基本情况
姓名：邱立勤
性别：男
籍贯：安徽桐城
职位：博士，教授，博士生导师，应用化学系主任，兼任广东省化学会有机化学专业委员会副主任，XJRL教育部重点实验室学术委员会委员
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联系方式
电话：
传真：暂未填写
邮箱：qiuliqin@mail.sysu.edu.cn, liqinqiu@hotmail.com
通讯地址：广东省广州市中山大学化学南楼203
邮编：510275
个人网站：暂未填写
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教育经历
1999年—2003年：香港理工大学应用生物与化学科技学系攻读博士学位；导师：陈新滋院士；?
1989年—1992年：天津大学化工系攻读硕士学位；导师：陈洪钫教授；?
1982年—1986年：合肥工业大学化工系攻读学士学位。
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工作经历
2007年—现在：教授，博导，中山大学 “****”第二层次引进人才。2009.3起任中山大学化学化工学院有机化学研究所所长，广东省化学 ?会理事、有机化学专业委员会副主任。2013.6起任中山大学化学化工学院应用化学系主任；?
2003年—2007年：博士后，香港理工大学陈新滋院士研究室；?
1992年—1999年：中国石化总公司—天津大学天津石油化工技术开发中心、天津大学化工学院化学工艺系教师，任工程师，副研究员（1997.11提前晋升），陈洪钫教授、米镇涛教授科研组；?
1986年—1989年：安徽化工学校教师。
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讲授课程
有机化学（本科），有机化学实验（本科），有机分离与结构分析（研究生），化学前沿进展（研究生）
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科研方向
手性合成与不对称催化，功能化学品的分子设计与合成，药物及中间体的合成与分离纯化，海洋资源化学，石油化工。
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科研项目
暂无资料
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获奖情况
暂无资料
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论著一览
1. Yougui Zhou, Xuepeng Zhang, Huiyi Liang, Zhenkun Cao, Xiaoyu Zhao, Yuwei He, Shouliang Wang, Jiyan Pang, Zhongyuan Zhou, Zhuofeng Ke,* and Liqin Qiu*. “Enantioselective Synthesis of Axially Chiral Biaryl Monophosphine Oxides via Direct Asymmetric Suzuki Coupling and DFT Investigations of the Enantioselectivity” ACS Catal. 2014, 4, 1390?1397.?
2. Qing Li, Pin Wan, Yuwei He, Yougui Zhou, Lanning Li, Bin Chen, Kun Duan, ?Rihui Cao, Zhongyuan Zhou and Liqin Qiu*. “Enantioselective Hydrogenation of the Double Bond of Exocyclic α,β-Unsaturated Carbonyl Compounds Catalyzed by Iridium/H8-BINOL-Derived Phosphine-Oxazoline Complexes” Asian J. Org. Chem. 2014, ASAP. DOI: 10.1002/ajoc..?
3. Yougui Zhou, Shouliang Wang, Wenhao Wu, Qing Li, Yuwei He, Yue Zhuang,Lanning Li, Jiyan Pang, Zhongyuan Zhou, and Liqin Qiu*. ?“Enantioselective Synthesis of Axially Chiral Multifunctionalized Biaryls via Asymmetric Suzuki Miyaura Coupling” Org. Lett. 2013, 15, 5508–5511.Highlighted in SYNFACTS, 2014, 10(2), 0160.?
4. Lanning Li, Bin Chen, Yuanyuan Ke, Qing Li, Yue Zhuang, Kun Duan, Yichun Huang, Jiyan Pang,Liqin Qiu*. “Highly Efficient Synthesis of Heterocyclic and Alicyclic β2-Amino Acid Derivatives by Catalytic Asymmetric Hydrogenation” Chem. Asian J. 2013, 8, 2167–2174.?
5. Qing Li, Pin Wan, Shouliang Wang, Yue Zhuang, Lanning Li, Yougui Zhou,Yuwei He, Rihui Cao,Liqin Qiu*. Zhongyuan Zhou. “Synthesis of a class of new phosphine-oxazoline ligands and their applications in palladium-catalyzed asymmetric addition of arylboronic acids to isatins” Appl. Catal. A2013, 458, 201–206. ?
6. Shouliang Wang, Jinjin Li, Tingting Miao, Wenhao Wu, Qing Li, Yue Zhuang, Zhongyuan Zhou,Liqin Qiu*. “Highly Efficient Synthesis of a Class of Novel Chiral-Bridged Atropisomeric Monophosphine Ligands via Simple Desymmetrization and Their Applications in Asymmetric Suzuki-Miyaura Coupling Reaction” Org. Lett. 2012, 14, 1966–1969. Highlighted in SYNFACTS, 2012, 8(7), 0739.?
7. Wenhao Wu, Shouliang Wang, Yougui Zhou, Yuwei He, Yue Zhuang, Lanning Li, Longshu Wang,Liqin Qiu*. “Highly Diastereoselective Synthesis of Atropisomeric bridged P,N-ligands and Their Application in Asymmetric Suzuki-Miyaura Coupling Reaction” Adv. Synth. Catal. 2012, 354, 2395–2402.?
8. Yujun Guo, Guang Shao, Lanning Li, Wenhao Wu, Ruihong Li, Jinjin Li, Jian Song, Liqin Qiu*, Mahavir Prashad, Fuk Yee Kwong. “A general approach to the synthesis of β2-amino acid derivatives via highly efficient catalytic asymmetric hydrogenation of α-aminomethylacrylates” Adv. Synth. Catal.2010, 352, 1539–1553.?
9. Liqin Qiu, Mahavir Prashad*, Bin Hu, Kapa Prasad, Oljan Repi?, Thomas J. Blacklock, Fuk Yee Kwong, Stanton H. L. Kok, Hang Wai Lee, and Albert S. C. Chan *. “Enantioselective hydrogenation of α-aminomethylacrylates containing a free N-H group for the synthesis of β-amino acid derivatives”Proc. Natl. Acad. Sci. USA 2007, 104, 16787–16792（美国国家科学院院刊PNAS）.?
10. Liqin Qiu, Yue–Ming Li, Fuk Yee Kwong, Wing–Yiu Yu, Qing-Hua Fan, Albert S. C. Chan*. “Highly Efficient Asymmetric Hydrogenation of ?,?–Unsaturated Carboxylic Acids Catalyzed by Ru(II)–dipyridylphosphine Complexes” Adv. Synth. Catal. 2007, 349, 517–520.?
11. Liqin Qiu, Fuk Yee Kwong, Jing Wu, Wai Har Lam, Shusun Chan, Wing-Yiu Yu, Yue-Ming Li, Rongwei Guo, Zhongyuan Zhou, and Albert S. C. Chan*. “A New Class of Versatile Chiral-Bridged Atropisomeric Diphosphine Ligands: Remarkably Efficient Ligand Syntheses and Their Applications in Highly Enantioselective Hydrogenation Reactions” J. Am. Chem. Soc. 2006, 128, 5955–5965 (此文 列 JACS 2006年4─6月most-accessed articles top 10).?
12. Liqin Qiu, Jing Wu, Shusun Chan, Terry T.-L. Yeung, Jian-xin Ji, Rongwei Guo, Cheng-Chao Pai, Zhongyuan Zhou, Xingshu Li, Qing-Hua Fan，Albert S. C. Chan*. “Remarkably Diastereoselective Synthesis of a Chiral Biphenyl Diphosphine Ligand and Its Application in Asymmetric Hydrogenation” Proc. Natl. Acad. Sci. USA 2004, 101, 5815–5820（美国国家科学院院刊PNAS）.?
13. Albert S. C. Chan, Liqin Qiu. “Preparation of biphenyldiphosphine compounds” U.S. Pat. **, 2006, 8, 22.?
14. Liqin Qiu, Jianying Qi, Cheng-Chao Pai, Shusun Chan, Zhongyuan Zhou, Michael. C. K. Choi, Albert S. C. Chan*. “Synthesis of Novel Diastereomeric Diphosphine Ligands and Their Applications in Asymmetric Hydrogenation Reactions” Org. Lett. 2002, 4, 4599–4602.?
15. Jian Ying Qi, Liqin Qiu, Kim Hung Lam, Chiu Wing Yip, Zhong Yuan Zhou and Albert S. C. Chan*. “Highly efficient epoxidation of cyclic alkenes catalyzed by ruthenium complex” Chem. Commun. 2003, 1058–1059.?
16. Jian-Xin Ji, Liqin Qiu, Chiu Wing Yip, Albert S. C. Chan*. “A Convenient, One-Step Synthesis of Optically Active Tertiary Aminonaphthyl and Its Applications in the Highly Enantioselective Alkenylations of Aldehydes” J. Org. Chem. 2003, 68, 1589–1590.?
17. (Book chapter) Fuk Yee Kwong, Liqin Qiu, Wai Har Lam, Chan, A. S. C. In Advances in Organic Synthesis; Jenner, G., Ed.; Bentham: The Netherlands, 2005; Vol. 1, pp 261–299.?
18. Fuk Yee Kwong*, Hang Wai Lee, Liqin Qiu, Wai Har Lam, Yue-Ming Li, Hoi Lun Kwong, Albert S. C Chan*. “Rhodium-bisbenzodioxanphos complex-catalyzed homogeneous enantioselective Pauson-Khand-type cyclization in alcoholic solvents” Adv. Synth. Catal. 2005, 347(14), 1750–1754.?
19. Fuk Yee Kwong*, Yue Ming Li, Wai Har Lam, Liqin Qiu, Hang Wai Lee, Chi Hung Yeung, Kin Shing Chan, Albert S. C. Chan*. “Rhodium-catalyzed asymmetric aqueous Pauson-Khand-type reaction” Chem. Eur. J. 2005, 11(13), 3872–3880. ?
20. Fuk Yee Kwong*, Hang Wai Lee, Wai Har Lam, Liqin Qiu, Albert S. C Chan*. “Iridium-catalyzed cascade decarbonylation/highly enantioselective Pauson-Khand-type cyclization reactions”, Tetrahedron: Asymmetry 2006, 17(8), 1238–1252.?
21. Lailai Wang, Yue-Ming Li, Chiu-wing Yip, Liqin Qiu, Zhongyuan Zhou, Albert S. C. Chan*. “Synthesis of new chiral aryl diphosphite ligands derived from pyranoside backbone of monosaccharides and their application in copper-catalyzed asymmetric conjugate addition of diethylzinc to cyclic enones” Adv. Synth. Catal. 2004, 346(8), 947–953.?
22. Bing Yi, Qing-Hua Fan*, Guo-Jun Deng, Yue-Ming Li, Liqin Qiu, Albert S. C. Chan. “Novel Dendritic Diphosphine Ligands for Rh(I)-Catalyzed Asymmetric Hydrogenation: Remarkable Structural Effects on Catalytic Properities”. Org. Lett. 2004, 6, 1361–1364.?
23. Shichang Li, Cunzhou Shen, Wenyuan Guo, Xuefei Zhang, Shixin Liu, Fengyin Liang, Zhongliang Xu, Zhong Pei, Huacan Song,* Liqin Qiu, Yongcheng Lin and Jiyan Pang*. “Synthesis and Neuroprotective Action of Xyloketal Derivatives in Parkinson’s Disease Models”. Mar. Drugs2013, 11, 5159-5189.?
24. Buxi Shi, Rihui Cao *, Wenxi Fan, Liang Guo, Qin Ma, Xuemei Chen, Guoxian Zhang, Liqin Qiu, Huacan Song*. “Design, synthesis and in vitro and in vivo antitumor activities of novel bivalent β-carbolines” Eur. J. Med. Chem. 2013, 60, 10–22.?
25. Rihui Cao*, Wenxi Fan, Liang Guo, Qin Ma, Guoxian Zhang, Jianru Li, Xuemei Chen, Zhenghua Ren, Liqin Qiu. “Synthesis and structureeactivity relationships of harmine derivatives as potential antitumor agents” Eur. J. Med. Chem. 2013, 60, 135–143.?
26. J. Li, X. Lu, Q. Wu, G. Yu, Z. Xu, L. Qiu, Z. Pei, Y. Lin, J. Pang*. “Design, SAR, Angiogenic Activities Evaluation and Pro-Angiogenic Mechanism of New Marine Cyclopeptide Analogs” Curr. Med. Chem. 2013, 20, 1183–1194.?
27. Guoxian Zhang, Rihui Cao,* Liang Guo, Qin Ma, Wenxi Fan, Xuemei Chen, Jianru Li, Guang Shao, Liqin Qiu, Zhenghua Ren*. “Synthesis and structureeactivity relationships of N2-alkylated quaternary β-carbolines as novel antitumor agents” Eur. J. Med. Chem. 2013, 65, 21–31.?
28. 邱立勤, ?化学工艺学?第七章“烃类选择性氧化”, p315-371; 廖巧丽、米镇涛主编，“普通高等教育 ‘十五’国家级规划及面向21世纪课程教材”，化学工业出版社：北京，2001，8（此教材获中国石油和化学工业协会第六届石化优秀教材一等奖，2002年9月）?
29.邱立勤，辛苑，李津津. “一种四酰基葛根素的制备方法” CNA（中国专利）.?
30.邱立勤，郭御卷，黎蓝宁. “一种β-氨基酸或其衍生物的制备方法” CNA（中国专利公开）.?
31.邱立勤，王守亮，李津津，苗婷婷. “一类膦配体及其对映体或消旋体及其制备方法”专利申请号4.8（已公开）.?
32.邱立勤，吴文浩. “一类膦配体及其对映体或消旋体及其制备方法”专利申请号2.3（已公开）.?
33.邱立勤，李庆，万品. “膦-噁唑啉配体及其离子型金属配合物以及其对映体或消旋体制备方法与应用” 专利申请号2.7（已公开）.?
34. 邱立勤，周有桂. “2,2-官能化手性联芳基化合物、制备方法及其用途” 专利申请号7.2（已公开）.?
35. 邱立勤，周有桂. “一种轴手性氧膦及轴手性联芳基膦的制备方法” 专利申请号0.1.?
36. 田方田, 张香文, 赵海柱, 马国平, 邱立勤, 姜浩锡. “一种烷烃氧化催化剂及其制备方法”，中国发明专利 CN**C.
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相关成果
主要研究成果：?
1. 复杂官能化手性联芳的催化不对称合成研究（国家自然科学基金No. **）；?
2. 一类新型可调的手性膦配体的合成及其在不对称Suzuki反应中的应用（国家自然科学基金No. **）；?
3. 高效不对称催化氢化合成α-取代的β-氨基酸及其衍生物（国家自然科学基金No. **）；?
4. 轴向手性联芳合成新型催化体系研究（教育部博士点基金No 9）；?
5. 海洋生物天然产物化合物库（国家海洋局广东省海洋经济创新发展区域示范专项）；?
6. 新型单齿配体的合成及其在不对称催化中的应用（广东省自然科学基金S05）；?
7. 新型结构碳氢燃料裂解引发剂的合成与筛选；?
8. 不对称Suzuki反应在（-）-Rhazinilam类似物中的应用（中科院天然产物有机合成化学重点实验室开放基金，中科院上海有机化学研究所）；?
9. 用于碳-碳键形成反应的高性能配体及其催化剂开发（大亚湾区科技计划项目）；?
10. 聚苯乙烯颗粒表面性能提升工艺（大亚湾区科技计划项目）；?
11. 头孢克肟关键中间体合成工艺研究；?
12. 非对映选择性合成手性膦配体及其在不对称催化中的应用（香港政府卓越研究计划，美国专利U.S. Pat. **）；?
13. 高密度烃燃料研制（国家“八?五”科技攻关项目，此项目于1998年获国家教育部科技进步三等奖）；?
14. γ-丁内酯胺化制吡咯烷酮（国家科技成果，登记号：942835，天津市科技攻关项目）；?
15. 不对称氢化合成几种重要药物及其中间体（Novatis公司）；?
16. 丁烷选择性氧化制顺酐VPO催化剂的研究（中国发明专利 CN**C，中国石化重点科技项目）17．； 金刚烷合成新型催化体系研究（中国石化科技计划项目）；?
18. 反应注射成型制聚双环戊二烯研究（中国石化科技计划项目）；?
19. 基于天然药物的四乙酰基葛根素高效合成与分离纯化；?
20. 抗肿瘤药物“卡培他滨”合成技术开发；?
21. 美拉德反应与香精香料；?
22. 新型除草剂的开发。