李冰石 职称：教授
办公电话：**
EMAIL：phbingsl@szu.edu.cn


基本信息
研究方向
代表论著
科研项目
荣誉获奖

基本情况介绍：
李冰石，三级教授，深圳市****基金获得者（2011），深圳大学优秀****（2015）。
2004年 中国科学院大学理学博士学位 （导师：白春礼院士/唐本忠院士）
1999/08-2001/07 香港科技大学物理系、化学系 研究助理 导师唐本忠院士
2004/09-2007/09 多伦多大学化学系，博士后（合作导师Cynthia Goh）。
聚集诱导发光分子（aggregation-induced emission, AIE）由香港科技大学唐本忠院士研究组最先发现并命名，目前是材料科学研究领域的第二大热点课题。本课题组研究方向包括AIE分子的设计、合成、光学性质及组装结构研究；圆偏振发光AIE体系的构筑；多重刺激响应AIE分子的设计和性质研究；两亲性AIE分子在表/界面上的组装行为研究；生物大分子间相互作用研究；功能高分子的光学性质和组装行为研究。
目前，已在国际著名杂志《Angew. chem》、《Adv.Func.Mater》、《ACS Nano》、《Nano Lett》、《Mater. Horizon》、 《Macromolecules》、 《J. Mater. Chem.C》、 《J. Phys. Chem. C》、 《Langmuir》等发表多篇有影响力的论文。多次在中国化学会手性科学会议和AIE国际会议做邀请报告。
课题组与唐本忠院士香港科大（港中文，深圳）、华南理工大学国家光电重点实验室长期开展合作研究，研究平台共享。
对学生基本要求：
勤于思考、勇于探索、大胆求证、锲而不舍。
课题组欢迎本科生、研究生、博士后申请。
课题组成员：
副研究员：黄光熙博士
博士后:Mohamed Ibrahim Halawa
研究助理：夏庆
研究生 2018：张洪岩、陈勇豪， 李莹波
2019：谢巍巍， 张俊倩，邬国星
2020： 马朝阳， 薄恒，胡佳丽
空缺职位： 课题组常年招收化学、材料及相关交叉学科的博士后

导师联系方式phbingsl@szu.edu.cn化学与环境工程学院B1座 309

研究方向
?圆偏振发光AIE材料的构筑
构建本征CPL材料和诱导手性CPL材料，通过液晶、手性小分子或手性溶剂诱导AIE分子产生圆偏振发光性质。

代表性工作一：
AIE分子/液晶共混体系的构筑，利用将军-士兵效应，诱导超分子液晶体系共组装产生圆偏振发光信号，论文。工作发表在ACS Nano, 2021 in press。

液晶分子与TPE衍生物共组装的手性放大示意图

代表性工作二：
利用手性胺与AIE聚合物之间的氢键作用，诱导体系产生圆偏振发光性质。工作发表在Macromolecules 2020, 53, 6288?6298


?发光纳米超螺旋纤维的构筑
通过氨基酸、胆固醇等手性取代基诱导AIE分子骨架产生螺旋构象形成超分子螺旋纤维。所制备的纳米/微米螺旋纤维具有圆二色性、圆偏振发光特性，是重要的发光微纳器件材料。

代表性工作一：
基于AIE小分子的发光纳米螺旋纤维的构筑
Small, 2016,12,6593-6601(封面论文)，共同第一作者为研究生。Materials Chemistry Frontiers, 2017, 1, 646 (封面论文)，第一作者为研究生。

课题组制备的具有圆偏振发光特性的蓝色荧光的超螺旋纤维


代表性工作二：
基于AIE高分子发光纳米囊泡、纳米纤维的制备（J. Mater. Chem. C. 2018,6,4807）


?超分子组装的表/界面研究
超分子结构的形成不仅决定于分子的化学结构，而且受环境因素，如溶剂、表面界面的影响。揭示分子化学结构与外部因素对分子组装的协同作用,对于设计具有特定结构的功能材料具有重要意义。

代表性工作一
J. Phys. Chem. C 2019, 123, 9292?9297，共同第一作者为研究生。


分子在溶液与界面组装的AFM图像和理论模拟

代表性工作二
缬氨酸取代四苯乙烯分子组装的界面效应（Langmuir. 2019, 35, 3805，第一作者为研究生)

（左）缬氨酸单取代四苯乙烯分子形成的不同超螺旋带、纤维。（右）缬氨酸双取代的四苯乙烯分子形成的不同超螺旋带、纤维

?多重刺激响应AIE材料的设计合成

代表性工作一：
设计基于TPE骨架的多重态力致变色和光致变色材料，并将其应用至多维防伪领域。代表性研究工作发表在Angew. Chem. Int. Ed. 2019, 58, 2–8.

分子多维防伪应用示意图

代表工作二：
设计基于AIE骨架的气体、pH响应、力致变色材料，代表性研究工作发表在材料学著名杂志Adv. Funct. Mater. 2019, 29, **，该研究工作被高分子科学前沿介绍。


分子对胺蒸汽的响应照片和多重力致变色性质制备的中国传统文化特色的“深圳大学”印章图案


代表论著：
43. Xia,Q.; Meng, L. M.; He, T. C.; Huang, G.X.*; Li. B. S.*; Tang, B. Z.* Direct Visualization of Chiral Amplification of Chiral AIE Molecules in Nematic Liquid Crystals, from Molecular Scale to the Bulk. ACS nano. 2021, in press.
42. Zhang, H. Y.; Li, W. L.; Huang, Q. Y.; Huang, G. X.; Chi, Z. G.; Li, B. S.*A multi-stimuli responsive tetraphenylethene derivative: Self-reversible mechanochromism, mechanoluminescence, switchable photochromism. Dyes and Pigments. 2021, 187, 109128
41. Halawa, M. I.; Mostafa, M.; Wu, G. X.; Li, B. S.*Amplified anodic electrogenerated chemiluminescence of tris(2,2′-bipyridyl)ruthenium(II) for ultrasensitive detection of bambuterol: Application to content uniformity testing. J. Electroanal. Chem. 2021, 880, 114881.
40. Jiang, Y.; Chang, X.; Xie, W.; Huang, G.; Li, B. S. Cyano-Containing Tetraphenylethene Isomers: Similar Bright Mechanoluminescence, but Diverse Recoverable Processes. Mater. Chem. Front2021, 5, 885-892.
39. Halawa, M. I.; Wu, G. X.; Li, B. S.*Development of luminol-based chemiluminescence approach for ultrasensitive sensing of Hg(II) using povidone-I2 protected gold nanoparticles as an efficient coreactant. Anal Bioanal Chem413, 649–659 (2021).
38. Zhang, H.; Zhang, H.; Huang, G.; Li, B. S.*Two Tetraphenylethene-Pyrene Isomers: Distinct Fluorescence and Mechanochromic Properties. Dyes and Pigments2021, 185, 108947.
37. Liu, Q.; Xia, Q.; Xiong, Y.; Li, B. S.*; Tang, B. Z. Circularly Polarized Luminescence and Tunable Helical Assemblies of Aggregation-Induced Emission Amphiphilic Polytriazole Carrying Chiral L-Phenylalanine Pendants. Macromolecules2020, 53, 6288-6298.
36. Halawa, M. I.*;Li, B. S.*; Xu, G.* Novel Synthesis of Thiolated Gold Nanoclusters Induced by Lanthanides for Ultrasensitive and Luminescent Detection of the Potential Anthrax Spores’ Biomarker. ACS Appl. Mater. Inter. 2020, 12, 32888-32897.
35. Huang, G.; Chang, X.; Jiang Y.; Lin B.; Li. B. S.*; Tang, B. Z.* Multi-stimuli responsive cyanostilbene derivatives: pH, amine vapor sensing and mechanoluminescence Mater. Chem. Front., 2020,4, 1720-1728.
34. Halawa, M. I.; Mostafa, I. M.; Tolba, M. M.; El-Shabrawy, Y.; Li, B. S.* Development of Ru(Bpy)32+-Amisulpride Electrogenerated Chemiluminescence System for Ultrasensitive and Selective Detection of Amisulpride in Pharmaceuticals and Real Plasma. J. Electroanal. Chem.2020, 864, 114059.
33. 夏庆，袁勤、Jason Ng, 唐本忠，李冰石.基于氨基酸取代的噻咯分子的超分子组装结构的构筑 功能高分子学报2019,32,705
32. Huang, G. X.; Xia, Q.; Huang, W. B.; Tian, J. W.; He, Z. K.; Li, B. S.*, Tang, B. Z.* Multiple Anti-Counterfeiting Guarantees from a Simple Tetraphenylethylene Derivative - High-Contrasted and Multi-State Mechanochromism and Photochromism, Angew. Chem. Int. Ed.2019, 58, 17978-17983.
31. Huang, G. X.; Jiang, Y. Q.; Wang, J. G.; Li, Z.;Li, B. S.*, Tang, B. Z.*The influence of intermolecular interactions and molecular packings on mechanochromism and mechanoluminescence – a tetraphenylethylene derivative case, J. Mater. Chem. C, 2019,7, 12709-12716.
30. Jiang, Y.; Wang, J; Huang, G.* Li Z., Li B. S.*, Tang, B. Z.* Insight from the old: mechanochromism and mechanoluminescence of two amine-containing tetraphenylethylene isomers, J. Mater. Chem. C. 2019, 7, 11790.
29. Chen, Y. T.; Xue, S.; Xia, Q.; Li, H. K.; Liu, Q. M.; Li, B. S.*and Tang, B. Z.* Surface Effect on The Self-Assembly of Nanofibers Revealed by in Situ AFM Imaging and Molecular Simulation J. Phys. Chem. C2019, 123, 9292-9297.
28. Zhang, J.; Liu, Q.; Wu, W.; Peng, J.; Zhang, H.; Song, F.; He, B.; Wang, X.; Sung, H. H. Y.; Chen, M.; Li, B. S.*; Liu, S. H.; Lam, J. W. Y.; Tang, B. Z.* Real-Time Monitoring of Hierarchical Self-Assembly and Induction of Circularly Polarized Luminescence from Achiral Luminogens. ACS Nano2019, 13, 3618-3628.
27. Huang, G.; Jiang, Y.; Yang, S.; Li, B. S.; Tang, B. Z. Multistimuli Response and Polymorphism of a Novel Tetraphenylethylene Derivative. Adv. Funct. Mater. 2019, 29, **.
26. Li, B. S.*; Huang, X. J.; Li, H. K.*; Xia, W. J.; Xue, S.; Xia, Q.; Tang, B. Z.*; Solvent and Surface/Interface E?ect on the Hierarchical Assemblies of Chiral Aggregation-Induced Emitting Molecules,Langmuir 2019, 35, 3805?3813
25. Li, H.; Li, B. S.*; Tang, B. Z.* Molecular Design, Circularly Polarized Luminescence, and Helical Self-Assembly of Chiral Aggregation-Induced Emission Molecules. Chemistry – An Asian Journal2019, 14, 674-688.
24. Huang, G.; Wen, R.; Wang, Z.; Li, B. S.; Tang B. Z.* Novel chiral aggregation induced emission molecules: self-assembly, circularly polarized luminescence and copper(II) ion detection Mater. Chem. Front.2018, 2, 1884
23. Liu, Q.; Xia, Q.; Wang, S.; Li, B. S.*; Tang B. Z.* In situ visualizable self‐assembly, aggregation induced emission and circularly polarized luminescence of tetraphenylethene and alanine based chiral polytriazole J. Mater. Chem. C. 2018,6,4807
22. Xue, S.; Meng, L.; Wen, R.; Shi, L.; Lam, J. W.; Tang, Z.; Li, B. S.*; Tang, B.Z. *Unexpected aggregation induecd circular dichoism, circular polarized luminescence and helical assembly from achiral hexaphenylsilole(HPS), RSC Advances, 2017, 7, 24841
21. Li, H.；Li, B. S.*; Tang, B. Z. * Helicity, assembly, and circularly polarized luminescence of chiralAIEgens Proc. of SPIE，invited keynote paper, 2016，Vol. 9940 99400A-1-99400A-8.
20. Li, H., Xue, S.；H. Su B. Shen, Z. Cheng. J. W. Y. Lam, Kam Sing Wong, H. Wu, Li, B. S.*, Tang B. Z.*, Nanofibers: Click Synthesis, Aggregation-Induced Emission and Chirality, Circularly Polarized Luminescence, and Helical Self-Assembly of a Leucine-Containing Silole (封面论文) Small, 2016,12,6593-6601
19. Li, B. S.*; Wen R.; Xue S.; Shi L.; Tang, Z. Y.; Wang, Z, M.b; Tang, B. Z.* Fabrication of circular polarized luminescent helical fibers from chiral phennanthro[9,10]imidazole derivatives, Mater. Chem. Front, 2017, 1, 646
18. Li,H.; Cheng,J.; Deng,H.; Zhao,E.; Shen,B.; J. W. Y. Lam,; Wong, C.; Wu,K. S.; Li, B. S.*; Tang, B. Z.*, Synthesis, optical properties, and helical self-assembly of a bivalinecontaining tetraphenylethene Sci. Rep. 2016, 6, 19277.
17. Li,H.; Cheng, J.; Deng,H.; Zhao, E.; Shen, B.; J. W. Y. Lam,; Wong, C.; Wu, K. S.; Li, B. S.*; Tang, B. Z.*, Aggregation-induced chirality, circularly polarized luminescence, and helical self-assembly of aleucine-containing AIE luminogen J. Mater. Chem. C. 2015, 3, 2399 – 2404.
16. Li, H.; Cheng, J.; Zhao, Y.; Lam, J. W. Y.; Wong, K. S.; Wu, H.; Li, B. S.*; Tang, B. Z.* L-Valine methyl ester-containing tetraphenylethene: aggregation-induced light emission and circular dichroism, circularly polarised luminescence, and helical self-assembly Mater. Hori.2014, 1, 518-521.
15. Ng, J. C. Y.; Li, H.; Yuan, Q.; Liu, J.; Liu, C.; Fan, X.; Li, B. S.* and Tang, B. Z.* Valine containing silole, synthesis, aggregation induced chirality, luminescence enhancement, chiral polarized luminescence and self-assembled structures J. Mater. Chem. C, 2014, 2, 4615 – 4621.
14. Li, B. S.*; Lam, J. W. Y.; Yu, Z. and Tang, B. Z.Tunable Helical Assemblies of L-Alanine Methyl Ester-Containing Polyphenylacetylene Langmuir, 2012, 28, 5770–5774.
13. Li, B. S.*; Wei, B.; M. C. Goh Direct visalization of the formation of RecA/dsDNA complexes at the single-molecule level Micron, 2012, 43, 1073-1075
12. Li, B. S.; Goh, C.*, Direct Evidence of the Role of ATPγS in the Binding of Single-Stranded Binding Protein (Escherichia coli) and RecA to Single-Stranded DNA Langmuir, 2010, 26, 14755-14758
11. Li, B. S.; Goh, C.* Direct visualization of the formation and structure of RecA/dsDNA complexes Micron, 2010, 41, 227-231.
10. Cheuk, K. K. L.; Li, B. S.; Lam, J. W. Y.; etc. Synthesis, Chain Helicity, Assembling Structure, and Biological Compatibility of Poly(phenylacetylene)s Containing L-Alanine Moieties Macromolecules, 2008, 41, 5997–6005
9. Cheuk, K. K; Lam, J. W. Y; Li, B. S.; Xie, Y. and Tang, B. Z. Decorating Conjugated Polymer Chains with Naturally Occurring Molecules: Synthesis, Solvatochromism, Chain Helicity, and Biological Activity of Sugar-Containing Poly(phenylacetylene)s Macromolecules,2007, 40(8), 2633-2642.
8. Goh, C.*; Li, B. S.Reply to Comment on “Direct and Real-Time Visualization of the Disassembly of a Single RecA-DNA-ATP?S Complex Using AFM Imaging in Fluid”, Nano Lett., 2007, 7, 1110-1111.
7. Li, B. S.; Sattin, B.; Goh, C. Direct and real-time visualization of the disassembly of a single RecA-DNA-ATP gamma S complex using AFM imaging in fluid, Nano Lett., 2006, 6, 1474-1478.
6. Li, C. J.; Guo, Y. G.; Li, B. S.; Wang, C. R.; Wan, L. J.; Bai, C. L. "Template Synthesis of Sc@C82 Nanowires and Nanotubes at Room Temperature" Adv. Mater. 2005, 17(1), 71-73
5. Li, B. S.; Kang, S. Z. etc. Self-assembling of polyacetylene bearing amino acid attachment on mica, in solution and on water surface Langmuir, 2004, 20, 7598-7603.
4. Li, B. S.; Chen, J.; Zhu, C. etc. Formation of vesicular fibers and porous film from chiral oligomers, Langmuir 2004, 24, 2515-2518.
14. Li, B. S.; Cheuk, K. K. L.; Yang, D.; Lam, J. W. Y.; Wan, L. J.; Bai, C.; Tang, B. Z. Self-Assembling of an Amphiphilic Polyacetylene Carrying L-Leucine Pendants:? A Homopolymer Case. Macromolecules2003, 36, 5447-5450.
3. Li, B. S.; Cheuk, K. K. L.; Ling, L.; Chen, J.; Xiao, X.; Bai, C.; Tang, B. Z. Synthesis and Hierarchical Structures of Amphiphilic Polyphenylacetylenes Carrying L-Valine Pendants. Macromolecules2003, 36, 77-85.
2. Li, B. S.; Li, G. P.; Wang, C.; Wang, M.; Wang, D. C.; Bai, C. Structure-Governed Growth Phenomenon of a Trichosanthin Crystal. Langmuir2002, 18, 6723-6726.
1. Li, B. S.; Cheuk, K. K. L.; Salhi, F.; Lam, J. W. Y.; Cha, J. A. K.; Xiao, X.; Bai, C.; Tang, B. Z. Tuning the Chain Helicity and Organizational Morphology of an L-Valine-Containing Polyacetylene by Ph Change. Nano Lett. 2001, 1, 323-328.

论著章节：

1. Li, B. S.; Cheuk, K.K.L.; Chen, J.; Xiao, X.; Bai, C.; Tang, B. Z. “Vesicular and Tubular Nanoassemblies of an Helical Amphiphilic Polyacetylene” In Nano Science and Technology–Novel Structures and Phenomena; Tang, Z. K., Sheng, P., Eds.; Taylor & Francis: London, 2003; Chapter 9, pp 98–104.
2. Li, B. S.; Cheuk, K.K.L.; Chen, J.; Xiao, X.; Bai, C.; Tang, B. Z. “Vesicular and Tubular Nanoassemblies of an Helical Amphiphilic Polyacetylene” in Nano Science and Technology–Novel Structures and Phenomena, Chapter 9
3. Cheuk, K. K. L.; Li, B. S.; Tang, B. Z.“Polyacetylene Nanostructures” In Encyclopedia of Nanoscience and Nanotechnology; Nalwa, H. S., Ed.; American Scientific Publishers: CA, 2004; Vol. 8, pp 703–713 (invited review).
4. Cheuk,K. K. L.; Li, B. S.; Lam, J. W. Y.; Chen, J.; Bai, C.; Tang, B. Z. “Amphiphilic Conjugated Polymers with Tunable Chain Helicity and Organizational Morphology” In Advanced Nanomaterials and Nanodevices; Gao, H., Fuchs, H., Chen, D., Eds.; Institute of Physics Publishing Ltd: Philadelphia, PA, 2003; pp 87–107 (invited paper).
5. Tang, B. Z.; Cheuk, K. K. L.; Salhi, F.; Li, B. S.; Lam, J. W. Y.; Cha,J. A. K.; Xiao, X. D. In Synthetic Macromolecules with Higher Structure order, Khan, I.M., Ed.; American Chemistry Society: ACS Symposium Series 812, Washington, DC, 2001 chapter 10, pp 133-148.

专利
1.李冰石、黄光熙、江玉卿，一种发光材料及其合成方法及应用，申请号：9.X
2.李冰石、黄光熙、江玉卿，发光材料、发光材料的合成方法及应用，申请号：3.4
3.李冰石、黄光熙、夏庆，多重刺激响应变色材料及其制备方法、应用，申请号：9.6
4.李冰石、黄光熙、张洪岩，多重刺激响应变色材料及其制备方法、应用，申请号：2.2
5.李冰石、黄光熙、谢巍巍，多重刺激响应材料及其制备方法与应用，申请号：7.2.


科研项目
1、主持深圳市****基金（2011.6）60万
2、主持国家自然科学青年基金项目（2013.1- 2015.12）25万
3、主持国家自然科学基金面上项目（2016.1- 2019.12）78万
4、核心成员 广东省研究创新群体子课题（2016.1 – 2020.12）300（55）万
5、主持深圳市基础研究项目（2017.5 – 2019.5）30万
6、广东省基础研究项目（2017.1 - 2020.2）10万
7、副组长 深圳大学交叉学科创新团队（2018，12-2022，12）300万
8、广东省教育厅重点项目（2020，1-2022，12）15万


荣誉获奖
?2019年深圳大学化学与工程学院单项教学奖
?2013年深圳市****基金
?2001、2002年中科院化学所青年化学奖