姓名：林焱性别：女
政治面貌：中共党员出生年月：1988.11最高学位：博士
职 称：助理研究员联系方式：18850138341
邮箱：ylin19@fafu.edu.cn

个人简历
2016.8-至今 福建农林大学，助理研究员
从事蜂产品中生物活性成分的分离鉴定和药理活性研究。 2014.9-2016.2 中国科学院生物物理研究所，博士后
从事老年痴呆疾病标志物抗体的研发。
2011.9-2014.7 Queen’s University Belfast，药学，博士
研究两栖动物皮肤分泌物中生物活性肽的分离纯化、结构鉴定、cDNA 克隆及其生物功能。参与医学院免疫与感染中心由国际牙科研究协会/葛兰素史克联合资助的口腔护理创新研究：LL-37
的模拟肽作为新药的研究。
2007.9-2011.7 福建中医药大学，药物制剂专业，学士

研究领域及方向：
天然药物和抗体药物的研发

研究成果（含发表论文）：发表论文：
1. Yan Lin, Qiqi Shao, Meng Zhang, Chenyue Lu, Joy Fleming, Songkun Su. Royal jelly-derived
proteins enhance proliferation and migration of human epidermal keratinocytes in an in vitro
scratch wound model. BMC Complementary and Alternative Medicine. 2019, 19: 175.
2. Yan Lin*, Nan Hu, Tianbao Chen, Mei Zhou, Lei Wang, Chris Shaw. A Hylarana latouchii skin
secretion-derived novel bombesin-related pentadecapeptide (ranatensin-HLa) evoke myotropic effects
on the in vitro rat smooth muscles.

Toxins. 2019, 11, 204.
3. Yan Lin*, Tianbao Chen, Mei Zhou, Lei Wang, Songkun Su, Chris Shaw. Ranatensin-HL: a
bombesin-related tridecapeptide from the skin secretion of the broad-folded frog, Hylarana
latouchii. Molecules. 2017, 22 (7): 1110.
4. Yan Lin*, Haiying Hang, Tianbao Chen, Mei Zhou, Lei Wang, Chris Shaw. pLR-HL: a novel amphibian
Bowman-Birk-type trypsin inhibitor from the skin secretion of the broad-folded frog, Hylarana
latouchii. Chemical biology & drug design. 2016, 87 (1): 91-100.
5. Yan Lin, Nan Hu, Peng Lyu, Jie Ma, Lei Wang, Mei Zhou, Suhua Guo, Tianbao Chen, Chris Shaw.
Hylaranins: prototypes of a new class of amphibian antimicrobial peptide from the skin secretion of
the Oriental broad-folded frog, Hylarana latouchii. Amino acids. 2014, 46 (4): 901–909.
6. Bingjie Kong, Yang Cao, Danni Wu, Lili An, Fanlei Ran, Yan Lin, Chen Ye, Hailin Wang, Haiying
Hang. Affinity maturation of an antibody for the UV-induced DNA lesions 6, 4
pyrimidine-pyrimidones. Applied Microbiology and Biotechnology. 2018, 02 (15): 6409-6424.
7. Hongyi Nie, Haiyang Geng, Yan Lin, Shupeng Xu, Zhiguo Li, Yazhou Zhao, Songkun Su. Genome-wide
identification and characterization of Fox genes in the honeybee, Apis cerana, and comparative
analysis with other bee Fox genes. International journal of genomics. 2018, 2018: 5702061.
8. Hongyi Nie, Shupeng Xu, Cuiqin Xie, Haiyang Geng, Yazhou Zhao, Jianghong Li, Wei?fone Huang, Yan
Lin, Zhiguo Li, Songkun Su. Comparative transcriptome analysis of Apis mellifera antennae of
workers performing different tasks. Molecular genetics and genomics. 2018, 293 (1): 237-248.
9. Shuang Sun, Xiao Yang, Haifeng Wang, Yun Zhao, Yan Lin, Chen Ye, Xiangdong Fang, Haiying Hang.
Antibody affinity maturation through combining display of two-chain paired antibody and precision
flow cytometric sorting. Applied Microbiology and Biotechnology. 2016, 100 (13): 5977-5988.
10. Xinping Xi, Renjie Li, Yingchun Jiang, Yan Lin, Yuxin Wu, Mei Zhou, Jie Xu, Lei Wang, Tianbao
Chen, Chris Shaw. Medusins: a new class of antimicrobial peptides from the skin secretions of
phyllomedusine frogs. Biochimie. 2013, 95 (6): 1288-1296.
11. Yuxin Wu, Lei Wang, Chen Lin, Yan Lin, Mei Zhou, Liang Chen, Brain Connolly, Yingqi Zhang,
Tianbao Chen, Chris Shaw. Vasorelaxin: a novel arterial smooth muscle-relaxing eicosapeptide from
the skin secretion of the Chinese piebald odorous frog (Odorrana schmackeri). PLoS One. 2013, 8
(2): e55739.
“*”: corresponding author.科研项目：

1. 福建省自然科学基金面上项目：蜂王浆主蛋白 MRJP2、MRJP3 和 MRJP7 在伤口愈合过程中的作用及机制研究（2019J01408），主持
2. 国家自然科学基金青年项目: 体外快速人工进化抗体技术的研究（31500753），主持
3. 福建农林大学 A 类毕业生科研启动费，主持