所系名称
中国科学院南海海洋研究所，中国科学院热带海洋生物资源与生态重点实验室
性别
男
专业名称
海洋生物学
技术职务
副研究员
行政职务

Mail地址
wangjunfeng@scsio.ac.cn
指导博士生总数
0
指导硕士生总数
0
通讯地址
广州新港新路164号
目前博士生数
0
目前硕士生数
0
邮政编码
510301
研究方向
海洋天然药物化学、海洋微生物代谢产物潜能挖掘和海洋微生物源药物先导化合物发现。

研究工作
主要聚焦于从海洋特境微生物资源中发掘药理活性成分和药物先导化合物，近年来分离鉴定海洋微生物来源天然产物500多个，其中新结构化合物285个，其中新颖骨架的6个/类，筛选发现具有抗肿瘤、抗炎、抗病毒、抗菌活性的天然产物120个。近五年主持国家自然科学基金面上和青年项目，广东省科技计划等项目，入选广州市“珠江科技新星人才”计划。研究成果在Organic Letters和Journal of Natural Products等国际知名学术刊物上。
获奖情况
1.广州市“珠江科技新星”（2017）
指导研究生情况

个人简介
工作经历
2012.06-2016.12：中科院南海海洋研究所，助理研究员
2016.12-至今：中科院南海海洋研究所，副研究员
2019.3-2020.3:加利福尼亚大学洛杉矶分校，访问学者
教育背景
2002.09-2006.06：青岛科技大学化学，学士
2006.09-2009.06：青岛科技大学有机化学，硕士
2009.09-2012.06：中国海洋大学药物化学，博士

科研成果
论文发表（第一或通讯作者）
31.Guo C, Wang P, Lin X, Salendra L, Kong F, Liao S, Yang B, Zhou X,Wang J*, Liu Y*.Phloroglucinol heterodimers and bis-indolyl alkaloids from the Sponge-Derived FungusAspergillussp. SCSIO 41018.Org Chem Front,2019, 6, 3053-3059 (Front Cover Article)
30. Liu N, Peng S, Yang J, Cong Z, Lin X, Liao S, Yang B, Zhou X, Zhou X, Liu Y*,Wang J*.Structurally diverse sesquiterpenoids and polyketides from a sponge-associated fungusAspergillus sydowiiSCSIO41301.Fitoterapia,2019, 135, 27–32.
29. Guo C, Lin X, Liao S, Yang B, Zhou X, Yang X, Tian X,Wang J*, Liu Y.*Two new aromatic polyketides from a deep-sea fungusPenicilliumsp. SCSIO 06720.Nat Prod Res,2019, doi:10.1080/**.2018.**.
28.Cong Z, Huang X*, Liu Y, Liu Y, Wang P, Liao S, Yang B, Zhou X, Huang D,Wang J*.Cytotoxic anthracycline and antibacterial tirandamycin analoguesfrom a marine-derivedStreptomycessp. SCSIO 41399.J Antibiot,2019, 72: 45–49.
27. Pang X, Cai G, Lin X, Salendra L, Zhou X, Yang B, Wang J,Wang J*, Xu S*, Liu Y*.New Alkaloids and Polyketides from the Marine Sponge-Derived FungusPenicilliumsp. SCSIO 41015.Mar. Drugs,2019, 17, 398.
26.Wang J, Qing L, Zhao B, Cai L, Zhong Z, Liu Y, Zhou X*.Crotonols A and B, two rare tigliane diterpenoid derivatives against K562 cells fromCroton tiglium.Org Biomol Chem,2019, 17(1): 195–202.
25.Wang J, Cong Z, Huang X, Hou C, Chen W, Tu Z, Huang D, Liu Y*.Soliseptide A, acyclic hexapeptide possessing piperazic acid groups from Streptomyces solisilvaeHNM30702.Org Lett,2018, 20(5): 1371–1374.
24.Pang X, Lin X, Yang J, Zhou X, Yang B,Wang J*, Liu Y*.Spiro-Phthalides and isocoumarins isolated from the marine-sponge-derived fungusSetosphaeriasp. SCSIO41009.J Nat Prod,2018, 81(8), 1860？1868.(Top 20 Most Read Articles in August, 2018)
23.Pang X, Lin X, Wang P, Zhou X, Yang B,Wang J*, Liu Y*.Perylenequione derivatives with anticancer activities isolated from the marine sponge-derived fungus,Alternariasp. SCSIO41014.Mar. Drugs,2018, 16(8), 280.
22.Wang J*, Zhou L, Chen S, Yang B, Liao S, Kong F, Lin X, Wang F, Zhou X, Liu Y*.New chlorinated diphenyl ethers and xanthones from a deep-sea-derived fungusPenicillium chrysogenumSCSIO 41001.Fitoterapia,2018, 125, 49–54.
21.Pang X, Lin X,Wang J*, Liang R, Tian Y, Salendra L, Luo X, Zhou X, Yang B, Tu Z, Liu Y*.Three new highly oxygenated sterols and one new dihydroisocoumarin from the marine sponge-derived fungusCladosporiumsp. SCSIO41007.Steroids,2018, 129, 41–46.
20.Wang J, He W, Kong F, Tian T, Wang P, Zhou X*, Liu Y*.Ochracenes A？I, Humulane-Derived Sesquiterpenoids from the Antarctic FungusAspergillus ochraceopetaliformis.J Nat Prod,2017, 80(6): 1725–1733. (Highlighted by Natural Products Reports)
19.Wang J, Liang R, Liao S, Yang B, Tu Z, Lin X, Wang B, Liu Y*.Vaccinols J–S, ten new salicyloid derivatives from the marine mangrove-derived endophytic fungusPestalotiopsis vaccinii.Fitoterapia,2017, 120: 164–170.
18.He W, Zhou X, Qin X, Mai Y, Lin X, Liao S, Yang B, Zhang T, Tu Z,Wang J*, Liu Y*.Quinone/hydroquinone meroterpenoids with antitubercular and cytotoxic activities produced by the sponge-derivedfungusGliomastixsp. ZSDS1-F7.Nat Prod Res,2017, 31(5): 604–609.
17.Wang J, Wei X, Qin X, Tian X, Liao L, Li K, Zhou X, Yang X, Wang F, Tu Z, Chen B, Liu Y*.Antiviral Merosesquiterpenoids Produced by the Antarctic FungusAspergillus ochraceopetaliformisSCSIO 05702,J Nat Prod,2016, 79(1): 59–65. (Highlighted by Natural Products Reports)
16.Wang J, He W, Huang X, Tian X, Liao S, Yang B, Wang F, Zhou X, Liu Y*.Antifungal New Oxepine-Containing Alkaloids and Xanthones from the Deep-Sea-Derived FungusAspergillus versicolorSCSIO 05879,J Agric Food Chem,2016, 64(16): 2910–2916.
15.Wang J, Qin X, Chen Z, Ju Z, He W, Tan Y, Zhou X, Tu Z, Lu F*, Liu Y*.Two new anthraquinones with antiviral activities from the barks ofMorinda citrifolia(Noni),Phytochem Lett,2016, 15: 13–15.
14.Zhao B^#, Peng S^#, He W, Liu Y,Wang J*, Zhou X*.Antitubercular and cytotoxic tigliane-type diterpenoidsfromCroton tiglium,Bioorg Med Chem Lett,2016, 26(20): 4996–4999.
13.Xu G^#, Wang Z^#, Zhao B, Liu N, Yang S, Liu Y,Wang J*, Zhou X*.Saniculamins A and B, two new flavonoids fromSanicula lamelligeraHance inhibiting LPS-inducednitric oxide release,Phytochem Lett,2016, 18: 35–38.
12.Wang J, Wei X, Qin X, Lin X, Zhou X, Liao S, Yang B, Liu J, Tu Z, Liu Y*.Arthpyrones A–C, pyridine alkaloids from a sponge-derivied fungusArthrinium arundinisZSDS1-F3.Org Lett,2015, 17(3): 656–659.(ACS Editors' Choice, Highlighted by Natural Products Reports)
11.Wang J, He W, Qin X, Wei X, Tian X, Liao L, Liao S, Yang B, Tu Z, Chen B, Wang F, Zhou X*, Liu Y*.Three new indolyl diketopiperazine metabolites from the antarctic soil-derived fungusPenicilliumsp. SCSIO 05705,RSC Adv,2015, 5(84): 68736–68742.
10.Wang J, Wang Z, Ju Z, Wan J, Liao S, Lin X, Zhang T, Zhou X, Chen H, Tu Z*, Liu Y*.Cytotoxic cytochalasins from marine-derived fungusArthrinium arundinis.Planta Med,2015, 81(2): 160–166.
9.Wang J, He W, Zhang X, Zhao B, Liu Y, Zhou X*.Dicarabrol, a new dimer icsesquiterpene fromCarpesium abrotaoidesL.Bioorg Med Chem Lett,2015, 25(19): 4082–4084.
8.Wang J^#, Yang S^#, Liu Y, Li D, He W, Zhang X, Liu Y*, Zhou X*.Five new phorbol esters with cytotoxic and selective anti-inflammatory activities fromCroton tiglium.Bioorg Med Chem Lett,2015, 25(9): 1986–1989.
7.Yang S^#, Liu Y^#,Wang J*, Wang Y, Pan W, Sheng W, Cai R, Zhou X*.Isoquinoline alkaloids fromZanthoxylum simulansand their biological evaluation,J Antibiot,2015, 68(4): 289–292.
6.Wang J, Wei X, Qin X, Chen H, Lin X, Zhang T, Yang X, Liao S, Yang B, Liu J, Zhou X, Tu Z*, Liu Y*.Two new prenylated phenols from endogenous fungusPestalotiopsis vacciniiof mangrove plantKandelia candel(L.) Druce.Phytochem Lett,2015, 12: 59–62.
5.Wang J^#, Qin X^#, Xu F, Zhang T, Liao S, Lin X, Yang B, Liu J, Wang L, Tu Z*, Liu Y*.Tetramic acid derivatives and polyphenols from sponge-derived fungus and their biological evaluation.Nat Prod Res,2015, 29(18): 1761–1765.
4.Wang J, Wei X, Lu X, Xu F, Wan J, Lin X, Zhou X, Liao S, Yang B, Tu Z, Liu Y*.Eight new polyketide metabolites from the fungusPestalotiopsis vacciniiendogenous with the mangrove plantKandelia candel(L.) Druce.Tetrahedron,2014, 70(51): 9695–9701.
3.Wang J, Deng Y, Yang S, Liu Y, Wang Y, Pan W, Zhou X*.Characterization and biological evaluation of six new dimericlignans with an unusual α,β-unsaturated ketone motif fromZanthoxylum simulans,Bioorg Med Chem Lett,2014, 24(19): 4667–4671.
2.Wang J, Xu F, Wang Z, Lu X, Wan J, Yang B, Zhou X, Zhang T, Tu Z, Liu Y*.A new naphthalene glycoside from the sponge-derived fungusArthriniumsp. ZSDS1-F3.Nat Prod Res,2014, 28(14): 1070–1074.
1.Wang J^#, Lin X^#, Qin C, Liao S, Wan J, Zhang T, Liu J, Fredimoses M, Chen H, Yang B, Zhou X, Yang X, Tu Z*, Liu Y*.Antimicrobial and antiviral sesquiterpenoids from sponge-associated fungus,Aspergillus sydowiiZSDS1-F6.J Antibiot,2014, 67(8): 581–583.
授权发明专利
1. 王俊锋, 刘永宏, 周雪峰, 廖升荣, 杨献文, 杨斌, 林秀萍, 刘娟。吡啶酮生物碱类化合物及其制备方法和在制备抗肿瘤药物中的应用。专利号:：ZL0.4.
2. 王俊锋, 刘永宏, 周雪峰, 廖升荣, 杨献文, 杨斌, 林秀萍, 刘娟。生物碱类化合物在制抗肠道病毒及乙酰胆碱酯酶抑制剂药物中的应用。专利号：ZL5.4.
3. 王俊锋, 贺卫军, 田新朋, 刘永宏。一种α-吡喃酮混源萜及其制备方法和应用。专利号：ZL5.2.
4. 王俊锋, 贺卫军, 黄小龙, 田新朋, 刘永宏。抗生素Versicoloids A 和B及其制备方法和在制备抗植物病原菌药物中的应用。专利号：ZL9.9.
5. 王俊锋，贺卫军，黄小龙，田新朋，刘永宏。海洋曲霉SCSIO 05879制备Versicoloids A和B及在抗胶孢炭疽菌药物中的应用. 专利号：ZL 6.2.
6. 王俊锋，孔凡栋，田新朋，周小江，刘永宏。一类新颖结构倍半萜化合物及其在制备抗炎药物中的应用。专利号:ZL9.5