张子平，男，1964 年生，博士，教授，博导，闽江学者，福建省高校领军人才，福建省引进高层次人才国外C 类。
电子邮箱：zhangziping@hotmail.com; zhangziping@fafu.edu.cn

QQ: 1525147980
微信：ZipingZhang



研究领域及方向：1. 水产动物分子免疫，
2. 水生应激生理和抗逆育种，
3. 水产动物生殖调控。
主要成果：
主持中国国家自然基金项目（NSFC）、美国国立卫生研究院（National Institutes of Health， NIH）、美-加国际合作五大湖渔业委员会（The Great Lakes
Fishery Commission，GFLC）、中国国家攻关项目、科技部重点研发项目、农业部重点项目等科研项目。作为主要参与者参与国际科学基金（International Foundation
for Science，IFS）项目 1 项、中国国家自然基金项目 7 项，中国 863 项目 2 项，美国路易斯安娜州鱼类与野生生物署项目 1 项、及其它省部级项目约 15 项。获福
建省科学技术奖二等奖 1 项。在水产动物缺氧/高温应激机制开展了一系列的研究，首次发现鱼类的缺氧诱导型 GLUT、PI3K-AKT
通路参与鲍的缺氧/高温的免疫抑制等。在水产动物生殖生物学开展了多年的系列研究，率先证实传统认为是管家蛋白的核糖体蛋白基因在对虾雌雄生殖腺差异表达等。已发表研究论文 160 余篇（其中 SCI 收录
60 余篇），多篇论文获中国水产学会等多个学术组织的奖励，其中获福建省自然科学优秀论文一等奖 1 项。是 20
多个国际英文期刊，及哈萨克斯坦科学基金等多个国际科学基金组织的评审专家。教育部高等学校水产类专业教学指导委员会委员，福建省动物学会常务理事，福建省水产原良种评审委员会委员。
现有主要研究项目：
1. 鲍抗逆性状的遗传与分子机制（科技部重点研发项目，2018YFD0900304-5，主持）
2. 拟穴青蟹特异性免疫致敏的分子机制及眼柄在其中的作用（NSFC 31672681，主持）
3. 饲用型抗刺激隐核虫益生菌浓缩制剂的研发推广 （福建省科技厅高校产学合作项目，
2017N5002，主持）
4. 定点诱变培育速生河豚新品系 （福建省种业创新与产业化项目，KLG18H01A，主持）
5. 拟穴青蟹 VIH 的转录调控机制研究 （NSFC31472266，参加）
6. 修饰mRNA 法建立大黄鱼诱导多能干细胞 （NSFC41306174，参加）
7. 拟穴青蟹的卵巢发育机制及膏蟹培育饲料的研发

8. 水产动物应激性疾病发生的分子机制及分子诊断技术的建立
9. 环境应激的表观遗传学效应

近 5 年发表的论文（部分）(part of published peer-reviewed articles in recent 5-year)

1. Zhang X, Shi JL, Sun YL, Habib YJ, Yang HP, Zhang ZP*, Wang YL*. Integrative transcriptome
analysis and discovery of genes involving in immune response of hypoxia/thermal challenges in the
small abalone Haliotis diversicolor. Fish Shellfish Immunol. 2019. 84:609-626. doi:
10.1016/j.fsi.2018.10.044.
2. Zhang X, Shi JL, Sun YL, Zhu YF, Zhang ZP*, Wang YL*. Transcriptome analysis provides insights
into differentially expressed genes and long noncoding RNAs involved in sex-related differences in
Amur sturgeon (Acipenser schrenckii). Mol Reprod Dev. 2019, 86(2):132-144. doi: 10.1002/mrd.23065.
3. Fang ZQ, Sun YL, Zhang X, Wang GD, Li YT, Wang YL*, Zhang ZP*. Responses of HSP70 gene to
Vibrio parahaemolyticus infection and thermal stress and its transcriptional regulation analysis in
Haliotis diversicolor. Molecules. 2019, 24(1). pii: E162. doi: 10.3390/molecules24010162.
4. Feng JJ, Lin P, Wang YL, Zhang ZP. Molecular characterization, expression patterns, and
functional analysis of toll-interacting protein (Tollip) in Japanese eel Anguilla japonica. Fish
Shellfish Immunol. 2019. 90:52-64. doi: 10.1016/j.fsi.2019.04.053.
5. Wang T, Lin P, Guo SL, Wang YL, Zhang ZP, Feng JJ. Molecular characterization and expression
analysis of signal transducer and activator of transcription 1 (STAT1) in Japanese eel Anguilla
japonica. Fish Shellfish Immunol. 2019, 86:956-964. doi: 10.1016/j.fsi.2018.12.046.
6. Zhou MC, Jia X, Wan HF, Wang SH, Zhang X, Zhang ZP*, Wang YL. miR-34 regulates reproduction by
inhibiting the expression of MIH, CHH, EcR, and FAMeT genes in mud crab Scylla paramamosain. Mol
Reprod Dev. 2019. 86(2):122-131. doi: 10.1002/mrd.23063.
7. Zhang X, Huang DP, Jia XW, Zou ZH, Wang YL, Zhang ZP*. Functional analysis of the promoter of
the molt-inhibiting hormone (mih) gene in mud crab Scylla paramamosain. Gen Comp Endocrinol. 2018,
259:131-140. doi: 10.1016/j.ygcen.2017.11.014.
8. Liu CY, Jia XW, Zou ZH, Wang XW, Wang YL, Zhang ZP*. VIH from the mud crab is specifically
expressed in the eyestalk and potentially regulated by transactivator of Sox9/Oct4/Oct1. Gen Comp
Endocrinol. 2018, 255:1-11. doi: 10.1016/j.ygcen.2017.09.018.
9. Jia XW, Zhou MC, Zou ZH, Lin P, Wang YL, Zhang ZP*. Identification and

comparative analysis of the ovary and testis microRNAome of mud crab Scylla paramamosain. Mol
Reprod Dev. 2018. 85(6):519-531. doi: 10.1002/mrd.22989.
10. Han KH, Dai YB, Zhang ZP, Zou ZH, Wang YL. Molecular Characterization and Expression Profiles
of Sp-uchl3 and Sp-uchl5 during Gonad Development of Scylla paramamosain. Molecules. 2018.
19:23(1). pii: E213. doi: 10.3390/molecules23010213.
11. Han KH, Chen SH, Cai MY, Jiang YH, Zhang ZP*, Wang YL*. Nanos3 not nanos1 and nanos2 is a germ
cell marker gene in large yellow croaker during embryogenesis. Comp Biochem Physiol B Biochem Mol
Biol. 2018. 218:13-22. doi:10.1016/j.cbpb.2018.01.002.
12. Jiang YH, Han KH, Chen SH, Cai MY, Wang YL*, Zhang ZP*. Molecular cloning and expression of
Octamer-binding transcription factor (Oct4) in the large yellow croaker, Larimichthys crocea. Gene
Expr Patterns. 2018. 27:16-30. doi:10.1016/j.gep.2017.10.001.
13. Li YT, Zhang T, Zhang X, Wang GD, Wang YL*, Zhang ZP*. Heat shock cognate 70 gene in Haliotis
diversicolor: responses to pathogen infection and environmental stresses and its transcriptional
regulation analysis. Cell Stress & Chaperones.2018, 23(3):335- 346.
14. Jiang YH, Han KH, Cai, MY, Wang YL*, Zhang ZP*. Characterization and spatio- temporal
expression of Klf4 in large yellow croaker Larimichthys crocea. DNA and Cell Biology. 2017, 36(8):
655-671.
15. Jiang YH, Han KH, Chen SH, Wang YL*, Zhang ZP*. Isolation, characterization, and expression of
proto-oncogene cMyc in large yellow croaker Larimichthys crocea. Fish Physiology and Biochemistry.
2017, 43:1443–1461.
16. He LH, Zhang X, Yang HP, Wang YL, Zhang ZP*. The Characterization of RHEB gene and its
responses to hypoxia and thermal stresses in the small abalone Haliotis diversicolor. Comparative
Biochemistry and Physiology. Part B, Biochemistry & Molecular Biology, 2017, 210:48-54.
17. Feng JJ*, Lin P, Guo SL, Jia YY, Wang YL, Zadlock F, Zhang ZP. Identification and
characterization of a novel conserved 46 kD maltoporin of Aeromonas hydrophila as a versatile
vaccine candidate in European eel (Anguilla anguilla). Fish & Shellfish Immunology. 2017,
64:93-103.
18. Feng JJ*, Lin Peng, Wang YL, Guo SL, Zhang ZP, Yu LL. Identification of a type I interferon
(IFN) gene from Japanese eel and its expression analysis in vivo and in vitro. Arig Gene. 2017,
5:19-26.
19. Zhang X, Sun YY, Wang GD, Lin S, Zeng XY, Wang YL*, Zhang ZP*. PI3K-AKT signaling pathway is
involved in hypoxia/thermal-induced immunosuppression of small abalone Haliotis diversicolor. Fish
Shellfish Immunol. 2016, 59:492-508.[pubmed]
20. Jiang YH, Han KH, Chen SH, Wang YL, Zhang ZP. Characterization and expression analysis of
Lc-Sox4 in large yellow croaker Larimichthys crocea. Comp Biochem Physiol B Biochem Mol Biol. 2016,
196-197:1-10. [pubmed]

21. Rana SB, Zadlock FJ, Zhang ZP, Murphy WR, Bentivegna CS. Comparison of De Novo Transcriptome
Assemblers and k-mer Strategies Using the
Killifish, Fundulus heteroclitus. PLoS ONE. 2016, 11(4): e0153104.
doi:10.1371/journal.pone.0153104. [pubmed]
22. Feng JJ, Guo SL, Lin P, Wang YL, Zhang ZP, Zhang Z, Yu LL. Identification of a retinoic
acid-inducible gene I from Japanese eel (Anguilla japonica) and expression analysis in vivo and in
vitro. Fish Shellfish Immunol. 2016, 55:249-56. [pubmed]
23. Wang GD, Li N, Zhang LL, Zhang LH, Zhang ZP, Wang YL*. IGFBP7 is involved in abalone
metamorphosis. Aquaculture. 2016, 451: 377–384 [ScienceDirect].
24. Chen S, Pu L, Xie F, Zou Z, Jiang Y, Han K, Wang Y, and Zhang ZP*: Differential expression of
three estrogen receptors mRNAs in tissues, growth development, embryogenesis and gametogenesis from
large yellow croaker, Larimichthys crocea. Gen Comp Endocrinol. 2015, 216:134–151. [pubmed]
25. Jiang YH, Han KH, Chen SH, Hong WH, Wang YL*, Zhang ZP. Molecular cloning, characterization and
expression of Lc-Sox11a in large yellow croaker Larimichthys crocea. Gene. 2015, 574:287-301.
[pubmed]
26. Wang GD, Li N, Zhang LL, Zhang LH, Zhang ZP, Wang YL*. IGFBP7 promotes hemocyte proliferation
in small abalone Haliotis diversicolor, proved by dsRNA and cap mRNA exposure.Gene.2015, 571:65-70.
[pubmed]
27. Wang GD, Zhang ZP, Lin S, Zhang LL, Wang BZ, Wang SH, Wang YL*. A homologue of dermatopontin
from Haliotis diversicolor and its response to pathogenic infection. Aquaculture Research.
2015,46(7):1537-1549.[wiley]
28. Gao J, Wang XW, Zou ZH, Jia XW, Wang YL, and Zhang ZP*: Transcriptome analysis of the
differences in gene expression between testis and ovary in green mud crab (Scylla paramamosain).
BMC Genomics 2014, 15:585 [pubmed]
29. Zhang X, Huang YY, Cai XH, Zou ZH, Wang GD, Wang SH, Wang YL, Zhang ZP*. Identification and
expression analysis of immune-related genes linked to Rel/NF-κB signaling pathway under stresses
and bacterial challenge from the small abalone Haliotis diversicolor. Fish Shellfish Immunol. 2014,
41:200-208 [pubmed]
30. Huang YT, Cai XH, Zou ZH, Wang SH, Wang GD, Wang YL, Zhang ZP* Molecular cloning,
characterization and expression analysis of three heat shock responsive genes from Haliotis
diversicolor. Fish & Shellfish Immunology. 2014, 36(2):590-599. [pubmed].
31. Cai XH, Huang YT, Zhang X, Wang SH, Zou ZH, Wang GD, Wang YL, Zhang ZP*. Cloning,
characterization, hypoxia and heat shock response of hypoxia inducible factor-1 (HIF-1) from the
small abalone Haliotis diversicolor. Gene. 2014, 534(2):256-264. [pubmed]

Professor Ziping Zhang
Email: zhangziping@hotmail.com; zhangziping@fafu.edu.cn
QQ: 1525147980
WeChat: ZipingZhang






Research interests:

1) Aquatic Stress Physiology and Breeding for Stress Tolerance;
2) Aquatic Molecular Immunology;
3) Aquatic Reproduction Physiology;


Prof. Zhang received his Ph.D. from the City University of Hong Kong. He completed his postdoctoral
training from the Michigan State University. He spent four years in the Texas State University as a
Research Assistant Professor, two years in the Seton Hall University as a Tenure Track Assistant
Professor, and two and a half years in the New York State University of Agriculture and Technology
as a Tenure Track Assistant Professor. Now he is a Specifically Appointed Professor of Fujian
Agriculture and Forestry, Leading University Professor of Fujian Province. Dr. Zhang is also a
council member of the Teaching Steering committee of Aquatic Specialty in Colleges and Universities
of the Ministry of Education, executive Director of Fujian Zoological Society, a council member of
the committee of Aquatic Genetics Resources and Aquatic Breeding of Fujian Province.
Dr. Zhang has received more than twenty research grants from the National Natural Science
Foundation of China (NSFC), the National Key Research and Development Project of China, the
National Institutes of Health (NIH, USA), the Great Lakes Fisheries Commission (GLFC, USA

& Canada), and other agencies. He has published over 160 peer-reviewed articles and received
several academic awards from various academic organizations such as the Chinese Fisheries Society.
His research demonstrated that spike structure of the shrimp sperm, previously described as a tail
in many text books, was the acrosome of the sperm de facto. His manuscript from this work was
awarded “excellent article” by the Chinese Society of Fisheries. He is the one who identified the
first hypoxia responsive glucose transporter from fish, and demonstrated that the ribosomal protein
L24 which was traditionally believed as a house-keeping gene was differentially expressed between
the testis and ovary of shrimp.
Dr. Zhang has a lot of experience to review academic articles that were submitted to top journals
in the field, to review research proposals that were submitted to NIH, NSFC, National Centre of
Science and Technology Evaluation of Kazakhstan, and other scientific foundations. He has also been
servicing as a technical consultant to provide professional guidance for the industry for many
years.

Current research projects:

1. 2018- PI. Heredity and molecular mechanism of stress-resistance traits of abalone.
Source of Funding: the National Key Research and Development Project of China. (Award Number:
2018YFD0900304-5).
2. 2017- PI. Molecular mechanism of specific immune priming and function of eyestalk in
specific immune priming in Scylla paramamosain. Source of Funding: National Science Foundation of
China (NSFC). (Award Number: 31672681).
3. 2018- PI. Application of genome editing in innovation and industrialization of Fugu
seed industry. Source of Funding: Fujian Marine and Fisheries Bureau. (Award Number: KLG18H01A).
4. 2016- PI. Special research grant awards for Leading University Professor of Fujian
Province. Source of Funding: Fujian Education Bureau.