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动物遗传育种与繁殖"}],"GH
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广西南宁市大学东路100号
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硕士研究生导师
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学习经历：2000.9-2004.7 广西大学 学士学位；2004.9-2007.7 广西大学 硕士学位；2013.9-2018.12 广西大学 博士学位。工作经历：2007.8-2009.1 中国科学院上海生命科学研究院2009.2至今 广西大学动物科学技术学院
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细胞生物学
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主持的科研项目：1、国家自然科学基金（青年基金）：葡萄糖代谢途径的转换在水牛胚胎干细胞维持自我更新中的作用及其应答机制研究，2020.1-2022.12，在研；2、广西自然科学基金（面上项目）：维生素C通过调控水牛体细胞生物学特性影响转基因克隆效率的机制研究，2017.9-2020.9，在研；3、南宁市科学研究与技术开发计划（重大项目）：澳大利亚安格斯、西门塔尔良种肉牛的引进与健康养殖模式示范推广，2017.1-2020.1，在研；4、广西自然科学基金（青年基金）：水牛类胚胎干细胞表达谱的研究，2012.3-2015.3，已结题。主要参与的科研项目：1、国家自然科学基金（面上项目）：供体细胞葡萄糖代谢途径与水牛体细胞克隆效率的关系及其作用机制研究，2020.1-2023.12，在研；2、国家自然科学基金（面上项目）：不同个体水牛体细胞克隆效率差异的分子机制研究，2017.1-2019.12，在研；3、国家自然科学基金（地区基金）：应用基因捕获高通量测序精准鉴定影响水牛产奶性状的关键基因研究，2019.1-2022.12，在研；4、国家自然科学基金（地区基金）：水牛骨髓间充质干细胞体外培养发生自我转变的机制及低氧对维持其间质细胞特性的调控作用，2017.1-2021.12，在研；5、国家自然科学基金（青年基金）：小分子化合物诱导山羊多能干细胞（CiPSC）的研究，2015.1-2017.12，已结题。6、农业部国家转基因生物新品种培育重大专项，高产奶量转基因水牛新品种培育，2011.8-2012.12，已结题。
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1.Lu F1, Luo C1, Li N1,2, Liu Q, Wei Y, Deng H, Wang X, Li X, Jiang J, Deng Y, Shi D*. Efficient Generation of Transgenic Buffalos (Bubalus bubalis) by Nuclear Transfer of Fetal Fibroblasts Expressing Enhanced Green Fluorescent Protein, Sci Rep. 2018 May 3;8(1):6967. 2.Liu X＃, Luo C＃, Deng K＃, Wu Z, Wei Y, Jiang J, Lu F*, Shi D*.Cytoplasmic volume of recipient oocytes affects the nucleus reprogramming and the developmental competence of HMC buffalo (Bubalus bubalis) embryos, J Vet Med Sci. 2018 Aug 22;80(8):1291-1300.3.Chan Luo＃, Fenghua Lu＃, Xiaoli Wang, Zhiqiang Wang, Xiangping Li, FangqiangGong, Jianrong Jiang, Qingyou Liu, Deshun Shi*. Treatment of donor cells with Trichostatin A improves in vitro development and reprogramming of buffalo (Bubalus bubalis) nucleus transfer embryos, Theriogenology, 2013, 80(8):878-886.4. Z Ruan, X Zhao, X Qin, C Luo, X Liu, Y Deng, P Zhu, Z Li, B Huang, D Shi, F Lu.DNA methylation and expression of imprinted genes are associated with the viability of different sexual cloned buffaloes, Reprod Domest Anim. 2018 Feb;53(1):203-212.5. Sun H, Lu F, Zhu P, Liu X, Tian M, Luo C, Ruan Q, Ruan Z, Liu Q, Jiang J, Wei Y, Shi D*. Effects of Scriptaid on the Histone Acetylation, DNA Methylation and Development of Buffalo Somatic Cell Nuclear Transfer Embryos,Cell Reprogram. 2015 Oct;17(5):404-14.6、Chan Luo1, Fenghua Lu1, Xiaoli Wang, Zhiqiang Wang, Xiangping Li, FangqiangGong, Jianrong Jiang, Qingyou Liu, Deshun Shi*, Treatment of donor cells with Trichostatin A improves in vitro development and reprogramming of buffalo (Bubalus bubalis) nucleus transfer embryos. Theriogenology (IF=2.08), 80(8):878-886, 2013. （co-first author）7、Xiaoxi Zhang, Qingyou Liu, Chan Luo, Yanfei Deng, Kuiqing Cui, Deshun Shi*, Identification and Characterization of Buffalo 7SK and U6 pol III Promoters and Application for Expression of Short Hairpin RNAs. Int J Mol Sci (IF=2.5), 15(2):2596-607, 2014.8、Yanfei Deng, Qingyou Liu, Chan Luo, Shibei Chen, Xiangping Li, Caizhu Wang, Zhenzhen Liu, Xiaocan Lei, Huina Zhang, Hongliang Sun, Fenghua Lu, Jianrong Jiang, Deshun Shi*, Generation of Induced Pluripotent Stem cells From Buffalo (Bubalus bubalis) Fetal Fibroblasts with Buffalo Defined Factors. Stem Cells and Development (IF=4.4), 21(13): 2485-2494, 2012.9、Fenghua Lu1, Chan Luo1, Nan Li1, Yingming Wei, Qingyou Liu, Xiangping Li, Jianrong Jiang, Deshun Shi3, Jiazhou Wei, Zhijian Wei, Generation of transgenic cloned buffalo (Bubalus bubalis) expressing the enhanced green fluorescent protein. Transgenic Research (IF=2.467), 21: 64-64, 2012.（co-first author）10、Sun H, Lu F, Zhu P, Liu X, Tian M, Luo C, Ruan Q, Ruan Z, Liu Q, Jiang J, Wei Y, Shi D, Effects of Scriptaid on the Histone Acetylation, DNA Methylation and Development of Buffalo Somatic Cell Nuclear Transfer Embryos. Cell Reprogram (IF=1.788), 17(5):404-14, 2015.11、Fenghua Lu, Yanping Lao, Hongliang Sun, Chua Lei, Yanfei Deng, Chan Luo, Jianrong Jiang, Deshun Shi, Effects of GSK3 inhibitor on the pluripotency maintenance of buffalo embryonic stem cell-like cells. Reproduction fertility and development, 26 (1):212-212, 2013.12、Fenghua Lu, Jianrong Jiang, Nan Li, Shun Zhang, Hongliang Sun, Chan Luo, Yingming Wei, Deshun Shi, Effects of recipient oocyte age and interval from fusion to activation on development of buffalo (Bubalus bubalis) nuclear transfer embryos derived from fetal firoblast. Theriogenology (IF=2.08), 76: 967-974, 2011.13、Fenghua Lu, Jianrong Jiang, Chan Luo, Qingyou Liu, Yingming Wei, Deshun Shi, Xiangping Li, Hongping Pan, Age of Recipient Oocytes and Activation Time after Fusion of Fetal Fibroblasts in Buffalo (Bubalus bubalis) Nuclear Transfer. Biology of reproduction (IF=4.009), VOL 85, 2011.
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