广东药科大学研究生导师简介


个人照

姓 名 陈磊

性 别 男



出生年月
1981 年 04
月

籍贯 河南


民 族 汉
政治面貌
中共党员


最后学历 博士
最后学位
研究生


技术职称
副教授
行政职务 无




工作单位
片

中药学院

Email
chenlei0080@ 163.com




主要研究领域


主要从事中药质量控制与药效物质基础。


主要工作经历


2014. 07－至今 广东药科大学中药学院 副教授、硕士生导师


主要教育经历


1. 2006.09－2009.07 北京中医药大学 中药学专业博士生
2. 2003.09－2006.07 河南中医学院 药物分析学专业硕士生
3. 1999.09－2003.07 河南中医学院 中药制药专业本科生


代表性 5 个社会、学会及学术兼职

1. 中国民族医药学会药理学分会 常务理事


代表性 10 项科研项目

1. 国家自然科学研究基金面上项目，81673556，基于肠道微生态、胰岛素信号通路和代谢网络调控的苦参抗糖尿病物质基础及作用机制研究，主持
2. 国家自然科学研究基金青年项目，81303193，基于体内动态效应的中药苦参抑制血管新生组分间相互作用研究，主持
3. 广东省自然科学研究基金面上项目，2017A030313753，基于“药物-机体”双重代谢网络的苦参抗糖尿病药效物质基础及作用机制研究，主持


发表代表性 10 篇论文、专著或教材

论文：

(1) Lei Chen(#); Jing Shao; Yun Luo; Linlin Zhao; Kairui Zhao; Yanping Gao; Shumei Wang; Yi
Liu(*), An integrated metabolism in vivo analysis and network pharmacology in UC rats reveal
anti-ulcerative colitis effects from Sophora flavescens EtOAc extract, Journal of
Pharmaceutical and Biomedical Analysis, 2020. DOI:
10.1016/j.jpba.2020.113306
(2) Jing Shao(#); Yi Liu(#)(*); Huan Wang; Yun Luo; Chen Lei(*), An integrated fecal
microbiome and metabolomics in T2DM rats reveal anti-diabetes effects from
host-microbial metabolic axis of EtOAc extract from Sophora flavescens, Oxidative Medicine
and Cellular Longevity, 2020. Accepted.
(3) Lei Chen(#); Xiaobin Huang; Huan Wang; Jing Shao; Yun Luo; Kairui Zhao; Yi Liu(*); Shumei
Wang, Integrated metabolomics and network pharmacology strategy for ascertaining
the quality marker of flavonoids for Sophora flavescens, Journal of
Pharmaceutical and Biomedical Analysis, 2020. DOI: 10.1016/j.jpba.2020.113297
(4) Wang Huan(#); Liu Yi(#)(*); Shao Jing; Luo Yun; Cai Wei; Chen Lei(*), Rapid and accurate
simultaneous determination of seven short-chain fatty acids in feces by gas
chromatography – mass spectrometry (GC-MS): application in type 2 diabetic rats and drug therapy,
Analytical Letters, 2020. DOI: 10.1080/00032719.2020.1740928
(5) Huang Xiaobin(#); Yuan Luowei(#); Shao Jing; Yang Yan; Liu Yi; Lu Jinjian(*); Chen
Lei(*),Cytotoxic effects of flavonoids from root of Sophora flavescens in cancer cells,
Natural Product Research, 2020. DOI: 10.1080/14786419.2020.1712382


(6) Yun Luo(#); Hongpei Cui; Yi Liu(*); Lei Chen(*), Metabolomics and biomarkers in
ocular matrix: beyond ocular diseases, International Journal of Ophthalmology, 2020. DOI:
10.1080/14786419.2020.1712382
(7) Chen Lei(#)(*); Zhao Linlin(#); Cai Wei; Shao Jing; Huang Xiaobin; Liu Yi(*), An
accurate and reproducible method for simultaneous determination of four flavonoids in
EtOAc extracts from Sophora flavescens Ait. in rat plasma based on UHPLC Q-Exactive Mass
spectrometry: application to a pharmacokinetics study, Biomed Chromatogr, 2019, 33(3): e4447
(8) Liu Yi(#); Chen Lei; Cai Wei; Zhao Linlin; Mo Zhixian(*), Use of an UHPLC-MS/MS Method for
Determination of Kuraridin and Characterization of Its Metabolites in Rat Plasma after
Oral Administration, Molecules, 2018, 23(2),132
(9) Liu Lianghong(#); Zhang Jiayu(#); Zheng Binjie; Guan Ying; Wang Liting; Chen Lei(*); Cai
Wei(*), Rapid characterization of chlorogenic acids in Duhaldea nervosa based on
ultra-high-performance liquid chromatography-linear trap quadropole-Orbitrap-mass
spectrometry and mass spectral trees similarity filter technique, Journal of Separation
Science, 2018, 41(8): 1764~1774
(10) Huang Rong(#); Liu Yi; Zhao LinLin; Chen Xixin; Wang Feng; Cai Wei; Chen Lei(*), A new
avonoid from Sophora avescens Ait. , Natural Product Research, 2017, 31(19): 2228~2232