博、硕士研究生导师简介




个人简历：
陶武成，生理学博士。福建医科大学基础医学院教授，博导，“闽江****”****。博士毕业于美国华盛顿大学 （University of Washington), 随后在加州大学旧金山分校从事博士后研究，师从美国科学院院士，神经生物学泰斗Roger Nicoll教授。应用电生理，分子生物学及光遗传学等方法系统地研究离子通道，受体，突触传递，环路功能，以及整体动物行为，来阐述大脑功能及相关疾病。目前的课题涉及：（1）离子通道和受体的生物物理特性，生理功能及药理;（2）神经突触传递的分子机制及信号转导；（3）突触可塑性；（4）学习与记忆;（5）学习与记忆异常相关的疾病，比如老年痴呆症。目前已发表SCI论文10篇，其中以第一作者在PNAS（IF=10）、Molecular Psychiatry（IF=13.6，封面文章）等国际知名杂志发表4篇论文，相关成果曾被Nature等杂志重点推荐和评论。在Frontiers（IF=4.0）等杂志担任审稿编委。
发表文章：
1.Tao W, Ma C, Bemben M, Li K, Burlingame A, Zhang M, and Nicoll RA. (2019). Mechanisms underlying the synaptic trafficking of the glutamate delta receptor GluD1. Molecular Psychiatry. (cover paper)
2.Tao W, Alonso JD, Sheng NY, and Nicoll RA. (2018). Postsynaptic delta1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and presynaptic neurexin. PNAS 115: E5373-E5381.
3.Duan GF, Ye Y, Xu S, Tao W, Zhao S, Jin T, Nicoll RA, Shi YS, Sheng N. (2018) Signal peptide represses GluK1 surface and synaptic trafficking through binding to amino-terminal domain.Nat Commun 19;9(1):4879.
4.Sheng N, Bemben MA, Díaz-Alonso J, Tao W, Shi YS, Nicoll RA. (2018). LTP requires postsynaptic PDZ-domain interactions with glutamate receptor/auxiliary protein complexes.PNAS 115(15):3948-3953.
5.Tao W, Higgs MH, Spain WJ, Ransom CB. (2013). Postsynaptic GABAB receptors enhance extrasynaptic GABAA receptor function in dentate gyrus granule cells. J Neurosci 33:3738-3743. (Highlighted as featured article and comment by Nature Review Neuroscience)
6.Ransom CB, Tao W, Wu Y, Spain WJ, Richerson GB. (2013). Rapid regulation of tonic GABA currents in cultured rat hippocampal neurons. J Neurophysiol 109:803-812.
7.Li M, Chen M, Huang H, Tao W, Cui J, Xiang H. (2011). Neuroprotective effects of active ingredients isolated from Pegasus laternarius on cultured cerebral neurons. Cell Mol Neurobiol 31:73-82.
8.Cui J, Hu W, Cai Z, Liu Y, Li S, Tao W, Xiang H. (2010). New medicinal properties of mangostins: analgesic activity and pharmacological characterization of active ingredients from the fruit hull of Garcinia mangostana L. Pharmacol Biochem Behav 95:166-172.
9.Wang K, Cui J, Cai Y, Wang F, Li Y, Tao W, Xiang H. (2009). Critical roles of voltage-dependent sodium channels in the process of synaptogenesis during the postnatal cortical development of rats. Cell Mol Neurobiol 29:1131-1142.
10.Xiang H*, Tao W*, Wang L, Wang F, Xu A. (2008). The effect of recombinant
neurotoxins from the sea anemone Anthopleura sp. on sodium currents of rat cerebral cortical neurons. Cell Mol Neurobiol 28:1119-1128. (*Co-first author)