学术简历
? 现任中山大学公共卫生学院卫生毒理系副教授，硕士生导师。中山大学卫生毒理学博士，美国马里兰大学药学院博士后。长期致力于环境毒理学研究。主持科研项目4项，包括国家自然科学基金面上和青年项目各1项、中山大学青年教师培育项目1项。在国内外期刊上参与发表论文30余篇，以第一、通讯（含共同）作者在Environmental Pollution、Science of the Total Environment、Aquatic Toxicology?、Toxicology and Applied Pharmacology、Toxicology?in Vitro、Toxicology?Research等杂志发表SCI论著。参与获得相关奖励6项、国家发明专利2项，参编专著2部。近年来的研究方向主要为：环境污染物致健康损害效应易感因素筛查及机制探讨。
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承担科研项目
主持项目
国家自然科学基金面上项目（2020-2023）
国家自然科学基金青年项目（2015-2017）
环境污染与疾病监控教育部重点实验室（贵州医科大学）开放项目（2018-2020）
高校基本科研业务费中山大学青年教师培育项目（2014-2017）
中山大学实验室开放基金项目（指导老师，2016-2017）
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参与项目: 作为主要成员参与国家级项目10余项
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近年来发表的主要期刊论文（#?第一作者，*?通讯作者）
Xiumei Xing^#, Zhini He^#, Ziwei Wang, Ziying Mo, Liping Chen, Boyi Yang, Zhengbao Zhang,?Shen Chen, Lizhu Ye, Rui Zhang,?Yuxin Zheng, Wen Chen,_?Daochuan Li^*.?Association?between H3K36me3 modification and methylation of LINE-1 and MGMT in peripheral blood lymphocytes of PAH-exposed workers. Toxicol Res (Camb), 2020, 9(5):661-668.
Zhengbao Zhang^#, Xiumei Xing^#,?Shuyun Jiang, Chunfang Qiu, Ziying Mo, Shen Chen, Liping Chen, Qing Wang, Yongmei Xiao, Guanghui Dong, Yuxin Zheng, Wen Chen, Daochuan Li?.?Global H3K79 di-methylation mediates DNA damage response to PAH exposure in?Chinese coke oven workers. Environ Pollut. 2020, online.
Xiumei Xing^#, Liwen Hu^#, Yuming Guo^#, Michael S. Bloom,?Shanshan Li, Gongbo Chen, Steve Hung Lam Yim, Namratha Gurram, Mo Yang, Xiang Xiao, Shuli Xu, Qi Wei, Hongyao Yu, Boyi Yang, Xiaowen Zeng, Wen Chen, Qiang Hu*, Guanghui Dong*.?Interactions between ambient air pollution and obesity on lung function in children: The Seven Northeastern Chinese Cities (SNEC) Study. Science of the Total Environment, 2019, 699(134379), 1-10.?
Zhini He^#, Rui Zhang^#, Shen Chen, Liping Chen, Huiyao Li, Lizhu Ye, Qiong Li,??Ziwei Wang, Qing Wang, Huawei Duan, Yong Niu, Yongmei Xiao, Guanghui Dong,?Daochuan?Li, Dianke Yu, Yuxin Zheng,?Xiumei Xing*,?Wen?Chen.FLT1 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation.?Environ Pollut. 2019,?252?(Pt A):607-615.??
Zhong X, Qiu J, Kang J, Xing X, Shi X, Wei Y. Exposure to tris(1,3-dichloro-2-propyl) phosphate (TDCPP) induces vascular toxicity through Nrf2-VEGF pathway in zebrafish and human umbilical vein endothelial cells. Environ Pollut. 2019, 247:293-301.
Xiumei Xing, Jianmeng Kang, Jiahuang Qiu, Xiali Zhong, Xiongjie Shi,?Bingsheng Zhou, Yanhong Wei*.Waterborne exposure to low concentrations of BDE-47 impedes early vascular development in zebrafish embryos/larvae. Aquat Toxicol.?2018, 203:19-27.??
Jie Li^#, Xiumei Xing^#, Xinjie Zhang^#, Boxuan Liang , Zhini He, Chen Gao,Shan Wang , Fangping Wang, Haiyan Zhang, Shan Zeng , Junling Fan, Liping Chen, Zhengbao Zhang, Bo Zhang , Caixia Liu, Qing Wang, Weiwei Lin, Guanghui Dong, Huanwen Tang, Wen Chen, Yongmei Xiao, Daochuan Li*, Enhanced H3K4me3 modifications are involved in the transactivation of DNA damage responsive genes in workers exposed to low-level benzene, Environ Pollut.?2018, 234:127-135.?
Chen Gao^#, Xiumei Xing^#, Zhini He, Shen Chen, Shan Wang, Qingye Li, Ping Guo, Haiyan Zhang, Huiyao Li, Liping Chen, Qing Wang, Jian Zhao, Yongmei Xiao, Wen Chen*, Daochuan Li*, Hypermethylation of PGCP gene is associated with human bronchial epithelial cells immortalization, Gene,?2018, 642:?505-512.
Fei Wang, Tao Guo, Hongmei Jiang, Ruobi Li, Ting Wang, Ni Zeng, Guanghui Dong,?Xiaowen Zeng, Daochuan Li, Yongmei Xiao, Qiansheng Hu, Wen Chen, Xiumei Xing*?and Qing Wang*. A comparison of CRISPR/Cas9 and siRNA-mediated ALDH2 gene silencing in human cell lines.?Molecular Genetics and Genomics. 2018. 293:769-783.?
Zhiqiang Zhao,?Xiumei Xing^#,Xiaoyan Ou, Xinxia Liu, Ridong Zhou,?Huimin Zhang, Liuqing Yang, Zhixiong Zhuang, Xiaolin Su,?Yao Lu, Jun Jiang, Yarui Yang,Dong Cui, Yun He*.?DNA Damage Levels in Electronics Workers in Southern China: A Micro-Whole Blood Comet Assay. Mutat Res Fund Mol Mech Mutagen, 2017, 803-805:?17-21.
莫子颖#，肖勇梅，邢秀梅*. 职业接触甲苯暴露生物标志物研究进展.职业与健康，2020年7月9日接受。
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发明专利
参与获得国家发明专利2项：ZL 2015 1 **.6；?ZL 2010 1 **.8
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学术专著
《现代毒理学》，参编第三十五章模式生物及其在毒理学中的应用； ?ISBN:978-7-117-26011-4/R.26012
《机制毒理学》，参编第二章机制毒理学研究的实验模型；ISBN:978-7-03-066806-6
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获奖情况（含参与）
?中国毒理学会第九次全国毒理学大会优秀论文奖
?中华预防医学会科技奖二等奖
?中山大学公共卫生学院2019年度优秀个人
?中山大学公共卫生学院全程导师月活动二等奖（导师）
?第十届中国科协年会优秀论文二等奖
?湖南省第十三届自然科学优秀学术论文三等奖
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招生专业
卫生毒理学
公共卫生硕士（MPH）
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联系方式
电子邮箱：xingxm3@mail.sysu.edu.cn
地址：广州市中山二路74号大院?中山大学公共卫生学院（邮编510080）
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