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韦祖樟
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中共党员
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博士研究生导师, 硕士研究生导师
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韦祖樟, 教授。2008年毕业于中国农业科学院，获博士学位。2008-2013年就职于中国农业科学院上海兽医研究所，从事猪繁殖与呼吸综合征病毒致病机理和标记疫苗的研究。2016-2017年美国宾夕法尼亚大学访问****。2013年-至今在广西大学从事教学、科研工作。主持课题有国家自然科学基金4项，广西自然科学基金2项，广西大学基金项目1项和横向课题1项。作为主要执行人参与国家重点研发、863和欧盟“第七框架”项目等多项课题的研究。发表学术论文40余篇，其中SCI论文20多篇。
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1.广西新发与再发传染病学会副主任委员2.广西畜禽传染病协会副秘书长
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1.本科生课程：动物传染病学2.硕士研究课程：动物免疫学研究进展3.硕士研究生课程：动物微生物学研究进展4.博士研究生课程：人兽共患传染病学5.博士研究生课程：新发动物疫病研究进展
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猪新发与再发传染病遗传变异与致病性研究；猪繁殖与呼吸综合征病毒复制转录机制研究；猪繁殖与呼吸综合征病毒基因工程标记疫苗的研究；
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主持和参与的课题1.主持人：国家自然科学基金面上项目“猪塞内卡病毒毒力上升的分子基础”（**）（2020-2023年）2.主持人：国家自然科学基金地区科学基金项目“猪繁殖与呼吸综合征病毒基因组RNA衣壳化机制的研究”（**）（2017-2020年）3.主持人：国家自然科学基金面上项目“动脉炎病毒细胞嗜性蛋白的鉴定”（**）（2014-2017年）。4.主持人：国家自然科学基金青年科学基金项目“PRRSV程序性-1核糖体移码信号的结构和功能研究”（**）（2010-2012年）。5.主持人：广西自然科学基金项目重点项目”基于PRRSV感染性克隆创制新型疫苗的研究” （2018GXNSFDA281021）（2019-2022年）。6.主持人：广西自然科学基金项目面上项目”猪繁殖与呼吸综合征病毒基因组RNA包装机制的研究” （2016GXNSFAA380159）（2016-2019年）。 7.主持人：广西大学科研基金项目“PRRSV细胞受体结合蛋白的鉴定（XGZ130959）”（2013-2017年）。8.主持人：以马动脉炎病毒为载体的猪繁殖与呼吸综合征疫苗（**）（2016-2018年）9.主要参加人：国家重点研发计划“ 猪病原微生物持续感染的协同发病机制” (2018YFD**)（2018-2020年）。10.主要参加人：863“现代农业技术领域“ 家畜病毒病基因工程疫苗创制”子课题 (2011AA10A208)（2011-2015年）。11.主要参加人：欧盟“第七框架”项目“PoRRSCon-New tools and approaches to control Porcine Reproductive and Respiratory Syndrome (PRRS) in the EU and Asia”--“猪蓝耳病综合防控制剂的创制”（FP7-KBBF-2009-3）（2010-2014年）。
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发表文章1.Emergence and phylogenetic analysis of a Getah virus isolated in southern China. Frontiers in veterinary science. doi.org/10.3389/fvets.2020.552517. Tongwei Ren, Qingrong Mo, Yuxu Wang, Hao Wang, Zuorong Nong, Jinglong Wang, Chenxia Niu, Chang Liu, Ying Chen, Ouyang Kang, Weijian Huang, Zuzhang Wei*. *Corresponding author.2.Generation of a recombinant porcine reproductive and respiratory syndrome virus stably expressing two marker genes. Frontiers in veterinary science. doi: 10.3389/fvets.2020.548282. Hao Wang, Xin Xie, Wei He, Yuxu Wang, Tongwei Ren, Kang Ouyang, Ying Chen, Weijian Huang, Zuzhang Wei*.*Corresponding author.3.Emergence and phylogenetic analysis of a novel Seneca Valley virus strain in the Guangxi Province of China. Research in Veterinary Science 130 (2020) 207–211. Hao Wang, Chenxia Niu, Zuorong Nong, Dongqun Quan, Ying Chen, Ouyang Kang, Weijian Huang, Zuzhang Wei*. *Corresponding author. WOS:0314.Full genomic analysis of new variants of porcine reproductive and respiratory syndrome virus revealed multiple recombination events between different lineages and sublineages. Frontiers in veterinary science. https://doi.org/10.3389/fvets.2020.00603. Jinglong Wang, Siyuan Lin, Dongqun Quan, Hao Wang, Jiabin Huang, Yuxu Wang, Tongwei Ren, Kang Ouyang, Ying Chen, Weijian Huang, Tingrong Luo*, Zuzhang Wei *. *Corresponding author.5.Generation of a porcine reproductive and respiratory syndrome virus expressing a marker gene inserted between ORF4 and ORF5a. Archives of Virology. (2020) 165:1803–1813. Yuxu Wang, Wei He, Qingqing Li, Xin Xie, Nian Qin, Hao Wang, Jiabin Huang, Siyuan Lin, Kang Ouyang,Ying Chen, Weijian Huang, Zuzhang Wei*. *Corresponding author. WOS:0026.Pathogenic Characteristics of a Porcine Astrovirus Strain Isolated in China. Viruses (2019). 11, 1156. Qingli Fang, Cui Wang, Huan Liu, Qingping Wu, Siying Liang, Minli Cen, Qinting Dong, Yingyi Wei, Ying Chen, Kang Ouyang, Zuzhang Wei * and Weijian Huang*. *Corresponding author.7.Genetic analysis of porcine circovirus type 2 (PCV2) strains between 2002 and 2016 reveals PCV2 mutant predominating in porcine population in Guangxi, China. BMC Veterinary Research (2019) 15:118. Jing Yao, Yanran Qin, Yue Zeng, Kang Ouyang, Ying Chen, Zuzhang Wei*,Weijian Huang*. *Corresponding author.8.Genetic analysis of porcine productive and respiratory syndrome virus between 2013 and 2014 in Southern parts of China: identification of several novel strains with amino acid deletions or insertions in nsp2. BMC Veterinary Research (2019) 15:171. Shaofeng Hong, Ying Wei, Siyuan Lin, Jiabing Huang, Wei He, Jing Yao, Ying Chen, Ouyang Kang, Weijian Huang* and Zuzhang Wei* . *Corresponding author.9.Effect of an 88‑amino‑acid deletion in nsp2 of porcine reproductive and respiratory syndrome virus on virus replication and cytokine responses in vitro. Archives of Virology.2018. 2018. 163:1489–1501. Wei He, Ying Wei, Jing Yao, Xin Xie, Jiabin Huang, Siyuan Lin ,Kang Ouyang ,Ying Chen, Weijian Huang*，Zuzhang Wei*. *Corresponding author.10.Construction of a reverse genetic system for porcine astrovirus. Archives of Virology. 2018. 163:1511–1518. Yifeng Qin, Qingli Fang, Huan Liu, Chengyuan Ji,Ying Chen, Kang Ouyang, Zuzhang Wei*, Weijian Huang*. *Corresponding author.11.N-linked Glycosylation of GP5 of Porcine Reproductive and Respiratory Syndrome Virus is Critically Important for Virus Replication in vivo. Journal of virology 2012 Sep;86 (18):9941-51. Zuzhang Wei, Tao Lin, Lichang Sun, Yanhua Li, Xiaoming Wang, Fei Gao, Runxia Liu, Feifei Tan,Jiaqi Lu, Ping Liu, Chunyan Chen, Hongbiao Zhang, Guangzhi Tong*, Shishan Yuan*. 12.Influence of N-linked Glycosylation of Minor Proteins of Porcine Reproductive and Respiratory Syndrome Virus on Infectious Virus Recovery and Receptor Interaction. Virology. 2012 Jul 20;429(1):1-11. Zuzhang Wei, Debin Tian, Lichang Sun, TaoLin, Fei Gao, Yanhua Li, Jiaqi Lu, Ping Liu, Rong Zhang, Chunyan Chen, Runxia Liu, Guangzhi Tong*, Shishan Yuan*. 13.Immunization of pigs with a type 2 modified live PRRSV vaccine prevents the development of a deadly long lasting hyperpyrexia in a challenge study with highly pathogenic PRRSV JX143. Vaccine. 2013 Apr 12;31(16):2062-6. Zuzhang Wei, Jianwu Zhang, Jinshan Zhuang, Zhi Sun,Fei Gao, Shishan Yuan*. 14.Development of a differentiable virus via a spontaneous deletion in the nsp2 region associated with cell adaptation of porcine reproductive and respiratory syndrome virus. Virus research 2013 Jan;171(1):150-60. Xiaomin Wang, Lichang Sun, Yanhua Li, Tao Lin, Fei Gao, Huochun Yao, Kongwang He, Guangzhi Tong*, Zuzhang Wei*, Shishan Yuan. *Corresponding author. 15.Porcine Reproductive and Respiratory Syndrome Virus ORF5a Protein is Essential for Virus Viability. Virus research (2013) Jan;171(1):178-85. Lichang Sun, Yanhua Li, Runxia Liu, Xiaomin Wang, Fei Gao, Tao Lin, Ting Huang, Huochun Yao, Guangzhi Tong, Hongjie Fan*, Zuzhang Wei*, Shishan Yuan. *Corresponding author. 16.High prevalence of torque teno sus virus in China and genetic diversity of the 5' non-coding region. Archives of virology. 2013 Jul;158(7):1567-73. Shao Lun Zhai, Jin Xue Long, Wen Kang Wei , Qin-Ling Chen, ManLin Luo, DianHong Lv, DaCheng Wu, Fei Gao, ShiShan Yuan, GuangZhi Tong, ZuZhang Wei* .*Corresponding author. 17.Genetic manipulation of a transcription-regulating sequence of porcine reproductive and respiratory syndrome virus reveals key nucleotides determining its activity. Archives of virology. 2014 Aug;159(8):1927-40. Haihong Zheng, Keyu Zhang, Xing-Quan Zhu, Changlong Liu, Jiaqi Lu, Fei Gao ,Yan Zhou, Hao Zheng , Tao Lin , Liwei Li ,Guangzhi Tong , Zuzhang Wei* ,Shishan Yuan*. *Corresponding author. 18.Cysteine residues of the Porcine Reproductive and Respiratory Syndrome Virus ORF5a Protein are not essential for virus viability. Virus research 2015 Feb 2;197:17-25. Lichang Sun, Yan Zhou, Runxia Liu, Yanhua Li, Fei Gao, Xiaomin Wang, Hongjie Fan, Shishan Yuan, Zuzhang Wei* ,Guangzhi Tong*. *Corresponding author. 19.Host miR-26a suppresses replication of porcine reproductive and respiratory syndrome virus by upregulating type I interferons Virus research . 2014 Sep 16;195C:86-94. Liwei Li, Zuzhang Wei, Yanjun Zhou, Fei Gao, Yifeng Jiang, Lingxue Yu, Hao Zheng, Wu Tong Shen, Yang Haihong Zheng, Tongling Shan ,Fei Liu, Tianqi Xia, Guangzhi Tong.20.Arterivirus minor envelope proteins are a major determinant of viral tropism in cell culture. Journal of virology. 2012 Apr;86(7):3701-12. Debin Tian, Zuzhang Wei, Jessika C. Zevenhoven-Dobbe, Runxia Liu, Guangzhi Tong, Eric J. Snijder*, Shishan Yuan*.21.Construction of infectious cDNA clones of PRRSV: Separation of coding regions for nonstructural and structural proteins. 2008. ShiShan Yuan, ZuZhang Wei. Sci China Ser C-Life Sci. 51(NO. 2):1-10. 22.Identification of non-essential regions in nucleocapsid protein of porcine reproductive and respiratory syndrome virus for replication in cell culture. Virus Research . 2011 Jun;158(1-2):62-71. FeiFei Tan, Zuzhang Wei, YanhuaLi, Rong Zhang, JinshanZhuang, ZhiSun, ShishanYuan.23.A 5'-proximal Stem-loop Structure of 5' Untranslated Region of Porcine Reproductive and Respiratory Syndrome Virus Genome Is Key for Virus Replication. Virology Journal. 2011, 8:172 . Jiaqi Lu, Fei Gao, Zuzhang Wei, Ping Liu, Changlong Li, Haihong Zheng, Yanhua Li, Tao Lin and Shishan Yuan.24.High prevalence of a novel porcine bocavirus in weanling piglets with respiratory tract symptoms in China. Arch Virol. 2010 Aug;155(8):1313-7. Shaolun Zhai, Cheng Yue, Zuzhang Wei, Jinxue Long, Duoliang Ran, Tao Lin, Yu Deng, Lv Huang, Lichang Sun, Haihong Zheng, Fei Gao, Hao Zheng, Shengnan Chen, Shishan Yuan. 25.Co-existence of multiple strains of porcine circovirus type 2 in the same pig from China. Virology Journal. 2011 Nov 13;8:517. ShaoLun Zhai, ShengNan Chen, Zuzhang Wei ,ShiShan Yuan , WenKang Wei ,JinXue Long. 26.Cis- Acting Structural Element in 5’ UTR Is Essential for Replication of Porcine Reproductive and Respiratory Syndrome Virus. Virus Research, 2012 Jan;163(1):108-19. Fei Gao, Jiaqi Lu, Huochun Yao, Zuzhang Wei, Qian Yang, Shishan Yuan.27.Replacement of the heterologous 5’ untranslated region allows preservation of the fully functional activities of type 2 porcine reproductive and respiratory syndrome virus. Virology. 2013 Apr 25;439(1):1-12. Fei Gao, Huochun Yao, Jiaqi Lu, Zuzhang Wei, Haihong Zhen, Jinshan Zhuang,GuangzhiTong,* Shishan Yuan,*.28.Use of reverse genetics to develop a novel marker porcine reproductive and respiratory syndrome virus. Virus Genes (2012) 45:548–555. Tao Lin, Xiangrui Li, Huochun Yao, Zuzhang Wei, Feifei Tan, Runxia Liu, Lichang Sun, Rong Zhang, Wenliang Li, Jiaqi Lu, Guangzhi Tong, Shishan Yuan.申请专利：1. 韦祖樟，王玉旭，贺微，李清清，谢欣，覃念，王豪，林思远，黄加滨，陈樱，欧阳康，黄伟坚. 猪繁殖与呼吸综合征病毒及其克隆载体和插入基因方法.专利号：1.0.2020年2. 韦祖樟，王豪，谢欣，任同伟，王玉旭，贺微，陈樱，欧阳康，黄伟坚.猪繁殖与呼吸综合征病毒双荧光标记基因重组毒株的构建方法.专利号: 6.X, 2020年、
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