张静博士，福建农林大学生命科学学院化学生物学系，副教授，硕士生导师。入选“福建省高等学校新世纪优秀人才支持计划”、“福建省高校****科研人才计划”、“福建省卫生系统学术技术带头人后备人才”、福建农林大学“金山****”拔尖人才和学术新秀、“福建农林大学****科技人才培养”计划。先后主持国家自然科学基金、福建省自然科学基金、福建省医学创新基金等多项科研项目。发表SCI论文多篇，培养的一名研究生获得国家奖学金。




教育经历
1997年9月－2001年7月，山西大学，应用化学系，学士。
2001年9月－2004年7月，福州大学，化学化工学院分析化学专业，硕士。
2007年9月－2011年7月，福州大学，化学化工学院分析化学专业，博士。





工作经历
2011年10月至今，福建农林大学，生命科学学院，副教授，硕士生导师。
2016年12月－2017年12月，美国普渡大学，国家公派访问****。




荣誉及奖励
福建省自然科学优秀学术论文三等奖
福建农林大学“青年五四奖章”
福建省技术发明二等奖（排名第四）。
福建农林大学严家显最高奖教金。
福建省优秀博士论文学位论文三等奖。











研究领域
纳米电化学、光学可视化生物传感技术和电致化学发光生物传感技术及其在真菌毒素、肿瘤相关基因、蛋白和金属离子检测方面的研究。




开授课程
无机及分析化学
实验化学
现代仪器分析实验
专业导论




科研项目
1、用于肺癌外泌体检测的DNA纳米树生物传感器的研制（WKJ2016-2-30），福建省卫生教育联合攻关计划项目，2017.1- 2019.12。
2、基于DNA 纳米树的赭曲酶毒素A 电化学适体传感器的研制（2016J01042），福建省自然科学基金，2016.4-2019.3。
3、基于DNA自组装和DNA模拟酶技术的多通道电化学适体传感器用于农产品中多种真菌毒素的协同检测（JA13088），福建省高等学校新世纪优秀人才支持计划，2014.1- 2016.12。
4、用于多种真菌毒素联合检测的多通道电化学适体传感器的研制（xjq201407），2014.5- 2017.12。
5、基于无酶循环放大策略的多通道纳米电化学生物传感器用于肝癌多元肿瘤标志物的联合检测（**），国家自然科学基金，2013.1- 2015.12。
6、用于唾液快速检测乳腺癌的生物传感器的研制（2011-CX-22），福建省医学创新基金，2011.9-2014.9。
7、超灵敏非标记型电化学生物传感器用于唾液中乳腺癌相关基因的非创伤性检测（2011J01028），福建省自然科学基金，2011.4-2014.3。
8、拉链核酸探针纳米电化学生物传感器测定转基因植物特定序列的研究（JA10295），福建省高校****科研人才计划，2010.3-2013.3。
9、用于快速检测肝癌相关蛋白的核酸适配体生物传感器的研制（**），福建省卫生厅青年基金，2010.3-2013.3。




论文著作
1.Yaokun Xia, Wenhui He, Juan Li, Lupeng Zeng, Tingting Chen, Yijuan Liao, Weiming Sun, Jianming Lan, Shuangmu Zhuo, Jing Zhang*, Huanghao Yang*, and Jinghua Chen*, Acridone Derivate Simultaneously Featuring Multiple Functions andIts Applications,Anal. Chem. 2019, 91, 8406?8414.
2. Lipei Luo,1, Liangliang Wang,1, Lupeng Zeng, Yuru Wang, Yunping Weng, Yijuan Liao,Tingting Chen, Yaokun Xia, Jing Zhang*, Jinghua Chen*,A ratiometric electrochemical DNA biosensor for detection of exosomalMicroRNA, Talanta 2020, 207,120298.
3. JingZhang, Liang-Liang Wang, Mei-Feng Hou, Li-Pei Luo, Yi-JuanLiao, Yao-Kun Xia, An Yan, Yun-PingWeng, Lu-Peng Zeng, Jing-HuaChen,Label-free fluorescent and electrochemical biosensors based on defective G-quadruplexes，Biosensors and Bioelectronics, 2018, 118, 1-8.
4. Jing Zhang, Liang-Liang Wang, Mei-Feng Hou, Yao-Kun Xia, Wen-Hui He, An Yan, Yun-Ping Weng, Lu-Peng Zeng, Jing-Hua Chen*, A ratiometric electrochemical biosensor for the exosomal microRNAs detection based on bipedal DNA walkers propelled by locked nucleic acid modified toehold mediate strand displacement reaction,Biosensors and Bioelectronics, 2018, 102, 33-40.
5. Jing Zhang,Dong-Zhi Wu,Shu-Xian Cai,Mei Chen,Yao-Kun Xia,Fang Wu,Jing-Hua Chen*,An immobilization-free electrochemical impedance biosensor based on duplex-specific nuclease assisted target recycling for amplified detection of microRNA,Biosensors and Bioelectronics, 2016, 75, 452-457.
6. Jing Zhang, Yao-Kun Xia，Mei Chen,Dong-Zhi Wu,Shu-Xian Cai,Meng-Meng Liu,Wen-Hui He, Jing-Hua Chen*,A Fluorescent Aptasensor based on DNA-scaffolded Silver Nanoclusters Coupling with Zn(Ⅱ)-ion Signal-enhancement for Simultaneous Detection of OTA and AFB1, Sensors and Actuators B, 2016,235, 79-85.
7. Jing Zhang, Dongzhi Wu, QiuXiang Chen, Mei Chen, Yaokun Xia, Shuxian Cai, Xi Zhang, Fang Wu, Jinghua Chen*, Label-Free MicroRNA Detection based on Terbium and Duplex-Specific Nuclease Assisted Target Recycling，Analyst, 2015,140, 5082-5089.
8. Shuxian Cai, Guangwen Li, Xi Zhang, Yaokun Xia, Mei Chen, Dongzhi WuQiuxiang Chen,Jing Zhang*, JinghuaChen*，A signal-on fluorescent aptasensor based on single-stranded DNA-sensitized luminescence of terbium (III) for label-free detection of breast cancer cells. Talanta, 2015, 138, 225-230.
9. Xi Zhang,Dongzhi Wu, Zhijing Liu, Shuxian Cai, Yanping Zhao, Mei Chen, Yaokun Xia, Chunyan Li, Jing Zhang^*and Jinghua Chen^*, An ultrasensitive Label-Free Electrochemical Biosensor for MicroRNA-21 Detection based on 2’-O-methyl modified DNAzyme and Duplex-Specific Nuclease Assisted Target Recycling，Chemical Communications, 2014, 50, 12375-12377.
10. Xi Zhang, Jing Zhang*, Dongzhi Wu, Zhijing Liu, Shuxian Cai, Mei Chen, Yanping Zhao, Chunyan Li, Huanghao Yang*, Jinghua Chen*, Ultraselective Electrochemiluminescence Biosensor Based on Locked Nucleic Acid Modified Toehold-Mediated Strand Displacement Reaction and Junction-probe, Analyst, 2014, 139,6109-6112.
11. Jinghua Chen, Xi Zhang, Shuxian Cai, Dongzhi Wu, Mei Chen, Shihua Wang^*, Jing Zhang^*, A Fluorescent Aptasensor based on DNA-Scaffolded Silver-Nanocluster for Ochratoxin A Detection, Biosensors and Bioelectronics, 2014,57, 226-231.
12. Jinghua Chen, Jia Lin, Xi Zhang, Shuxian Cai, Dongzhi Wu, Chunyan Li, Sheng Yang*, Jing Zhang*, Label-free fluorescent biosensor based on the target recycling and Thioflavin T-induced quadruplex formation for short DNA species of c-erbB-2 detection, Anal Chim Acta.2014, 817, 42-47.
13. Jinghua Chen*, Xi Zhang, Shuxian Cai, Dongzhi Wu, Jia Lin, Chunyan Li, Jing Zhang*, Label-free electrochemical biosensor using home-made 10-methyl-3-nitro-acridone as indicator for picomolar detection of nuclear factor kappaB, Biosensors and Bioelectronics, 2014, 53, 12-17.
14. Jing Zhang, XiaoYan Wu, WeiJuan Yang, JingHua Chen*, FengFu Fu*, Ultra-sensitive electrochemical detection of single nucleotide polymorphisms based on an electrically controllable magnetic gold electrode, Chem. Commun.2013，49, 10, 996-998.
15. Jing Zhang, Xi Zhang, Guidi Yang, Jinghua Chen*, Shihua Wang, A signal-on fluorescent aptasensor based on Tb(³⁺) and structure-switching aptamer for label-free detection of Ochratoxin, Biosensors & Bioelectronics. 2013,15, 41, 704-709.
16. Jing Zhang, Jinghua Chen*, Xi Zhang, Zhigao Zeng, Mei Chen, Shihua Wang, An electrochemical biosensor based on hairpin-DNA aptamer probe and restrictionendonuclease for ochratoxin A detection, Electrochemistry Communications. 2012, 25(25): 5-7.
17. Jing Zhang, Pingping Chen, XiaoYan Wu, JingHua Chen*, LiangJun Xu, GuoNan Chen, FengFu Fu, A signal-on electrochemiluminescence aptamer biosensor for the detection of ultratrace thrombin based on junction-probe.Biosensors and Bioelectronics, 2011, 26(5): 2645-2650.
18. Jing Zhang, QingLan Gao, PingPing Chen, JingHua Chen*, GuoNan Chen, FengFu Fu. A novel Tb³⁺-promoted G-quadruplex-hemin DNAzyme for the development of label-free visual biosensors. Biosensors and Bioelectronics, 2011, 26(10): 4053-4057.
19. Jing Zhang, XiaoYan Wu, PingPing Chen, NingTing Lin, JingHua Chen*, GuoNan Chen, FengFu Fu. Electrochemical genotyping and detection of single-nucleotide polymorphisms based on junction-probe containing 2'-deoxyinosine. Chem. Commun., 2010, 46(37): 6986-6988.
20.Jing Zhang, Jing Hua Chen, Rong Chun Chen, Guo Nan Chen, Feng Fu Fu*. Sequence-specific detection of trace DNA via a junction-probe electrochemical sensor employed template-enhanced hybridization strategy. Biosensors and Bioelectronics, 2009, 25(4): 815-819.
21. Jing Zhang,Jing Hua Chen, Rong Chun Chen, Guo Nan Chen, Feng Fu Fu*. Biosensors and Bioelectronics, 2009, 25(2): 378-382.

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