个人简介

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蓝平，博士，副研究员，硕士生导师。现任暨南大学先进与应用化学合成研究院副院长。主要研究方向为有机合成化学：包括天然产物全合成（在先进与应用化学合成研究院开展）以及新型食品添加剂的研发与制备（在理工学院食品科学与工程系开展）。目前主持科研项目包括国家自然科学基金青年项目1项，教育部海外名师项目1项，中央高校科研培育与创新基金1项，广州市企业横向项目2项。截止2019年2月，共发表SCI收录论文47篇，英文专著2篇，其中第一作者/通讯作者论文24篇，主要发表在Organic Letters, Journal of Organic Chemistry, Journal of Natural Products（天然产物全合成研究成果）和Journal of Agricultural and Food Chemistry（食品添加剂研究成果）等专业TOP期刊上。

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学习经历

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2011.10-2015.01 澳大利亚国立大学化学研究院哲学（有机化学）博士
导师：Martin G. Banwell教授（澳大利亚科学院院士）
研究方向为天然产物全合成

2008.09-2011.06 暨南大学药学院医学硕士（药物化学专业）
导师：陈卫民教授
研究方向为天然产物的结构修饰

2004.09-2008.06 中南民族大学生命科学学院理学学士（药学专业）

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工作经历

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2018.11至今 暨南大学先进与应用化学合成研究院副院长
2016.12至今 暨南大学理工学院食品科学与工程系副高（绿色通道）
2015.10-2016.12 澳大利亚沃尔特伊丽莎医学研究所（The Walter and Eliza Hall
Institute of Medical Research）博士后研究员
合作导师：Peter M. Colman教授（澳大利亚科学院院士）
Guillaume Lessene副教授及Peter Czabotar副教授

研究方向为化学生物学
2015.02-2015.10澳大利亚国立大学化学研究院博士后研究员
合作导师：Lewis N. Mander教授（澳大利亚科学院院士）
研究方向为天然产物全合成

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研究方向

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主要研究方向为有机合成化学，包括：
1.天然产物全合成，即运用有机合成相关技术以来源广泛的简单有机物为原料，制备具有生物活性的天然产物；
2.新型食品添加剂的研发与制备，主要致力于运用绿色合成技术，开发安全、高效的新型食品添加剂（乳化剂）；

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主要论文

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49.
Lan, P.; Banwell, M. G.*; Willis, A. C. Application of electrocyclic ring-opening and desymmetrizing nucleophilic trappings ofmeso-6,6-dibromobicyclo[3.1.0]hexanes to total syntheses of crinine and haemanthamine alkaloids.J. Org. Chem.2019,84, 3431–3466.
影响因子（4.849）引用次数（0）A1二区

48.
Zhang, Z.; Liu, Y.; Chen, Y.*; Li, L.;Lan, P.; He, D.; Song, J.*; Zhang, Y.* Transdermal delivery of 5-aminolevulinic acid by nanoethosome gels for photodynamic therapy of hypertrophic scars. ACS Appl. Mater. Inter.2019,11, 3704–3714.
影响因子（8.097）引用次数（0）A1一区

47.
Mikusek, J.; Nugent, J.;Lan, P.; Banwell, M. G.* A chemical synthesis study establishes the true structure of the potent anti-inflammatory agent myrsinoic acid F.J. Nat. Prod.2019,82, 96–100.
影响因子（3.885）引用次数（0）A1二区

46.
Benoit, B.; Tang, F.;Lan, P., Willis, A. C.; Banwell, M. G.* Synthetic studies on the marine-derived sesquiterpene (+)-viridianol: divergent behaviour of two structurally related, ring-fused cyclopropanes under the same hydrogenolytic conditions.Aust. J. Chem.Published online, https://doi.org/10.1071/CH18532
影响因子（1.558）引用次数（0）A2四区

45.
Lan, P.; Banwell, M. G.* Diastereoselective alkylation, allylation and benzylation reactions (of derived amides).Encyclopedia of Reagents for Organic Synthesis (e-EROS)2019, In press
著作章节

44.
Tang, F.;Lan, P.; Benoit, B.; Banwell, M. G.*; Willis, A. C.Total synthesis of (+)-viridianol, a marine-derived sesquiterpene embodying thedecahydrocyclobuta[d]indeneframework.J. Org. Chem.2018, 83, 14049–14056.
影响因子（4.849）引用次数（3）A1二区

43.
Yao, N.; Wang, C.; Hu, N.; Li, Y.; Liu, M.; Lei, Y.; Chen, M.; Chen, L.; Chen, C.;Lan, P.; Chen, W. M.; Chen, Z.; Ye, W. C.*; Zhang, D. M.* Inhibition of PINK1/Parkin-dependent mitophagy sensitizes multidrug-resistant cancer cells to the betulinic acid analogue B5G1.Cancer Lett.In press
影响因子（6.491）引用次数（0）A1二区

42.
Liang, M. Y.; Banwell, M. G.; Wang, Y.*;Lan, P.*Effect of variations in the fatty acid residue of lactose monoesters on their emulsifying properties and biological activities. J. Agric. Food Chem.2018,66, 12594–12603.
影响因子（3.412）引用次数（1）A1一区

41.
Qiu, Y.; Dlugosch, M.; Liu, X.; Khan, F.; Ward, J. S.;Lan, P.; Banwell, M. G.* The reductive cyclisation ofo-nitroarylated-α,β-unsaturated aldehydes and ketones with TiCl₃/HCl or Fe/HCl leading to 1,2,3,9-tetrahydro-4H-carbazol-4-ones and related heterocycles.J. Org. Chem.2018,83, 12023–12033.
影响因子（4.849）引用次数（0）A1二区

40.
Moujalled, D.; Pomilio, G.; Ghiurau, C.; Segal, D.; The, T. C.; Salmon, J.; Rijal, S.;Lan, P.; Kraus-Berthier, L.; Roberts, A.; Huang, D.; Maragno, A. L.; Lessene, G.; Geneste, O.; Wei, A.* A chemotherapy-free approach co-targeting pro-survival BCL-2 and MCL1 is highly efficacious in acute myeloid leukemia.Leukemiapublished online https://doi.org/10.1038/s41375-018-0261-3
影响因子（13.164）引用次数（2）A1一区

39.
Ma, Y. R.; Banwell, M. G.; Yan, R.*;Lan, P.*Comparative study of the emulsifying properties of a homologous series of long-chain 6?-O-acylmaltose esters.J. Agric. Food Chem.2018,66, 8832–8840.
影响因子（3.412）引用次数（1）A1一区

38.
Lan, P.; Banwell, M. G.*; Willis, A. C. Total synthesis of (±)-crinane from 6,6-dibromobicyclo[3.1.0]hexane and using a 5-exo-trigradical cyclisation reaction to assemble the requisite C3a-arylated perhydroindole.J. Org. Chem.2018,83, 8493–8498.
影响因子（4.849）引用次数（2）A1二区

37.
Bon, D. J.-Y. D.; Mander, L. N.*;Lan, P.*Syntheses of gibberellins A₁₅and A₂₄, the key metabolites in gibberellin biosynthesis.J. Org. Chem.2018,83,6566–6572.
影响因子（4.849）引用次数（0）A1二区

36.
Xiang, L.; Chen, J.; Yang, Y.; Xie, D.; Li, Y.; Liu, F.; Ma, H.; Wu, F.; Chen, K.;* Wu, H.;Lan, P.; Yuan, G.; Li, S.; Wang, Y.; Liu, J.; Zhu, J. Enhanced high permittivity and lowed dielectric loss in cellulose-fibre framework polymer microcomposites.Polym. Composite.2018, Article DOI: 10.1002/pc.24892
影响因子（2.324）引用次数（0）A2三区

35.
Liang, M. Y.; Chen, Y.; Banwell, M. G.; Wang, Y.*;Lan, P.*Enzymatic preparation of a homologous series of long-chain 6-O-acylglucose esters and their evaluation as emulsifiers.J. Agric. Food Chem.2018, 66, 3949–3956.
影响因子（3.412）引用次数（1）A1一区

34.
Chen, Y.;Lan, P.*TotalSyntheses and biological evaluation of theGanoderma lucidumalkaloids lucidimines B and C. ACS Omega2018,3,3471–3481.
影响因子（）引用次数（0）新期刊，暂无分区

33.
Lan, P.*; Herlt, A. J.; Willis, A. C.; Taylor, W. C.; Mander, L. N.*Structures of New Alkaloids fromrain forest treesGalbulimima belgraveanaandGalbulimima baccatain Papua New Guinea, Indonesia and Northern Australia.ACS Omega2018,3, 1912–1921.
影响因子（）引用次数（1）新期刊，暂无分区

32.
Taher, E. S.; Banwell, M. G.*; Buckler, J. N.; Yan, Q.;Lan, P.The exploitation of enzymatically-derivedcis-1,2-dihydrocatechols and relatedcompounds in the synthesis of biologically active natural products.Chem. Rec.2018,18, 239–264.
影响因子（3.855）引用次数（7）A1二区

31.
Jian, J.; Fan, J.; Yang, H.;Lan, P.; Li, M.; Liu, P.; Gao, H.*; Sun, P. H.*Totalsynthesisoftheflavonoidnatural product Houttuynoid Afromhouttuynia cordata.J. Nat. Prod.2018,81, 371–377.
影响因子（3.798）引用次数（2）A1二区

30.
Zhao, Q.; Zou, Y.; Huang, C.;Lan, P.; Zheng, J.; Ou, S.* Formation of a hydroxymethylfurfural-cysteine adduct and its absorption and cytotoxicity in Caco-2 cells.J. Agric. Food Chem.2017,65, 9902–9908.
影响因子（3.412）引用次数（4）A1一区

29.
Brouwer, J. M.;Lan, P.; Cowan, A. D.; Bernardini, J. P.; Birkinshaw, R. W.; van Delft, M. F.; Sleebs, B. E.; Robin, A. Y.; Wardad, A.; Tan, I. K.; Reljic, B.; Lee, E. F.; Fairlie, W. D.; Call, M. J.; Smith, B. J.; Dewson, G.; Lessene, G.; Colman, P. M.; Czabotar, P. E.* Conversion of Bim-BH3 from activator to inhibitor of Bak through structure-based design.Mol. Cell2017,68, 659–672.
影响因子（14.713）引用次数（6）A1一区

28.
Banwell, M. G.; Bolte, B.; Buckler, J. N.; Chang, E. L.;Lan, P.; Taher, E. S.; White, L. V.; Willis, A. C. Chemoenzymatic pathways for the synthesis of biologically active natural products.Journal and Proceedings of the Royal Society of New South Wales2016,149, 34–50.
影响因子（1.124）引用次数（9）A2四区

27.
Chang, E. L.; Benoit, B.;Lan, P.; Willis, A. C.; Banwell, M. G.*Chemoenzymatic total syntheses of the enantiomers of the protoilludanes 8-deoxydihydrotsugicoline and radudiol. J. Org. Chem.2016,81, 2078–2086.
影响因子（4.849）引用次数（12）A1二区

26.
Lan, P.; White, L. E.;Taher, E. S.;Guest, P. E.; Banwell, M. G.*; Willis, A. C. Chemoenzymatic synthesis of (+)-asperpentyn and the enantiomer of the structure assigned to aspergillusol A.J. Nat. Prod.2015,78, 1963–1968.
影响因子（3.798）引用次数（12）A1二区

25.
Lan, P.; Banwell, M. G.*; Willis, A. C.Chemoenzymatic synthesis of the enantiomer of 4,12-dihydroxysterpurene, the structure assigned to a metabolite isolated from the culture broth ofStereum purpureum.Org. Lett.2015,17, 166–169.
影响因子（6.579）引用次数（12）A1一区

24.
Crisp, A. L.; Li, J.;Lan, P.; Nugent, J.; Matousova, E.; Banwell, M. G.* The Palladium-catalysed intramolecular Alder-ene (IMAE) reactions of certain heteroatom-linked 1,6-enynes: the formation of hexahydro-indoles and –benzofurans.Aust. J. Chem.2015,68, 1183–1189.
影响因子（1.558）引用次数（8）A2四区

23.
White, L. V.;Lan, P.; Schwartz, B. D.; Willis, A. C.; Banwell, M. G.* New, homochiral synthons obtained through simple manipulations of enzymatically-derived 3-halo-cis-1,2-dihydrocatechols.Aust. J. Chem.2015,68, 1467–1471.
影响因子（1.558）引用次数（5）A2四区

22.
Banwell, M. G.*; Buckler, J.; Jackson, C. J.;Lan, P.; Ma, X.; Matousova, E.; Nugent, J. Devising new syntheses of the alkaloid galanthamine, a potent and clinically deployed inhibitor of acetylcholine esterase.Strategies and Tactics in Organic Synthesis2015,11, 29–50.
著作章节，引用次数（3）

21.
Yao, N.; Li, Y. J.; Zhang, D. M.; Liu, D. L.; Tang, M. K.; Yiu, A.; Li, Y.; Chen, W. M.; Lan, P.; Yao, Z.; Chen, Z. S.; Ye, W. C.* B4G2 induces mitochondrial apoptosis by the ROS-mediated opening of Ca²⁺-dependent permeability transition pores.Cell. Physiol. Biochem.2015,37, 838–852.
影响因子（2.875）引用次数（9）A1二区

20.
Lan, P.;Jackson,C. J.;Banwell, M. G.*; Willis, A. C.Synthesis of a D-ring isomer of galanthamineviaa radical-based Smiles rearrangement reaction.J. Org. Chem.2014,79, 6759–6764.
影响因子（4.849）引用次数（15）A1二区

19.
Lan, P.; Banwell, M. G.*; Willis, A. C.Chemoenzymatic total syntheses of ribisins A, B and D, polyoxygenated benzofuran derivatives displaying NGF-potentiating properties.J. Org. Chem.2014,79, 2829–2842.
?被选为重点推荐论文
影响因子（4.849）引用次数（26）A1二区

18.
Lan, P.; Banwell, M. G.*; Ward, J. S.; Willis, A. C.Chemoenzymatic total synthesis and reassignment of the absolute configuration of ribisin C.Org. Lett.2014,16, 228–231.
影响因子（6.579）引用次数（9）A1一区

17.
Zhang, D. M.; Li, Y. J.; Shu, C.; Ruan, Z. X.; Chen, W. M.; Yiu, A.; Peng, Y. H; Wang, J.;Lan, P.; Yao, Z.; Fung, K. P.; Fu, L. W.; Chen, Z. S.*; Ye, W. C.* Bipiperidinyl derivatives of 23-hydroxybetulinic acid reverse resistance of HepG2/ADM and MCF-7/ADR cells. Anti-Cancer Drugs2013,24, 441–454.
影响因子（1.784）引用次数（8）A2三区

16.
Lan,P.;Wu, Z. W.; Chen, W. N.; Sun, P. H.; Chen, W. M.* Molecular modeling studies on phosphonic acid-containing thiazole derivatives: design for fructose-1,6-bisphosphatase inhibitors.J. Mol. Model.2012,18, 973–990.
影响因子（1.736）引用次数（3）A2四区

15.
Zhang, D. M.; Shu, C.; Chen, J. J.; Sodani, K.; Wang, J.; Bhatnagar, J.;Lan, P.; Ruan, Z. X.; Xiao, Z. J.; Ambudkar, S. V.; Chen, W. M.; Chen, Z. S.*; Ye, W. C.* BBA, a derivative of 23-hydroxybetulinic acid, potently reverses ABCB1-mediated drug resistancein vitroandin vivo.Mol. Pharmaceut.2012,9, 3147–3159.
影响因子（4.384）引用次数（39）A1二区

14.
Lan, P.;Wang, J.; Zhang, D. M.; Shu, C.; Cao, H. H.; Sun, P. H.; Wu, X. M.; Ye, W. C.*; Chen, W. M.* Synthesis andantiproliferative evaluationof 23-hydroxybetulinic acid derivatives.Eur. J. Med. Chem.2011,46, 2490–2502.
影响因子（4.816）引用次数（24）A1二区

13.
Lan,P.;Chen, W. N.; Chen, W. M.* Molecular modeling studies on imidazo[4,5-b]pyridine derivatives as Aurora A kinase inhibitors using 3D-QSAR and docking approaches.Eur. J. Med. Chem.2011,46, 77–94.
影响因子（4.816）引用次数（38）A1二区

12.
Lan,P.;Chen, W. N.; Huang, Z. J.; Sun, P. H.; Chen, W. M.*Understanding the structure-activity
relationship of betulinic acid derivatives as anti-HIV-1 agents by using 3D-QSAR and docking.
J. Mol. Model.2011,17, 1643–1659.
影响因子（1.736）引用次数（17）A2四区

11.
Lan,P.;Sun, J. R.; Chen, W. N.; Sun, P. H.; Chen, W. M.* Molecular modeling studies ond-annulated benzazepinones as VEGF-R2 kinase inhibitors using docking and 3D-QSAR.J. Enzym. Inhib. Med. Chem.2011,26, 367–377.
影响因子（3.638）引用次数（8）A1二区

10.
Lan,P.;Chen, W. N.; Sun, P. H.; Chen, W. M.* 3D-QSAR and molecular docking studies of azaindole derivatives as Aurora B kinase inhibitors.J. Mol. Model.2011,17, 1191–1205.
影响因子（1.736）引用次数（11）A2四区

9.
Lan,P.;Chen, W. N.; Sun, P. H.; Chen, W. M.* 3D-QSAR studies on betulinic acid and betulin derivatives as anti-HIV-1 agents using CoMFA and CoMSIA.Med. Chem. Res.2011,20,1247–1259.
影响因子（1.402）引用次数（4）A2四区


8.
Sun, J. R.;Lan, P.; Sun, P. H.; Chen, W. M.* 3D-QSARand docking studies on pyrrolopyrimidine derivatives as LIM-Kinase 2 inhibitors.Lett. Drug Des. Discov.2011,8, 229–240.
影响因子（1.170）引用次数（8）A2四区

7.
Huang, Z. J.; Zeng, Y.;Lan, P.; Sun, P. H.; Chen, W. M.* Advances in structural modifications and biological activities of berberine: an active compound in traditional Chinese medicine.Mini-Rev. Med. Chem.2011,11, 1122–1129.
影响因子（2.645）引用次数（41）A2三区

6.
Song, Q. L.; Guo, B. Q.; Zhang, W.;Lan,P.;Sun, P. H.; Chen, W. M.* Design, synthesis and antibacterial activity of novel ketolides bearing an aryltetrazolyl-substituted alkyl side chain.J. Antibiot.2011,64, 571–581.
影响因子（2.150）引用次数（6）A2三区

5.
Wu, X.;Lan, P.; Liu, Z.; Ruan, Z. X.; Wang, H.; Wang, G. C.; Ye, W. C.; Li, Y. L. 3D-QSAR studies of natural steroidal saponins as anticancer agents in human nasopharyngeal carcinoma epithelial cells.Lett. Drug Des. Discov.2013,10,245–252.
影响因子（1.170）引用次数（1）A2四区

4.
Lan,P.;Xie, M. Q.; Yao, Y. M.; Chen, W. N.; Chen, W. M.* 3D-QSAR studies and molecular docking on [5-(4-Amino-1H-benzoimidazol-2-yl)-furan-2-yl]-phosphonic acid derivatives as fructose-1, 6-biphophatase inhibitors.J. Comput. Aided Mol. Des.2010,24, 993–1008.
影响因子（2.990）引用次数（11）A2三区

3.
Lan,P.;Chen, W. N.; Xiao, G. K.; Sun, P. H.; Chen, W. M.* 3D-QSAR and docking studies on pyrazolo[4,3-h]quinazoline-3-carboxamides as cyclin-dependent kinase 2 (CDK2) inhibitors.Bioorg. Med. Chem. Lett.
2010,20, 6764–6772.
影响因子（2.420）引用次数（36）A2三区

2.
Lan,P.;Huang, Z. J.; Sun, J. R.; Chen, W. M.* 3D-QSAR and molecular docking studies on fused pyrazoles as p38α mitogen-activated protein kinase inhibitors.Int. J. Mol. Sci.2010,11, 3357–3374.
影响因子（2.862）引用次数（27）A2三区

1.
Hu, L.;Lan, P.;Song, Q. L.; Huang, Z. J.; Sun, P. H.; Zhuo, C.; Wang, Y.; Xiao, S.; Chen, W. M.* Synthesis and antibacterial activity of C-12 pyrazolinyl spiro ketolides.Eur. J. Med. Chem.2010,45, 5943–5949.
影响因子（3.447）引用次数（12）A1二区

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承担课题

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1.基于稠环偕二卤代环丙烷不对称开环反应的天然产物全合成研究，国家自然科学基金（青年项目），2019-2021，25万，主持，编号：**
2.Fissitungfine A的全合成与抗增殖活性研究，科研培育与创新基金，2017-2020，15万，主持，编号：**
3.“功能性食品配料绿色合成研究”（澳大利亚国立大学Martin G. Banwell院士合作），教育部海外名师项目，2018-2023，100万，主持，编号：2018-HWMS001
4.高纯度蔗糖脂肪酸单酯绿色制备研究，横向课题，广州嘉德乐生化科技有限公司，2018-2021，10万，主持
5.糖尿病相关基因精准分型项目，横向课题，广州普麦健康咨询有限公司，2019-2022，50万，主持
6.山苍子精油绿色萃取及综合利用技术开发与产业化示范，广东省“扬帆计划”引进创新创业团队，2017-2022，300万，参与

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发明专利

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1. 叶文才，陈卫民，蓝平，张冬梅，王娇，舒畅，曹惠惠，于淼。23-羟基白桦酸衍生物及其制备方法和用途。中国发明专利(公开号CNA)

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讲授课程

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1.《Food Additives》本科生全英授课
2.《有机合成》本科生

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