姓名：郭隆华
性别：男
职称：副教授
学历：博士
职务：硕导
电话：**
专业：分析化学
电子邮件：guolh@fzu.edu.cn
研究方向：纳米光学生物传感;分子发光;现代分离分析
教育工作经历
2009.7-2011.8在新加坡南洋理工大学从事博士后研究工作;
2009.7毕业于福州大学分析化学专业，获博士学位；
教学简介
1、《分析化学B》
2、《仪器分析A》
3、《分析化学B实验》
4、《无机与分析化学C实验》
科研简介
i）局域表面等离子共振（LSPR）；
ii）表面增强拉曼光谱（SERS）；
iii）表面增强电化学发光（SEECL）；
iv）纳米光学分离分析。
近5年在相关领域国际权威期刊如J.Am.Chem.Soc.,Small,Anal.Chem.,Lab.Chip.,Chem.Commun.,J.Mater.Chem.,Biosens.Bioelectron.等发表研究论文50余篇，其中大部分论文发表在影响因子大于5.0的国际著名期刊上；论文已被SCI期刊引用逾300次,H-index=12。
申请中国发明专利13项。
社会兼职
科研项目
国家自然科学基金：基于表面增强电化学发光的重金属、兽药残留分析及其迁移规律研究（21277025，2013/1-2016/12)。
国家自然科学基金：基于非对称修饰贵金属纳米粒子LSPR耦合的食品安全传感器的研制与应用（21205017，2013/1-2015/12)。
教育部留学回国人员科研启动基金：局域表面等离子共振增强电致化学发光机理及应用研究（第46批：2013-2016）
福建省高校杰青项目：基于“热点”效应的表面增强拉曼光谱（SERS）活性基底的制备及其在环境与食品安全分析中的应用研究（JA13024，2014.1-2016.12）
福建省自然科学基金：局域表面等离子共振增强电致化学发光基础及应用研究（2012J01036，2012.1-2014.12）。
福建省教育厅A类科技项目：基于纳米粒子二聚体的食品安全传感器研制与应用（JA12039，2012.8－2015.8）
国家人才培养基金“能力提高”项目：基于人唾液基因筛查的地沟油鉴定新方法研究（J2012－027，2012－2014）
福州大学科研启动基金：局域表面等离子共振纳米生物传感平台的构建及其在食品安全分析中的应用研究（0460-022448，2012.03-2015.03）。
福州大学科技发展基金：局域表面等离子共振增强电化学发光及其在环境与食品安全分析中的应用（2012-XQ-8，2012.6-2014.8）。
参与项目：
国家自然科学基金：基于工具酶技术的电化学生物传感界面的构建及应用（21275031，2013/1-2016/12)。
国家基金：基于离子液体/超分子体系的热控电致化学发光分子识别传感器研究（20905034，2010/1-2012/12）。
国家自然科学基金：可寻址电化学细胞传感器的构建及其应用研究（20905013，2010/1-2012/12）。
国家自然科学基金：近海海域中赤潮毒素的仿生分子识别生物传感器研究（41076059，2010/1-2010/12）。
国家自然科学基金：基于质谱的流感病毒翻译后修饰的蛋白质组学研究(20928005,2010/1-2011/12)
国家自然科学基金：基于加压毛细管电色谱—质谱联用技术的赤潮毒素的高通量快速检测（20877019，2009/1-2011/12）；
国家自然科学基金：基于可印刷离子液体/纳米功能材料的新型电致化学发光传感器研究（20775014，2008/1-2010/12）。
代表性论文
2013：
LonghuaGuo,YangXu,AbdulRahimFerhan,GuonanChen,andDong-HwanKim.Orientedgoldnanoparticleaggregationforcolorimetricsensorswithsurprisinglyhighanalyticalfiguresofmerit.JournalofAmericanChemicalSociety,2013,135(33),12338-12345.
YangXu,LonghuaGuo,*LianzhuHuang,KannanPalanisamy,DonghwanKimandGuonanChen.Facilepreparationofpartiallyfunctionalizedgoldnanoparticlesviaasurfactant-assistedsolid-phaseapproach.JournalofColloid&InterfaceScience,2013,409,32–37.
RongHuang,DaifangWang,ShuzhenLiu,LonghuaGuo*,FangfangWang,ZhenyuLin,BinQiu,GuonanChen.Preparativeseparationofenantiomersbasedonfunctionalnucleicacidsmodifiedgoldnanoparticles.Chariality,ASAP.DOI:10.1002/chir.22208.
LonghuaGuo,AbdulRahimFerhan,HailanChen,ChangmingLi,GuonanChen,SeungpyoHong,Dong-HwanKim.Distance-mediatedplasmonicdimersforreusablecolorimetricswitches:ameasurablepeakshiftofover60nm.Small,2013,9,2,234–240.SelectedasaFrontispiece.
LonghuaGuo,*DaifangWang,YangXu,BinQiu,ZhenyuLin,HongDai,Huang-HaoYangandGuonanChen.*DiscriminationofenantiomersbasedonLSPRbiosensorsfabricatedwithweakenantioselectiveandnonselectivereceptors.BiosensorsandBioelectronics,2013,47，199-205.
RongHuang,WenmingXiong,DaifangWang,LonghuaGuo*,ZhenyuLin,LishuangYu,KedanChu,BinQiu,GuonanChen.*Label-freeaptamer-basedpartialfillingtechniqueforenantioseparationanddeterminationofdl-tryptophanwithmicellarelectrokineticchromatography.Electrophoresis.2013,34(2),254-259.
SuyanQiu,MiaoMiao,TianxiWang,ZhenyuLin,LonghuaGuo,BinQiu,GuonanChen.Afluorescentprobefordetectionofhistidineincellularhomogenateandovalbuminbasedonthestrategyofclickchemistry.BiosensBioelectron.2013,42,332-336.
SuyanQiu,XianghuiLi,WenmingXiong,LidanXie,LonghuaGuo,ZhenyuLin,BinQiu,GuonanChen.Anovelfluorescentsensorformutationalp53DNAsequencedetectionbasedonclickchemistry.BiosensorsandBioelectronics,2013,41,403-408.
XiaofengWei,LingyanZheng,FangLuo,ZhenyuLin*,LonghuaGuo,BinQiuandGuonanChen*.FluorescencebiosensorfortheH5N1antibodybasedonametal–organicframeworkplatform.J.Mater.Chem.B,2013,1,1812-1817.
XiZhu,HanyeZheng,XiaofengWei,ZhenyuLin,LonghuaGuo,BinQiuandGuonanChen.Metal–organicframework(MOF):anovelsensingplatformforbiomolecules.Chem.Commun.,2013,49,1276-1278.
LidanXie,HanyeZheng,WenmeiYe,SuyanQiu,ZhenyuLin,LonghuaGuo,BinQiuandGuonanChen.Novelcolorimetricmolecularswitchbasedoncopper(I)-catalyzedazide–alkynecycloadditionreactionanditsapplicationforflumioxazindetection.Analyst,2013,138,688-692.
HuifengXu,HongzhiYe,XiZhu,ShijingLiang,LonghuaGuo,ZhenyuLin,XianxiangLiuandGuonanChen.Dual-channelcathodicelectrochemiluminescenceofluminolinducedbyinjectionofhotelectronsonaniobatesemiconductormodifiedelectrode.Analyst,2013,138,234-239.
XiaojuanLi,LingyanZheng,LianzhuHuang,OuZheng,ZhenyuLin,LonghuaGuo,BinQiu,GuonanChen.Adsorptionremovalofcrystalvioletfromaqueoussolutionusingametal-organicframeworksmaterial,coppercoordinationpolymerwithdithiooxamide.JournalofAppliedPolymerScience.2013,DOI:10.1002/app.39009.
2012：
LonghuaGuo*,YuechunYin,RongHuang,BinQiu,ZhenyuLin,Huang-HaoYang,JianrongLi,GuonanChen.EnantioselectiveanalysisofmelagatranviaaLSPRbiosensorintegratedwithmicrofluidicchip.LabonaChip,2012,12(20),3901-3906.（Thisarticlewascollectedin"LabonaChipTop10%")
LonghuaGuo,Dong-HwanKim.LSPRbiomolecularassaywithhighsensitivityinducedbyaptamer-antigen-antibodysandwichcomplex.BiosensorsandBioelectronics,2012,31(1),567-570.
XiaofengWei,WenlieLin,NaMa,FangLuo,ZhenyuLin,LonghuaGuo,BinQiuandGuonanChen.Sensitivefluorescencebiosensorforfolatereceptorbasedonterminalprotectionofsmall-molecule-linkedDNA.Chem.Commun.,2012,48,6184-6186.
GuiyunZhang,WenlieLin,WeiqiangYang,ZhenyuLin,LonghuaGuo,BinQiuandGuonanChen.LogicgatesformultiplexedanalysisofHg2+andAg+.Analyst,2012,137,2687-2691.
ZhenyuLin,SenGao,JingLin,WenlieLin,SuyanQiu,LonghuaGuo,BinQiuandGuonanChen.Visualdetectionofcopper(II)basedontheaggregationofgoldnano-particlesviaclickchemistry.Anal.Methods,2012,4,612-615.
QihongCai,ChunmeiWang,JinZhou,FangLuo,ZhenyuLin,LonghuaGuo,BinQiuandGuonanChen.TerminalprotectionG-quadruplex-basedturn-onfluorescencebiosensorforH5N1antibody.Anal.Methods,2012,4,3425-3428.
HongDai,YanlingChen,YanyuLin,GuifangXu,CaipingYang,YuejinTong,LonghuaGuo,GuonanChen.Anewmetalelectrocatalystssupportedmatrix:Palladiumnanoparticlessupportedsiliconcarbidenanoparticlesanditsapplicationforalcoholelectrooxidation.ElectrochimicaActa,2012,85,644-649.
2011：
LonghuaGuo,YoujuHuang,YoshikuniKikutani,YoTanaka,TakehikoKitamori,Dong-HwanKim.Insituassembly,regenerationandplasmonicimmunosensingofaAunanorodmonolayerinaclosed-surfaceflowchannel.LabonaChip,2011,11，3299-3304.
LonghuaGuo,AbdulRahimFerhan,KijoonLeeandDong-HwanKim.Nanoarray-basedBiomolecularDetectionUsingIndividualAu-NanoparticleswithMinimizedLSPRVariations.AnalyticalChemistry,2011,83(7),2605–2612.
LonghuaGuo,Dong-HwanKim.Reusableplasmonicaptasensor:Usingasinglenanoparticletoestablishacalibrationcurveandtodetectanalytes.ChemicalCommunications,2011,47(25),7125-7127.
LonghuaGuo,XiaodongZhou,Dong-HwanKim.Facilefabricationofdistance-tunableAu-nanorodchipsforsingle-nanoparticleplasmonicbiosensors.BiosensorsandBioelectronics,2011,26,2246–2251.
LonghuaGuo,FengFuFuandGuonanChen.Capillaryelectrophoresiswithelectrochemiluminescencedetection:fundamentaltheory,apparatus,andapplications.AnalyticalandBioanalyticalChemistry,2011,399,3323-3343.
BinQiu,LinglingXue,YanpingWu,ZhenyuLin,LonghuaGuo*,GuonanChen.MechanismstudyoninorganicoxidantsinducedinhibitionofRu(bpy)32+electrochemiluminescenceanditsapplicationforsensitivedeterminationofsomeinorganicoxidants,Talanta,2011,85，339-344.
BinQiu,LonghuaGuo,ChunhuaGuo,ZhiyongGuo,ZhenyuLin,andGuonanChen.SynthesisofanewNi-phenanthrolinecomplexanditsapplicationasanelectrochemicalprobefordetectionofnucleicacid.BiosensorsandBioelectronics,2011,26,2270-2274.
BinQiu,LonghuaGuo,MingluanChen,ZhenyuLinandGuonanChen.Studyoninteractionbetweenanewfluorescentprobe2-methylbenzo[b][1,10]phenanthrolin-7(12H)-oneandBSA.Analyst,2011,136,973-978.
HailanChen,LonghuaGuo,ARFerhan,Dong-HwanKim.MultilayeredPolypyrrole-CoatedCarbonNanotubestoImproveFunctionalStabilityandElectricalPropertiesofNeuralElectrodes.JournalofPhysicalChemistryC,2011,115,5492-5499.
BinQiu,XiaofenJiang,LonghuaGuo,ZhenyuLin,ZongweiCai,GuonanChen.AhighlysensitivemethodfordetectionofproteinbasedoninhibitionofRu(bpy)32+/TPrAelectrochemiluminescentsystem.ElectrochimicaActa,2011,56(20),6962-6965.
PengSi,PalanisamyKannan,LonghuaGuo,HungsunSonandDong-HwanKim.HighlystableandsensitiveglucosebiosensorbasedoncovalentlyassembledhighdensityAunanostructures.BiosensorsandBioelectronics,2011,26,3845-3851.
HailanChen,JianminShen,LonghuaGuo,YuanChen,Dong-HwanKim.CellularresponseofRAW264.7tospray-coatedmulti-walledcarbonnanotubefilmswithvarioussurfactants.JournalofBiomedicalMaterialsResearchPartA,2011,96A(2),413–421.
HailanChen,KannanPalanisamy,LonghuaGuo,HongyuChenandDong-HwanKim.DirectgrowthofhighlybranchedsinglecrystalAunanostructuresonelectrodesurface:TheirsurfaceenhancedRamanscatteringandelectrocatalyticapplications.JournalofMaterialsChemistry,2011,21(45),18271-18278.
2010：
LonghuaGuo,GuonanChenandDong-HwanKim.Three-DimensionallyAssembledGoldNanostructuresforPlasmonicBiosensors.AnalyticalChemistry,2010,82,5147–5153.
LonghuaGuo,LinglingXue,BinQiu,ZhenyuLin,DonghwanKimandGuonanChen.MechanismstudyoninhibitedRu(bpy)32+electrochemiluminescencebetweencoreactants.PhysicalChemistryChemicalPhysics,2010,?12,12826-12832.
LonghuaGuoandDonghwanKim,Peakwavelengthdependant-localizedsurfaceplasmonresonancesensitivity,201010thIEEEConferenceonNanotechnology,NANO2010,Korea,2010,pp.267-270.
Xue-YangXiao,Long-HuaGuo*,BinQiu,Zhen-YuLin,Guo-NanChen.Capillaryelectrophoresiswithinhibitedelectrochemiluminescentdetectionforthetraceanalysisofepinephrineanddopamine.JournalofPharmaceuticalAnalysis,2010,22,77-82.
ARFerhan,LonghuaGuoandDong-HwanKim.InfluenceofIonicStrengthandSurfactantConcentrationonElectrostaticSurfacialAssemblyofCetyltrimethylammoniumbromide-cappedGoldNanorodsonFully-ImmersedGlassrs.Langmuir,2010,26,14,12433-12442.
YanboZeng,LilingCai,HaidongWang,LeiLi,WeijingYou,LonghuaGuo,GuonanChen.Resonancelightscatteringstudyontheinteractionbetweenquinidinesulfateandcongoredanditsanalyticalapplication.Luminescence,2010,25(1),30–35.
2009：
LonghuaGuo,HuanghaoYang,BinQiu,XueyangXiao,LinlinXue,DonghwanKimandGuonanChen.Capillaryelectrophoresiswithelectrochemiluminescentdetectionforhighlysensitiveassayofgeneticallymodifiedorganisms.AnalyticalChemistry,2009,81,23,9578-9584.
LonghuaGuo,BinQiu,LinlinXue,GuonanChen.CEwithanewelectrochemiluminescentdetectionsystemforseparationanddetectionofproteinslabeledwithtris(1,10-phenanthroline)ruthenium(II).Electrophoresis,2009,30,2390–2396.
LonghuaGuo,GuonanChen.Applicationsofcapillaryelectrophoresisandmicrochipcapillaryelectrophoresisforthedetectionofgeneticallymollifiedfood.FoodScienceandBiotechnology,2009,18,823-832.
LonghuaGuo,BinQiu,MingxingChen,GuonanChen.Anewmethodforpreparationofetchedporousjointforcapillaryelectrophoresisanditspore-sizeevaluation.Electrophoresis,2009,30,1355–1361.
BinQiu,LonghuaGuo,ZhitaoChen,YuwuChi,LanZhang,GuonanChen,SynthesisofN-4-butylamineacridoneanditsuseasfluorescentprobeforctDNA,BiosensorsandBioelectronics,2009,24,1281–1285.
LinglingXue,LonghuaGuo,BinQiu,ZhenyuLin,andGuonanChen.MechanismforinhibitionofRu(bpy)32+/DBAEelectrochemiluminescencesystembydopamine.ElectrochemistryCommunications,2009,11(8),1579-1582.
2007-2008：
LonghuaGuo,BinQiu,YingyanJiang,ZuyaoYou,GuonanChen,Capillaryelectrophoresischemiluminescentdetectionsystemequippedwithatwo-steppostcolumnflowinterfacefordetectionofsomeenkephalin-relatedpeptideslabeledwithacridiniumester,Electrophoresis.2008,29,2348-2355.
LonghuaGuo,BinQiu,YuwuChi,GuonanChen.UsingmultiplePCRandcapillaryelectrophoresiswithchemiluminescencedetectionforsimultaneousqualitativeandquantitativeanalysisofgeneticallymodifiedorganism.Electrophoresis,2008,29,3801-3809.
LonghuaGuo,BinQiu,GuonanChen,Synthesisandinvestigationontheinteractionwithcalfthymusdeoxyribonucleicacidofanovelfluorescentprobe7-oxobenzo[b][1,10]phenanthroline-12(7H)-sulfonicacid,AnalyticaChimicaActa,2007,588,123-130.
BinQiu,LonghuaGuo,WeiWang,GuonanChen,SynthesisofanovelfluorescentprobeusefulforDNAdetection，BiosensorsandBioelectronics,2007,22,2629-2635.
获奖情况
福建省科技进步二等奖（2012年）；
福建省优秀博士论文(2011年)；
卢嘉锡优秀研究生奖（2008.10）。
其他
中国福建省福州市福州地区大学新区学园路2号福州大学化学化工学院杨鸿耀楼401；邮编:350108
