张云，1982年出生于湖南。博士，教授，硕士研究生导师，广西区****基金获得者，广西青年科技奖获得者。

研究领域：化学与生物传感。E-mail：zy_hnu@163.com；zy@glut.edu.cn。

一、教育与工作经历
2010.07—至今：桂林理工大学，化学与生物工程学院，副教授（2011）、教授（2016）。
2018.11—2019.09：以色列耶路撒冷希伯来大学（The Hebrew University of Jerusalem），化学系，高级访问****。
2014.11—2015.11：英国牛津大学（University of Oxford），化学系，博士后研究员。
2005.09—2010.09：湖南大学，化学生物传感与计量学国家重点实验室，分析化学专业，获理学博士学位。
2001.09—2005.06：湖南大学，化学化工学院，化学专业，获理学学士学位。

二、科研工作
研究领域是化学与生物传感。先后主持各类科研项目11项，其中国家自然科学基金项目3项（面上/地区/青年各1项）、中央引导地方科技发展专项资金项目1项、广西自然科学基金项目3项（****/面上/青年各1项）。已在Anal.Chem.（4篇）、Chem.Commun.（6篇）、Biosens.Bioelectron.（10篇）等国际学术期刊发表SCI收录论文50余篇，其中Nature Index遴选顶级期刊论文10篇、SCI一区TOP期刊论文26篇（含IF﹥10期刊论文10篇）、封面/封底论文5篇、单篇被引超100次论文3篇。参与撰写Elsevier出版英文专著1章。获授权中国发明专利9项。研究成果被Chemistry World、X-MOL、纳米人、搜狐科技等科技媒体专题报道4次。此外，受邀担任Anal.Chem.、Chem.Commun.、Biosens.Bioelectron.、ACS Appl. Mater. Inter.等国际SCI期刊审稿专家。
代表性成果一：在国际上较早开展纸芯片研究，开发出石蜡活字印刷（Anal.Chem.,2014, 86, 2005）、一步绘制（Anal.Chem., 2012, 84,6331）和激光切割（Analyst, 2013, 138,671）等纸芯片制备新方法。这三种方法多次被Angew. Chem. Int. Ed.等顶级期刊论文正面（原图）引用且评述为纸芯片制备代表工作。代表性成果二：提出“二维液相比色分析”新理论（Chem. Commun., 2016, 52, 7454; 2017, 53, 8407），首次获得在液相中实现目标分析物免仪器定量检测的成功范例，丰富和拓展了现有比色分析理论体系。

三、主要获奖与荣誉
2020：桂林理工大学“贤丰优秀人才发展奖”。
2019：第十五届广西青年科技奖；桂林理工大学2017-2018年“科技工作先进个人”、桂林理工大学“优秀青年研究生指导教师”。
2018：广西区****基金；首批桂林理工大学“屏风****（A类）”；被Elsevier出版集团授予SCI一区TOP期刊Biosensors & Bioelectronics的“Outstanding Contribution in Reviewing (杰出审稿贡献奖)”。
2017：中国冶金教育学会优秀硕士学位论文指导教师；首批广西高等学校千名中青年骨干教师培育对象。
2016：桂林理工大学2013-2016年“十佳青年科技工作者”。
2015：广西科学技术奖自然科学二等奖。
2014：第十二届全国电分析化学学术会议论文墙报二等奖。
2011：广西高校化学化工类论文及设计竞赛一等奖。
2008-2010：中国“聚光－分析、测量技术创新奖学金”二等奖；湖南大学（研究生专项）“招商银行奖学金”一等奖；湖南大学“优秀研究生”。

四、代表性学术论著（*通讯作者）
2021
[1] Zihao Deng,? Wenying Jin,? Qiaobo Yin, Jinkun Huang, Ziheng Huang, Haiyan Fu,* Yali Yuan, Jianmei Zou, Jinfang Nie, and Yun Zhang.* Ultrasensitive visual detection of Hg²⁺ ions via the Tyndall effect of gold nanoparticles. Chemical Communications (SCI一区TOP, IF6.16; Nature Index遴选顶级期刊之一), 2021, 57, 2613-2616. 外封底论文.
[2]Mengyuan Yin, Yuqi Wan, Shuai Li, Xiaoting Zhao, Wenwen Zhang, Yun Zhang, Hua Wang.*Carbon nitride-doped melamine-silver adsorbents with peroxidase-like catalysis and visible-light photocatalysis: Colorimetric detection and detoxification removal of total mercury. Journal of Hazardous Materials(SCI一区TOP, IF9.04),2021, 408,124978.
[3]JiameiPu, MingbinLiu, HongboLi,* WeihuaZhao, SuqinWang, YunZhang,* and RuqinYu.*One-Step Enzyme-Free Detection of the miRNA Let-7a via Twin-Stage Signal Amplification. Talanta (SCI二区, IF5.34), Available online 19 February 2021, 122158. Inpress.
[4]Zhourui Xiao,? Han Meng,? Xuefei Qin, Xueqing Sang, Yun Zhang,* and Yali Yuan.*The functionalization of gold nanoparticles as a novel platform for the highly efficient electrochemical detection of silver ions.Analyst(SCI二区, IF3.98), 2021, 146, 597–604

2020
[5]Yuanyuan Cai, Fengxiang Wang, Yue Hua, Huan Liu, Mengyuan Yin, Chunxian Zhang, Yun Zhang,and Hua Wang. A fluorimetric testing strip for the visual evaluation of mercury in blood using copper nanoclusters with DMSO-enhanced fluorescence and stability. Nanoscale(SCI一区TOP, IF6.89), 2020,12, 24079-24084.
[6]Maomao Yao,? Jinkun Huang,? Zihao Deng, Wenying Jin, Yali Yuan, Jinfang Nie,* Hua Wang,* Fuyou Du,and Yun Zhang.*Transforming glucose into fluorescent graphene quantum dots via microwave radiation for sensitive detection of Al3+ ions based on aggregation-induced enhanced emissionAnalyst(SCI二区, IF3.98), 2020, 145, 6981–6986.
[7]Qilin Wen, Xiaolin Liang, Hongcheng Pan, Jianping Li, Yun Zhang, Wenyuan Zhu,* and Zhixiang Long.*Rapid and sensitive electrochemical detection of microRNAs by gold nanoparticle-catalyzed silver enhancement Analyst(SCI二区, IF3.98), 2020, 145, 7893–7897
[8]Luping Feng, Jiani Yang, Sheng Zhang, Lixiang Zhang, Xi Chen, Pan Li, Yuan Gao, Shujing Xie,Yun Zhang,* and Hua Wang. A capillary-based fluorimetric platform for the evaluation of glucose in blood using gold nanoclusters and glucose oxidase in the ZIF-8 matrix.Analyst(SCI二区, IF3.98), 2020, 145, 5273–5279
[9]Yijing Chen,? Lang Zhang,? Jinkun Huang,? Zihao Deng, Yali Yuan,* Jianmei Zou, Jinfang Nie,* and Yun Zhang.*Enhanced functional DNA biosensor for distancebased read-by-eye quantification of various analytes based on starch-hydrolysis-adjusted wettability change in paper devices. RSC Advances, 2020, 10, 28121–28127.

2019
[10]Wencheng Xiao,# Zihao Deng,# Jinkun Huang,# Ziheng Huang, Miaomiao Zhuang, Yali Yuan, Jinfang Nie,* and Yun Zhang.* Highly Sensitive Colorimetric Detection of a Variety of Analytes via the Tyndall Effect. Analytical Chemistry(SCI一区TOP, IF6.35; Nature Index遴选顶级期刊之一), 2019, 91(23), 15114-15122.被纳米人专题报道.
[11]Miaomiao Zhuang,? Yanwen Zhang,? Shaohong Zhou, Yun Zhang, Kemin Wang, Jinfang Nie,* Jianbo Liu.* Uricase-containing coacervate microdroplets as enzyme active membrane-free protocells for detoxification of uric acid in serum. Chemical Communications (SCI一区TOP, IF6.16; Nature Index遴选顶级期刊之一), 2019, 55(92), 13880-13883.
[12]Wencheng Xiao, Yiming Gao, Yun Zhang,* Jiao Li, Zhaoying Liu, Jinfang Nie,* Jianping Li. Enhanced 3D paper-based devices with a personal glucose meter for highly sensitive and portable biosensing of silver ion. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2019, 137, 154-160.
[13]Zhaoying Liu, Wenying Jin,* Fangxiao Wang, Tuanchuan Li, Jinfang Nie,* Wencheng Xiao, Qing Zhang, Yun Zhang.* Ratiometric fluorescent sensing of Pb²⁺and Hg²⁺with two types of carbon dot nanohybrids synthesized from the same biomass. Sensors and Actuators: B. Chemical (SCI一区TOP, IF6.39), 2019,296, 126698.
[14]Haiyan Fu,* Qiaobo Yin, Huili Wang, Jinfang Nie, Wencheng Xiao, Zhaoying Liu, Yijing Chen, Yun Zhang.* Target-triggered in situ autocatalysis in nanopore membrane for point-of-care testing of sub-nanomolar Ag⁺. Sensors and Actuators: B. Chemical (SCI一区TOP, IF6.39), 2019, 287, 290-295.
[15]Xuefei Qin, Yuping Lu, Mengmeng Bian, Yali Yuan*, Yun Zhang.Influence of gold nanoparticles in different aggregation states on the fluorescence of carbon dots and its application, Analytica Chimica Acta(SCI二区, 影响因子5.25),2019, 1091, 119-126.
[16]Jiao Li, Jie Xu, Wenying Jin,Zhongsheng Yi,* Chenbo Cai, Xuefen Huang,Jinfang Nie* and Yun Zhang. Fluorescent kinetics combined with fourth-order calibration for the determination of diclofenac sodium in environmental water. Analytical and Bioanalytical Chemistry, 2019, 411(10), 2019-2029.
[17]边孟孟, 张云, 袁亚利.*基于微流控的电化学生物传感平台研究进展. 分析科学学报, 2019, 35(5), 657-664.

2018
[18]Lang Zhang?, Yali Yuan?, Yun Zhang,* Zhaoying Liu, Wencheng Xiao, Jinfang Nie*, and Jianping Li. Equipment-Free Quantitative Aptamer-Based Colorimetric Assay Based on Target-Mediated Viscosity Change. ACS Omega, 2018, 3(2), 1451-1457.
[19]Jianping Li,*Xionghui Ma, Mengxi Li, Yun Zhang. Does polysaccharide is an idea template selection for glycosyl imprinting?Biosensors and Bioelectronics, (SCI一区TOP, IF10.26), 2018,99,438-442.
[20]Xiaping Zhu, Yali Yuan*, Yun Zhang,Jianping Li,*Hongcheng Pan. Application of different carbon materials for carbon paste electrodes to simultaneous electrochemical detection of four DNA bases with high simpleness. Electroanalysis, 2018, 30, 1723-1733.
[21]王兵月, 乐惠泽, 聂瑾芳,* 肖文成, 刘召应, 张云.* 基于目标介导纳米金凝集的Ag⁺目视检测方法. 化学传感器, 2018, 1, 48-54. 封面论文.

2017
[22]Hui-Li Wang, Yun Zhang,* Rong-Xing Li, Jin-Fang Nie,* Afaf H. El-Sagheer, Tom Brown, Zhao-Ying Liu and Wencheng Xiao. Instrument-free quantitative gold nanoparticle-based liquid-phase colorimetric assays for use in resource-poor environments. Chemical Communications(SCI一区TOP, IF6.16; Nature Index遴选顶级期刊之一), 2017, 53(60), 8407-8410. 外封底论文.
[23]Juanhua Yang, Yun Zhang,*Lang Zhang, Huili Wang, Jinfang Nie,* Zhongxiang Qin, Jiao Li and Wencheng Xiao. Analyte-triggered autocatalytic amplification combined with gold nanoparticle probes for colorimetric detection of heavy-metal ions. Chemical Communications(SCI一区TOP, IF6.16; Nature Index遴选顶级期刊之一), 2017, 53(54), 7477-7480.
[24]Haiyan Fu,*Juanhua Yang, Lin Guo, Jinfang Nie,* Qiaobo Yin, Lang Zhang, Yun Zhang.*Using the Rubik's Cube to directly produce paper analytical devices for quantitative point-of-care aptamer-based assays. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2017, 96, 194-200.
[25]Lang Zhang, Jinfang Nie,* Huili Wang, Juanhua Yang, Bingyue Wang, Yun Zhang* and Jianping Li. Instrument-free quantitative detection of alkaline phosphatase using paper-based devices. Analytical Methods, 2017, 9(22), 3375-3379.
[26]Shangwang Le, Hui Zhou, Jinfang Nie,* Chaohong Cao, Jiani Yang,* Hongcheng Pan, Jianping Li and Yun Zhang.* Fabrication of paper devices via laser-heating-wax-printing for high-tech enzyme-linked immunosorbent assays with low-tech pen-type pH meter readout. Analyst(SCI二区, IF4.01), 2017, 142, 511-516.

2016
[27]Yun Zhang,*Jia-Ni Yang,Jin-Fang Nie,* Juan-Hua Yang,Dong Gao,Lang Zhang, Jian-Ping Li. Enhanced ELISA using a handheld pH meter and enzyme-coated microparticles for the portable, sensitive detection of proteins. Chemical Communications(SCI一区TOP, IF6.16; Nature Index遴选顶级期刊之一), 2016, 52, 3474-3477. 内封底论文; 被X-MOL专题报道.
[28]Jin-Fang Nie, Tom Brown, Yun Zhang.* New two dimensional liquid-phase colorimetric assay based on old iodine–starch complexation for the naked-eye quantitative detection of analytes. Chemical Communications(SCI一区TOP, IF6.16; Nature Index遴选顶级期刊之一), 2016, 52: 7454-7457. 内封底论文; 被X-MOL专题报道.
[29]Yun Zhang,* Dong Gao, Jin-Long Fan, Jin-Fang Nie,* Shang-Wang Le, Wen-Yuan Zhu, Jia-Ni Yang, Jian-Ping Li. Naked-eye quantitative aptamer-based assay on paper device. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2016, 78: 538-546.
[30]Jin-Fang Nie,* Bo Li, Yun Zhang,* Jin-Long Fan, Zhong-Sheng Yi, Zhi-Rong Cai. High-order calibration for the spectrofluorimetric determination of pesticides based on photochemical derivatization. A solution of the problems of inner-filter effects and matrix interferences in complex environmental water. Chemometrics and Intelligent Laboratory Systems, 2016, 156: 36-53.

2015
[31]Yun Zhang,* Jin-Long Fan, Jin-Fang Nie,* Shang-Wang Le, Wen-Yuan Zhu, Dong Gao, Jia-Ni Yang, Song-Bai Zhang, Jian-Ping Li. Timing readout in paper device for quantitative point-of-use hemin/G-quadruplex DNAzyme-based bioassays. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2015, 73: 13-18.
[32]Jian-Ping Li,* Lian-Ming Zhang, Ge Wei, Yun Zhang, Ying Zeng. Highly sensitive and doubly orientated selective molecularly imprinted electrochemical sensor for Cu²⁺. Biosensor and Bioelectronics(SCI一区TOP, IF10.26), 2015, 69: 316-320.
[33]Jianping Li,* Mi Sun, Xiaoping Wei, Lieping Zhang, Yun Zhang. An electrochemical aptamer biosensor based on “gate-controlled” effect using β-cyclodextrin for ultra-sensitive detection of trace mercury. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2015, 74: 423-426.

2014
[34]Yun Zhang,* Cai-Bin Zhou, Jin-Fang Nie,* Shang-Wang Le, Qun Qin, Fang Liu, Yu-Ping Li, Jian-Ping Li. Equipment-free quantitative measurement for microfluidic paper-based analytical devices fabricated using the principles of movable-type printing. Analytical Chemistry(SCI一区TOP, IF6.35; Nature Index遴选顶级期刊之一),2014, 86(4): 2005-2012.
[35]Yun Zhang,* Fang Liu, Jin-Fang Nie,* Fu-Yang Jiang, Cai-Bin Zhou, Jia-Ni Yang, Jin-Long Fan, Jian-Ping Li. An electrochemical sensing platform based on local repression of electrolyte diffusion for single-step, reagentless, sensitive detection of a sequencespecific DNA-binding protein. Analyst(SCI二区, IF4.01), 2014, 139(9): 193-2198.
[36]Jian-Ping Li,* Yi-Juan Shao, Wei-Ling Yin, Yun Zhang. A strategy for improving the sensitivity of molecularly imprinted electrochemical sensors based on catalytic copper deposition. Analytica Chimica Acta(SCI二区, IF5.25), 2014, 817: 17-22.

2013
[37]Jin-Fang Nie, Yuan-Zhi Liang, Yun Zhang,* Shang-Wang Le, Dun-Nan Li, Song-Bai Zhang.* One-step patterning of hollow microstructures in paper by laser cutting to create microfluidic analytical devices.Analyst(SCI二区, IF4,01), 2013, 138(2): 671-676.
[38]Jian-Ping Li,* Qian Xu, Cong Fu, Yun Zhang. A dramatically enhanced electrochemiluminescence assay for CA125 based on dendrimer multiply labeled luminol on Fe3O4 nanoparticles. Sensors and Actuators B-Chemical(SCI一区TOP, IF6,39). 2013, 185: 146-153.

2012
[39]Jin-Fang Nie, Yun Zhang,* Li-Wen Lin, Cai-Bin Zhou, Shu-Huai Li, Lian-Ming Zhang, Jian-Ping Li. Low-cost fabrication of paper-based microfluidic devices by one-step plotting. Analytical Chemistry(SCI一区TOP, IF6.35; Nature Index遴选顶级期刊之一),2012, 84(15): 6331-6335.
[40]Jian-Ping Li,* Yu-Ping Li, Yun Zhang, Ge Wei. Highly sensitive molecularly imprinted electrochemical sensor based on the double amplification by an inorganic Prussian blue catalytic polymer and the enzymatic effect of glucose oxidase. Analytical Chemistry, 2012(SCI一区TOP, IF6.35; Nature Index遴选顶级期刊之一), 84(4): 1888-1893.
[41]Jin-Fang Nie, Yun Zhang,* Hua Wang, Shi-Ping Wang, Guo-Li Shen.* Superhydrophobic surface-based magnetic electrochemical immunoassay for detection of Schistosoma japonicum antibodies. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2012, 33(1): 23-28.
[42]Jin-Fang Nie, Yun Zhang,?Zhong-Sheng Yi, Hong-Yan Zou, Hai-Yan Fu, Hai-Long Wu. Advanced chemometric algorithm coupled to subspace projection technique between original and pseudo samples: A snapshot of chemical rank estimation for high-order data. Chemometrics and Intelligent Laboratory Systems, 2012, 118: 211-218.
[43]Jian-Ping Li, Ge Wei, Yun Zhang. Chapter 2 - Molecularly imprinted polymers as recognition elements in sensors.In: Song-Jun Li, Yi Ge, Sergey A. Piletsky, Joseph Lunec (Ed.). Molecularly Imprinted Sensors, Elsevier Press, Amsterdam, 2012, 35-55.

2006-2011
[44]Yun Zhang, Hua Wang,* Jian-Ping Li, Jin-Fang Nie, Yu-Wei Zhang, Guo-Li Shen,* Ru-Qin Yu. Nitrocellulose strip array assembled on superhydrophobic surface: An aqueous solution diffusion-localized platform for multianalyte immunogold staining assays. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2011, 26 (7): 3272-3277.
[45]Guang-Yu Shen, Yun Zhang. Highly sensitive electrochemical stripping detection of hepatitis B surface antigen based on copper-enhanced gold nanoparticle tags and magnetic nanoparticles. Analytica Chimica Acta(SCI二区, IF5.25), 2010, 674(1): 27-31.
[46]Sui-Ping Wang, Yong Lei, Yun Zhang, Jian Tang, Guo-Li Shen,* Ru-Qin Yu. Hydroxyapatite nanoarray-based cyanide biosensor. Analytical Biochemistry, 2010, 398(2): 191-197.
[47]Yun Zhang, Hua Wang,* Jin-Fang Nie, Yu-Wei Zhang, Guo-Li Shen,* Ru-Qin Yu. Individually addressable microelectrode arrays fabricated with gold-coated pencil graphite particles for multiplexed and high sensitive impedance immunoassays. Biosensors and Bioelectronics(SCI一区TOP, IF10.26), 2009, 25(1): 34-40.
[48]Yun Zhang, Hua Wang,* Jin-Fang Nie, Hui Zhou, Guo-Li Shen,* Ru-Qin Yu. Mussel-inspired fabrication of encoded polymer films for electrochemical identification. Electrochemistry Communications(SCI二区, IF4.19), 2009, 11(10): 1936-1939.
[49]Yu-Wei Zhang, Yun Zhang, Hua Wang,* Ba-Ni Yan, Guo-Li Shen, Ru-Qin Yu. An enzyme immobilization platform for biosensor designs of direct electrochemistry using flower-like ZnO crystals and nano-sized gold particles. Journal of Electroanalytical Chemistry, 2009, 627(1-2): 9-14.
[50]Yun Zhang, Hua Wang,* Ba-Ni Yan, Yu-Wei Zhang, Ping Yin, Guo-Li Shen,* Ru-Qin Yu. A rapid and efficient strategy for creating super-hydrophobic coatings on various material substrates. Journal of Materials Chemistry(SCI一区TOP, IF6.26), 2008, 18(37): 4442-4449. 被Chemistry World专题报道.
[51]Yun Zhang, Hua Wang,* Ba-Ni Yan, Yu-Wei Zhang, Ji-Shan Li, Guo-Li Shen,* Ru-Qin Yu. A reusable piezoelectric immunosensor using antibody-adsorbed magnetic nanocomposite. Journal of Immunological Methods, 2008, 332(1-2): 103-111.
[52]Jin-Fang Nie, Hai-Long Wu,* Xue-Mei Wang, Yun Zhang, Shao-Hua Zhu, Ru-Qin Yu. Determination of testosterone propionate in cosmetics using excitation-emission matrix fluorescence based on oxidation derivatization with the aid of second-order calibration methods. Analytica Chimica Acta(SCI二区, IF5.25), 2008, 628(1): 24-32.
[53]Hui Feng, Hua Wang,* Yun Zhang, Ba-Ni Yan, Guo-Li Shen, Ru-Qin Yu. A direct electrochemical biosensing platform constructed by incorporating carbon nanotubes and gold nanoparticles onto redox poly(thionine) film. Analytical Science, 2007, 23(2): 235-239.
[54]Hua Wang,*Yun Zhang, Ba-Ni Yan, Li Liu, Shi-Ping Wang, Guo-Li Shen, Ru-Qin Yu. Rapid, simple, and sensitive immunoagglutination assay with SiO₂particles and quartz crystal microbalance for quantifying Schistosoma japonicum antibodies. Clinical Chemistry(SCI一区TOP, IF8.64), 2006, 52(11): 2065-2071.