张芳芳，副教授，硕士生导师，兰州大学基础医学院病理学研究所
Fangfang Zhang, Associate Professor, Institute of Pathology, School of Basic Medical Sciences, Lanzhou University
E-mail: zhangff@lzu.edu.cn
科研方向
1.COPD的发病机制与干预治疗
2.肿瘤发病机制与免疫治疗
Research Interest
1.Pathogenesis and therapy of COPD.
2.Pathogenesis and immune therapy of cancer.
个人简介
2007年毕业于中国科学院大学；2008年至2011年于美国路易斯安娜州立大学健康医学中心从事博士后研究工作，研究方向为肿瘤发病机理；2012年至2016年在美国纽约石溪大学从事肺纤维化治疗干预博士后研究工作。2016年3月加入兰州大学基础医学院病理学研究所。欢迎有志于从事COPD和肿瘤学研究的同学加入本课题组。研究背景不限于医学专业。

Resume
Postdoc: Stony Brook University, Department of Pathology
Postdoc: Louisiana State University, Health Sciences Center, Department of Microbiology and Immunology
Ph. D.: Institute of Zoology, Chinese Academy of Sciences

发表论文
Publications
1.F Zhang,Z Jiang, A Xu, Y Zeng, C Li. Recent geological events and intrinsic behavior influence the population genetic structure of the chiru and Tibetan gazelle on the Tibet Plateau. PLos One, 2013. 04. 24, 8(4):e60712.
2.S Avasarala#, F Zhang#, G Liu, R Wang, SD London, and L London. Curcumin Modulates the Inflammatory Response and Inhibits Subsequent Fibrosis in a Model of Viral-induced Acute Respiratory Distress Syndrome,PLos One, 2013. 2. 20, 8(2): e57258 (#Co-first Author)
3.F Zhang, ZJiang, Y Zeng, T McCarthy. Developement of primers to characterize the mitochondrial control region of snow leopard (uncia uncia). Molecular Ecology Notes. 2007, 7(6): 1196-1198.
4.F Zhang, ZJiang. Mitochondrial phylogeography and genetic diversity of Tibetan gazelle (Procapra picticaudata): Implicatons for conservation. Molecular Phylogenetics and Evolution. 2006, 41: 313-321.
5.G Liu, F Zhang, R Wang, SD London, L London. Salivary gland immunization via Wharton’s duct activates differential T-cell responses within the salivary gland immune system, The FASEB Journal, 2019.
6.G Liu, F Zhang,R Wang, L London, SD London. Protective MCMV immunity by vaccination of the salivary gland via Wharton’s duct: replication-deficient recombinant adenovirus expressing individual MCMV genes elicits protection similar to that of MCMV, The FASEB Journal, 2014. 01. 03, 28(4): 1698-1710.
7.G Liu,F Zhang,J Shi, G Tian, H Chen, K Yu, Q Men. A subunit vaccine candidate derived from a classic H5N1 avian influenza virus in China protects fowls and BALB/c mice from lethal challenge, Vaccine, 2013. 11. 04, 31 (46):5389-5404.
8.K J Queen, M Shi, F Zhang, U Cvek and R S Scott. Epstein-Barr virus Induced Epigenetic Alterations Following Transient Infection. International Journal of Cancer, 2013. 05.01, 132(9):2076-2086.
9.K Ikuta, M Ding, F Zhang, J W. Sixbey and R S. Scott. Epithelial cell retention of transcriptionally active, P3HR-1-Derived heterogeneous (het) EBV DNA with concurrent loss of parental virus. Journal of Virology. 2011, 85(15): 7634-7543.
10.Y Luo, H Zhou, L Liu, T Shen, W Chen, B Xu, X Han, F Zhang, RS Scott,JS Alexander, A Alam and S Huang. The fungicide ciclopirox inhibits lymphatic endothelial cell tube formation by suppressing VEGFR-3-mediated ERK signaling pathway. Oncogene. 2010,1-10.
11.张芳芳，姜永萍，刘光亮，陈怀涛，乔传玲，陈化兰. 表达禽流感病毒H5HA、H7HA基因DNA疫苗的免疫原性研究.预防兽医学报.2006，28:1-5.
12.张芳芳，刘光亮，姜永萍，陈化兰，陈怀涛.禽流感病毒H5HA，H7HA基因共表达核酸疫苗质粒的构建及其在体外的表达. 动物医学进展.2004,25:107-110
13.张芳芳，陈化兰，陈怀涛.增强DNA疫苗免疫效果的研究进展.动物医学进展.2004，5:41-43.
14.姜永萍，李呈军，张洪波，步志高，张芳芳，邓国华，于康震，陈化兰.含有鸡体偏嗜性密码子的H5亚型禽流感病毒HA基因的优化构建及其DNA疫苗体外瞬时表达研究.预防兽医学报.2005，27:441-444,449.