姓名：张龙斌
性别：男


职称：助理研究员
学历：理学博士

电话：**
电子邮箱：longbin_z@163.com

研究方向：蛋白质与酶工程、基因调控、组学研究

教育工作经历：
2020.01至今福州大学生物科学与工程学院助理研究员
2016.07-2020.01 华侨大学医学院讲师
2011.09-2016.07 浙江大学微生物学博士
2007.09-2011.07 福建师范大学生物技术学士

承担课程：
1、本科生：生物化学；有机化学；
2、研究生：

科研简介：
1、微生物发酵产酶（漆酶、褐藻胶裂解酶等）及其工业化运用的研究；
2、微生物功能性代谢物（寡聚糖、羟基喹啉醌等）的生产与应用；
3、微生物组学的生物信息分析（转录组、代谢组、蛋白组、宏基因组等；
4、昆虫病源真菌的基因功能及调控机理研究；

社会兼职：
转化医学杂志青年编委

科研项目：
1、国家自然科学基金青年基金：MicroRNA对大脑皮层神经发生的反馈环路调控机制。（2018-2020年，20万，主持）
2、福建省自然科学基金青年基金：MicroRNA-26对大脑皮层神经发生的反馈环路调控机制。（2018-2021年，4万，主持）
3、福州大学人才项目：基于转录组与代谢组分析Sur7调控球孢白僵菌生长的分子机理。（2020-2022年，10万，主持）

代表性论文：(#共同第一作者；*为通讯作者)
1.Zhang LB, Feng MG*. Antioxidant enzymes and their contributions to biological control potential of fungal insect pathogens. Appl. Microbiol. Biotechnol. 2018. 102: 4995-5004. (Review)
2.Zhang LB, Tang L, Ying SH, Feng MG*. Two eisosome proteins play opposite roles in autophagic control and sustain cell integrity, function and pathogenicity in Beauveria bassiana. Environ Microbiol. 2017. 19:2037-2052.
3.Zhang LB^#, Mubarak T^#, Chen Y^#, Lee T, Pollock A, Sun T*. Counter-balance between Gli3 and miR-7 is required for proper morphogenesis and size control of the mouse brain. Front. Cellular Neurosci. 2018. 12:259.
4.Zhang LB, Tang L, Ying SH, Feng MG*. Distinct roles of cytoplasmic thioredoxin reductases (Trr1/Trr2) in the redox system involving cysteine synthesis and host infection of Beauveria bassiana. Appl. Microbiol. Biotechnol. 2016. 100: 10363-10374.
5.Zhang LB, Tang L, Ying SH, Feng MG*. Regulative roles of glutathione reductase and four glutaredoxins in glutathione redox, antioxidant activity, and iron homeostasis of Beauveria bassiana. Appl. Microbiol. Biotechnol. 2016. 100: 5907-5917.
6.Zhang LB, Tang L, Ying SH, Feng MG*. Subcellular localization of six thioredoxins and their antioxidant activity and contributions to biological control potential in Beauveria bassiana. Fungal Genet. Biol. 2014. 76, 1–9.
7.Zhang HJ^#, Zhang LB^#, Sun T*. Cohesive regulation of neural progenitor development by microRNA miR-26, its host gene Ctdsp and target gene Emx2 in the mouse embryonic cerebral cortex. Front. Mol. Neurosci. 2018. 11: 44.
8.Du KZ, Zhang LB, Sun T*. m6A RNA methylation controls neural development and is involved in human diseases. Mol. Neurobiol. 2018. DOI: 10.1007/s12035-018-1138-1.
9.Hussain G, Zhang LB, Rasul A, Anwar H, Sohail MU, Razzaq A, Aziz N, Shabbir A, Ali M, Sun T*. Role of plant-derived flavonoids and their mechanism in attenuation of Alzheimer’s and Parkinson’s Diseases: An update of recent data. Molecules. 2018. Doi: 10.3390/molecules**.
10.Floris G, Zhang LB, Follesa P, Sun T*. Regulatory role of circular RNAs and neurological disorders, Mol Neurobiol. 2017. 5: 5156-5165.
11.Wang ZL, Zhang LB, Feng MG*. Catalases play differentiated roles in the adaptation of a fungal entomopathogen to environmental stresses. Environ. Microbiol. 2013. 15, 409-418.
12.Zhang HJ., Chang YF, Zhang LB, Kim SN, Otaegi G, Zhang Z, Nie YZ, Mubarak T, Li C, Qin CF, Xu ZH, Sun T*. Upregulation of microRNA miR-9 is associated with microcephaly and Zika virus infection in mice. Mol Neurobiol. 2018. DOI: 10.1007/s12035-018-1358-4.