联系方式： E-mail: zhouliman88@126.com


简介：
周丽曼，女，山东泰安人，讲师。硕士毕业于中国海洋大学生药学专业，博士毕业于河北大学动物学专业。主要从事药物活性天然产物及药理机制相关研究，通过对多株真菌、放线菌以及多种中药、民族药物进行系统研究，发现并分析了多个化合物的抗菌、抗细菌群体感应活性、抗肿瘤活性，并对它们进行了相关药理机制研究。目前共参与发表SCI论文30余篇，其中第一作者或并列第一作者SCI论文7余篇，包括2篇天然产物顶级期刊（1篇Journal of natural products和1篇Organic letters）。参与国家自然科学基金和省部级基金等共5项，申请和授权发明专利9项

研究领域：
1.主要从天然产物化学研究，主要方向有：微生物天然产物研究、中药与民族药物天然产物研究。
2.从事活性天然产物药理机制研究。


近五年公开发表论文情况：
1. Zhou LM?, Kong FD?, Xie QY, Ma QY, Hu Z, Zhao YX, Luo DQ. Divergolides T-W With Apoptosis-Inducing Activity from the Mangrove-Derived Actinomycete Streptomyces sp. KFD18. Marine Drugs, 2019, 17(4): 219. (IF=3.77，中科院二区).
2. Zhou LM?, Kong FD?, Fan P, Ma QY, Xie QY, Li JH, Zheng HZ, Zheng ZH, Yuan JZ, Dai HF, Luo DQ, Zhao YX. Indole-Diterpenoids with Protein Tyrosine Phosphatase Inhibitory Activities from the Marine-Derived Fungus Penicillium sp. KFD28. Journal of Natural Products, 2019, 82(9):2638-2644. (IF=4.26，中科院二区).
3. Zhang F?, Zhou LM? (co-first), Kong FD, Ma QY, Xie QY, Li JH, Dai HF, Guo L, Zhao, YX. Altertoxins with Quorum Sensing Inhibitory Activities from The Marine-Derived Fungus Cladosporium sp. KFD33. Marine Drugs, 2020, 18(1), 67. (IF=3.77，中科院二区).
4. Kong FD?, Fan P?, Zhou LM? (co-first), Ma QY, Xie QY, Zheng HZ, Zheng ZH, Zhang RS, Yuan JZ, Dai HF, Luo DQ, Zhao YX. Penerpenes A-D, Four Indole Terpenoids with Potent Protein Tyrosine Phosphatase Inhibitory Activity from the Marine-DerivedFungus Penicillium sp. KFD28. Organic Letters, 2019, 21(12): 4864-4867. (IF=6.56，中科院一区，Top 期刊).
5. Kong FD?, Zhou LM? (co-first), Ma QY, Huang SZ, Wang P, Dai HF, Zhao YX. Metabolites with Gram-negative bacteria quorum sensing inhibitory activity from the marine animal endogenic fungus Penicillium sp. SCS-KFD08, Archives of Pharmacal Research, 2017, 40: 25-31. (IF=2.33，中科院三区).
6. Kong FD?, Zhou LM? (co-first), Ma QY, Huang SZ, Wang P, Dai HF, Zhao YX. Penicillars A-E from the marine animal endogenic fungus Penicillium sp. SCS-KFD08. Phytochemistry Letters, 2016, 17: 59-63. (IF=1.418，中科院四区).