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中山大学生命科学学院导师教师师资介绍简介-朱颖

本站小编 Free考研考试/2021-05-20


朱颖

Submitted on 周一, 10/30/2017 - 21:15


性别


个人主页
http://shimeigroup.sysu.edu.cn/htmls/default_zh.html

工作电话


电子邮件
zhuy68@mail.sysu.edu.cn

职称
副教授

导师类型
硕士生导师

学历
理学博士

学科方向
0710生物学-10生物化学与分子生物学


研究方向
肿瘤发生发展的分子机制;
非编码RNA功能;
肿瘤代谢调控网络。

个人经历
教育经历:
2002/09-2006/06,中山大学,生命科学学院生物科学与技术系,生物科学专业,理学学士学位
2006/09-2011/06,中山大学,生命科学学院生物化学系,生物化学与分子生物学专业,理学博士学位
工作经历:
2011/09-2017/02,美国南加州大学,微生物分子学与免疫学系,研究助理(博士后)
2017/02至今,中山大学,生命科学学院,副教授

讲授课程
一般通识课《生活中的生物学》
专业选修课《肿瘤生物学》《细胞生物学II》
专业必修《细胞生物学实验》

学术成就
长期致力于非编码RNA的功能及其在癌变过程中作用的研究,在国际杂志上发表论文17篇,总影响因子IF约118.4点,其中IF>5的论文13篇;以第一、共一或共同通讯作者在Hepatology、Nucleic Acids Res、PLoS Pathog、MBio等国际知名刊物发表研究论文9篇,1篇论文被Faculty of 1000推荐阅读。论文总他引超950次,第一、共一或共同通讯作者论文的总他引超500次,2篇论文为ESI高被引论文。
作为第二完成人获2018年教育部自然科学一等奖;作为第四完成人获2018年广东省自然科学一等奖。
担任“Frontiers Cell and Developmental Biology”等杂志编委会成员和PLoS Pathogens等11本科学杂志审稿人。

承担课题
国家自然科学基金面上项目、青年项目;
科技部国家重点研发计划子课题;
广东省自然科学基金面上项目。
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论文专著
第一、共一及通讯作者论文:
Xu T, Zhu Y, Xiong Y, Ge YY, Yun JP, Zhuang SM. MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells, Hepatology. 2009 Jul;50(1):113-21.(共同第一作者)(IF: 14.971)?
Zhu Y, Lu Y, Zhang Q, Liu JJ, Li TJ, Yang JR, Zeng C, Zhuang SM. MicroRNA-26a/b and their host genes cooperate to inhibit the G1/S transition by activating the pRb protein, Nucleic Acids Res. 2012 May;40(10):4615-25. (共同第一作者)(IF: 11.147)
Lei X, Zhu Y, Jones T, Bai Z, Huang Y, Gao SJ. A Kaposi's sarcoma-associated herpesvirus microRNA and its variants target the transforming growth factor β pathway to promote cell survival, J Virol. 2012 Nov;86(21):11698-711. (共同第一作者)(IF: 4.324)
Zhu Y, Haecker I, Yang Y, Gao SJ, Renne R.? γ-Herpesvirus-encoded miRNAs and their roles in viral biology and pathogenesis, Curr Opin Virol. 2013 Jun;3(3):266-75. (IF: 5.400)
Zhu Y, Huang YF, Jung JU, Lu C, Gao SJ. Viral miRNA targeting of bicistronic and polycistronic transcripts. Curr Opin Virol. 2014 Aug; 7:66-72. (IF: 5.400)
Zhu Y, Ramos da Silva S, He M, Liang Q, Lu C, Feng P, Jung JU, Gao SJ. An oncogenic virus promotes cell survival and cellular transformation by suppressing glycolysis. PLoS Pathog. 2016 May;12(5): e**.? (IF: 6.463)
Zhu Y, Li T, Ramos da Silva S, Lee JJ, Lu C, Eoh H, Jung JU, Gao SJ. A critical role of glutamine and asparagine γ-nitrogen in nucleotide biosynthesis in cancer cells hijacked by an oncogenic virus. MBio.?2017 Aug 15;8(4). pii: e01179-17. (IF: 6.747)
Wang YL, Liu JY, Yang JE, Yu XM, Chen ZL, Chen YJ, Kuang M, Zhu Y, Zhuang SM. Lnc-UCID promotes G1/S transition and hepatoma growth by preventing DHX9-mediated CDK6 downregulation. Hepatology. 2019 Jul;70(1):259-275.(共同通讯作者)(IF: 14.971)?
Lin YF, Xiao MH, Chen HX, Meng Y, Zhao N, Yang L, Tang H, Wang JL, Liu X, Zhu Y, Zhuang SM. A novel mitochondrial micropeptide MPM enhances mitochondrial respiratory activity and promotes myogenic differentiation. Cell Death Dis. 2019 Jul 11;10(7):528.(共同通讯作者)(IF: 5.959)
合作者论文:
Xu T, Zhu Y, Wei QK, Yuan Y, Zhou F, Ge YY, Yang JR, Su H, Zhuang SM. A functional polymorphism in the miR-146a gene is associated with the risk for hepatocellular carcinoma, Carcinogenesis. 2008 Nov;29(11):2126-31. (IF: 4.004)
Moody R, Zhu Y, Huang Y, Cui X, Jones T, Bedolla R, Lei X, Bai Z, Gao SJ. KSHV microRNAs mediate cellular transformation and tumorigenesis by redundantly targeting cell growth and survival pathways, PLoS Pathog. 2013 Dec;9(12):e**. (IF: 6.463)
Bai Z, Huang Y, Li W, Zhu Y, Jung JU, Lu C, Gao SJ. Genomewide mapping and screening of Kaposi's Sarcoma-Associated Herpesvirus (KSHV) 3' untranslated regions identify bicistronic and polycistronic viral transcripts as frequent targets of KSHV microRNAs, J Virol. 2014 Jan;88(1):377-92. (IF: 4.324)
Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang SM. MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3. Mol Cancer. 2014 Feb 24;13:35. (IF: 10.679)
Lee MS, Yuan H, Jeon H, Zhu Y, Yoo S, Shi S, Krueger B, Renne R, Lu C, Jung JU, Gao SJ. Human mesenchymal stem cells of diverse origins support persistent infection with Kaposi’s Sarcoma-Associated Herpesvirus and manifest distinct angiogenic, invasive, and transforming phenotypes. MBio. 2016 Jan 26;7(1):e02109-15. (IF: 6.747)
Li W, Yan Q, Ding X, Shen C, Hu M, Zhu Y, Qin D, Lu H, Krueger BJ, Renne R, Gao SJ, Lu C. The SH3BGR/STAT3 pathway regulates cell migration and angiogenesis induced by a gammaherpesvirus microRNA. PLoS Pathog. 2016 Apr 29;12(4):e**. (IF: 6.463)
Li T, Zhu Y, Cheng F, Lu C, Jung JU, Gao SJ. Oncogenic Kaposi's Sarcoma-Associated Herpesvirus upregulates argininosuccinate synthase 1, a rate-limiting enzyme of the citrulline-nitric oxide cycle, to activate the STAT3 pathway and promote growth transformation. J Virol. 2019 Feb 5;93(4). pii: e01599-18. (IF: 4.324)
Xie C, Zhang LZ, Chen ZL, Zhong WJ, Fang JH, Zhu Y, Xiao MH, Guo ZW, Zhao N, He X, Zhuang SM*. A novel hMTR4-PDIA3P1-miR-125/124-TRAF6 regulatory axis and its function in NF-κB signaling and chemoresistance. Hepatology. 2020 May;71(5):1660-1677. (IF: 14.971)
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*2019年影响因子
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