联系方式：
Email：qinsar@glut.edu.cn
一、基本情况
覃礼堂，男，1982年4月出生，博士（后），教授。2008年9月至2011年7月在同济大学环境科学与工程学院环境攻读环境科学专业博士学位，2011年9月至2013年6月在同济大学化学系从事博士后研究工作，2013年7月至今在桂林理工大学从事教学与科研工作，2016-2017年在丹麦哥本哈根大学做访问****。先后主持国家自然科学基金、国家重点研发计划子课题和广西自然科学基金等科研项目10余项，以第一作者和通讯作者在《Science of the Total Environment》、《Environmental Pollution》等国内外刊物上发表SCI收录论文30余篇，申请专利10余项，获得计算机应用软件著作权1项。
二、研究方向
（1）生态与健康风险评估
（2）环境毒理学、计算毒理学
（3）定量结构-活性相关（QSAR）
三、科研项目
国家自然科学基金——基于结构-活性关系的长期低剂量唑类杀菌剂混合物毒性和相互作用定量预测研究（项目批准号**；起止时间2019-2022年）
国家自然科学基金——S-型和J-型浓度-效应关系混合物毒性定量预测研究（项目批准号**；起止时间2015-2017年）
国家重点研发计划，漓江流域喀斯特景观资源可持续利用关键技术研发与示范——子课题“喀斯特水资源生态调控技术集成与优化示范”（项目批准号2019YFC**，2019 -2022）。
自然资源部南方石山地区矿山地质环境修复工程技术创新中心，“矿山生态修复关键技术开发及应用”子课题——尾砂库的重金属分布特征及风险评估在矿山生态修复中的应用（起止时间2020.07-2022.07）
广西自然科学基金——整合生物毒性与化学结构信息预测低剂量农药和PPCPs混合物协同作用（项目批准号2017GXNSFAA198346；起止时间2017-2020年）
广西自然科学基金——农药混合污染物对青海弧菌Q67的联合毒性作用机理（项目批准号2014GXNSFBA118233；起止时间2014-2017年）
桂林市科学技术研究开发项目——桂林市会仙湿地高风险农药复合污染水生态修复技术研究（项目批准号；起止时间2016-2018年）
桂林市科学技术研究开发项目——城市河流湿地中抗生素的污染特征及生态毒性研究（项目批准号**-5，起止时间2019-2021年）
四、主要成果
Litang Qin, Min Liu, Xin Zhang, Lingyun Mo*, Honghu Zeng, Yanpeng Liang. Concentration Addition, Independent Action, and QSAR for Chemical Mixture Toxicities of the Disinfection Byproducts of Haloacetic Acids on the Green Alga Raphidocelis subcapitata. Environmental Toxicology and Chemistry. 2021 (SCI)
刘敏，覃礼堂*，莫凌云，梁延鹏，曾鸿鹄. 4种唑类杀菌剂对蛋白核小球藻的急性毒性及其致毒机理研究. 生态毒理学报，2021
Qiongyuan Nong, Yongan Liu, Litang Qin*, Min Liu, Lingyun Mo, Yanpeng Liang, Honghu Zeng. Toxic mechanism of three azole fungicides and their mixture to green alga Chlorella pyrenoidosa. Chemosphere, 2021, 262: 127793 (SCI)
Lingyun Mo, Yongan Liu, Jie Zhu, Litang Qin*, Yanpeng Liang*, Honghu Zeng. Benefits from hazards, benefits from nothing, and benefits from benefits: the combined effects of five quaternary ammonium compounds to Vibrio qinghaiensis Q67. Environ Sci Eur, 2020, 32, 35. (SCI)
Lingyun Mo, Wen Ma, Song Kong, Litang Qin*, Yanpeng Liang, Junfeng Dai*, Shushen Liu, Study of the Binding Mode of Quaternary ammonium cationic surfactant to firefly luciferase and the prediction of binary mixture toxicity. Chinese Journal of Structural Chemistry. 2020, 39(6): 1167-1177. (SCI)
Litang Qin, Xinrui Pang , Hongru Zeng, Yanpeng Liang*, Lingyun Mo,Dunqiu Wang, Junfeng Dai*. Ecological and human health risk of sulfonamides in surface water and groundwater of Huixian karst wetland in Guilin, China, Science of the Total Environment, 2020, 708:134552. (SCI)
农琼媛, 覃礼堂*, 莫凌云, 刘勇安, 梁延鹏. 抗生素与三唑类杀菌剂混合物对羊角月牙藻的长期毒性相互作用研究. 生态毒理学报, 2019, 14(4): 140-149.
Yuhan Chen, Litang Qin*, Lingyun Mo, Danna Zhao, Honghu Zeng, Yanpeng Liang. Synergetic effects of novel aromatic brominated and chlorinated disinfection byproducts on Vibrio qinghaiensis sp.-Q67. Environmental Pollution, 2019, 250: 375-385. (SCI)
Litang Qin, Xin Zhang, Yuhan Chen, Lingyun Mo*, Honghu Zeng, Yanpeng Liang, Hua Lin*, Dunqiu Wang. Predicting the cytotoxicity of disinfection by-products to Chinese hamster ovary by using linear quantitative structure–activity relationship models. Environmental Science and Pollution Research. 2019, 26(16) 16606–16615. (SCI)
Honghu Zeng, Xin Fu, Yanpeng Liang*, Litang Qin*, Lingyun Mo. Risk assessment of an organochlorine pesticide mixture in the surface waters of Qingshitan Reservoir in Southwest China. RSC Advances, 2018, 8, 17797–17805. (SCI)
Litang Qin, Yuhan Chen, Xin Zhang, Lingyun Mo*, Honghu Zeng, Yanpeng Liang*. QSAR prediction of additive and non-additive mixture toxicities of antibiotics and pesticide. Chemosphere. 2018, 198, 122-129. (SCI)
莫凌云, 梁丽营, 覃礼堂*, 秦萌, 高欢欢. 定性与定量评估4 种重金属及2 种农药混合物对费氏弧菌的毒性相互作用. 生态毒理学报, 2018, 13(1): 251-260.
Lingyun Mo, Danna Zhao, Meng Qin, Litang Qin*, Honghu Zeng, Yanpeng Liang. Joint toxicity of six common heavy metals to Chlorella pyrenoidosa. Environ Sci Pollut Res, 2017, 5: 1-7 (SCI)
Litang Qin, Xin Zhang, Yuhan Chen, Lingyun Mo, Honghu Zeng, Yanpeng Liang. Predictive QSAR models for the toxicity of disinfection byproducts. Molecules, 2017, 22, 1671; doi:10.3390 (SCI)
Lingyun Mo, Litang Qin*, Jie Liu, Honghu Zeng, Yanpeng Liang. Interaction analysis of binary mixtures containing aspirin and oxytetracycline using factorial interaction method. Journal of Environmental Protection and Ecology. 2017, 18(3): 913-921. (SCI)
莫凌云, 覃如琼, 覃礼堂*, 曾鸿鹄, 梁延鹏. 基于分子电性距离矢量预测有机磷杀虫剂的小鼠毒性. 桂林理工大学学报, 2017, 37(2):1-6 (中文核心)
Litang Qin, Xin Zhang, Lingyun Mo, Yanpeng Liang, Honghu Zeng. Further exploring linear concentration addition and independent action for predicting non-interactive mixture toxicity. Chinese J Struct Chem 2017, 36(6): 886-896 (SCI)
Lingyun Mo, Jie Liu*, Litang Qin*, Honghu Zeng, Yanpeng Liang. Two-Stage Prediction on Effects of Mixtures Containing Phenolic Compounds and Heavy Metals on Vibrio qinghaiensis sp. Q67. Bull Environ Contam Toxicol, 2017, 99(1): 17–22. (SCI)
Lingyun Mo, Minyi Zheng, Meng Qin, Xin Zhang, Jie Liu, Litang Qin*, Yanpeng Liang. Quantitative characterization of the toxicities of Cd-Ni and Cd-Cr binary mixtures using combination index method. BioMed Research International, 2016, 2016: 1-6 (SCI)
吴洁, 莫凌云, 覃礼堂*, 曾鸿鹄, 梁延鹏, 覃如琼,朱义年. 部分抗生素对小鼠毒性的QSTR研究. 桂林理工大学学报, 2016, 36(2):349-335 (中文核心)
Lingyun Mo, Ruqiong Qin, Litang Qin*, Honghu Zeng, Yanpeng Liang. Study on the quantitative relationship between the structure and toxicity of organophosphorus pesticide. Chinese J. Struct. Chem. 2015, 34(10): 1473-1478 (SCI)
Litang Qin, Jie Wu, Lingyun Mo, Honghu Zeng*, Yanpeng Liang. Linear regression model for predicting interactive mixture toxicity of pesticide and ionic liquid. Environ Sci Pollut Res, 2015, 22(16): 12759-12768 (SCI)
覃礼堂,刘树深*,莫凌云. 改进的整合加和模型INFCIM及其应用于混合物毒性预测. 中国环境科学, 2014, 34(7): 1890-1896 (EI)
Huanhuan Gao, Litang Qin*, Liangliang Huang, Yanpeng Liang, Lingyun Mo, Honghu Zeng. Progress on the combined effects of PPCP residues in drinking water. Advances in Energy, Environment and Materials Science. 2016, 6: 97-100 (EI)
M. Tang, Honghu Zeng, Litang Qin*. Overview of pesticide toxicity studies on oblique Scenedesmus. Adv. Mater. Res. 2014, 1010-1012: 1220-1224 (EI)
Jie Wu, Lingyun Mo, Litang Qin, Zongqiang Zhu* , Yinian Zhu. Research advancement of the joint toxicity of heavy metals mixture. Adv. Mater. Res. 2014, 522-524: 532 (EI)
曾鸿鹄，覃如琼，莫凌云*，覃礼堂. 有机氯农药对人体健康毒性研究进展. 桂林理工大学学报, 2014, 34(3), 549-553 (中文核心)
M. Tang, H.H. Zeng, L.T. Qin*. Overview of pesticide toxicity studies on oblique Scenedesmus. Adv Mater Res 2014, 1010-1012: 1220-1224. (EI)
覃礼堂, 刘树深*, 肖乾芬, 吴庆生. QSAR模型内部和外部验证方法综述. 环境化学, 2013, 32 (7): 1205-1211. (中文核心)
L.T. Qin, S.S. Liu*, F. Chen, Q.S. Wu. Development of validated quantitative structure–retention relationship models for retention indices of plant essential oils. J Sep Sci 2013, 36(9-10): 1553-1560. (SCI)
L.T. Qin, S.S. Liu, F. Chen, Q.F. Xiao, Q.S. Wu. Chemometric model for predicting retention indices of constituents of essential oils. Chemosphere 2013, 90(2): 300-305. (SCI)
L.T. Qin, S.S. Liu*, J. Zhang, Q.F. Xiao. A novel model integrated concentration addition with independent action for the prediction of toxicity of multi-component mixture. Toxicology 2011, 280(3): 164-172. (SCI)
L.T. Qin, S.S. Liu*, H.L. Liu, Y.H. Zhang. Support vector regression and least squares support vector regression for hormetic dose–response curves fitting. Chemosphere 2010, 78(3): 327-334. (SCI)
L.T. Qin, S.S. Liu*, H.L. Liu. QSPR model for bioconcentration factors of nonpolar organic compounds using molecular electronegativity distance vector descriptors. Mol Divers 2010, 14(1): 67-80. (SCI).
L.T. Qin, S.S. Liu*, H.L. Liu, J. Tong. Comparative multiple quantitative structure-retention relationships modeling of gas chromatographic retention time of essential oils using multiple linear regression, principal component regression, and partial least squares techniques. J Chromatogr A 2009, 1216(27): 5302-5312. (SCI).
L.T. Qin, S.S. Liu*, H.L. Liu, H.L. Ge. A new predictive model for the bioconcentration factors of polychlorinated biphenyls (PCBs) based on the molecular electronegativity distance vector (MEDV). Chemosphere 2008, 70(9): 1577-1587. (SCI)
S.S. Liu*, L.T. Qin, H.L. Liu, D.Q. Yin. Molecular electronegativity distance vector model for the Prediction of bioconcentration factors in fish. J Mol Model 2008, 14(2): 83-92. (SCI)