姓 名： 李娟
性 别： 女
职 称： 教授
学 历： 博士
职 务：
电 话：
专 业： 分析化学
电子邮件： lijuan@fzu.edu.cn
研究方向： 新型光学成像探针、活细胞膜分析，纳米诊疗



教育工作经历
2008/9 - 2013/7 福州大学，分析化学，博士（导师：杨黄浩教授）
2013/9 - 2014/10 美国佛罗里达大学，博士后 （导师：谭蔚泓教授）
2014/11-至今 福州大学化学学院
教学简介
承担本科生课程：
《生物化学》
《仪器分析实验》
《综合实验》
承担研究生课程：
《高等分析实验》


科研简介


社会兼职





科研项目
1、资助类别：国家优秀青年科学基金
项目时间：2017年01月至 2019年12月
项目名称：生化分析和生物成像
2、资助类别：国家自然科学基金青年项目
项目时间：2016年01月至 2018年12月
项目名称：智能响应MRI/NIR荧光双模态纳米探针的构建及其在活体肿瘤成像分析中的应用
3、资助类别：福建省自然科学基金****科学基金项目，
2017 年04 月至2020 年04 月，
项目名称：软 X 射线发光纳米探针的构建及其生物医学应用
4、资助类别：福建省自然科学基金
项目时间：2016年04月至 2019年04月
项目名称：智能响应纳米探针在活细胞肿瘤成像分析中的应用
5、福建省高校****科研人才培育计划
福建省教育厅
2016年



代表性论文
(1)Jingying Li, Jie Zhou, Tong Liu, Shan Chen, Juan Li* and Huanghao Yang*, Circular DNA: a stable probe for highly efficient mRNA imaging and gene therapy in living cells, Chem. Commun., 2018, 54, 896-899.
(2)Hong Liang, Ying Wu, Xiang-Yu Ou, Jing-Ying Li and Juan Li*, Au@Pt nanoparticles as catalase mimics to attenuate tumor hypoxia and enhance immune cell-mediated cytotoxicity, Nanotechnology, 2017, 28, 465702
(3)Cheng-Yi Hong, Shu-Xian Wu, Shi-Hua Li, Hong Liang, Shan Chen, Juan Li,* Huang-Hao Yang,*, and Weihong Tan*, Semipermeable Functional DNA-Encapsulated Nanocapsules as Protective Bioreactors for Biosensing in Living Cells, Anal. Chem., 2017, 89, 5389-5394.
(4)Liang Song, Xia-Hui Lin, Xiao-Rong Song, Shan Chen, Xiao-Feng Chen, Juan Li* and Huang-Hao Yang*, Repeatable deep-tissue activation of persistent luminescent nanoparticles by soft X-ray for high sensitivity long-term in vivo bioimaging, Nanoscale, 2017, 9, 2718-2722.
(5)Xiao-Rong Song, Shi-Hua Li, Jiayong Dai, Liang Song, Guoming Huang, Ruhui Lin, Juan Li,* Gang Liu, and Huang-Hao Yang*, Polyphenol-Inspired Facile Construction of Smart Assemblies for ATP- and pH-Responsive Tumor MR/Optical Imaging and Photothermal Therapy, Small, 2017, DOI: 10.1002/smll..
(6)Juan Li, ^* Liuting Mo, Chun-Hua Lu, Ting Fu, Huang-Hao Yang* and Weihong Tan*, Functional nucleic acid-based hydrogels for bioanalytical and biomedical applications, Chem. Soc. Rev., 2016, 45, 1410-1431.
(7)Juan Li,Shuxian Wu, Cuichen Wu, Liping Qiu, Guizhi Zhu, Cheng Cui, Yuan Liu, Weijia Hou, Yanyue Wang, Liqin Zhang, I-ting Teng, Huang-Hao Yang* and Weihong Tan*, Versatile surface engineering of porous nanomaterials with bioinspired polyphenol coatings for targeted and controlled drug delivery, Nanoscale, 2016, 8, 8600-8606.
(8)Youxiu Lin, Qian Zhou, Juan Li,^* Jian Shu, Zhenli Qiu, Yuping Lin, and Dianping Tang^*, Magnetic Graphene Nanosheet-Based Microfluidic Device for Homogeneous Real-Time Electronic Monitoring of Pyrophosphatase Activity Using Enzymatic Hydrolysate-Induced Release of Copper Ion, Anal. Chem. 2016, 88, 1030-1038.
(9)Juan Li, Cheng-Yi Hong, Shu-Xian Wu, Hong Liang, Li-Ping Wang, Guoming Huang, Xian Chen, Huang-Hao Yang,^* Dihua Shangguan,^* and Weihong Tan^* , Facile Phase Transfer and Surface Biofunctionalization of Hydrophobic Nanoparticles Using Janus DNA Tetrahedron Nanostructures, J. Am. Chem. Soc. 2015, 137, 11210-11213.
(10)Juan Li, Cheng Zheng, Sena Cansiz, Cuichen Wu, Jiehua Xu, Cheng Cui, Yuan Liu, Weijia Hou, Yanyue Wang, Liqin Zhang, I-ting Teng, Huang-Hao Yang^*, Weihong Tan^*, Self-assembly of DNA Nanohydrogels with Controllable Size and Stimuli-Responsive Property for Targeted Gene Regulation Therapy, J. Am. Chem. Soc., 2015, 137, 1412-1415.
(11)Kaimei Ke, Lisen Lin, Hong Liang, Xian Chen, Chao Han, Juan Li*, Huang-Hao Yang, Polypyrrole nanoprobes with low non-specific protein adsorption for intracellular mRNA detection and photothermal therapy, Chem. Commun., 2015, 51, 6800 - 6803.

获奖情况



其他