王耿，博士 Geng Wang, Ph.D.
教授，博士生导师Professor
细胞生物学(Cell Biology)
E-mail：wangengfuan@163.com



1994-1998年，厦门大学化学系，学士学位；
1998-2000年，厦门大学化学系；
2000-2006年，爱荷华大学生物化学系，博士；
2006-2012年，加州大学洛杉矶分校化学与生物化学系，博士后；
2012-2019年，清华大学生命科学学院，特别研究员，博士生导师；
2019-，厦门大学生命科学学院，教授，博士生导师。
1994-1998 B.S., Department of Chemistry, Xiamen University
1998-2000 Department of Chemistry, Xiamen University
2000-2006 Ph.D., Department of Biochemistry, University of Iowa
2006-2012 Postdoctoral fellow, Department of Chemistry and
Biochemistry, University of California, Los Angeles
2012-2019 Principle Investigator, Tsinghua University School of LifeSciences
2019- Professor, Xiamen University School of Life Sciences


研究领域（Research Area）
线粒体RNA的运输、代谢、和功能，及其和其他重要细胞过程之间的关联和调控
线粒体疾病的医疗研究
哺乳动物正常衰老机制的研究
Mitochondrial RNA import, metabolism, functions, and the regulation network between them and other important cellular processes
Therapeutic research on mitochondrial diseases
Mechanistic study of normal ageing in mammals



代表性论文（Selected Publications）(*为通讯作者）
1.Zheng Q, Liu P, Gao G, Yuan J, Wang P, Huang J, Xie L, Lu X, Di F, Tong T, Chen J, Lu Z, Guan J, Wang G*. (2019) Mitochondrion-processed TERC regulates senescence without affecting telomerase activities. Protein Cell, doi: 10.1007/s13238-019-0612-5. [Epub ahead of print].
2.Huang J, Liu P, Wang G*. (2018) Regulation of mitochondrion-associated cytosolic ribosomes by mammalian mitochondrial ribonuclease T2 (RNASET2). J biol chem, 293, 19633-19644.
3.Cheng Y, Liu P, Zheng Q, Gao G, Yuan J, Wang P, Huang J, Xie L, Lu X, Tong T, Chen J, Lu Z, Guan J, Wang G*. (2018) Mitochondrial Trafficking and Processing of Telomerase RNA TERC.Cell Reports, 24(10):2589-2595.
4.Liu P, Huang J, Zheng Q, Xie L, Lu X, Jin J, Wang G* (2017) Mammalian mitochondrial RNAs are degraded in the mitochondrial intermembrane space by RNASET2. Protein & Cell8(1): 735-749.
5.Wang G, Shimada E, Nili M, Koehler CM, Teitell MA (2015) Mitochondria-targeted RNA import. Methods Mol Biol. 1264:107-116.
6.Wang G, Shimada E, Koehler CM, Teitell MA (2012) PNPASE and RNA trafficking into mitochondria. Biochimi Biophys Acta. 1819(9-10):998-1007.
7.Wang G, Shimada E, Zhang J, Hong JS, Smith GM, Teitell MA, Koehler CM (2012) Correcting human mitochondrial mutations with targeted RNA import. Proc Natl Acad Sci U S A. 109(13):4840-4845.
8.von Ameln S, Wang G, Boulouiz R, Rutherford MA, Smith GM, Li Y, Pogoda HM, Nürnberg G, Stiller B, Volk AE, Borck G, Hong JS, Goodyear RJ, Abidi O, Nürnberg P, Hofmann K, Richardson GP, Hammerschmidt M, Moser T, Wollnik B, Koehler CM, Teitell MA, Barakat A, Kubisch C (2012) A mutation in PNPT1, encoding mitochondrial-RNA-import protein PNPase, causes hereditary hearing loss. Am J Hum Genet. 91(5):919-927.
9.Wang G, Chen HW, Oktay Y, Zhang J, Allen EL, Smith GM, Fan KC, Hong JS, French SW, McCaffery JM, Lightowlers RN, Morse HC 3rd, Koehler CM, Teitell MA (2010) PNPASE regulates RNA import into mitochondria. Cell. 142(3):456-467.
10.Wang G, Deschenes RJ (2006) Plasma membrane localization of Ras requires class C Vps proteins and functional mitochondria in Saccharomyces cerevisiae. Mol Cell Biol, 26:3243-3255.






荣誉、奖励及参加学术团体的情况（Honors and award, Professional service）


主持1项科技部国家重点研发计划、1项国家自然科学基金重大研究计划培育项目。