陈雷， 2009 年师从韩国庆北大学 Kang Young-Hwa 教授( 首尔大学,药学博士)，于 2015 年获得博士学位。

教育背景
? 2011.3-2015.2. 庆北大学农业生命科学学院，应用生命科学专业农学博士 (Ph. D.)
? 2009.3-2011.2. 庆北大学农业生命科学学院， 应用生命科学专业农学硕士 (M.S.E.)

工作简历
? 2015.08-至今 福建农林大学 副教授待遇

? 2015.3-2015.6 庆北大学生命研究所 博士后研究员

主要获奖情况
? 2009.3 – 2015.3 韩国政府奖学金

? 2014.12. 优秀博士论文发表奖(top 1%)

个人业绩
? 2011-2015 年 博士在读期间任学科助教，指导并完成 41 名本科毕业论文，并担任天然产物成分析/统计学的双语（英语和韩语）教学工作。
? 2009-2015 年 近 5 年来前后主持/参与韩国农业发展厅、庆尚北道农业科技部科研课题 11 项，从事天然产物活性因子的分离纯化及其功能评价和功能保健食品的开发。

独立审稿经历
? Food Research International (8)
? Journal of Separation Science (3)
? Natural Product Research (4),
? International Journal of Food Properties (4)
? Medicinal Chemistry Research (5)


? Journal of the Science of Food and Agriculture (1)
? Phytomedicine (3)

研究方向
? 食药品的功能成分生理活性和安全性的检测：

单体化合物的活性分析有助于解析和认识功能性活性组分。目前的研究工作主要从活性←结构特征→作用机理两个方向着手，系统探究功能性成分活性的构效机制。博士期间做了大量的不同溶液提取物和单体的体内外抗氧化、抗
炎（LPS-诱导炎症巨噬细胞和小鼠）、抗癌（癌细胞实验）、抗糖尿（体外和 STZ-诱导小鼠实验）活性比较，对活性物质的抗病机理以及信号通路分析具有比较好的研究基础。
? 计算化学生物学

以分子模拟、生物信息学和化学信息学为手段，研究重要生物大分子的功能和机制，研究有机小分子和生物大分子相互作用的基本理论，发展和完善计算机辅助药物设计方法。运用计算机辅助药物设计方法并结合必要的化学和生
物实验手段，寻找和设计可以有效调节重大疾病靶标分子功能的有机小分子化合物。

主要论文发表情况 (含 in press 阶段)
1. Chen L., Kang Y.H. Antioxidant and Enzyme Inhibitory Activities of Plebeian Herba
(Salvia plebeia R. Br.) under Different Cultivation Conditions. Journal of Agricultural and Food
Chemistry (Impact Factor: 3.38), 2014, 62: 2190-2197. (JCR 二区， 第一作者)
2. Chen L., Kang Y.H., Suh J.K. Roasting processed oriental melon (Cucumis melo L. var. makuwa
Makino) seed influenced the triglyceride profile and the inhibitory potential against key enzymes
relevant for hyperglycemia. Food Research International (Impact Factor: 2.818): 2014, 56: 236-242.
(JCR 二区，第一作者)
3. Chen L., Hwang J.E., Choi B. et al. Antioxidant capacities and cytostatic effect of Korean red
pepper (Capsicum annuum L): a screening and in vitro study. Journal of the Korean Society for
Applied Biological Chemistry. 2014, 57: 43-52. (JCR 四区，第一作者)
4. Chen L., Kang Y.H. Hypoglycaemic activity of oriental melon (cucumis melo l. var. makuwa
makino) seeds and its active compounds. The Plant Resources Society of Korea. 2014, 27,
622- 628（ SSCI, Korea, 第一作者）
5. Chen L., Kang Y.H. Antioxidant Activities of Agrimonia pilosa Ledeb: In Vitro
Comparative
Activities of Its Different Fractions. Korean J. Plant Res, 2014, 27(6): 642-649. （ SSCI, Korea,
第一作者）
6. Chen L., Kang Y.H. Anti-inflammatory and antioxidant activities of red pepper
(Capsicum
annuum L.) stalk extracts: Comparison of pericarp and placenta extracts. Journal of
Functional Foods (Impact Factor: 4.48), 2013, 5: 1724-1731. (JCR 二区，第一作者)

7. Chen L., Kang Y.H. In vitro inhibitory effect of oriental melon (Cucumis melo L. var. makuwa
Makino) seed on key enzyme linked to type 2 diabetes: Assessment of anti-diabetic
potential of functional food. Journal of Functional Foods (Impact Factor: 4.48) 2013, 5(2):
981-986. (JCR 二区，第一作者)
8. Chen L., Kang Y. H. In vitro inhibitory potential against key enzymes relevant for hyperglycemia
and hypertension of red pepper (Capsicum annuum L.) including pericarp, placenta, and
stalk. Journal of Food Biochemistry (Impact Factor: 1.155), 2013, 38: 300-306. (JCR 四区，第一作者)
9. Chen L., Hwang J.E., Gu K.M. et al. Comparative study of antioxidant effects of five Korean
varieties red pepper (Capsicum Annuum. L) extracts from various parts including placenta, stalk,
and pericarp. Food Science and Biotechnology (Impact Factor: 1.449), 2012, 21: 715-721. (JCR 四区，
第一作者).
10. Chen L., Kang Y.H. Effect of roasting on anti-inflammatory activity of oriental melon (Cucumis
melo l. Var. Makuwa) seeds. International Conference on Agriculture Science and
Environment Engineering (EI).
11. Chen L., Kang Y.H. Identification and characterization of major α-glucosidase inhibitors from
Agrimonia pilosa Ledeb. Chemistry & Biodiversity (in press, impact factor: 1.95). (JCR 四区， 第一作者)
12. Huang Q., Chen L.* et al., 2015 Phenolic compounds ameliorate the glucose uptake in HepG2
Cells Insulin Resistance via activating AMPK. Journal of Functional Foods. 2015, 19,
487-494. (JCR 二区，通讯作者)
13. Teng H., Chen L.*. Compounds from Agrimonia pilosa Ledeb modulating glycogen synthesis
and enhancing glucose consumption in insulin-resistance HepG2 cells. Food and Function (in press,
impact factor: 2.91). (JCR 二区，第一作者)
14. Teng H., Chen L.*. "α-Glucosidase and α-amylase inhibitors from seed oil: a review
of
liposoluble substance to treat diabetes. Critical Reviews in Food Science and Nutrition (accepted,
impact factor: 5.54). (JCR 一区，第一作者)
15. Chen L., Yu R.H., Ni X., Yanbo K. Z., Szkudelski T., Fan J., Makarova E., Xu B.B., Xiao J.
Natural polyphenols in the treatment of type 2 diabetes: Human studies and clinical trial. Current
Medicinal Chemistry (impact factor: 3.82). Invited Paper. (JCR 二区，第一作者)
16. Chen L., Teng H., Huang Q., Wang J., Lin Q. et al., Microwave-assisted Extraction of Oil, Fatty
Acids from Raspberry Seed and Antioxidant Analysis: Evaluation of cytoprotective effect in HepG2
cells. Food Chemistry (in press, impact factor: 3.39). (JCR 二区， 第一作者)
17. Chen L., Teng H., Lee W.Y., Song. H.B. Ultrasonic-assisted extraction of raspberry seed oil and
evaluation of its physicochemical properties, fatty acid compositions and antioxidant
activities. Plosone, (in press, impact factor: 3.39). (JCR 三区，第一作者)
18. Teng H., Chen L., Lee W.Y. Mathematical Modeling of Thin-layer Drying Kinetics of Blue-
berried Honeysuckle (Lonicera caerulea var. Venulosa). Journal of the Korean Society for Applied
Biological Chemistry. (2nd reversion submitted, impact factor: 0.69). (JCR 四区，第二作者)
19. Chen L., Teng H., Xiao J.* Agrimonolide from Agrimonia pilosa suppresses
inflammatory
responses through down-regulation of COX-2/iNOS and inactivation of NF-κB
in lipopolysaccharide- stimulated macrophages. Phytomedicine. Impact factor: 3.04 ((JCR 二区， 第一作者)
20. Chen L., Teng H., Xiao J.* Structural modifications of flavonoids required for efficient anti-
inflammatory activity: Update on Structure-Activity Relationship Critical Reviews in Food Science
and Nutrition (submitted, impact factor: 5.54). (JCR 一区，第一作者)