更新日期：2019年3月14日
姓 名 竺传乐 性 别 男
出生年月 1987年11月 籍贯 湖南华容县
民 族 汉族 政治面貌 党员
最后学历 博士研究生 最后学位 理学博士
技术职称 副教授 导师类别 硕导
行政职务Email cechlzhu@scut.edu.cn
工作单位 化学与化工学院 邮政编码 510640
通讯地址 天河区五山路381号
单位电话 **
个人主页 http://www2.scut.edu.cn/ce/2017/0927/c2422a210832/page.htm


个人简介
基于绿色化学理念，通过有机小分子催化不对称合成及过渡金属催化碳氢活化等策略，利用化学键选择性断裂与可控性重组等手段，围绕杂环、小环及含氟分子的高效合成与转化开展研究工作。近年来主持了国家自然科学基金青年项目、国家重点研发计划项目课题等国家级、省部级科研项目8项，发表SCI论文33篇，其中以第一或通讯作者在Angew. Chem. Int. Ed., Org. Lett., Chem. Commun.等上发表SCI研究论文21篇（12篇IF > 5.4），SCI他引350次；申请发明专利8项，授权发明专利4项，出版英文专著1部。
工作经历
2017.4-至今， 华南理工大学化学与化工学院，副教授，硕士生导师；
2015.3-2017.3，华南理工大学化学与化工学院，有机化学，II类博士后，助理研究员；
教育经历
2009.9-2015.1，天津大学，有机化学，博士；
2011.9-2012.7，法国国立应用科学学院鲁昂分院，有机化学，博士交流生；
2005.9-2009.7，天津大学，化学，学士。
获奖、荣誉称号
2011年，法国外交部埃菲尔博士研究生奖学金（全球35人/年）；
2012年，教育部2012年度博士研究生学术新人奖；
2012年，教育部2012年度博士研究生国家奖学金；
2012年，天津大学2012年度优博基金；
2013年，中国航天科技集团一等奖学金；
2018年，广州市2018年度珠江科技新星。
研究领域
碳氢活化、有机氟化学、绿色有机合成化学、催化不对称合成
科研项目
[1] 国家自然科学基金青年项目，主持；
[2] 国家重点研发计划项目课题，主持；
[3] 广东省自然科学基金博士启动项目，主持；
[4] 广州市科技计划项目-珠江科技新星专题，主持；
[5] 中国博士后基金特别资助项目，主持；
[6] 中国博士后基金面上项目（一等），主持；
[7] 制浆造纸国家重点实验室开放基金，主持；
[8] 华南理工大学中央高校面上项目，主持。
发表论文
2019
1.Chuanle Zhu*, Chi Liu, Hao Zeng, Fulin Chen, Huanfeng Jiang*. Transition-Metal Free Selective C(α)-C(β) Bond Cleavage of Trifluoromethyl Ketones with Amidines under Air: Facile Access to 5-Trifluoromethylated Imidazol-4-ones. Org. Chem. Front. 2019, 6, 858.
2.Hao Zeng, Chuanle Zhu*, Huanfeng Jiang*. Single C(sp3)-F Bond Activation in a CF3 Group: Ipso-Defluorooxylation of (Trifluoromethyl)alkenes with Oximes. Org. Lett. 2019, 21, 1130.

2018
3.Chuanle Zhu*, Hao Zeng, Fulin Chen, Zhiyi Yang, Yingying Cai, Huanfeng Jiang*. Intermolecular C(sp3)-H Amination Promoted by Internal Oxidants: Synthesis of Trifluoroacylated Hydrazones. Angew. Chem. Int. Ed. 2018, 57, 17215.
4.Chuanle Zhu, Fulin Chen, Hao Zeng, Chi Liu, Zhiyi Yang, Wanqing Wu, Huanfeng Jiang*. Copper-Catalyzed Unstrained C-C Single Bond Cleavage of Acyclic Oxime Acetates Using Air: An Internal Oxidants Triggered Strategy toward Nitriles and Ketones. J. Org. Chem. 2018, 83, 14713
5.Huanfeng Jiang*, Fulin Chen, Chuanle Zhu*, Rui Zhu, Hao Zeng, Chi Liu, Wanqing Wu. Two C-O Bond Formations on a Carbenic Carbon: Palladium-Catalyzed Coupling of N-Tosylhydrazones and Benzo-1,2-quinones To Construct Benzodioxoles. Org. Lett. 2018, 20, 3166.
6.Chuanle Zhu, Hao Zeng, Fulin Chen, Chi Liu, Rui Zhu, Wanqing Wu, Huanfeng Jiang*. Copper-Catalyzed Coupling of Oxime Acetates and Aryldiazonium salts: an Azide-Free Strategy Toward N-2-Aryl-1,2,3-Triazoles. Org. Chem. Front. 2018, 5, 571.
7.Huanfeng Jiang*, Rui, Zhu, Chuanle Zhu*, Fulin Chen, Wanqing Wu. Nucleophilic trifluoromethylthiolation of bromoalkynones with AgSCF3: C(sp)-SCF3 bond formation towards ynonyl trifluoromethyl sulfides. Org. Biomol. Chem. 2018, 16, 1646.
8.Wei Huang, Chuanle Zhu, Minke Li, Wanqing Wu, Zhengchao Tu*, Huanfeng Jiang*. TBAI or KI-Promoted Oxidative Coupling of Enamines and N-Tosylhydrazine: An Unconventional Method toward 1,5-and 1,4,5-Substituted 1,2,3-Triazoles. Adv. Synth. Catal. 2018, 360, 3117.

2017
9.Chuanle Zhu, Rui Zhu, Hao Zeng, Fulin Chen, Chi Liu, Wanqing Wu, Huanfeng Jiang*. Copper-Catalyzed Csp3-H/Csp3-H Cross-Dehydrogenative Coupling with Internal Oxidants: Synthesis of 2-Trifluoromethyl Dihydropyrro-2-ols, Angew. Chem. Int. Ed. 2017, 56, 13324-13328.
10.Chuanle Zhu, Rui Zhu, Pengquan Chen, Wanqing Wu*, Huanfeng Jiang*. Carbonyl Ylides Derived from Palladium Carbenes: The Impressive Fluorine Effect, Adv. Synth. Catal. 2017, 359, 3154.
11.Chuanle Zhu, Pengquan Chen, Rui, Zhu, Guangbin Jiang, Zhiming Lin, Wanqing Wu*, Huanfeng Jiang*. Conversion of Triple Bonds into Single Bonds in a Domino Carbopalladation with Norbornene, Chem. Asian J. 2017, 12, 2991.
12.Pengquan Chen, Chuanle Zhu*, Rui Zhu, Wanqing Wu, Huanfeng Jiang*. MnO2-Promoted Oxidative Radical Sulfonylation of Haloalkynes with Sulfonyl Hydrazides: C(sp)-S Bond Formation towards Alkynyl Sulfones, Chem. Asian J. 2017, 12, 1875.
13.Chuanle Zhu, Pengquan Chen, Rui Zhu, Zhiming Lin, Wanqing Wu*, Huanfeng Jiang*. C=N Bond Formation via Palladium-Catalyzed Carbene Insertion into N=N Bonds: Inhibiting the General 1,2-Migration Process of Ylide Intermediates. Chem. Commun. 2017, 53, 2697.
14.Guangbin Jiang, Chuanle Zhu, Jianxiao Li, Wanqing Wu*, Huanfeng Jiang*. Silver-Catalyzed Regio- and Stereoselective Thiocyanation of Haloalkynes: Access to (Z)-Vinyl Thiocyanates, Adv. Synth. Catal. 2017, 359, 1208.
15.Guangbin Jiang, Jianxiao Li, Chuanle Zhu, Wanqing Wu*, Huanfeng Jiang*. Palladium-Catalyzed Sequential Nucleophilic Addition/Oxidative Annulation of Bromoalkynes with Benzoic Acids To Construct Functionalized Isocoumarins, Org. Lett. 2017, 19, 4440.
16.Jianhua Liao, Lianfeng Fan, Wei Guo, Zhenming Zhang, Jiawei Li, Chuanle Zhu, Yanwei Ren, Wanqing Wu*, Huanfeng Jiang*. Palladium-Catalyzed Fluoroalkylative Cyclization of Olefins, Org. Lett. 2017, 19, 1008.
17.Yubing Huang, Yue Yu, Zhongzhi Zhu, Chuanle Zhu, Jinghe Chen, Xianwei Li, Wanqing Wu*, Huanfeng Jiang*. Copper-Catalyzed Cyanation of N-Tosylhydrazones with Thiocyanate Salt as the “CN” Source, J. Org. Chem. 2017, 82, 7621.
18.Jiangwen Peng, Yan Gao, Chuanle Zhu, Bifu Liu, Yinlan Gao, Miao Hu, Wanqing Wu, Huanfeng Jiang*. Synthesis of Polysubstituted 3-Amino Pyrroles via Palladium-Catalyzed Multicomponent Reaction, J. Org. Chem. 2017, 82, 3581.
19.Pengquan Chen#, Chuanle Zhu#, Rui Zhu, Zhiming Lin, Wanqing Wu*, Huanfeng Jiang*. Synthesis of 3-Azabicyclo[3.1.0]hexane Derivatives via Palladium-Catalyzed Cyclopropanation of Maleimides with N-Tosylhydrazones: Practical and Facile Access to CP-866,087. Org. Biomol. Chem. 2017, 15, 1228 (equal contribution).

2016
20.Huanfeng Jiang, Chuanle Zhu, Wanqing Wu. Haloalkyne Chemistry, Springer, 2016 .
21.Chuanle Zhu, Pengquan Chen, Wanqing Wu*, Chaorong Qi, Yanwei Ren, Huanfeng Jiang*. Transition-Metal-Free Diastereoselective Epoxidation of Trifluoromethylketones with N-Tosylhydrazones: Access to Tetrasubstituted Trifluoromethylated Oxiranes. Org. Lett. 2016, 18, 4008.
22.Chuanle Zhu, Jiawei Li, Pengquan Chen, Wanqing Wu*, Yanwei Ren, Huanfeng Jiang*. Transition-Metal-Free Cyclopropanation of 2-Aminoacrylates with N-Tosylhydrazones: A General Route to Cyclopropane α-Amino Acid with Contiguous Quaternary Carbon Centers. Org. Lett. 2016, 18, 1470.
23.Yue Ye, Songjian Yi, Chuanle Zhu, Weigao Hu, Bingjie Gao, Yang Chen, Wanqing Wu*, Huanfeng Jiang*. Csp3-P versus Csp2-P Bond Formation: Catalyst-Controlled Highly Regioselective Tandem Reaction of Ene-Yne-Ketones with H-Phosphonates, Org. Lett. 2016, 18, 400.
24.Yubing Huang, Xianwei Li, Yue Yu, Chuanle Zhu, Wanqing Wu, Huanfeng Jiang*. Copper-Mediated [3 + 2] Oxidative Cyclization Reaction of N-Tosylhydrazones and β-Ketoesters: Synthesis of 2,3,5- Trisubstituted Furans, J. Org. Chem. 2016, 81, 5014.
25.Chuanle Zhu, Jun-An Ma*, Dominique Cahard*. Trifluorodiazoethane (CF3CHN2) in the Uncatalyzed Cyclopropanation of 3-Arylmethylenebenzofuran-2(3H)-one. Asian J. Org. Chem. 2016, 5, 66.

Before 2015
26.Chuanle Zhu#, Lijun Yang#, Shen, Li, Yan Zheng, Jun-An Ma*. Brine-Stabilized 2,2,2-Trifluorodiazoethane and Its Application in the Synthesis of CF3-Substituted Cyclopropane α-Amino Acids. Org. Lett. 2015, 17, 3442 (equal contribution).
27.Chuanle Zhu, Mayaka Maeno, Fa-Guang Zhang, Taiki Shigehiro, Takumi Kagawa, Kosuke Kawada, Norio Shibata*, Jun-An Ma*, and Dominique Cahard*. Chiral N-Fluorodibenzenesulfonimide Analogues for Enantioselective Electrophilic Fluorination and Oxidative Fluorination. Eur. J. Org. Chem. 2013, 69, 6501.
28.Chuanle Zhu, Xiao-Yun Fu, Ai-Jia Wei, Dominique Cahard*, Jun-An Ma*. P-Spiro Phosphonium Salts Catalyzed Asymmetric Fluorination of 3-Substituted Benzofuran-2-(3H)-ones. J. Fluorine Chem. 2013, 150, 60.
29.Chuanle Zhu, Li-Jun Yang, Jing Nie, Yan Zheng, Jun-An Ma*. Organocatalytic Asymmetric Branching Sequence of MBH Carbonates: Access to Chiral Benzofuran-2(3H)-one Derivatives with Three Stereocenters. Chin. J. Chem. 2012, 30, 2693.
30.Chuanle Zhu, Fa-Guang Zhang, Wei Meng, Jing Nie, Dominique Cahard, Jun-An Ma*. Enantioselective Base-Free Electrophilic Amination of Benzofuran-2(3H)-ones: Catalysis by Binol-Derived P-Spiro Quaternary Phosphonium Salts. Angew. Chem. Int. Ed. 2011, 50, 5869.
31.Lian Wang, Wei Meng, Chuanle Zhu, Yan Zheng, Jing Nie, Jun-An Ma*. The Long-Arm Effect: Influence of Axially Chiral Phosphoramidite Ligands on the Diastereo- and Enantioselectivity of the Tandem 1,4-Addition/Fluorination, Angew. Chem. Int. Ed. 2011, 50, 9442.
32.Hai Ma, Kun Liu, Faguang Zhang, Chuanle Zhu, Jing Nie, Jun-An Ma. Chiral Bifunctional Thiourea-Catalyzed Enantioselective Michael Addition of Ketones to Nitrodienes, J. Org. Chem. 2010, 75, 1402.
出版专著和教材
Huanfeng Jiang, Chuanle Zhu, Wanqing Wu. Haloalkyne Chemistry; Springer: Verlag GmbH Berlin Heidelberg, 2016.
科研创新
[1] 江焕峰，竺传乐，伍婉卿；一种含连续季碳中心环丙烷α-氨基酸衍生物及合成方法；专利授权号：ZL**9.X
[2] 江焕峰，竺传乐，伍婉卿，陈鹏全；一种含三氟甲基取代连续季碳中心环氧丙烷衍生物及合成方法；专利授权号：ZL**2.5
[3] 江焕峰，竺传乐，伍婉卿，陈鹏全；一种含N,N-二酰胺基取代腙衍生物及合成方法；专利授权号：ZL**3.4
[4] 马军安，竺传乐，崔汉峰，聂晶，王腾；含联萘轴手性螺环季膦盐相转移催化剂及其制备方法，专利授权号：ZL**9.3
[5] 江焕峰，陈鹏全，竺传乐；一种氮杂五并三环药物分子中间体的合成方法；专利授权号：ZL**3.3
[6] 江焕峰，竺传乐；一种构建N-2-芳基取代-1,2,3-三氮唑的方法；专利申请号：**7.6
[7] 江焕峰，竺传乐；一种三氟甲基修饰Ab-42抑制剂结构类似物的合成方法；专利申请号：**9.7
[8] 伍婉卿，林芝铭，竺传乐；含连续季碳中心环丙烷氨基磷酸酯类化合物的合成方法；申请专利号：**2.0
教学活动
讲授本科生《有机化学实验》
指导学生情况
1、曾浩（2018级硕士）