个人概括

姓名： 黄俊 性别：男 职称：教授 导师资格：博导
单位：病原生物学与免疫学教研室
学历：博士 毕业院校：中山大学
电子邮件： hj165@sina.com 通信地址： 广州市番禺区新造镇广州医科大学
招生专业： 免疫学


所获荣誉

1. 广州市科技新星


社会兼职
1. 广东省免疫学会副理事长
2. 广东省寄生虫学会理事
3. 广东省医学病毒学专业委员会理事
4. 《热带医学杂志》编辑


主持科研项目
1. 广州市科技计划项目，γδT细胞在疟原虫诱导小鼠病变过程中的作用及机制研究，20万, 在研
2. 广东省自然科学基金，TLR+B细胞在日本血吸虫肝肉芽肿形成中的作用及机制， 10万，在研
3. 国家自然科学基金面上项目，疟原虫感染在肺脏诱导的γδTCR+髓系细胞的研究， 56万，在研
4. 广东省教育厅重大项目，γδT细胞在日本血吸虫感染小鼠肝免疫微环境中的作用， 50万，在研，结题
5. 广东省医学科研基金，Ⅰ型登革病毒诱导的记忆性T细胞的特征， 0.5万，结题
6. 广州市高校科研计划项目，效应性/记忆性NKT细胞在日本血吸虫感染所致肝脏病变过程中的作用，8万，结题
7. 广州市科技局科技新星项目， Th9细胞对日本血吸虫虫卵肉芽肿及纤维化的影响，30万，结题
8. 国家自然科学基金青年项目， Th17细胞对日本血吸虫虫卵肉芽肿及肝纤维化的作用， 20万，结题
9. 广东省自然科学基金博士启动资金， Th17细胞对日本血吸虫虫卵肉芽肿及肝纤维化形成的影响， 3万，结题


部分代表性第一和通讯作者论文：
1. Haixia Wei^1,#, Chenxi Jin^1,#, Anping Peng^2,#, Hongyan Xie¹, Shihao Xie ¹, Yuanfa Feng¹, Anqi Xie¹, Jiajie Li¹, Chao Fang¹, Quan Yang¹, Huaina Qiu¹, Yanwei Qi¹, Zhinan Yin^3,4, Xinhua Wang^1,*, and Jun Huang^1,*. Characterization of γδT cells in lung of Plasmodium yoelii-infected C57BL/6 mice. Malar J, 2021 Feb 15;20(1):89.
2. Quan Yang ^1,2*#, Hongyan Xie ^1#, Xing Li ³, Yuanfa Feng ¹, Shihao Xie ¹, Jiale Qu ¹, Anqi Xie ¹, Yiqiang Zhu ¹, Lu Zhou ¹, Jinxue Yang ¹, Xiaohao Hu ¹, Haixia Wei¹, Huaina Qiu ¹, Wenjuan Qin ^4*, and Jun Huang ^1,2*. Interferon regulatory factor 4 regulates the development of polymorphonuclear myeloid-derived suppressor cells through the transcription of c-Myc in cancer. Frontiers in Immunology. 2021.1, 12,627072.
3. Kunhua Xu, ^?a Wenming Chen^,?b Xu Chen,^a Biao Wang,^a Jun Huang^*c and Xu Tian^*a. Organocatalytic Asymmetric Friedel-Crafts Alkylation/Hemiketalization/Lactonization Cascade Reactions: Highly Enantioselective Synthesis of Furo[2,3-b]benzofuranones. Org Chem Front, 2020.7, 1679–1684.
4. Hefei Cha^{1, #}, Hongyan Xie^{1, #}, Chenxi Jin^{1, #}, Yuanfa Feng^1,#, Shihao Xie¹, Anqi Xie¹, Quan Yang¹, Yanwei Qi¹, Huaina Qiu¹, Qiongli wu², Zhinan Yin³, Jianbing Mu^{4, *}, Jun Huang^1,*. Adjustments of γδ T cells in the lung of Schistosoma japonicum-infected C56BL/6 mice. Frontiers in Immunology. 2020.6, 11:1045.
5. Jiale Qu^{1, ?}, Xiuxue Yu^{1, ?}, Chenxi Jin^{1, ?}, Yuanfa Feng¹, Shihao Xie¹, Hongyan Xie¹, Quan Yang¹, Yanwei Qi¹, Huaina Qiu¹, Hongyuan Chen², Yi Zhou^3, * and Jun Huang^1, *. TLR7 Modulated T Cell Response in the Mesenteric Lymph Node of Schistosoma japonicum-Infected C57BL/6 Mice. Journal of Immunology Research. 2019.12，2019: **.
6. Yi Zhao^{1, ?}, Quan Yang^{1, ?}, Chenxi Jin^{1, ?}, Yuanfa Feng¹, ShihaoXie¹, Hongyan Xie¹, Yanwei Qi¹, Huaina Qiu¹, Hongyuan Chen², Ailin Tao¹, Jianbing Mu³, Wenjuan Qin⁴ and Jun Huang^1, *. Changes of CD4+ and CD8⁺ CD103⁺ pulmonary T cells in S. japonicum infected C57BL/6 mice. BMC Infectious Diseases. 2019.11, 19: 999 (IF=2.688).
7. Quan Yang ^#, Jiale Qu ^#, Chenxi Jin, Yuanfa Feng, Shihao Xie, Jinxin Zhu, Gaoshen Liu, Hongyan Xie, Huaina Qiu ,Yanwei Qi, Jiangbing Mu*, Jun Huang*. Schistosoma japonicum infection promotes the accumulation of Tfh cells through down-regulation of caspase-3–mediating apoptosis. Frontiers in Immunology. 2019, 10: 2154 (IF=5.085).
8. Dianhui Chen¹, Yi Zhao², Yuanfa Feng², Chenxi Jin², Quan Yang², Huaina Qiu², Hongyan Xie², Sihao Xie², Yi Zhou³，Jun Huang². Expression of TLR2, TLR3, TLR4 and TLR7 on pulmonary lymphocytes of Schistosoma japonicum infected C57BL/6 mouse. Innate Immunity. 2019 .4; 25(5): 224–234.
9. Zitao Li ^1,a, , Anping Peng ^2,a, Yuanfa Feng ^3,a, Xiaona Zhang ⁴, Fenghua Liu ¹, Chuangqi Chen ¹, Xin Ye ³, Jiale Qu ³, Chenxi Jin³, Mei Wang³, Huaina Qiu ³, Yanwei Qi ³, Jun Huang ^3,5,b, Quan Yang^3,5,b. Detection of T lymphocyte subsets and related functional molecules in follicular fluid of patients with polycystic ovary syndrome. Scientific Reports. 2019.9, 15: 6040.
10. Li J, Jin C, Wu C, Huang J*. PD-1 modulating Mycobacterium tuberculosis-specific polarized effector memory T cells response in tuberculosis pleurisy. J Leukoc Biol. 2019; 106: 733-747.
11. Jiale Qu^#, Lu Li^#, Hongyan Xie^#, Xiaona Zhang, Quan Yang, Huaina Qiu, Yuanfa Feng, Chenxi Jin, Nuo Dong* and Jun Huang*. TLR3 modulates the response of NK cells against Schistosoma japonicum. J Immunol Res. 2018 .8; **.
^12. Quan Yang ^?, Huaina Qiu ^?, Hongyan Xie ^?, Yanwei Qi, Hefei Cha,Jiale Qu, Mei Wang, Yuanfa Feng, Xin Ye, Jianbing Mu^*, Jun Huang^*. A Schistosoma japonicum infection promotes the expansion of myeloid-derived suppressor cells by activating the JAK/STAT3 pathway. J Immunol. 2017.7; 198(12): 4716-4727.
^13. Lu Li^#, Hongyan Xie^#, Mei Wang^#, Jiale Qu, Hefei Cha, Quan Yang, Yuanfa Feng, Yanwei Qi, Huaina Qiu, Nuo Don* and Jun Huang *. Characteristics of IL-9 induced by Schistosoma japonicum infection in C57BL/6 mouse liver. Scientific Reports. 2017.5; 7(1):2343.
^14. Hefei Cha^#,Wenjuan Qin^#, Quan Yang^#, Hongyan Xie, Jiale Qu, Mei Wang, Daixiong Chen, Fang Wang, Nuo Dong, Longhua Chen* and Jun Huan*. Differential pulmonic NK and NKT cell responses in Schistosoma japonicum-infected mice. Parasitol Res. 2017.2, 116(2): 559-567.
15. Chen D^#, Xie H^#, Cha H, Qu J, Wang M, Li L, Yu S, Wu C, Tang X, Huang J. Characteristics of Schistosoma japonicum infection induced IFN-γ and IL-4 co-expressing Plasticity Th cells. Immunology. 2016.9, 149(1):25-34.
16. He Wang, Shu Yang, Hong Zhou, Mingna Sun, Lingran Du, Minyan Wei, Meixia Luo, Jingzhu Huang, Hongzhu Deng, Yinghong Feng, Jun Huang* and Yi Zhou*. Aloperine executes antitumor effects against multiple myeloma through dual apoptotic mechanisms. Journal of Hematology & Oncology. 2015.3, 8:26.
17. Hongyan Xie^#, Dianhui Chen^#, Lu Li, Xiuxue Yu，Changyou Wu, Haigang Gu, Xiaoping Tang, Anping Peng, Jun Huang*. Immune response of γδT cells in Schistosome japonicum infected C57BL/6 mouse liver. Parasite Immunology，2014.12, 36 (12): 658–667.
18. Xueping Luo^#, Hongyan Xie^#, Dianhui Chen, Xiuxue Yu, Fan Wu, Lu Li, Jun Huang*. Changes in NK and NKT cells in mesenteric lymph nodes after a Schistosoma japonicum infection. Parasitol Res, 2014.3, 113(3):1001-1009.
19. Dianhui Chen^#, Hongyan Xie^#, Xueping Luo, Xiuxue Yu, Xiaoying Fu , Haigang Gu, Changyou Wu, Xiaoping Tang, Jun Huang*. Roles of Th17 cells in pulmonary granulomas induced by Schistosoma japonicum in C57BL/6 mice. 2013.10, Cellular Immunology. 285 (1-2): 149-157.
20. Dianhui Chen^#, Xueping Luo^#, Hongyan Xie, Zhiyan Gao, Huilong Fang and Jun Huang*. Characteristics of IL-17 induction by Schistosoma japonicum infection in C57BL/6 mouse liver. Immunology, 2013.8, 139(4)：523-532.
21. Hongyan Xie^#, Dianhui Chen, Xueping Luo^#, Zhiyan Gao, Huilong, Fang, Jun Huang*. Some characteristics of IL-5-producing T cells in mouse liver induced by Schistosoma japonicum infection. Parasitol Res, 2013.5, 112(5): 1945-1951.
22. Jun Huang, Yingnan Cao, Xianzhang Bu, Changyou Wu*. Residue analysis of a CTL epitope of SARS-CoV spike protein by IFN-γ production and bioinformatics prediction. BMC immunology, 2012, 13:50.
23. Jun Huang, Yinnan cao, Jiali Du, Changyou Wu*. Priming with SARS-CoV S DNA and boosting with SARS-CoV S peptides specific for CD4⁺ and CD8⁺ T cells promote cellular immune responses. Vaccine. 2007, 28;25(39-40): 6981-91.
24. Jun Huang, Rui Ma, Chang-you Wu*. Immunization with SARS-CoV S DNA vaccine generates memory CD4⁺ and CD8⁺ T cell immune responses. Vaccine, 2006, 24(23): 4905–4913.