黄力行，1986年11月生，博士，副教授，硕士生导师。曾获得福建省****科学基金（2019年），福建省高校****科研人才培育计划（2018年），首批集美大学青年拔尖人才支持计划（2018）等人才工程资助。先后主持国家自然科学基金青年基金、福建省****科学基金和福建省自然科学基金等科研项目。目前主要从事水产病原微生物致病分子机理方面的研究工作，在变形假单胞菌和溶藻弧菌致病机制领域取得一定进展。以第一作者或通讯作者在“Emerg Microbes & Infec”，“Front Immunol”，“Front Microbiol”，“Front Cell Infect Microbiol”，“Sci Rep”，“J Hazard Mater”，“Fish & Shellfish Immun”等期刊发表SCI论文20余篇。目前为“Fish & Shellfish Immun”，“Aquaculture”，“MicrobiologyOpen”，“Environ Sci Technol”，“Toxicol Sci”，“Aquat Toxicol”，“Chemosphere”，“IEEE Transactions on Biomedical Engineering”等期刊审稿人；任中国水产学会青年工作委员会委员，Frontiers in Cellular and Infection Microbiology客座副主编。
一、学习和工作经历：
厦门大学学士（2005-2009）；
厦门大学博士（2009-2014）；
集美大学水产学院讲师（2014-2017）
集美大学水产学院副教授（2017至今）
二、主持和承担的科研项目：
主持“leuO通过ncRNA调节生物被膜信号通路在溶藻弧菌毒力调控中的作用与机制”（福建省****科学基金）
主持“新型非编码RNA Vvrr1参与溶藻弧菌毒力调控的机制研究”（国家自然科学基金青年科学基金项目）
主持“温度敏感Pyoverdine合成酶编码基因L321_07973调控变形假单胞菌致病性的分子机制初步研究”（福建省自然科学基金计划项目）
主持“铁载体合成酶编码基因L321_00207对变形假单胞菌致病性的影响”（福建省中青年教师教育科研项目）
主持“大黄鱼内脏白点病口服疫苗研发”（大黄鱼企业国家重点实验室开放课题）
主持“Pyoverdine合成酶编码基因L321_01406调控变形假单胞菌致病性的初步研究”（李尚大学科建设基金）
主持“利用RNAi技术研究Flagellar assembly pathway在溶藻弧菌粘附过程中的作用”（农业部东海海水健康养殖重点实验室开放性课题）
主持“溶藻弧菌转录组测序所显示的三个新基因的功能初步鉴定”（国家海洋局海洋生物遗传资源重点实验室开放性课题）
参与“LuxR家族调控蛋白对嗜水气单胞菌在鳗鲡巨噬细胞内存活的调控及机制研究”（国家自然科学基金青年科学基金项目）
参与“全反式维甲酸调控miR-34a-E2F1/3-Eag1信号通路抑制骨肉瘤恶性表型的研究”（国家自然科学基金青年科学基金项目）
参与“海洋渔用疫苗工程技术研究中心”（海洋经济区域创新发展示范项目）
参与“海水鱼益生菌及海水净化微生物制剂开发与产业化”（厦门市海洋经济发展专项资金项目）
参与“几种高附加值海洋天然产物规模化生产关键技术研究与示范”（海洋公益性行业科研专项经费项目）
参与“用斑马鱼模型研究多环芳烃的心血管发育毒性及其机制”（国家自然科学基金）。
参与“利用斑马鱼研究多环芳烃的视觉发育毒性和机制”（国家自然科学基金）。
参与“海洋药源生物种质资源库建设课题子课题”（国家海洋局）
参与“‘重大项目为牵引，导师团队为保障’研究生创新能力培养研究”（福建省本科高校教育教学改革研究项目）
三、部分代表性科研成果：
Zuo Y F, Zhao L M, Xu X J, Zhang J N, Zhang J L, Yan Q P, Huang L X. Mechanisms underlying the virulence regulation of new Vibrio alginolyticus ncRNA Vvrr1 with a comparative proteomic analysis. Emerg Microbes Infect, 2019, 8(1): 1604-1618. (IF: 6.21)
Huang L X, Zhao L M, Liu W J, Xu X J, Su Y Q, Qin Y X, Yan Q P. Dual RNA-Seq unveils Pseudomonas plecoglossicida htpG gene functions during host-pathogen interactions with Epinephelus coioides. Front Immunol, 2019, 10: 984. (IF: 4.72)
Huang L X, Liu W J, Jiang Q L, Zuo Y F, Su Y Q, Zhao L M, Qin Y X, Yan Q P. Integration of transcriptomic and proteomic approaches reveals the temperature-dependent virulence of Pseudomonas plecoglossicida. Front Cell Infect Microbiol, 2018, 8: 207. (IF: 3.52)
Zhang Y Y, Huang L X, Zhao Y J, Hu T H. Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF-β signaling pathway. Chemosphere, 2017, 168:1506-1514. (Co-first authors). (IF: 4.21)
Huang L X, Xi Z H, Wang C G, Zhang Y Y, Yang Z B, Zhang S Q, Chen Y X, Zuo Z H. Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation. Scientific Reports, 2016, 6. (IF: 5.23)
Luo G, Huang L X, Su Y Q, Qin Y X, Xu X J, Zhao L M, Yan Q P. flrA, flrB and flrC regulate adhesion by controlling the expression of critical virulence genes in Vibrio alginolyticus. Emerg Microbes Infect. 2016, 5(8): e85. (Co-first authors). (IF: 5.61)
Huang L X, Hu J, Su Y Q, Qin Y X, Kong W D, Zhao L M, Ma Y, Xu X J, Lin M, Zheng J, Yan Q P. Genome-wide detection of predicted non-coding RNAs related to the adhesion process in Vibrio alginolyticus using high-throughput sequencing. Frontiers in Microbiology, 2016, 7: 619. (IF: 4.17)
Huang L X, Huang L, Yan Q P, Qin Y X, Ma Y, Lin M, Xu X J, Zheng J. The TCA pathway is an important player in the regulatory network governing Vibrio alginolyticus adhesion under adversity. Frontiers in Microbiology, 2016, 7: 40. (IF: 4.17)
Huang L X, Hu J, Su Y Q, Qin Y X, Kong W D, Ma Y, Xu X J, Lin M, Yan Q P. Identification and characterization of three Vibrio alginolyticus non-coding RNAs involved in adhesion, chemotaxis, and motility processes. Frontiers in Cellular & Infection Microbiology, 2015, 5: 56. (IF: 5.22)
Wang L, Huang L X, Su Y Q, Qin Y X, Kong W D, Ma Y, Xu X J, Lin M, Zheng J, Yan Q P. Involvement of the flagellar assembly pathway in Vibrio alginolyticus adhesion under environmental stresses. Frontiers in Cellular & Infection Microbiology, 2015, 5: 59. (Co-first authors). (IF: 5.22)
Huang L X, Gao D X, Zhang Y Y, Wang C G, Zuo Z H^*. Exposure to low dose benzo[a]pyrene during early life stages causes symptoms similar to cardiac hypertrophy in adult zebrafish. J Hazard Mater. 2014, 276: 377-82. (IF: 4.84)
Huang L X, Wang C G, Zhang Y Y, Wu M F, Zuo Z H^*. Phenanthrene causes ocular developmental toxicity in zebrafish embryos and the possible mechanisms involved. J Hazard Mater. 2013, 261: 172-80. (IF: 4.84)

四、联系方式：
Email：lixinghuang@outlook.com
通讯地址：福建省厦门市集美区印斗路43号，集美大学水产学院。邮编：361021。



Lixing Huang, Ph.D.
Associate Professor of Microbiology
Fisheries College, Jimei University, Xiamen, Fujian 361021, PR China
Email：lixinghuang@outlook.com
Research Topics
Pathogenic mechanisms of bacteria, host-pathogen interactions, regulation of gene expression.
Education
B.S., Xiamen University, 2009
Ph.D., Xiamen University, 2014
Representative Publications
Zuo Y F, Zhao L M, Xu X J, Zhang J N, Zhang J L, Yan Q P, Huang L X. Mechanisms underlying the virulence regulation of new Vibrio alginolyticus ncRNA Vvrr1 with a comparative proteomic analysis. Emerg Microbes Infect, 2019, 8(1): 1604-1618. (IF: 6.21)
Huang L X, Zhao L M, Liu W J, Xu X J, Su Y Q, Qin Y X, Yan Q P. Dual RNA-Seq unveils Pseudomonas plecoglossicida htpG gene functions during host-pathogen interactions with Epinephelus coioides. Front Immunol, 2019, 10: 984. (IF: 4.72)
Huang L X, Liu W J, Jiang Q L, Zuo Y F, Su Y Q, Zhao L M, Qin Y X, Yan Q P. Integration of transcriptomic and proteomic approaches reveals the temperature-dependent virulence of Pseudomonas plecoglossicida. Front Cell Infect Microbiol, 2018, 8: 207. (IF: 3.52)
Zhang Y Y, Huang L X, Zhao Y J, Hu T H. Musk xylene induces malignant transformation of human liver cell line L02 via repressing the TGF-β signaling pathway. Chemosphere, 2017, 168:1506-1514. (Co-first authors). (IF: 4.21)
Huang L X, Xi Z H, Wang C G, Zhang Y Y, Yang Z B, Zhang S Q, Chen Y X, Zuo Z H. Phenanthrene exposure induces cardiac hypertrophy via reducing miR-133a expression by DNA methylation. Scientific Reports, 2016, 6. (IF: 5.23)
Luo G, Huang L X, Su Y Q, Qin Y X, Xu X J, Zhao L M, Yan Q P. flrA, flrB and flrC regulate adhesion by controlling the expression of critical virulence genes in Vibrio alginolyticus. Emerg Microbes Infect. 2016, 5(8): e85. (Co-first authors). (IF: 5.61)
Huang L X, Hu J, Su Y Q, Qin Y X, Kong W D, Zhao L M, Ma Y, Xu X J, Lin M, Zheng J, Yan Q P. Genome-wide detection of predicted non-coding RNAs related to the adhesion process in Vibrio alginolyticus using high-throughput sequencing. Frontiers in Microbiology, 2016, 7: 619. (IF: 4.17)
Huang L X, Huang L, Yan Q P, Qin Y X, Ma Y, Lin M, Xu X J, Zheng J. The TCA pathway is an important player in the regulatory network governing Vibrio alginolyticus adhesion under adversity. Frontiers in Microbiology, 2016, 7: 40. (IF: 4.17)
Huang L X, Hu J, Su Y Q, Qin Y X, Kong W D, Ma Y, Xu X J, Lin M, Yan Q P. Identification and characterization of three Vibrio alginolyticus non-coding RNAs involved in adhesion, chemotaxis, and motility processes. Frontiers in Cellular & Infection Microbiology, 2015, 5: 56. (IF: 5.22)
Wang L, Huang L X, Su Y Q, Qin Y X, Kong W D, Ma Y, Xu X J, Lin M, Zheng J, Yan Q P. Involvement of the flagellar assembly pathway in Vibrio alginolyticus adhesion under environmental stresses. Frontiers in Cellular & Infection Microbiology, 2015, 5: 59. (Co-first authors). (IF: 5.22)
Huang L X, Gao D X, Zhang Y Y, Wang C G, Zuo Z H^*. Exposure to low dose benzo[a]pyrene during early life stages causes symptoms similar to cardiac hypertrophy in adult zebrafish. J Hazard Mater. 2014, 276: 377-82. (IF: 4.84)
Huang L X, Wang C G, Zhang Y Y, Wu M F, Zuo Z H^*. Phenanthrene causes ocular developmental toxicity in zebrafish embryos and the possible mechanisms involved. J Hazard Mater. 2013, 261: 172-80. (IF: 4.84)