个人简介

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职称：教授
学科专业：病理生物学
研究方向：
1. 病毒变异、进化和起源
2. 艾滋病和其它重大传染病疫苗
3. 病毒致病机理
4. 抗病毒药物和耐药机制
5. 新发突发重大传染病
个人简介：高峰，教授，1961年2月出生，暨南大学教授，博士生导师，国家高层次人才引进计划创新人才，广东省珠江杰出人才。高峰教授是世界著名艾滋病病毒学研究专家，在艾滋病及相关领域研究30年并一直处于世界领先地位。高峰教授对HIV起源，病毒变异进化，致病性、耐药性、适应性、免疫逃逸，广谱中和抗体产生机制和疫苗等研究领域均做出重要贡献。已发表学术论文180余篇，应邀综述和专著章节14篇。在“细胞”、“自然”、“科学”和“新英格兰医学”等世界顶级杂志发表15篇论文。根据谷歌****数据库检索发表文章到目前已被引用>25000次。谷歌****H因子为74。获得美国专利6项。多次应邀在国际会议做邀请报告，主办或协助举办国际艾滋病会议。

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学习经历

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1984.09-1987.12，中国预防医学科学院 ，获医学硕士学位；
1978.09-1984.07，哈尔滨医学院，获医学学士学位。

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工作经历

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2020.10-至今，暨南大学基础医学与公共卫生学院，教授；
2020.10-至今，美国杜克大学医学中心，荣誉教授；
2011.12-至今，吉林大学，教授；
2009.10-2020.09，美国杜克大学医学中心，教授；
2006.10-2009.08，美国杜克大学医学中心，副教授；
2001.10-2006.09，美国杜克大学医学中心，研究副教授；
1999.06-2001.09，美国阿拉巴马伯明翰大学艾滋病中心，副科学家；
1998.07-2001.09，美国阿拉巴马伯明翰大学，研究助理教授；
1993.07-1998.06，美国阿拉巴马伯明翰大学，研究指导；
1992.07-1993.06，美国阿拉巴马伯明翰大学，研究助理；
1990.01-1992.06，美国阿拉巴马伯明翰大学，博士后；
1988.01-1989.12，中国预防医学科学院病毒所，助理研究员

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主要论文

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1. Bhavna Hora, Naila Gulzar, Yue Chen, Konstantinos Karagiannis, Fangping Cai, Chang Su, Krista Smith, Vahan Simonyan, Sharaf Ali Shah, Manzoor Ahmed, Ana M. Sanchez, Mars Stone, Myron S. Cohen, Thomas N. Denny, Raja Mazumder, Feng Gao. Streamlined Subpopulation, Subtype, and Recombination Analysis of HIV-1 Half-Genome Sequences Generated by High-Throughput Sequencing. mSphere. 2020 5(5): e00551-20. PMCID: PMC**
2. Xiaojun Li, Elena E. Giorgi, Manukumar Honnayakanahalli Marichann, Brian Foley, Chuan Xiao, Xiang-Peng Kong, Yue Chen, Bette Korber and Feng Gao. Emergence of SARS-CoV-2 through Recombination and Strong Purifying Selection. Science Advances. 2020 6(27): eabb9153.
3. Xiao C, Li X, Liu S, Sang Y, Gao SJ, Gao F. HIV-1 did not contribute to the 2019-nCoV genome. Emerg Microbes Infect. 2020 9(1):378-381. (*Co-corresponding authors) PMID: **
4. Gao N, Gai Y, Meng L, Wang C, Zhang X, Wang W, Qin C, Yu X*, Gao F*. Development of Antibodies with Broad Neutralization Specificities against HIV-1 after Long Term SHIV Infection in Macaques. Viruses. 2020 12(2):163. (*Co-corresponding authors) PMID: ** PMCID: PMC**
5. Blasi M, Stadtler H, Chang J, Hemmersbach-Miller M, Wyatt C, Klotman P, Gao F, Wolfe C, Klotman M. Detection of Donor's HIV Strain in HIV-Positive Kidney-Transplant Recipient. N Engl J Med. 2020. 382(2):195-197. PMID: **
6. Song H, Giorgi EE, Ganusov VV, Cai F, Athreya G, Yoon H, Carja O, Hora B, Hraber P, Romero-Severson E, Jiang C, Li X, Wang S, Li H, Salazar-Gonzalez JF, Salazar MG, Goonetilleke N, Keele BF, Montefiori DC, Cohen MS, Shaw GM, Hahn BH, McMichael AJ, Haynes BF, Korber B, Bhattacharya T, Gao F. Tracking HIV-1 recombination to resolve its contribution to HIV-1 evolution in natural infection. Nat Commun. 9(1):1928. 2018. PMID: **; PMC**.
7. Bonsignori M, Chen L, Zhou T, Gao F, Sheng Z, Joyce GM, Ozorowski G, Schramm C, Wiehe K, Alam MS, Bradley T, Hwang KK, Luo K, Lu X, Mangiapani M, Iyengar S, Gladden M, Kumar A, Song H, Parks RJ, Acharya P, Bailer RT, Cao A, Chuang GY, Druz A, Georgiev IS, Louder MK, Wu X, Zhang B, Zheng A, Montefiori DC, Michael A. Moody MA, Shaw GM, Hahn BH, Kelsoe G, Hraber P, Korber BT, Boyd S, Fire AZ, Kepler TB, Mascola JR, Shapiro L, Ward A, Liao HX, Kwong PD, Haynes BF. Maturation Pathway from Germline to Broad HIV-1 Neutralizer of a CD4-Mimicking Antibody. Cell. 165(2):449-63, 2016. PMID: **
8. Moody MA*, Gao F*, Gurley TC, Amos JD, Kumar A, Hora B, Marshall DJ, Whitesides JF, Xia SM, Parks R, Lloyd KE, Hwang KK, Lu X, Bonsignori M, Finzi A, Vandergrift NA, Alam SM, Ferrari G, Shen X, Tomaras GD, Kamanga G, Cohen MS, Sam NE, Kapiga S, Gray ES, Tumba NL, Morris L, Zolla-Pazner S, Gorny MK, Mascola JR, Hahn BH, Shaw GM, Sodroski JG, Liao HX, Montefiori DC, Hraber PT, Korber BT, Haynes BF*. Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses. Cell Host Microbe. 18(3):354-62. 2015. (*Co-corresponding authors) PMID: **; PMCID: PMC**
9. Williams WB, Liao HX, Moody MA, Kepler TB, Alam SM, Gao F, Wiehe K, Trama AM, Jones K, Zhang R, Song H, Marshall DJ, Whitesides JF, Sawatzki K, Hua A, Liu P, Tay MZ, Seaton KE, Shen X, Foulger A, Lloyd KE, Parks R, Pollara J, Ferrari G, Yu JS, Vandergrift N, Montefiori DC, Sobieszczyk ME, Hammer S, Karuna S, Gilbert P, Grove D, Grunenberg N, McElrath MJ, Mascola JR, Koup RA, Corey L, Nabel GJ, Morgan C, Churchyard G, Maenza J, Keefer M, Graham BS, Baden LR, Tomaras GD, Haynes BF. HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies. Science. 349(6249):aab1253. 2015. PMID: **; PMCID: PMC**
10. Gao F*, Bonsignori M, Liao HX, Kumar A, Xia SM, Lu X, Cai F, Hwang KK, Song H, Zhou T, Lynch RM, Alam SM, Moody MA, Ferrari G, Berrong M, Kelsoe G, Shaw GM, Hahn BH, Montefiori DC, Kamanga G, Cohen MS, Hraber P, Kwong PD, Korber BT, Mascola JR, Kepler TB, Haynes BF*. Cooperation of B Cell Lineages in Induction of HIV-1-Broadly Neutralizing Antibodies. Cell. 158(3):481-91. 2014. (*Co-corresponding authors) PMID: **; PMCID: PMC**
11. Liao HX*, Lynch R*, Zhou T*, Gao F*, Alam SM, Boyd SD, Fire AZ, Roskin KM, Schramm CA, Zhang Z, Zhu J, Shapiro L; NISC Comparative Sequencing Program, Becker J, Benjamin B, Blakesley R, Bouffard G, Brooks S, Coleman H, Dekhtyar M, Gregory M, Guan X, Gupta J, Han J, Hargrove A, Ho SL, Johnson T, Legaspi R, Lovett S, Maduro Q, Masiello C, Maskeri B, McDowell J, Montemayor C, Mullikin J, Park M, Riebow N, Schandler K, Schmidt B, Sison C, Stantripop M, Thomas J, Thomas P, Vemulapalli M, Young A, Mullikin JC, Gnanakaran S, Hraber P, Wiehe K, Kelsoe G, Yang G, Xia SM, Montefiori DC, Parks R, Lloyd KE, Scearce RM, Soderberg KA, Cohen M, Kamanga G, Louder MK, Tran LM, Chen Y, Cai F, Chen S, Moquin S, Du X, Joyce MG, Srivatsan S, Zhang B, Zheng A, Shaw GM, Hahn BH, Kepler TB, Korber BT, Kwong PD, Mascola JR, Haynes BF. Co-evolution of a broadly neutralizing HIV-1 antibody and founder virus. Nature. 496:469-76. 2013. (*Equal contribution) PMID: **; PMCID: PMC**
12. Keele BF, Giorgi EE, Salazar-Gonzalez JF, Decker JM, Pham KT, Salazar MG, Sun C, Grayson T, Wang S, Li H, Wei X, Jiang C, Kirchherr JL, Gao F, Anderson JA, Ping LH, Swanstrom R, Tomaras GD, Blattner WA, Goepfert PA, Kilby JM, Saag MS, Delwart EL, Busch MP, Cohen MS, Montefiori DC, Haynes BF, Gaschen B, Athreya GS, Lee HY, Wood N, Seoighe C, Perelson AS, Bhattacharya T, Korber BT, Hahn BH, Shaw GM. Identification and characterization of transmitted and early founder virus envelopes in primary HIV-1 infection. Proc Natl Acad Sci U S A. 105:7552-7. 2008. PMID: **; PMCID: PMC**
13. Cai F, Chen H, Hicks CB, Bartlett JA, Zhu J and Gao F. Detection of minor drug-resistance populations by parallel allele-specific sequencing. Nat. Methods. 4:123-125. 2007. PMID: **; PubMed PMID: **
14. Weaver EA, Lu Z, Camacho ZT, Moukdar F, Liao H-X, Ma B-J, Muldoon M, Theiler J, Nabel GJ, Letvin NL, Korber BT, Hahn BH, Haynes BF and Gao F. Cross-subtype T Cell Immune Responses induced by an HIV-1 Group M Consensus Env Immunogen. J. Virol. 80:6745-6756. 2006. PMID: **; PMCID: PMC**
15. Switzer WM, Salemi M, Shanmugam V, Gao F, Cong ME, Kuiken C, Bhullar V, Beer BE, Vallet D, Gautier-Hion A, Tooze Z, Villinger F, Holmes EC and Heneine W. Ancient co-speciation of simian foamy viruses and primates. Nature 17;434(7031):376-80. 2005. PMID: **
16. Bailes E, Gao F, Bibollet-Ruche F, Courgnaud V, Peeters M, Marx PA, Hahn BH, Sharp PM. Hybrid origin of SIV in chimpanzees. Science 300:1713, 2003. PMID: **
17. Gao F, Bhattacharya T, Gaschen, B, Taylor J, Moore JP, Novitsky V, Yusim K, Lang D, Foley B, Beddows S, Alam M, Haynes B, Hahn BH, and Korber B. Consensus and Ancestral State HIV Vaccines (Letter). Science 299:1517-1518. 2003.
18. Gaschen B, Taylor J, Yusim K, Foley B, Gao F, Lang D, Novitsky V, Haynes B, Hahn BH, Bhattacharya T, Korber B. Diversity considerations in HIV-1 vaccine selection. Science 296:2354-60, 2002. PMID: **
19. Santiago M, Rodenburg C, Kamenya S, Bibollet-Ruche F, Gao F, Bailes E, Meleth S, Soong S, Kilby J, Moldoveanu Z, Fahey B, Muller M, Ayouba A, Nerrienet E, McClure H, Heeney J, Pusey A, Collins A, Boesch C, Wrangham R, Goodall J, Sharp P, Shaw GM and Hahn BH. SIVcpz in wild chimpanzees. Science, 295:465, 2002. PMID: **
20. Korber B, Bhattacharya T, Theiler J, Gupta R, Lapedes A, Hahn BH, Gao F, Muldoon M, Wolinsky S. Search for the Origin of HIV and AIDS. Science 289: 1140-1141, 2000.
21. Korber B, Muldoon M, Theiler J, Gao F, Gupta R, Lapedes A, Hahn BH, Wolinsky S and Bhattacharya T. Timing the ancestor of the HIV-1 Pandemic strains. Science 288:1789-1796, 2000. PMID: **
22. Robertson DL, Anderson J, Bradac JA, Carr JK, Foley B, Gao F, Hahn BH, Kuiken C, Learn GH, Leitner T, McCutchan F, Osmanov S, Peeters M, Pieniaze D, Salminen M, Wolinsky S, and Korber B. HIV-1 Nomenclature Proposal. Science 288:55, 2000. PMID: **
23. Gao F, Bailes E, Robertson DL, Chen Y, Rodenburg CM, Michael SF, Cummins LB, Arthur LO, Peeters M, Shaw GM, Sharp PM and Hahn BH. Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytes. Nature 397:436-441, 1999. PMID: **
24. Gao F, Yue L, White AT, Pappas PG, Barchue J, Hanson AP, Greene BM, Sharp PM, Shaw GM and Hahn BH. Human infection by genetically divers SIVSM related HIV-2 in West Africa. Nature 358:495-499, 1992. PMID: **.

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学术著作

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1. 高峰，第五章-HIV2及SIV的病毒学及生物学，《艾滋病毒感染与艾滋病》，人民卫生出版社，68页-88页，1999年。
2. 高峰，第二章-HIV感染的分子流行病学，《艾滋病毒感染与艾滋病》，人民卫生出版社，13页-32页，1999年。

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学术兼职

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专业会员：
1、中国实验动物学会免疫与细胞治疗专业委员会 副主任委员
2、中国性病艾滋病防治协会艾滋病病毒专业委员会 副主任委员
3、中国性病艾滋病防治协会基础研究专业委员会 常务委员
4、天津市滨海新区艾滋病疫苗研究会 副会长
专业杂志编委：
1、Viruses
2、Chinese Journal of Viral Diseases
3、Current HIV Research
4、PLOS ONE

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