所属学院:
中研院 导师性质:
外单位的兼职导师 导师类别:
硕士生导师

姓名
王来友
性别
男
出生年月 1977.12



最高学位
博士
最后学历
博士毕业
政治面貌
农工党党员

工作单位
药学院
职务

导师职称
教授

今年是否招生
否
指导博士生人数
0
获博士学位人数
0

指导硕士生人数
15
获硕士学位人数
10
电子邮箱 wly1999@sina.com

指导学生学科(专业)领域
药理学;中药学;药学;

导师科研情况自述 △Education and Training:Mar.2009 -Jun.2010 School of Medicine, Kansas Medical Center, Postdoctoral Fellowship, USASep.2003 -Jul.2006 School of Pharmaceutical Sciences, Sun-yat Sen University; Doctor of Medicine, ChinaSep.2004 -Aug.2005 Joint lab of L’oreal with Faculty of Pharmacy and Medicine, Franche-Comte University, France Sep.2001 -Jul.2003 School of life Sciences, Sun-yat Sen university; Master of Biology, China Sep.1996 -Jul.2000 Faculty of pharmacy, Hubei University of Traditional Chinese Medicine; Bachelor of Medicine, China△Academic and Professional Appointments and Activities：Sep.2010 -present Associate Professor，Institute of Chinese Medical Sciences, Guangdong Pharmaceutical UniversityJul.2006 -Mar.2009 Lecturer，Department of pharmacology, Guangdong Pharmaceutical University, ChinaJul. 2000 -Sep.2001 Assistant Engineer，Department of GMP, JiangSu Heng-rui Pharmaceutical Company, Ltd. China△Main academic achievements：1.Published articles 发表论文Liang WL, Le X, Li HJ, Yang XL, Chen JX, Xu J, Liu HL, Wang LY, Wang KT, Hu KC, Yang DP, Lan WJ. Exploring the chemodiversity and biological activities of the secondary metabolites from the marine fungus Neosartorya pseudofischeri. Mar Drugs. 2014 Nov 24;12(11):5657-76.（IF=3.512）Lan WJ, Liu W, Liang WL, Xu Z, Le X, Xu J, Lam CK, Yang DP, Li HJ, Wang LY. Pseudaboydins A and B: novel isobenzofuranone derivatives from marine fungus Pseudallescheria boydii associated with starfish Acanthaster planci. Mar Drugs. 2014 Jul 14;12(7):4188-99.（IF=3.512）（通讯作者）Zhang S, Huang WB, Wu L, Wang LY, Ye LB, Feng BH. A novel suberoylanilide hydroxamic acid histone deacetylase inhibitor derivative, N25, exhibiting improved antitumor activity in both human U251 and H460 cells. Asian Pac J Cancer Prev. 2014;15(10):4331-8.（IF=1.5）Wang L, Tao W, Luo D, Hu Y, Bei W, Guo J. Potential synergistic effects of Chinese herbal prescription FTZ components detected in blood towards hepatic lipid-modulating targets. Complement Ther Med. 2014 Oct;22(5):887-93.（IF=2.216）（第一作者）Fan H, Chen YY, Bei WJ, Wang LY, Chen BT, Guo J. In Vitro Screening for Antihepatic Steatosis Active Components within Coptidis Rhizoma Alkaloids Extract Using Liver Cell Extraction with HPLC Analysis and a Free Fatty Acid-Induced Hepatic Steatosis HepG2 Cell Assay. Evid Based Complement Alternat Med. 2013;2013:459390.（IF=2.175）Li F, Lu J, Cheng J, Wang L, Matsubara T, Csanaky IL, Klaassen CD, Gonzalez FJ, Ma X. Human PXR modulates hepatotoxicity associated with rifampicin and isoniazid co-therapy. Nat Med. 2013 Apr;19(4):418-20.（IF=28.054）Wei Ye Tao, Lai You Wang, Guo Hua Cheng, Jun Liu, Lang Ping Tang. Mechanism of Sini Decoction on Coronary Heart Disease in Molecular Level. Advanced Materials Research. 2013,756-759:2868.Xie ZL, Li HJ, Wang LY, Liang WL, Liu W, Lan WJ. Trichodermaerin, a new diterpenoid lactone from the marine fungus Trichoderma erinaceum associated with the sea star Acanthaster planci. Nat Prod Commun. 2013 Jan;8(1):67-8.（IF=0.924）Cao Y, Bei W, Hu Y, Cao L, Huang L, Wang L, Luo D, Chen Y, Yao X, He W, Liu X, Guo J. Hypocholesterolemia of Rhizoma Coptidis alkaloids is related to the bile acid by up-regulated CYP7A1 in hyperlipidemic rats. Phytomedicine. 2012 Jun 15;19(8-9):686-92.（IF=2.877）Zhong X, Guo J, Wang L, Luo D, Bei W, Chen Y, Yan K, Peng J. Analysis of the Constituents in Rat Serum after Oral Administration of Fufang Zhenzhu Tiaozhi Capsule by UPLC-Q-TOF-MS/MS. Chromatographia. 2012 Feb;75(3-4):111-129.（IF=1.37）Li F, Lu J, Wang L, Ma X. CYP3A-mediated generation of aldehyde and hydrazine in atazanavir metabolism. Drug Metab Dispos. 2011 Mar;39(3):394-401.（IF=3.334）Wang L, Li F, Lu J, Li G, Li D, Zhong XB, Guo GL, Ma X. The Chinese herbal medicine Sophora flavescens activates pregnane X receptor. Drug Metab Dispos. 2010 Dec;38(12):2226-31.（IF=3.334）（第一作者）Li F, Wang L, Guo GL, Ma X. Metabolism-mediated drug interactions associated with ritonavir-boosted tipranavir in mice. Drug Metab Dispos. 2010 May;38(5):871-8.（IF=3.334）Su QB, He F, Wang XD, Guan S, Xie ZY, Wang LY, Lu YJ, Gu LQ, Huang ZS, Chen X, Huang M, Zhou SF. Biotransformation and pharmacokinetics of the novel anticancer drug, SYUIQ-5, in the rat. Invest New Drugs. 2008 Apr;26(2):119-37.（IF=2.927）2.The invention patent发明专利制备补骨脂素的合成方法，发明人：杨得坡，李楚源，王来友，陈矛，黄世亮，王德勤；申请号：1.7，申请日：2003.10.28.3.Science and technology projects undertaken承担的科技项目2013年广东省自然科学基金面上项目，基于FAT/CD36调控通路的调肝降脂方防治药物性脂肪肝机制研究2012年国家自然青年科学基金项目，孕烷X受体介导抗结核药联合应用所致肝损伤机制研究，项目批准号：**.4.Awarded achievement获奖成果2012年度广东省科学技术奖 项目名称：防治糖脂代谢紊乱性疾病方药物质基础及作用机理研究，项目编号：B16-0-1-01.