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姓名: 齐琦
部门: 基础医学院
直属机构: 基础医学院
性别: 男
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个人简介
致力于肿瘤生物学和肿瘤药理学领域的研究。发表SCI收录论文61篇,其中包括国际知名在PNAS, Oncogene, JMC等在内的第一作者论文17篇(总影响因子达到81.838, 2017年公布)。研究成果获得国际同行的广泛关注和高度肯定。现已是包括Cancer Research, Biochemical Pharmacology, Molecular Pharmacology, Journal of Molecular Medicine 在内的20家SCI收率杂志的特邀审稿人。
学习经历
2006-2009,中国药科大学, 药理学博士学位
2003-2006,中国药科大学, 药理学硕士学位
1999-2003,郑州大学, 药学学士学位
工作经历
2018.6-至今,暨南大学医学院药理系 教授
2016.11-2018.5,埃默里大学医学院药理系化学生物学研发中心 Instructor (美国)
2015.3-2016.10,埃默里大学医学院药理系化学生物学研发中心Research Associate (美国)
2010.8-2015.2,埃默里大学医学院病理和实验医学系博士后(美国)
2009.8-2010.7,西弗吉尼亚大学医学院生理系伦道夫玛丽巴布癌症中心博士后(美国)
研究方向
主要论文
1.Qi Q, Obianyo O, Du Y, Fu H, Li S, Ye K. Blockade of asparagine endopeptidase inhibits cancer metastasis. J Med Chem. 2017 Sep 14;60(17):7244-7255.
2.Qi Q, Kang SS, Zhang S, Baker SJ, Fu H, Brat DJ, Ye K. Co-amplification of Phosphoinositide 3-kinase enhancer A and Cyclin-dependent kinas 4 Triggers Glioblastoma Progression. Oncogene. 2017 Aug 10;36(32):4562-4572.
3.Qi Q, Li DY, Luo HR, Guan KL, Ye K. Netrin-1 exerts oncogenic activities through enhancing Yes-associated protein stability. Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7255-60.
4.Qi Q, He K, Liu X, Pham C, Meyerkord C, Fu H. Ye K. Disrupting the PIKE-A/Akt interaction inhibits glioblastoma cell survival, migration, invasion, and colony formation. Oncogene. 2013 Feb 21;32(8):1030-40.
5.Qi Q, Liu X, Daniel Brat, Ye K. Merlin sumoylation is required for its tumor suppressor activity. Oncogene. 2014 Oct 9;33(41):4893-903.
6.He K, Qi Q, Chan CB, Xiao G, Liu X, Tucher-Burden C, Wang L, Mao H, Lu X, McDonald, F, Luo H, Fan Q, Weiss W, Sun S, Brat D, Wang L, Mao H, Fu H, Tao H, Ye K. Blockade of Glioma Proliferation Through Allosteric Inhibition of JAK2. Science signal. 2013 Jul 9;6(283):ra55. (Co-first author)
7.Qi Q, He K, Yoo MH, Chan CB, Liu X, Zhang Z, Olson JJ, Xiao G, Wang L, Mao H, Fu H, Tao H, Ye K. Acridine yellow G blocks glioblastoma growth via dual inhibition of epidermal growth factor receptor and protein kinase C kinases. J Biol Chem. 2012 Feb 24;287(9):6113-27.
8.Qi Q, Lu N, Li C, Zhao J, Liu W, You Q, Guo Q. Involvement of RECK in gambogic acid induced anti-invasive effect in A549 human lung carcinoma cells. Mol Carcinog. 2015 Jun;54 Suppl 1:E13-25.
9.Qi Q, Gu H, Yang Y, Lu N, Zhao J, Liu W, Ling H, You QD, Wang X, Guo Q. Involvement of matrix metalloproteinase 2 and 9 in gambogic acid induced suppression of MDA-MB-435 human breast carcinoma cell lung metastasis. J Mol Med. 2008 Dec;86(12):1367-77.
10.Qi Q, Lu N, Wang XT, Gu HY, Yang Y, Liu W, Li C, You QD, Guo QL. Anti-invasive effect of gambogic acid in MDA-MB-231 human breast carcinoma cells. Biochem Cell Biol. 2008 Oct;86(5):386-95.
11.Qi Q, You Q, Gu H, Zhao L, Liu W, Lu N, Guo Q. Studies on the toxicity of gambogic acid in rats. J Ethnopharmacol. 2008 May 22;117(3):433-8.
12.Li C, Lu N, Qi Q, Li F, Ling Y, Chen Y, Qin Y, Li Z, Zhang H, You Q, Guo Q. Gambogic acid inhibits tumor cell adhesion by suppressing integrin β1 and membrane lipid rafts-associated integrin signaling pathway. Biochem Pharmacol. 2011 Dec 15;82(12):1873-83. (Co-first author)