基本情况?姓名：曹乾 (Cao Qian)
性别：女
出生年月：1982-12
籍贯：河南郑州
职位：副教授，硕士生导师（无机化学、化学生物学）
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联系方式?通讯地址：广州市新港西路135号中山大学化学学院, 邮编510275
联系电话：
电子邮件：caoqian3@mail.sysu.edu.cn
ORCID ID：orcid.org/0000-0002-2040-2942
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教育经历 2000年09月—2004年07月 中山大学生物科学专业，学士学位；
2004年09月—2005年12月 英国诺丁汉大学应用分子微生物专业，硕士学位；
2006年04月—2010年07月 英国诺丁汉大学化学专业，博士学位。
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工作经历?2011年01月—2013年09月? 芬兰赫尔辛基大学化学系，博士后；
2013年09月—至今 ? ? ? ? ? ? ?中山大学化学学院，讲师，副教授，硕士生导师
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讲授课程?波谱解析 （全英，2+2专业），波谱解析，基础化学实验（无机），无机化学实验，有机化学实验，大学化学实验III。
?科研方向?生物无机化学，金属基抗肿瘤药物、诊断试剂及纳米载药体系
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科研项目 主持了包括国家自然科学基金青年基金、广东省自然科学基金面上项目、广州市科技计划项目、中央高校基本业务费青年教师培育项目等项目，参加了国家自然科学基金重点项目一项。
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获奖情况 2014 .11，中山大学“芙兰奖”(排名第6)
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专利一览曹乾，方浩吉，杨靖，毛宗万，黄华珍。一种环金属铱二甲双胍配合物及其制备方法和应用。专利号：9.4（已授权）。
曹乾，杨刚刚，毛宗万，黄华珍，计亮年。一种槲皮素金属纳米药物及其制备方法和应用。申请号：0.2。
毛宗万，周丹捷，杨刚刚，潘正银，曹乾，黄华珍。一种碳酸酐酶靶向的四价铂配合物及其制备方法和应用。专利号：9.8（已授权）。
毛宗万，钟毅芳，张航，黄华珍，曹乾。 一种具有双光子吸收特性的铂配合物及其制备方法和应用。申请号：7.5 。
?论著一览 2021
J. Yang^#, H-J. Fang^#, Q. Cao* and Z.-W. Mao*. Design of Cyclometalated Iridium(III)-Metformin Complexes for Hypoxic Cancer Treatment. Chem. Comm. 202, 57, 1093-1096.（Front Cover）IF=5.996
2020
Q. Cao^#, D-J. Zhou^#, Z-Y. Pan^#, G-G. Yang, H. Zhang, L.-N. Ji and Z.-W. Mao*. CAIXplatins: Highly Potent Platinum(IV) Prodrugs Selective Against Carbonic Anhydrase IX for the Treatment of Hypoxic Tumors. Angew. Chem. Int. Ed. 020, 59, 18556-1856. IF=12.959
G-G. Yang^#, Z-Y. Pan^#, D-Y, Zhang, Q. Cao*, L.-N. Ji and Z.-W. Mao*. Precisely-assembled Nanoparticles Against Cisplatin-Resistance via Cancer-specific Targeting of Mitochondria and Imaging Guided Chemo-Photothermal Therapy. ACS Appl. Mater. Interfaces, 2020, 12, 4444-43455. IF=8.758
2019
G-G. Yang, D-J. Zhou, Z-Y. Pan, J. Yang, Q. Cao*, J. Yang, D-Y, Zhang, L.-N. Ji and Z.-W. Mao*. Multifunctional low-temperature photothermal nanodrug with in vivo clearance, ROS-Scavenging and anti-inflammatory abilities. Biomaterials, 2019, 216, 119280. IF=10.317
K-N. Wang, Q. Cao*, L-Y. Liu, Z-J. Zhao, W-T. Liu, D-J. Zhou, C-P. Tan, W. Xia, L.-N. Ji and Z.-W. Mao*Charge-Driven Tripod Somersault on DNA for Ratiometric Fluorescence Imaging of Small Molecules in Nucleus. Chem. Sci. 2019, 10, 1003 – 10064. IF=9.346
Q. Cao^#, J. Yang^#, H. Zhang, L, Hao, G-G. Yang, L.-N. Ji, and Z.-Wan Mao*. Traceable In-cell Synthesis and Cytoplasm-to-Nucleus Translocation of A Schiff base Zinc Complex as A Simple and Economical Anticancer Strategy. Chem. Comm. 2019, 55, 7852 – 7855. IF=5.99 ?
J. Yang, L-L. Sun, L, Hao, G-G. Yang, Z-C. Zou, Q. Cao*, L.-N. Ji, and Z.-Wan Mao*. A halogen ion-selective phosphorescence turn-on probe based on induction of Pt–Pt interactions. Chem. Comm. 2019, 55, 11191 – 11194. IF=5.996?
2018
G-G. Yang, H. Zhang, D-D. Yang, Q. Cao*, J. Yang, L.-N. Ji and Z.-W. Mao*. Cancer-specific chemotherapeutic strategy based on the vitamin K3 mediated ROS regenerative feedback and visualized drug release in vivo. Biomaterials, 201, 185, 73–85. IF=10.317
J. Yang, Q. Cao*, H. Zhang, L. Hao, Zhou, Z-J Gan, Z-W. Li.; Y.-X. Tong, L.-N. Ji, and Z.-Wan Mao*. Targeted reversal and phosphorescence lifetime imaging of cancer cell metabolism via a theranostic rhenium(I)-DCA conjugate. Biomaterials, 2018, 176, 4-105. IF=10.317?
G-G. Yang, L. Hao, Q. Cao*, H. Zhang, J. Yang, L.-N. Ji and Z.-W. Mao*. Three-in-One Self-assembled Nanocarrier for Dual-Drug Delivery, Two-Photon Imaging, and Chemo-Photodynamic Synergistic Therapy. ACS Appl. Mater. Interfaces, 2018, , 28301–28313. IF=8.758
J. Yang, Q. Cao*, L, Hao, W-L. Hu, G-G. Yang, L.-N. Ji, and Z.-Wan Mao*. A Self-Assessed Photosensitizer: Inducing and Dual-Modal Phosphorescence Imaging of Mitochondria Oxidative stress. Chem. Comm. 2018, 54, 271–274. IF=5.996
2017
J. Yang^#, J-X, Zhao^#, Q. Cao*, L, Hao, D-X, Zhou, Z-J Gan, L.-N. Ji, and Z.-Wan Mao*. Simultaneously Inducing and Tracking Cancer Cell Metabolism Repression by Mitochondria-Immobilized Rhenium(I) Complex. ACS Appl. Mater. Interfaces, 2017, 9, 13900–139. IF=8.758
J. Yang, Q. Cao*, W-L. Hu, R-R Ye, L. He, L.-N. Ji, Peter Z. Qin and Z.-Wan Mao*. Theranostic TEMPO-functionalized Ru(II) complexes as photosensitizers and oxidative stress indicators. Dalton Trans. 2017, 46, 445-454. IF=4.099
Q. Cao, Y. Li, E. Freisinger, P. Z. Qin,^* R. K. O. Sigel,^* and Z.-W Mao*. G-quadruplex DNA targeted metal complexes acting as potential anticancer drugs.? Inorg. Chem. Front. 2017, 4, 10-32.（ESI高被引论文）IF=5.958?
2016- before
X.-H. Zheng, G. Mu, Y.-F. Zhong, T.-P. Zhang, Q. Cao*, L.-N. Ji, Y. Zhao and Z.-W. Mao*. Trigeminal star-like platinum complexes induce cancer cell senescence through quadruplex-mediated telomere dysfunction. Chem. Comm. 2016, 52, 14101-14104.?
M. Hu, J. Zhao, X. Ai, M. Budanovic, J. Mu, R. D. Webster, Q. Cao*, Z.-W Mao* and B.G. Xing*. Near infrared light-mediated photoactivation of cytotoxic Re(I) complex by lanthanide-doped upconversion nanoparticles. Dalton Trans. 20, 45, 14101-14108.?
X.-H. Zheng^#, Q. Cao^#, Y.-L. Ding, Y.-F. Zhong, G. Mu, P. Z. Qin, L.-N. Ji, Z.-W. Mao*. Platinum(II) clovers targeting G-quadruplexes and their anticancer activities. Dalton Trans. 2015, 44, 50-53.
Q. Cao, N. Andrijchenko,A. Ermilov, M. R?s?nen, A. V. Nemukhin,L. Khriachtchev*. Interaction of Aromatic Compounds with Xenon: Spectroscopic and Computational Characterization for the Cases of p-creosl and Toluene. J. Phys. Chem. A 2015, 119 (11), 2587–2593.
Q. Cao, G. Y. Gor, K. Krogh-Jespersen, L. Khriachtchev*. Non-covalent interaction of nitrous oxide with aromatic compounds: Spectroscopic and computational evidence for the formation of 1:1 complexes. J. Chem. Phys. 2014, 140, 144304.
Q. Cao, S. Berski, M. R?s?nen, Z. Latajka, L. Khriachtchev*. Reaction of atomic hydrogen with formic acid. Phys. Chem. Chem. Phys. 14, 16, 5993-6001.
Q. Cao, S. Berski, M. R?s?nen, Z. Latajka, L. Khriachtchev*. Spectroscopic and computational characterization of the HCO^...H₂O complex. J. Phys. Chem. A 2013, 117, 4385-4393.
Q. Cao, N. Andrijchenko,A.-E. Ahola,A. V. Domanskaya,M. R?s?nen,A. Ermilov,A. V. Nemukhin,L. Khriachtchev*. Interaction of Phenol with Xenon and Nitrogen: Spectroscopic and Computational Characterization. J. Chem. Phys. 2012, 137, 134305.
Q. Cao, M. Melavuori, J. Lundell, M. R?s?nen, L. Khriachtchev*. Matrix-isolation and ab initio study of the complex between formic acid and xenon. J. Mol. Struct. 2012, 1025, 132.
Q. Cao, C. M. Creely, E. S. Davies, J. Dyer, T. Easun, D. C. Grills, D. A. McGovern, J. McMaster, J. Pitchford, J. A. Smith, X.-Z. Sun, J. M. Kelly, M. W. George*.Excited state Dependent Electron Transfer of Re-dppz Intercalator in DNA: A time-resolved UV-Visible and IR Absorption Investigation into the Photophysics of fac-[Re(CO)3(dppz-F₂)(py)]⁺ Bound to Either [poly(dA-dT)]₂ or [poly(dG-dC)]₂. Photochem. Photobiol. Sci. 2011, 10, 1355-1364.
Q. Cao^#, X. Guan^#, M. W. George*, D. L. Phillips*, C. Ma, W. M. Kwok, M. Li, Y. Du, X.-Z. Sun, J. Xue.Ultrafast time-resolved infrared and resonance Raman spectroscopic study of the photo-deprotection and rearrangement reactions of p-hydroxyphenacyl caged phosphates. Faraday Discuss. 2010, 145, 171-183.