个人简介：??????医学博士，教授，博士导师，寄生虫学教研室主任，八年制医学生全程导师，兼任海南医学院副校长（挂职），玛希隆大学（Mahidol University）客座教授。2005年于中南大学湘雅医学院获医学博士学位，2007年于中山大学中山医学院博士后出站并留校。2012年被选拔为国家留学基金“青年骨干教师”赴美国韦恩州立大学医学院公派留学一年。近年来一直从事分子病原生物学、病原疫苗开发与药物研制、重要入侵病原快速溯源等领域的研究工作。主持国家重点研发项目课题、国家自然科学基金（4项）、广东省国际科技合作重点项目等24项课题，经费总额超过1千万。在国内外专业学术期刊发表论文超过100篇，其中SCI论文60余篇（通讯作者/第一作者42篇）。获得3项国家发明专利、5项实用新型专利以及1项省部级科学进步一等奖。主编、参编国家规划教材11部，参编、审阅科普书籍和视频数十部。主持3项教学改革项目（含1项重点项目），获广东省教学成果一等奖1项。主持12项国家级和省级大学生创新训练项目等本科生科研项目，指导学生3次获得“全国大学生基础医学创新论坛暨实验设计大赛”一等奖。
导????师：博士导师，硕士导师
学科专业：病原生物学
重要学术研究成果与贡献：?
学术论著（近5年）：???????
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1. Zhou HL, Zhou MY, Hu Y,?Limpanont?Y,?Ma YB, Huang P,?Dekumyoy?P, ?Maleewong?W,?Lv ZY*.?TNF-α triggers RIP1/FADD/caspase-8 mediated apoptosis of astrocytes and?RIP3/MLKL mediated necroptosis of neurons induced by?Angiostrongylus cantonensis?infection. Cell Mol Neurobiol. 2021.
2. Song LG*,?Xie QX, Lao HL, Lv ZY*. Human coronaviruses and therapeutic drug discovery.?Infect Dis Poverty. 2021.?
3.?Yue Hu, Jiansong Chen, Yiyue Xu, Hongli Zhou, Ping Huang, Ma Yubin, Minzhao Gao, Shaoyun Cheng, Haiyun Zhou, Zhiyue Lv*. Alterations of gut microbiome and metabolite profiling in mice infected by?Schistosoma japonicum. Front Immunol. 2020,10.3389/fimmu.2020.569727.?
4.?Yue Hu, Hanguo Xie, Minzhao Gao, Ping Huang, Hongli Zhou, Ma Yubin, Minyu Zhou, Jinying Liang,?Jun Yang*,?Zhiyue Lv*.?Dynamic of composition and diversity of gut microbiota in?Triatoma rubrofasciata?in different developmental stages and environmental conditions. Front Cell Infect Microbiol. 2020,10.3389/?fcimb.2020.587708.
5.?Hongli Zhou, Xiaojing Zeng, Dongchen Sun, Zhe Chen, Weixin Chen, Liwei Fan, Yanin Limpanont, Paron Dekumyoy, Wanchai Maleewong,?Zhiyue Lv*.?Monosexual cercariae of?Schistosoma japonicum?infection protects against DSS-induced colitis by shifting the Th1/Th2 balance and modulating the gut microbiota.?Front Microbiol.?2020.
6.?Minyu Zhou, Yunfei Zhou, Yixin Chen, Yanqi Wu, Jun Yang*, Zhiyue Lv*. Application of gold-based nanomaterials in tumor Photothermal therapy and chemotherapy. J Biomed Nanotechnol.?2020, 16(6):739-762.
7.?Huang?P,?Zhou MY, Cheng SY, Hu Y, Gao MZ, Ma YB,?Limpanont?Y,?Zhou HL,?Paron D,?Cheng YX, Lv ZY*. Myricetin possesses anthelmintic activity and attenuates hepatic fibrosis via modulating TGFβ1 and Akt signaling and shifting Th1/Th2 balance in?Schistosoma japonicum-infected mice. Front Immunol. 2020,10.3389/fimmu.2020.00593.
8.?Zhou HL, Chen Z, Limpanont Y, Hu Y, Ma YB, Huang P, Paron D, Zhou MY, Cheng YX, Lv ZY*. Necroptosis and caspase-2-mediated apoptosis of astrocytes and neurons, but not microglia, of rat hippocampus and parenchyma caused by?Angiostrongylus cantonensis?infection. Front Microbiol. 2020,10:3126.
9.?Zhao LL, Liu H, Xing YL, Wang R, Cheng ZY, Lv CZ*, Lv ZY*, Yu FB*.?Tumor?microenvironment?-?specific?functional?nanomaterials for?biomedical?applications. J Biomed Nanotechnol.?2020, 16(9): 1325-1358.
10.?Jiang HJ, Nan J, Lv ZY*, Yang J*.?Psychological impacts of the COVID-19 epidemic on Chinese people: Exposure, post-traumatic stress symptom, and emotion regulation. Asian Pac J Trop Med. 2020;13:252-259.
11.??Xu L, Xu M, Sun X, Xu JY, Zeng X, Shan D, Yuan DJ, He P, He WM, Yang YL, Luo SQ, Wei J, Wu XY, Liu Z, Xu XM, Dong ZS, Song LG, Zhang BB, Yu ZL, Wang LF, Zhang C, Fang XD, Gao Q*, Lv ZY*, Wu ZD*. The genetic basis of adaptive evolution in parasitic environment from the?Angiostrongylus cantonensis?genome. PLOS Neglect Trop D, 2019,13(11):e**.
12.?Zhang HR, Wu YQ, Hu Y, Li XF*, Zhao MY*, Lv ZY*.Targeted nanoparticle drug delivery system for the enhancement of cancer immunotherapy.?J Biomed Nanotechnol.?2019,15(9): 1839-1866.
13.?Shen SS, Qu XY, Zhang WZ, Li J, Lv ZY *.?Infection against infection: Parasite antagonism against parasites, viruses and bacteria. Infect Dis Poverty. 2019,8(1):49.
14.?Hu Y, Gao MZ, Huang P, Zhou HL, Ma YB, Zhou MY, Cheng SY, Xie HG*, Lv ZY*.Taxonomic integrative and phylogenetic identification of the first recorded?Triatoma rubrofasciata?in Zhangzhou, Fujian Province and Maoming, Guangdong Province, China. Infect Dis Poverty. 2019, 8(1):70.
15.?Deng MH, Zhong LY, Kamolnetr O, Limpanont Y, Lv ZY*. Detection of helminths by loop-mediated isothermal amplification assay: A review of updated technology and future outlook. Infect Dis Poverty. 2019,8(1):20.
16.?Zhu GL, Tang YY, Limpanont Y, Wu ZD, Li J*, Lv ZY*. Zoonotic parasites carried by invasive alien species in China. Infect Dis Poverty. 2019 8(1):2.
17.?Liu XL, Zhu GL, Cai CN, Lv ZY*, Li J*.?Clonorchiasis sinensis?detected by laparoscopic exploration of biliary tracts in two patients with obstructive jaundice. BMC Infec Dis. 2019,19(1):33.?
18.?Wu YQ, Liu JQ, Lin YF, Weng RN, Chen R, Li J, Lv ZY*. Diagnosis, Monitoring, and Control of Schistosomiasis - An Update. J Biomed Nanotechnol. 2018,14(3):430-455.
19.?Lu XT, Gu QY, Limpanont Y, Song LG, Wu ZD, Okanurak K, Lv ZY*. Snail-borne parasitic diseases: an update on global epidemiological distribution, transmission interruption and control methods. Infect Dis Poverty. 2018,7(1):28.
20.?Mengying Z, Yiyue X, Tong P, Yue H, Limpanont Y, Ping H, Okanurak K, Yanqi W, Dekumyoy P, Hongli Z, Watthanakulpanich D, Zhongdao W, Zhi W, Zhiyue L*. Apoptosis and necroptosis of mouse hippocampal and parenchymal astrocytes, microglia and neurons caused by?Angiostrongylus cantonensis?infection. Parasit Vectors. 2017,10(1):611.
21.?Liu J, Xu YY, He XJ, Zheng MH, Zhang MY, Hu Y, Wu YQ, Song LG, Zeng X, Lin DT, Wang S, Zheng HQ, Wu ZD, Lv ZY*. Study on the tolerance and adaptation of rats to?Angiostrongylus cantonensis?infection. Parasitol Res. 2017, 116(7):1937-1945.
22.?Zheng SH, Zhu Y, Zhao ZJ, Wu ZD, Okanurak K, Lv ZY*. Liver fluke infection and cholangiocarcinoma: a review. Parasitol Res. 2017,116(1):11-19.?
23.?Wang M, Wu LX, Weng RN; Zheng WH, Wu ZD, Lv ZY*. Therapeutic potential of helminths in autoimmune diseases: helminth-derived immune-regulators and immune balance. Parasitol Res. 2017, 116(8):2065-2074.
24.?Lin WH, Chen R, He XJ, Wu ZD, Paron D, Lv ZY*. Parasites and asthma. Parasitol Res. 2017,116(8):2373-2383.
25.?He P, Song LG, Xie H, Liang JY, Yuan DY, Wu ZD, Lv ZY*. Nucleic acid detection in the diagnosis and prevention of schistosomiasis. Infect Dis Poverty. 2016,5:25.?
26.?Xi Sun, Lifu Wang, Ying Feng, Hui Xie, Xiaoying Zheng, Ai He, Md Robiul Karim, Zhiyue Lv*,?Zhong-Dao Wu*.?A case report: A rare case of infant gastrointestinal canthariasis caused by larvae of?Lasioderma serricorne?(Fabricius, 1792) (Coleoptera: Anobiidae).?Infect Dis Poverty. 2016,5:34.?
27.?Song LG, Wang ZW, Yang Z, Lv ZY*, Wu ZD*.?Angiostrongylus cantonensis?in the vector snails?Pomacea canaliculata?and?Achatina fulica?in China: a meta-analysis. Parasitol Res. 2016,115(3):913-923.
28.?Liu J, Pan T, You X, Xu Y, Liang J, Limpanont Y, Sun X, Okanurak K, Zheng H, Wu Z, Lv Z*. SjCa8, a calcium-binding protein from?Schistosoma japonicum, inhibits cell migration and suppresses nitric oxide release of RAW264.7 macrophages. Parasit Vectors. 2015,8:513.?
29.?Feng F, Feng Y*, Liu Z, Li WH, Wang WC, Wu ZD, Lv ZY*. Effects of albendazole combined with TSII-A (a Chinese herb compound) on optic neuritis caused by?Angiostrongylus cantonensis?in BALB/c mice, Parasites & Vectors. 2015,11(25):8
30.?Wei J, Wu F, He A, Zeng X, Ouyang LS, Liu MS, Zheng HQ, Lei WL, Wu ZD*, Lv ZY*. Microglia activation: one of the checkpoints in the CNS inflammation caused by?Angiostrongylus cantonensis?infection in rodent model. Parasitol Res. 2015,114(9):3247-3254.
31.?Lv ZY*, Wu ZD*, Zhang LM, Ji PY, Cai YF, Luo SQ, Wang HX, Li H. Genome mining offers a new starting point for parasitology research. Parasitol Res. 2015,114(2):399-409.?
32.?Ji PY, Hu HL, Yang XY, Wei XX, Zhu CC, Liu JC, Feng Y, Yang F, Okanurak K, Li N, Zeng X, Zheng HQ, Wu ZD, Lv ZY*. AcCystatin, an immunoregulatory molecule from?Angiostrongylus cantonensis, ameliorates the asthmatic response in an aluminium hydroxide/ovalbumin-induced rat model of asthma. Parasitol Res. 2015,114(2):613-624.?
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获奖及荣誉：? ?? 2010年入选为广东省高等学校“千百十”工程培养对象。2012年至今3次评为中山大学“优秀学生导师”。2014年、2016、2019 年评为中山大学“优秀党员”。2018年被评为中山大学“优秀党务工作者”、中山医学院“优秀教师”。
学术兼职：?? 国家卫生健康标准委员会专业委员会委员，广东省寄生虫学会秘书长，中国地方病协会热带病专业委员会委员，中华预防医学会医学寄生虫学分会教育学组委员会委员，广州市医学会细胞形态学诊断分会常务委员，《热带医学杂志》、《热带病与寄生虫学》常务编委。
其 他：? ???常年招收医学、药学和生物学专业的博士后及专职科研人员，诚挚欢迎加入团队！