南方医科大学研究生导师简介-刘思德

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基本信息　姓名：刘思德（LIU SIDE）
　技术职称：主任医师、教授
　工作单位：南方医科大学南方医院消化科
　导师类型：学术型博导
　研究方向与专业：胃肠道肿瘤的早期诊断与治疗、新型胶囊内镜系统的研制与开发、人工肝新型生物细胞材料的研制/内科学（消化系病）
　联系方式：liuside@163.com
　学术任职：中华医学会消化内镜学分会委员兼副秘书长、中华医学会消化病学分会委员、广东省医学会消化病学分会主任委员、广东省肝脏病学会理事长、广东省抗癌协会肿瘤内镜学专委会候任主任委员、广东省医学会消化内镜学分会常委

从事的主要研究方向及其特点和意义、开展新医疗、新技术等情况、国内所处的学术地位　　长期从事结肠镜诊疗及早期大肠癌内镜诊治的临床与研究工作，多次在日本及欧洲研习消化内镜技术，结肠镜技术精湛，近5年来，主持国家及省部级重大科研项目10余项，总科研经费超过5000万元，发表论文190余篇，其中以第一或通讯作者在国际知名杂志发表SCI论文30余篇，单篇最高影响因子18.187，获国家发明专利授权8项，实用新型专利授权10项。

个人荣誉　　1、广东省科学技术奖一等奖：结直肠癌内镜诊治特征及相关分子机制的实验研究2、教育部首届中国高校科技成果交易会“特别金奖”：智能胶囊胃镜系统

学术专著　　1、图解消化内镜培训教材，高等教育出版社，20112、下消化道内镜检查技术，中华医学音像电子出版社，2012.3、早期胃癌，科学出版社，2017

代表性论文论文标题期刊名称影响因子
Risk factors for surgery in patients with retention of endoscopic capsuleScand J Gastroenterol2.526
Successful closure of esophagomediastinal fistula with endoclips and an endoloop after endoscopic submucosal dissectionEndoscopy6.629
Directed Differentiation of Adult Liver Derived Mesenchymal Like Stem Cells into Functional HepatocytesSci Rep4.259
Endoscopic mucosa-sparing lateral dissection for treatment of gastric submucosal tumors: a prospective cohort studyENDOSCOPY6.629
Association between patient characteristics and magnetically controlled capsule endoscopy findingsSaudi J Gastroenterol1.368
Establishment and characterization of an immortalized human hepatocyte line for the development of bioartificial liver systemCytotechnology1.461
Clonorchis sinensis infection detected by capsule endoscopyClinics and Research in Hepatology and Gastroenterology2.623
Withaferin A induces apoptosis by ROS-dependent mitochondrial dysfunction in human colorectal cancer cellsBiochem Biophys Res Commun2.559
Imbalanced LIMK1 and LIMK2 expression leads to human colorectal cancer progression and metastasis via promoting β-catenin nuclear translocationCell Death Dis5.638
Snail/FOXK1/Cyr61 Signaling Axis Regulates the Epithelial-Mesenchymal Transition and Metastasis in Colorectal CancerCell Physiol Biochem5.500
Retroflexion-assisted endoscopic mucosal resection: a useful and safe method for removal of low rectal laterally spreading tumorsSurg Endosc3.256
A novel quality scoring system for the evaluation of individual colonoscopy: A multicenter retrospective studyJ Gastroenterol Hepatol3.504
Comparison of the diagnostic efficacy of white light endoscopy and magnifying endoscopy with narrow band imaging for early gastric cancer: a meta-analysisGastric Cancer3.719
Effectiveness and safety of endoscopic resection for gastric GISTs: a systematic reviewMinim Invasive Ther Allied Technol1.418
A modified endoscopic method for resection of gastric submucosal tumorSurg Endosc3.747
Relationships of capsule endoscopy Lewis score with clinical disease activity indices, C-reactive protein, and small bowel transit time in pediatric and adult patients with small bowel Crohn's diseaseMedicine (Baltimore)1.803
Higher PKD3 expression in hepatocellular carcinoma (HCC) tissues predicts poorer prognosis for HCC patientsClin Res Hepatol Gastroenterol2.323
Overexpression of Srcin1 contributes to the growth and metastasis of colorectal cancerInt J Oncol3.079
Long-term outcomes of endoscopic submucosal dissection versus laparoscopic resection for gastric stromal tumors less than 2 cmJ Gastroenterol Hepatol3.452
Cyanoacrylate Injection Versus Band Ligation in the Endoscopic Management of Acute Gastric Variceal Bleeding: Meta-Analysis of Randomized, Controlled Studies Based on the PRISMA StatementMedicine (Baltimore)5.723
Decreased expression of PBLD correlates with poor prognosis and functions as a tumor suppressor in human hepatocellular carcinomaOncotarget6.359
RUFY3 interaction with FOXK1 promotes invasion and metastasis in colorectal cancerSci Rep4.259
MiR-646 inhibited cell proliferation and EMT-induced metastasis by targeting FOXK1 in gastric cancerBr J Cancer6.176
Rufy3 promotes metastasis through epithelial-mesenchymal transition in colorectal cancerCancer Lett6.375
Comparison of endoscopic submucosal tunneling dissection and thoracoscopic enucleation for the treatment of esophageal submucosal tumorsGastrointest Endosc6.501
Should the Integrity of Mucosa Be Considered in Endoscopic Resection of Gastric Submucosal Tumors?Gastroenterology16.716

在研课题课题名称课题级别经费（万元）
血管紧张素II及血管紧张素（1-7）对肝脏线粒体自噬及NLRP3炎症小体的调控作用：NASH的新机制国家级67
新型可扩展性生物人工肝支持系统的合作开发与临床前研究省级50
广东省消化系统疾病临床医学研究中心省级100
应用于上消化道早癌筛查的家用便携式智能胶囊胃镜系统的研制省级800
肠道微生态失衡临床诊断标准的建立和完善国家级550
MiR-500a-5p在结直肠癌中的功能及其分子网络调控机制的研究国家级55

招生信息导师类型：?学术型博导
分委员会：?第一临床医学学位评定分委员会
培养单位：?南方医院
招生专业：?医学>临床医学>内科学（消化系病）
在读研究生人数：?硕士（10）博士（12）在职博士（2）
申招研究生名额：?硕士（3）博士（3）在职博士（2）
研究生论文盲审通过率：?硕士（100%）博士（100%）
培养研究生论文获奖情况：?无

培养研究生其他获奖情况：?2014年全国“挑战杯”创业计划竞赛金奖