个人简介：冯尚源（教授/博导，福建省光子技术重点实验室副主任）长期从事表面增强拉曼光谱在疾病无损检测领域研究，在国际核心期刊共发表论文80多篇，以第一作者或通讯作者发表SCI一、二区论文37篇，相关论文在Google学术总引用超过2000多次，其中一篇SCI一区论文被评为年度高引用论文。此外，冯尚源还申请获得10项发明专利。主持国家自然科学基金项目三项，并作为骨干成员参与两项国家基金重点项目。曾获2016年福建省高等学校新世纪优秀人才计划资助。相关研究成果荣获2017年福州青年科技奖（1/1），2016年福建省科学技术进步奖一等奖（4/5）以及2016年福建省自然科学奖二等奖（3/5）等多项奖励。


研究方向:生物医学光学、光谱与光学成像
10篇代表性论文：
[1].Feng Shangyuan,Zheng Z, Xu Y, Lin J, Chen G,et al.,A noninvasive cancer detection strategy based on gold nanoparticle surface-enhanced Raman spectroscopy of urinary modified nucleosides isolated by affinity chromatography.Biosensors and Bioelectronics, 2017,91(15): 616-622. (SCI一区，IF 8.17)
[2].Duo Lin,Yi-Cheng Lin,Shangwei Yang,Lan Zhou,Weng Kee Leong,Shangyuan Feng*, andKien Voon Kong*, Organometallic-constructed Tip-based Dual Chemical Sensing by Tip-enhanced Raman Spectroscopy for Diabetes Detection.ACS Appl. Mater. Interfaces, 2018,10(49)：41902-41908,(SCI一区，IF 8.09)
[3].Duo Lin,Tianxun Gong,Zi-Yao Hong,Sufang Qiu,Jianji Pan,Chinh-Yu Tseng,Shangyuan Feng*,Rong Chen*, andKien Voon Kong*.Metal Carbonyls for the Biointerference-Free Ratiometric SERS-based Assay forCell-Free Circulating DNA of Epstein-Barr Virus in Blood.Analytical Chemistry, 2018, 90 (12): 7139-7147.(SCI一区，IF 6.04)
[4].Jinyong Lin, Lingdong Shao, Sufang Qiu, Xingwu Huang, Mengmeng Liu, Zuci Zheng, Duo Lin andShangyuan Feng*. Application of a near-infrared laser tweezers Raman spectroscopy system for label-free analysis and differentiation of diabetic red blood cells,Biomedical Optics Express,2018, 9(3): 984-993(SCI光学二区, IF 3.48)
[5].Mengmeng Liu, Xiujie Liu, Zufang Huang,Hang Fai Kwok*, Yao Lin*,Shangyuan Feng*, Rapid discrimination of colon cancer cells with single base mutation in KRAS gene segment using laser tweezers Raman spectroscopy,Journal of Biophotonics, 2019, e(SCI二区, IF 3.76，封面论文)
[6].Xueliang Lin, Lingna Wang, Huijing Lin, Duo Lin*, Jinyong Lin,Shangyuan Feng*, A novel urine analysis technique combining affinity chromatography with Au nanoparticle based surface enhanced Raman spectroscopy for potential applications in non‐invasive cancer screening, Journal of Biophotonics, 2019, e(SCI二区, IF 3.76,封面论文)
[7].D Lin, Z Zheng, Q Wang, H Huang, Z Huang, Y Yu, S Qiu, andS Feng*,Label-free optical sensor based on red blood cells laser tweezers Raman spectroscopy analysis for ABO blood typing.Optics Express, 2016,24(21): 24750-24759(SCI二区, IF 3.15)
[8].Lin D, Wu Q, Qiu S, Chen G,Feng S*, Chen R, Zeng H*.Label-free liquid biopsy based on blood circulating DNA detection using SERS-based nanotechnology for nasopharyngeal cancer screening.Nanomedicine. 2019 , 22:102100. doi: 10.1016/j.nano. (SCI二区，IF 4.3)
[9].Lin X, Wang Y, Wang L, Lu Y, Li J, Lu D, Zhou T, Huang Z, Huang J, Huang H, Qiu S, Chen R, Lin D*,Feng S*.Interference-free and high precision biosensor based on surface enhanced Raman spectroscopy integrated with surface molecularly imprinted polymer technology for tumor biomarker detection in human blood.Biosensors and Bioelectronics,2019 , 143:111599. doi: 10.1016/j.bios.2019.111599. (SCI一区，IF 10.25)
[10].Lin D, Wang Y, Wang T, Zhu Y*, Lin X, Lin Y*,Feng S*.Metabolite profiling of human blood by surface-enhanced Raman spectroscopy for surgery assessment and tumor screening in breast cancer.Anal Bioanal Chem. 2020 , 412(7):1611-1618. doi: 10.1007/s00216-020-02391-4. (SCI二区, IF 3.63)
主要科研项目:
1.国家自然科学基金面上项目，**，基于拉曼光谱与多光子显微镜联用系统的肺癌循环肿瘤细胞检测研究，2020.1-2023.12，59万，主持；
2.国家自然科学基金面上项目，**，基于尿液肿瘤标志物SERS与SEROA光谱技术的食道癌筛查研究，2016.1-2019.12, 61万，主持；
3.国家自然科学基金青年项目，**，活性鼻咽癌细胞激光光镊表面增强拉曼光谱研究，2012.1-2014.12，25万，主持；
4.福建省高校产学合作项目支持计划，2020Y4006，基于血液表面增强拉曼光谱技术的恶性肿瘤筛查关键技术及仪器研制，2020.8-2023.12，40万，主持；
Email：syfeng@fjnu.edu.cn