袁中文，男，副主任中药师，博士。
毕业院校：澳门科技大学（中药质量研究国家重点实验室）
工作单位：附属第三医院
【联系邮箱】zhwyuan1985@163.com
【研究方向】代谢性疾病药理；临床化学分析

【主要科研项目】

(1) 国家自然科学基金青年项目，**，基于Galectin-3调控胰岛素抵抗的青钱柳黄酮治疗非酒精性脂肪肝炎物质基础研究，21万元，2019/01-2021/12，主持，在研
(2) 广东省自然科学基金博士启动项目，2018A，基于肝细胞线粒体膜稳定性调节的青钱柳黄酮治疗非酒精性脂肪肝炎物质基础研究，10万元，2018/05-2021/5，主持，在研
【所获荣誉和奖励】

广州医科大学附属第三医院 “毅文人才工程”扬帆计划培养对象
【主要论文及著作（代表性）】

(1) Yuan ZhongWen^#, Li YaZhuo^#, Liu ZhongQiu, Feng SenLing, Zhou Hua, Liu ChangXiao, Liu Liang*, Xie Ying*. Role of tangeretin as a potential bioavailability enhancer for silybin: Pharmacokinetic and pharmacological studies[J]. Pharmacological Research, 2018, 128:153-166.
(2) Zhong-Wen Yuan, Elaine Lai-Han Leung, Xing-Xing Fan, Hua Zhou,Wen-Zhe Ma, Liang Liu*, Ying Xie*. Quantitative evaluation of berberine subcellular distribution and cellular accumulation in non-small cell lung cancer cells by UPLC–MS/MS[J]. Talanta, 2015, 144:20-8.
(3) Chang Qu^#, Zhong-Wen Yuan^#, Xiu-Ting Yu^#, Yan-Feng Huang, Guang-Hua Yang, Jian-Nan Chen, Xiao-Ping Lai, Zi-Ren Su, Hui-Fang Zeng^*, Ying Xie^*, Xiao-Jun Zhang^*. Patchouli alcohol ameliorates dextran sodium sulfate-induced experimental colitis and suppresses tryptophan catabolism[J]. Pharmacological Research, 2017, 121:70-82.
(4) Xiao-Jun Zhang^# , Zhong-Wen Yuan^#, Chang Qu , Xiu-Ting Yu, Tao Huang, Ping Vicky Chen, Zi-Ren Su, Yao-Xing Dou , Jia-Zhen Wu, Hui-Fang Zeng^*, Ying Xie*, Jian-Nan Chen*. Palmatine ameliorated murine colitis by suppressing tryptophan metabolism and regulating gut microbiota[J]. Pharmacological Research, 2018, 137: 34-46.
(5) Bi Xiaoli^#, Yuan Zhongwen^#, Qu Biao, Zhou Hua, Liu Zhongqiu, Xie Ying*, Piperine enhances the bioavailability of silybin via inhibition of efflux transporters BCRP and MRP2[J]. Phytomedicine, 2019, 54: 98-108.
(6) Rinkiko Suguro^#, Xiao-cong Pang^#, Zhong-wen Yuan^#, Si-yao Chen, Yi-ZhunZhu, YingXie*. Combinational applicaton of silybin and tangeretin attenuates the progression of non-alcoholic steatohepatitis (NASH) in mice via modulating lipid metabolism[J]. Pharmacological Research, 2020, 151:104519.
(7) 袁中文*, 陈苏静, 林泽敏, 陈连娣, 梅峥嵘, 王颖. 青钱柳总黄酮的提取工艺优化及体内外活性研究[J]. 医药导报, 2020, 39(04): 441-447.
(8) 袁中文*, 许婳婳, 钟柳婷, 王颖, 刘少志, 李振华. 青钱柳黄酮干预肥胖大鼠胰岛素抵抗的作用研究[J]. 中药药理与临床, 2019, 35(03): 50-55.
(9) 张婧,冯森玲,汪明,刘琪莎,刘少志,袁中文*.基于网络药理学和分子对接技术探索透解祛瘟颗粒治疗新型冠状病毒肺炎的分子机制研究[J].中药药理与临床,2020,36(05):21-28.