Gelsemium elegans. Fitoterapia 2012, 83(6): 1120-1124.
[31] Ting Tang, Shang-Gao Liao*, Zhi Na, Yan Li, You-Kai Xu*. Dysoxylentin A, the first 21-nortriterpenoid bearing a 2-(propan-2-ylidenyl)furan-3(2H)-one, from Dysoxylum lenticellatum. Tetrahedron Letters 2012, 53(9): 1183-1185.
[32] Shang-Gao Liao, Li-Juan Zhang, Zhen Wang, Fa Sun, Yong-Jun Li, Ai-Min Wang, Yong Huang, Yan-Yu Lan, Yong-Lin Wang. Electrospray ionization and collision-induced dissociation tandem mass spectrometric discrimination of polyphenolic glycosides: exact acylation site determination of the O-acylated monosaccharide residues. Rapid Communications in Mass Spectrometry 2012, 26(21): 2483-2492.
[33] Shang-Gao Liao, Zhen Wang, Jing Li, Ying Liu, Yue-Ting Li, Li-Juan Zhang, Qing-De Long, Yong-Lin Wang. Cytotoxic sesquiterpene lactones from Vernonia bockiana. Chinese Journal of Natural Medicines 2012, 10(3): 230-233.
[34] Feng Zhang, Shang-Gao Liao, Chuan-Rui Zhang, Xiu-Feng He, Wan-Sheng Chen, Jian-Min Yue. Limonoids and diterpenoids from Toona ciliata Roem. var. yunnanensis. Planta Med. 2011, 77(14): 1617-1622.
[35] Sheng-Ping Yang, Hua-Dong Chen, Shang-Gao Liao, Bo-Jun Xie, Ze-Hong Miao, Jian-Min Yue. Aphanamolide A, a New Limonoid from Aphanamixis polystachya. Organic Letters 2011, 13(1): 150-153.
[36] Shang-Gao Liao, Li-Juan Zhang, Fa Sun, Jin-Juan Zhang, A. Ying Chen, Yan-Yu Lan, Yong-Jun Li, Ai-Min Wang, Xun He, Ying Xiong, Li Dong, Xiao-Jun Chen, Yue-Ting Li, Li Zuo, Yong-Lin Wang. Antibacterial and anti-inflammatory effects of extracts and fractions from Polygonum capitatum. Journal of Ethnopharmacology 2011, 134(3): 1006-1009.
[37] Tao Yuan, Rong-Xiu Zhu, Hua Zhang, Oluwatoyin A. Odeku, Sheng-Ping Yang, Shang-Gao Liao, Jian-Min Yue. Structure determination of grandifotane A from Khaya grandifoliola by NMR, X-ray diffraction, and ECD calculation. Organic Letters 2010, 12(2): 252-255.
[38] Yong-Lin Wang, Yong-Jun Li, Ai-Min Wang, Xun He, Shang-Gao Liao, Yan-Yu Lan. Two new phenolic glycosides from Inula cappa. Journal of Asian Natural Products Research 2010, 12(9): 765-769.
[39] Shang-Gao Liao, Li-Juan Zhang, Cui-Bing Li, Yan-Yu Lan, Ai-Min Wang, Yong Huang, Lin Zhen, Xiao-Zhong Fu, Wen Zhou, Xiao-Lan Qi, Zhi-Zhong Guan, Yong-Lin Wang. Rapid screening and identification of caffeic acid and its esters in Erigeron breviscapus by ultra-performance liquid chromatography/tandem mass spectrometry. Rapid Communications in Mass Spectrometry 2010, 24(17): 2533-2541.
[40] Tao Yuan, Sheng-Ping Yang, Hai-Yan Zhang, Shang-Gao Liao, Wei Wang, Yan Wu, Xi-Can Tang, Jian-Min Yue. Phenolic compounds with cell protective activity from the fruits of Livistona chinensis. Journal of Asian Natural Products Research 2009, 11(3): 243-249.
[41] Shang-Gao Liao, Tao Yuan, Chen Zhang, Sheng-Ping Yang, Yan Wu, Jian-Min Yue. Cinnacassides A-E, five geranylphenylacetate glycosides from Cinnamomum cassia. Tetrahedron 2009, 65(4): 883-887.
[42] Shang-Gao Liao, Hua-Dong Chen, Jian-Min Yue. Plant orthoesters. Chemical Reviews 2009, 109(3): 1092-1140.
[43] Jun Huo, Sheng-Ping Yang, Bo-Jun Xie, Shang-Gao Liao, Li-Ping Lin, Jian Ding, Jian-Min Yue. Cytotoxic sesquiterpenoids from Vernonia bockiana. Journal of Asian Natural Products Research 2008, 10(6): 571-575.
[44] Hua-Dong Chen, Sheng-Ping Yang, Shang-Gao Liao, Bo Zhang, Yan Wu, Jian-Min Yue. Limonoids and Sesquiterpenoids from Amoora tsangii. Journal of Natural Products 2008, 71(1): 93-97.
[45] Chuan-Rui Zhang, Sheng-Ping Yang, Qiao Zhu, Shang-Gao Liao, Yan Wu, Jian-Min Yue. Nortriterpenoids from Chukrasia tabularis var. velutina. Journal of Natural Products 2007, 70(10): 1616-1619.
[46] Chuan-Rui Zhang, Sheng-Ping Yang, Shang-Gao Liao, Cheng-Qi Fan, Yan Wu, Jian-Min Yue. Chuktabularins A-D, Four New Limonoids with Unprecedented Carbon Skeletons from the Stem Bark of Chukrasia tabularis. Organic Letters 2007, 9(17): 3383-3386.
[47] Sheng Yin, Xiao-Ning Wang, Cheng-Qi Fan, Shang-Gao Liao, Jian-Min Yue. The First Limonoid Peroxide in the Meliaceae Family: Walsuronoid A from Walsura robusta. Organic Letters 2007, 9(12): 2353-2356.
[48] Sheng-Ping Yang, Chuan-Rui Zhang, Hua-Dong Chen, Shang-Gao Liao, Jian-Min Yue. Sesquiterpenoids from Chloranthus spicatus (Thunb.) Makino. Chinese Journal of Chemistry 2007, 25(12): 1892-1895.
[49] Sheng-Ping Yang, Zhao-Bing Gao, Fang-Dao Wang, Shang-Gao Liao, Hua-Dong Chen, Chuan-Rui Zhang, Guo-Yuan Hu, Jian-Min Yue. Chlorahololides A and B, Two Potent and Selective Blockers of the Potassium Channel Isolated from Chloranthus holostegius. Organic Letters 2007, 9(5): 903-906.
[50] Shang-Gao Liao, Sheng-Ping Yang, Tao Yuan, Chuan-Rui Zhang, Hua-Dong Chen, Yan Wu, You-Kai Xu, Jian-Min Yue. Limonoids from the leaves and stems of Toona ciliata. Journal of Natural Products 2007, 70(8): 1268-1273.
[51] Chuan-Rui Zhang, Sheng-Ping Yang, Shang-Gao Liao, Yan Wu, Jian-Min Yue. Polyoxygenated cyclohexene derivatives from Uvaria rufa. Helvetica Chimica Acta 2006, 89(7): 1408-1416.
[52] You-Kai Xu, Sheng-Ping Yang, Shang-Gao Liao, Hua Zhang, Li-Ping Lin, Jian Ding, Jian-Min Yue. Alkaloids from Gelsemium elegans. Journal of Natural Products 2006, 69(9): 1347-1350.
[53] Shang-Gao Liao, Yan Wu, Jian-Min Yue. Lignans from Wikstroemia hainanensis. Helvetica Chimica Acta 2006, 89(1): 73-80.
[54] Hua-Dong Chen, Sheng-Ping Yang, Shang-Gao Liao, Chuan-Rui Zhang, Jian-Min Yue. Three new 24-noroleanane triterpenoids from Quercus aliena var. acuteserrata. Helvetica Chimica Acta 2006, 89(9): 1971-1977.
[55] Shang-Gao Liao, Bang-Le Zhang, Yan Wu, Jian-Min Yue. New phenolic components from Daphne giraldii. Helvetica Chimica Acta 2005, 88(11): 2873-2878.
[56] Shang-Gao Liao, Zha-Jun Zhan, Sheng-Ping Yang, Jian-Min Yue. Lathyranoic Acid A: First Secolathyrane Diterpenoid in Nature from Euphorbia lathyris. Organic Letters 2005, 7(7): 1379-1382.